Key Largo Luxury Vacations
Book a Luxury Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to ￥45,448 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Top Luxury Key Largo Hotels
Playa Largo Resort & Spa, Autograph Collection
97450 Overseas Highway, Key Largo, FL
Playa Largo Resort & Spa, Autograph Collection is one of the Key Largo luxury 4.5-star beach properties where you can treat yourself to pillowtop beds, Netflix, ...
8.8/10 Excellent! (1,005 reviews)
"really nice beach"
Reviewed on Jul 19, 2025
The Pelican Key Largo Cottages
99340 Overseas Highway, Key Largo, FL
The Pelican Key Largo Cottages offers a luxury stay. Popular amenities include a private beach, a marina, and a terrace.
8.6/10 Excellent! (1,001 reviews)
Enjoyable
"The location was great and the cottage was really clean (except for the sugar ants in the kitchen) & cute. The furniture was very dated and the pink sofa was quite stained. However, the beds were soft and comfortable. Large dining table and even an outdoor patio. You can walk to the restaurant nextdoor. ..."
Reviewed on Jul 18, 2025
Bayside Inn Key Largo
99490 Overseas Hwy, Key Largo, FL
Spoil yourself with a luxury vacation in Key Largo. Popular amenities include a private beach, an outdoor pool, and a restaurant.
8.6/10 Excellent! (1,534 reviews)
"Great place pool could have been cleaned"
Reviewed on Jul 16, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More Vacation Ideas
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.