Mesopotamia Cheap Vacations

Book a Cheap Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ¥45,448 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top Cheap vacation packages in Mesopotamia

Price found within the past 48 hours. Click for updated prices.
Exe Hotel Cataratas
Gran Melia Iguazú
Loi Suites Iguazú Hotel
Hotel Saint George
Don't see what you're looking for?
See all available trips from Osaka to Mesopotamia
View all trips

5* Cheap vacations in Mesopotamia

Price found within the past 48 hours. Click for updated prices.
Exe Hotel Cataratas
Gran Melia Iguazú
Loi Suites Iguazú Hotel
Don't see what you're looking for?
See all available trips from Osaka to Mesopotamia
View all trips

4 Night Cheap vacations in Mesopotamia

Price found within the past 48 hours. Click for updated prices.
La Aldea de la Selva Lodge
Gran Melia Iguazú
Loi Suites Iguazú Hotel
Don't see what you're looking for?
See all available trips from Osaka to Mesopotamia
View all trips

Top Cheap Mesopotamia Hotels

Hotel Nacional Inn Foz do Iguaçu

Hotel Nacional Inn Foz do Iguaçu

3 out of 5
Rod. Das Cataratas, Km 16,7 Foz do Iguaçu PR
  • 17 hours drive from Termas de Federacion
Book a stay at this family-friendly hotel in Foz do Iguaçu. Enjoy free breakfast, free WiFi, and room service. Our guests praise the overall value in our reviews. ...
8.2/10 Very Good! (686 reviews)
Clean rooms nice stuff.

Reviewed on Mar 10, 2026

Hotel Nacional Inn Foz do Iguaçu
Hotel Saint George

Hotel Saint George

4 out of 5
Avenida Cordoba 148 Puerto Iguazú Misiones
  • 17 hours drive from Termas de Federacion
Book a stay at this spa hotel in Puerto Iguazú. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,003 reviews)
Very nice hotel, clean room with nice bathroom shower. And close proximity to restaurants in the area. Excellent breakfast with a large variety and friendly staff. Enjoyed our stay there

Reviewed on Mar 19, 2026

Hotel Saint George
Residencial Los Lapachos

Residencial Los Lapachos

2.5 out of 5
Los Lapachos Nº 584 Puerto Iguazú Misiones
  • 17 hours drive from Termas de Federacion
Stay at this B&B in Puerto Iguazú. Enjoy free WiFi, breakfast (surcharge), and daily housekeeping. Popular attractions Three Borders Landmark and Cataratas Avenue ...
8.2/10 Very Good! (47 reviews)
close to public transport
Convenient to public transport and two supermarkets. Bus from the airport will drop you off there. Lovely service with limited English. Good breakfast included. Only downside is no kettle or tea/coffee in rooms.

Reviewed on Aug 6, 2018

Residencial Los Lapachos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.