Mesopotamia Vacations from ￥252,308

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The Latest Mesopotamia Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Infinito Hotel

Infinito Hotel

3 out of 5
Palermo
Price was ￥312,502, price is now ￥252,308 per person
￥252,308
per person
Nov 13 - Nov 19
found 10 hours ago
Roundtrip flight included
Osaka (OSA) to Buenos Aires (BUE)
7.6/10 Good! (213 reviews)
This hotel is like an upscale hostel. Rooms are clean, staff was incredibly nice and helpful. Breakfast was a step up from continental. The sidewalks in front were torn up so harder to navigate to the door with suitcases. But not their fault. Thecardkey is used to turn on the electricity, so make sure you get two. The elevators are super old school with the pull gates and one was so tiny two people could squeeze into it. The hot tub is not a hot tub, but cold. The rooftop deck is fine, but up super skinny steep stairs. The main issue was the noise. We were next to a Health Club that played music all day till 10 at night Every day. Again the staff were awesome and it was clean.

Reviewed on Apr 21, 2024

Estancia Villa Maria

Estancia Villa Maria

3.5 out of 5
Save 100% on your flight
Price was ￥646,774, price is now ￥366,830 per person
￥366,830
per person
Nov 13 - Nov 19
found 10 hours ago
Roundtrip flight included
Osaka (OSA) to Buenos Aires (BUE)
9.4/10 Exceptional! (97 reviews)
We had an incredible stay. It was very relaxing. The staff is exceptional. The villa itself is very charming. It’s about 45 minutes from the city we had a car and would spend the day in the city and come back in the afternoon for a peaceful break.

Reviewed on Aug 6, 2025

Live Soho Boutique Apartments Devoto

Live Soho Boutique Apartments Devoto

4 out of 5
Villa Devoto
Price was ￥413,731, price is now ￥298,647 per person
￥298,647
per person
Nov 13 - Nov 19
found 10 hours ago
Roundtrip flight included
Osaka (OSA) to Buenos Aires (BUE)
No reviews
Faena Hotel Buenos Aires

Faena Hotel Buenos Aires

5 out of 5
Puerto Madero
Save 100% on your flight
Price was ￥1,470,142, price is now ￥1,077,890 per person
￥1,077,890
per person
Nov 13 - Nov 19
found 10 hours ago
Roundtrip flight included
Osaka (OSA) to Buenos Aires (BUE)
9/10 Wonderful! (451 reviews)
GREAT LOCATION / BEAUTIFUL PROPERTY

Reviewed on Aug 20, 2025

Arc Recoleta Boutique Hotel & Spa

Arc Recoleta Boutique Hotel & Spa

4 out of 5
Recoleta
Price was ￥338,129, price is now ￥290,462 per person
￥290,462
per person
Nov 13 - Nov 19
found 10 hours ago
Roundtrip flight included
Osaka (OSA) to Buenos Aires (BUE)
9/10 Wonderful! (1,002 reviews)
Limpio, staff muy atento, habitaciones comodas y pensadas para la comodidad.

Reviewed on Jul 8, 2025

Find the Best Mesopotamia Vacation Packages

Mesopotamia Hotel Deals

Hotel y Spa Termas del Este

Hotel y Spa Termas del Este

3 out of 5
Presidente Raúl alfonsín 877, Federacion
Fully refundableReserve now, pay when you stay
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Hotel y Spa Termas del Este
Hathor Concordia

Hathor Concordia

3 out of 5
Ruta Nacional 14-km 264.5, Concordia, Entre Rios
Fully refundableReserve now, pay when you stay
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Hathor Concordia
Costarenas Hotel & Spa

Costarenas Hotel & Spa

3.5 out of 5
12 de Abril y Quiros, Colon, Entre Rios
Fully refundableReserve now, pay when you stay
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Costarenas Hotel & Spa
See all 500 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mesopotamia vacation package cost?
Maybe less than you might think — from only ￥252,308, actually! By combining hotels, flights and car rentals into your own tailor-made package, your Mesopotamia escape is just a few clicks away.
How do I get a cheap travel package to Mesopotamia?
Crafting your own Mesopotamia vacation package with Expedia is a great way to save. We offer more than 550 partner airlines and 1,000,000 hotels across the globe. With such a broad range to choose from, you'll have no worries creating your next dream adventure.
What are the top hotels in Mesopotamia?
Costarenas Hotel & Spa and Hotel Queguay know how to make their guests feel welcome in Colon. If your itinerary also includes Parana, check out Mayim Hotel Termal & Spa and Costarenas Hotel & Spa. Both are very popular with travelers.
How far in advance should I book my Mesopotamia vacation?
It all depends on the airline, but you can usually compare international fares on Expedia nearly a year in advance. While it's generally a good idea to book ahead of time, lucky travelers occasionally nab a cheaper ticket just weeks before departure dates.
What does an Expedia Mesopotamia travel package include?
You can choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can add the fun stuff like experiences and activities. Want to pick your fare class? That's also easy to do. The choice is all yours when it comes to arranging your perfect Mesopotamia trip.
What should I know before booking a Mesopotamia travel package?
Booking all the parts of your getaway together is a smart way to save. Bundle your flights, car rentals and hotels into a convenient package. But it's not just hotels. Expedia has all types of properties, including vacation rentals such as mountain cabins and serviced residences. The list is almost endless!
Can I choose my airline with a Mesopotamia Expedia vacation package?
Yes, and with over 550 airlines to select from worldwide, you're not short on choice. Search the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Mesopotamia vacation package?
Don't worry if you're rethinking your Mesopotamia vacation package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We realize life can throw the occasional spanner in the works, so head to our Customer Service Portal if that occurs. When you're ready to make changes, we'll take care of it.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.