A river winding through a dense forest.

Find hotels in Mesopotamia from ļæ„5,357

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
Nov 6 - Nov 8
In two weeks
Nov 13 - Nov 15

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Mesopotamia hotels

A covered outdoor swimming pool with lounge chairs and a waterfall feature.

1. Hathor Concordia

Hathor Concordia
3.0 star property
Concordia
8.8 out of 10, Excellent, (393 reviews)
"EVERYTHING WAS GOOD"
Australia
Jose
The price is ļæ„9,337
ļæ„9,337 total
Dec 1 - Dec 2
Hathor Concordia
A hotel with a well-lit exterior, a wooden fence, and a garden with various plants and a palm tree.

2. Club Valle Termal Resort

Club Valle Termal Resort
3.0 star property
Federacion
9.2 out of 10, Wonderful, (95 reviews)
"Hh"
United States
Luis
The price is ļæ„9,416
ļæ„9,416 total
Dec 2 - Dec 3
Club Valle Termal Resort
A swimming pool with clear water, surrounded by palm trees and a modern building in the background.

3. Mayim Hotel Termal & SPA

Mayim Hotel Termal & SPA
3.0 star property
Concordia
9.6 out of 10, Exceptional, (11 reviews)
"Muy bien las piscinas, excelente el personal y la comida del hotel "
Costa Rica
Federico
The price is ļæ„13,329
ļæ„13,329 total
Dec 2 - Dec 3
Mayim Hotel Termal & SPA
A hotel with a sign reading "OMARAN SUITES & Towers" at night, illuminated by purple lighting.

4. Maran Suites & Towers - Hotel & Spa

Maran Suites & Towers - Hotel & Spa
3.5 star property
Parana
9.0 out of 10, Wonderful, (35 reviews)
"Great location and friendly, accommodating staff. "
United States
Michael
The price is ļæ„16,492
ļæ„16,492 total
Nov 2 - Nov 3
Maran Suites & Towers - Hotel & Spa
A pool area with a fountain, palm trees, and a paved walkway.

5. Turismo Hotel Casino

Turismo Hotel Casino
4.5 star property
Corrientes
9.4 out of 10, Exceptional, (11 reviews)
"The best place to stay in Corrientes! Amazing views "
United States
Laura
The price is ļæ„12,876
ļæ„12,876 total
Nov 29 - Nov 30
Turismo Hotel Casino
Pool

6. HOTEL TERMAS VICTORIA Wellness Spa

HOTEL TERMAS VICTORIA Wellness Spa
4.0 star property
Victoria
8.8 out of 10, Excellent, (3 reviews)
"Es un lugar tranquilo ideal para descansar un par de dĆ­as. El personal es lo mejor del lugar sin dudas, fueron muy atentos en todo momento. Lo Ćŗnico que creo que podrĆ­an mejorar es el tema de la pileta, en el momento que fui hacĆ­a frĆ­o pero no habĆ­a otra oferta como por ejemplo una pileta climatizada, y para utilizar el Yacuzzi o el sauna habĆ­a que pagar extra. Generalmente a los hoteles spa que he ido esto estĆ” incluido. Solo un detalle. VolverĆ­a sin dudarlo, pero con un poco mĆ”s de calor."
Spain
Mariela Emilia
The price is ļæ„19,076
ļæ„19,076 total
Nov 2 - Nov 3
HOTEL TERMAS VICTORIA Wellness Spa
An aerial view of a resort with a large swimming pool, multiple buildings, and a parking area.

7. Hotel y Spa Termas del Este

Hotel y Spa Termas del Este
3.0 star property
Federacion
8.6 out of 10, Excellent, (13 reviews)
"good for a 1 night stay"
Canada
Chase
The price is ļæ„8,623
ļæ„8,623 total
Nov 2 - Nov 3
Hotel y Spa Termas del Este
A swimming pool with steps leading into it, surrounded by lounge chairs and umbrellas, with a building in the background.

8. Complejo La Loma

Complejo La Loma
3.0 star property
Federacion
8.2 out of 10, Very good, (13 reviews)
"Had a very good experience here. Hosts do not speak English, but were very patient with me as I used Google Translate to communicate. Woman at the desk was very kind. I had arrived late and was able to check in without issue. The suite is great - there is a full bathroom, bedroom and kitchen / dining area. There is a communal pool outside in the courtyard as well with lounge chairs. Breakfast was decent as well. Parking on site. I would stay here again for sure, but would be better for multiple...
Canada
Logan
The price is ļæ„6,488
ļæ„6,693 total
Nov 9 - Nov 10
Complejo La Loma
A room with wicker chairs, a wooden table, and a view of a body of water through large windows.

9. Costarenas Hotel & Spa

Costarenas Hotel & Spa
3.5 star property
Colon
8.8 out of 10, Excellent, (65 reviews)
"spectacular since we arrived the tstaff was wonderful and kind to us very helpful and nice answering all our questions, the hotel very comfortable!! the river view stunning"
Argentina
Lisette
The price is ļæ„19,144
ļæ„19,144 total
Nov 2 - Nov 3
Costarenas Hotel & Spa
A terrace with a view of a sunset over a body of water, featuring a small island and a row of chairs.

10. Intersur Colon

Intersur Colon
3.0 star property
ColĆ³n
8.0 out of 10, Very good, (11 reviews)
"Is ok "
United States
Carla
The price is ļæ„15,802
ļæ„15,802 total
Nov 2 - Nov 3
Intersur Colon
A large house with a swimming pool surrounded by lush greenery and a river in the background.

11. La Regina Lodge

La Regina Lodge
4.0 star property
Municipo de Itati
9.0 out of 10, Wonderful, (2 reviews)
"Excelente pousada, piscina fantƔstica com visual do rio"
Brazil
Marcos
The price is ļæ„9,035
ļæ„9,035 total
Nov 18 - Nov 19
La Regina Lodge
A restaurant with tables set for dining, featuring red chairs and a glass partition wall.

12. Rio Arriba Suites Apartments y Resto

Rio Arriba Suites Apartments y Resto
3.5 star property
Bella Vista
8.6 out of 10, Excellent, (4 reviews)
"Pessoal da recepĆ§Ć£o excelente acolhimento. Hotel bonito, falta manutenĆ§Ć£o em certos lugares. Quarto Ć³timo, cama com colchĆ£o selado e barulho nos ares condicionados. CafĆ© da manhĆ£ deixa a desejar. Restaurante muito bonito. "
Brazil
Anonymous traveler
The price is ļæ„9,252
ļæ„9,252 total
Nov 9 - Nov 10
Rio Arriba Suites Apartments y Resto
A spacious lobby with black and red seating, a reception desk, and a staircase connecting two levels.

13. O2 Hotel GualeguaychĆŗ

O2 Hotel GualeguaychĆŗ
2.5 star property
GualeguaychĆŗ
7.8 out of 10, Good, (98 reviews)
"Clean, convenient and friendly staff."
United States
Christian
The price is ļæ„7,210
ļæ„7,210 total
Nov 2 - Nov 3
O2 Hotel GualeguaychĆŗ
A hotel exterior with a stone facade, a well-lit entrance, and a paved area with small trees.

14. Hotel Rio

Hotel Rio
3.0 star property
ChajarĆ­
8.4 out of 10, Very good, (16 reviews)
"Nao vale um centavo"
Brazil
Eduardo
The price is ļæ„13,519
ļæ„13,519 total
Nov 2 - Nov 3
Hotel Rio
A modern indoor swimming pool with a wooden deck, large windows offering a view of the sea and boats.

15. Donsuites Apart Hotel

Donsuites Apart Hotel
3.0 star property
Corrientes
8.6 out of 10, Excellent, (111 reviews)
"Loved this place, super clean, and the staff were very nice and helpfulšŸ˜"
United States
Nora
The price is ļæ„10,957
ļæ„10,957 total
Nov 2 - Nov 3
Donsuites Apart Hotel
A breakfast buffet with various food items, a coffee machine, and a toaster.

16. Ayres Inn

Ayres Inn
3.0 star property
Federal
The price is ļæ„10,588
ļæ„10,588 total
Nov 2 - Nov 3
Ayres Inn
A hotel room with two beds, a dining table, a vase with flowers, and a large painting on the wall.

17. Hotel Dinastie Palace

Hotel Dinastie Palace
3.0 star property
ChajarĆ­
The price is ļæ„16,796
ļæ„16,796 total
Nov 4 - Nov 5
Hotel Dinastie Palace
A cozy room with a wooden interior, a large window with a view, a chandelier, and a flat-screen TV.

18. La Alondra Casa De HuƩspedes

La Alondra Casa De HuƩspedes
4.0 star property
Corrientes
9.4 out of 10, Exceptional, (81 reviews)
"a romantic, spacious oasis with lovely old world charm and a delicious breakfast."
United States
Ken
The price is ļæ„15,110
ļæ„15,110 total
Nov 15 - Nov 16
La Alondra Casa De HuƩspedes
Living area

19. Estancia IberĆ”

Estancia IberĆ”
3.0 star property
Mercedes
10.0 out of 10, Exceptional, (1 review)
"we had a wonderful experience the staff was very friendly and helpful and took us out on lots of activities and we saw an amazing amount of wildlife in a very short period of time. The place is very beautiful and tranquil. I would highly recommend it and give it five stars. "
Canada
orit
The price is ļæ„15,595
ļæ„15,595 total
Nov 3 - Nov 4
Estancia IberĆ”
A swimming pool with a night-time view of buildings, palm trees, and a staircase.

20. Complejo Anjana

Complejo Anjana
3.5 star property
FederaciĆ³n
9.4 out of 10, Exceptional, (3 reviews)
"Nice quiet location in nice neighborhood. Recommend"
United States
jeff
The price is ļæ„8,168
ļæ„8,168 total
Nov 9 - Nov 10
Complejo Anjana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Vacation Rentals in Mesopotamia

Condo
A hotel with a well-lit exterior, a wooden fence, and a garden with various plants and a palm tree.
Club Valle Termal Resort

Club Valle Termal Resort

Club Valle Termal Resort
3.0 star property
Federacion
9.2 out of 10, Wonderful, (95 reviews)
"Hh"
Club Valle Termal Resort
See all vacation rentals

Hotels recommended for families in Mesopotamia

A covered outdoor swimming pool with lounge chairs and a waterfall feature.

Hathor Concordia

Hathor Concordia
3.0 star property
Concordia
8.8 out of 10, Excellent, (393)
The price is ļæ„9,337
ļæ„9,337 total
Dec 1 - Dec 2
Hathor Concordia
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Mesopotamia attractions

A dirt path through a dense palm tree forest.

El Palmar National Park

8.0/10 (2 reviews)
Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay.
See properties

Learn more about Mesopotamia

The awe-inspiring IguazĆŗ Falls is the centerpiece attraction of this northeastern Argentine region, which also hosts the countryā€™s biggest carnival celebration.

See all hotels in Mesopotamia
A series of waterfalls surrounded by dense green forest.

Top Mesopotamia Hotel Reviews

O2 Hotel GualeguaychĆŗ

O2 Hotel GualeguaychĆŗ

10/10 Excellent
"Clean, convenient and friendly staff."
Christian 8-night trip
Posted 2 days ago
O2 Hotel GualeguaychĆŗ

More cheap stays in Mesopotamia

Como en casa

Como en casa

San Luis 948 8B Rosario Santa Fe
The price is ļæ„5,357 per night from Nov 4 to Nov 5
ļæ„5,357
ļæ„5,357 total
Nov 4 - Nov 5
8.4/10 Very Good! (7 reviews)

Hotels in Mesopotamia with star-rating