A river winding through a dense forest.

Find hotels in Mesopotamia from ￥5,388

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Nov 13 - Nov 15
Next weekend
Nov 20 - Nov 22

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Mesopotamia hotels

A hotel with a well-lit exterior, a wooden fence, and a garden with various plants and a palm tree.

1. Club Valle Termal Resort

Club Valle Termal Resort
3.0 star property
Federacion
9.2 out of 10, Wonderful, (95 reviews)
"Hh"
United States
Luis
The price is ￥9,997
￥9,997 total
Dec 10 - Dec 11
Club Valle Termal Resort
A covered outdoor swimming pool with lounge chairs and a waterfall feature.

2. Hathor Concordia

Hathor Concordia
3.0 star property
Concordia
8.8 out of 10, Excellent, (393 reviews)
"EVERYTHING WAS GOOD"
Australia
Jose
The price is ￥9,135
￥9,135 total
Dec 1 - Dec 2
Hathor Concordia
A swimming pool with clear water, surrounded by palm trees and a modern building in the background.

3. Mayim Hotel Termal & SPA

Mayim Hotel Termal & SPA
3.0 star property
Concordia
9.6 out of 10, Exceptional, (12 reviews)
"Muy bien las piscinas, excelente el personal y la comida del hotel "
Costa Rica
Federico
The price is ￥12,214
￥12,214 total
Dec 10 - Dec 11
Mayim Hotel Termal & SPA
A hotel with a sign reading "OMARAN SUITES & Towers" at night, illuminated by purple lighting.

4. Maran Suites & Towers - Hotel & Spa

Maran Suites & Towers - Hotel & Spa
3.5 star property
Parana
9.0 out of 10, Wonderful, (35 reviews)
"Great location and friendly, accommodating staff. "
United States
Michael
The price is ￥16,588
￥16,588 total
Nov 14 - Nov 15
Maran Suites & Towers - Hotel & Spa
A pool area with a fountain, palm trees, and a paved walkway.

5. Turismo Hotel Casino

Turismo Hotel Casino
4.5 star property
Corrientes
8.8 out of 10, Excellent, (12 reviews)
"The best place to stay in Corrientes! Amazing views "
United States
Laura
The price is ￥11,342
￥11,342 total
Nov 29 - Nov 30
Turismo Hotel Casino
A terrace with a view of a sunset over a body of water, featuring a small island and a row of chairs.

6. Intersur Colon

Intersur Colon
3.0 star property
Colón
8.0 out of 10, Very good, (11 reviews)
"Is ok "
United States
Carla
The price is ￥15,892
￥15,892 total
Nov 10 - Nov 11
Intersur Colon
An aerial view of a resort with a large swimming pool, multiple buildings, and a parking area.

7. Hotel y Spa Termas del Este

Hotel y Spa Termas del Este
3.0 star property
Federacion
8.6 out of 10, Excellent, (13 reviews)
"good for a 1 night stay"
Canada
Chase
The price is ￥8,674
￥8,674 total
Nov 10 - Nov 11
Hotel y Spa Termas del Este
A large house with a swimming pool surrounded by lush greenery and a river in the background.

8. La Regina Lodge

La Regina Lodge
4.0 star property
Municipo de Itati
9.0 out of 10, Wonderful, (2 reviews)
"Excelente pousada, piscina fantástica com visual do rio"
Brazil
Marcos
The price is ￥8,352
￥8,352 total
Nov 12 - Nov 13
La Regina Lodge
A room with wicker chairs, a wooden table, and a view of a body of water through large windows.

9. Costarenas Hotel & Spa

Costarenas Hotel & Spa
3.5 star property
Colon
8.8 out of 10, Excellent, (65 reviews)
"spectacular since we arrived the tstaff was wonderful and kind to us very helpful and nice answering all our questions, the hotel very comfortable!! the river view stunning"
Argentina
Lisette
The price is ￥19,255
￥19,255 total
Nov 10 - Nov 11
Costarenas Hotel & Spa
A spacious lobby with black and red seating, a reception desk, and a staircase connecting two levels.

10. O2 Hotel Gualeguaychú

O2 Hotel Gualeguaychú
2.5 star property
Gualeguaychú
7.8 out of 10, Good, (98 reviews)
"Clean, convenient and friendly staff."
United States
Christian
The price is ￥7,252
￥7,252 total
Nov 10 - Nov 11
O2 Hotel Gualeguaychú
A modern indoor swimming pool with a wooden deck, large windows offering a view of the sea and boats.

11. Donsuites Apart Hotel

Donsuites Apart Hotel
3.0 star property
Corrientes
8.6 out of 10, Excellent, (111 reviews)
"Loved this place, super clean, and the staff were very nice and helpful😍"
United States
Nora
The price is ￥10,160
￥10,160 total
Nov 10 - Nov 11
Donsuites Apart Hotel
A restaurant with tables set for dining, featuring red chairs and a glass partition wall.

12. Rio Arriba Suites Apartments y Resto

Rio Arriba Suites Apartments y Resto
3.5 star property
Bella Vista
8.6 out of 10, Excellent, (4 reviews)
"Pessoal da recepção excelente acolhimento. Hotel bonito, falta manutenção em certos lugares. Quarto ótimo, cama com colchão selado e barulho nos ares condicionados. Café da manhã deixa a desejar. Restaurante muito bonito. "
Brazil
Anonymous traveler
The price is ￥9,306
￥9,306 total
Nov 18 - Nov 19
Rio Arriba Suites Apartments y Resto
A hotel exterior with a stone facade, a well-lit entrance, and a paved area with small trees.

13. Hotel Rio

Hotel Rio
3.0 star property
Chajarí
8.4 out of 10, Very good, (16 reviews)
"Nao vale um centavo"
Brazil
Eduardo
The price is ￥13,598
￥13,598 total
Nov 11 - Nov 12
Hotel Rio
A breakfast buffet with various food items, a coffee machine, and a toaster.

14. Ayres Inn

Ayres Inn
3.0 star property
Federal
The price is ￥10,650
￥10,650 total
Nov 10 - Nov 11
Ayres Inn
A cozy room with a wooden interior, a large window with a view, a chandelier, and a flat-screen TV.

15. La Alondra Casa De Huéspedes

La Alondra Casa De Huéspedes
4.0 star property
Corrientes
9.4 out of 10, Exceptional, (81 reviews)
"a romantic, spacious oasis with lovely old world charm and a delicious breakfast."
United States
Ken
The price is ￥13,720
￥13,720 total
Nov 15 - Nov 16
La Alondra Casa De Huéspedes
Living area

16. Estancia Iberá

Estancia Iberá
3.0 star property
Mercedes
10.0 out of 10, Exceptional, (1 review)
"we had a wonderful experience the staff was very friendly and helpful and took us out on lots of activities and we saw an amazing amount of wildlife in a very short period of time. The place is very beautiful and tranquil. I would highly recommend it and give it five stars. "
Canada
orit
The price is ￥15,686
￥15,686 total
Nov 12 - Nov 13
Estancia Iberá
A hotel room with two beds, a dining table, a vase with flowers, and a large painting on the wall.

17. Hotel Dinastie Palace

Hotel Dinastie Palace
3.0 star property
Chajarí
The price is ￥16,894
￥16,894 total
Nov 10 - Nov 11
Hotel Dinastie Palace
A terrace with a view of a sunset over a body of water, furnished with a sofa, chairs, and a small table.

18. Marriott Corrientes Hotel

Marriott Corrientes Hotel
4.5 star property
Corrientes
9.8 out of 10, Exceptional, (54 reviews)
"👍"
United States
Patricia
The price is ￥22,766
￥22,766 total
Nov 29 - Nov 30
Marriott Corrientes Hotel
A swimming pool with lounge chairs and two thatched-roof structures.

19. Bungalows Mexico

Bungalows Mexico
2.5 star property
Concepción del Uruguay
8.8 out of 10, Excellent, (13 reviews)
"Todo como esperaba. Muy bien. Amables. Lugar en condiciones. "
Argentina
Roberto Alejandro
The price is ￥8,452
￥8,452 total
Nov 13 - Nov 14
Bungalows Mexico
A modern dining area with a glass table, white chairs, a flat-screen TV mounted on a wooden panel, and a plant in the corner.

20. Agustín 1 Apart

Agustín 1 Apart
3.5 star property
Parana
9.2 out of 10, Wonderful, (7 reviews)
"Everything about the place was great. Our only complaint was that the kettle didn't heat water so it was hard to make mate. "
Canada
Patricia
The price is ￥8,130
￥8,130 total
Nov 17 - Nov 18
Agustín 1 Apart
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Hotels recommended for families in Mesopotamia

A covered outdoor swimming pool with lounge chairs and a waterfall feature.

Hathor Concordia

Hathor Concordia
3.0 star property
Concordia
8.8 out of 10, Excellent, (393)
The price is ￥9,135
￥9,135 total
Dec 1 - Dec 2
Hathor Concordia
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Mesopotamia attractions

A dirt path through a dense palm tree forest.

El Palmar National Park

8.0/10 (2 reviews)
Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay.
See properties

Learn more about Mesopotamia

The awe-inspiring Iguazú Falls is the centerpiece attraction of this northeastern Argentine region, which also hosts the country’s biggest carnival celebration.

See all hotels in Mesopotamia
A series of waterfalls surrounded by dense green forest.

Top Mesopotamia Hotel Reviews

Holiday Inn Express Rosario by IHG

Holiday Inn Express Rosario by IHG

10/10 Excellent
"Hermosa estadía en este hotel muy recomendable la atención excelente el desayuno muy bueno la limpieza excelente y todo el personal muy amable y amigable para recomendar"
Jose 8-night trip
Posted 17 hours ago
Holiday Inn Express Rosario by IHG

More cheap stays in Mesopotamia

Como en casa

Como en casa

San Luis 948 8B Rosario Santa Fe
The price is ￥5,388 per night from Nov 18 to Nov 19
￥5,388
￥5,388 total
Nov 18 - Nov 19
8.4/10 Very Good! (7 reviews)

Hotels in Mesopotamia with star-rating