A river winding through a dense forest.

Find hotels in Mesopotamia from ￥4,660

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Oct 15 - Oct 16
Tomorrow
Oct 16 - Oct 17
This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Filter by

Property class

Guest rating

Our top choices for Mesopotamia hotels

A covered outdoor swimming pool with lounge chairs and a waterfall feature.
A modern bathroom with a large bathtub, a view of trees through a window, and a towel rack.
A restaurant with outdoor seating, a pool view, and a bar area with wine glasses.
A breakfast setup with a bowl of fruit, a vase with a plant, a pitcher, a glass of orange juice, and cups of coffee and tea on a table by a window with a view of a balcony and outdoor furniture.

1. Hathor Concordia

Hathor Concordia
Concordia
Australia
Jose
￥9,638
￥11,377 total
Nov 8 - Nov 9
Hathor Concordia
A hotel with a well-lit exterior, a wooden fence, and a garden with various plants and a palm tree.
A breakfast buffet with various food items and beverages.
An outdoor deck with wooden furniture and white umbrellas, overlooking a building with a red roof.
A reception area with a wooden ceiling, a reception desk, two vases with branches, and a table with candles.

2. Club Valle Termal Resort

Club Valle Termal Resort
Federacion
United States
Luis
￥9,860
￥9,860 total
Oct 16 - Oct 17
Club Valle Termal Resort
A hotel with a sign reading "OMARAN SUITES & Towers" at night, illuminated by purple lighting.
A poolside area with lounge chairs and a towel.
An outdoor patio with wicker furniture, a large umbrella, and potted plants.
A spacious lobby with a modern design, featuring a large purple sofa, matching ottomans, and a glass coffee table.

3. Maran Suites & Towers - Hotel & Spa

Maran Suites & Towers - Hotel & Spa
Parana
United States
Michael
￥15,753
￥15,753 total
Oct 17 - Oct 18
Maran Suites & Towers - Hotel & Spa
A pool area with a fountain, palm trees, and a paved walkway.
A bar area with a curved counter, shelves of liquor bottles, and a buffet setup.
A courtyard with a fountain, lounge chairs, and string lights.
A hotel lobby with a reception desk, a staircase, potted plants, and a waterfall feature.

4. Turismo Hotel Casino

Turismo Hotel Casino
Corrientes
United States
Laura
￥16,463
￥16,463 total
Oct 25 - Oct 26
Turismo Hotel Casino
A swimming pool with clear water, surrounded by palm trees and a modern building in the background.
A modern bedroom with a large bed, a glass-enclosed bathtub, and a view of the city through large windows.
Exterior
A hotel room with a large bed, bedside lamps, a nightstand, a desk with a computer, a mirror, and a bathroom with a bathtub.

5. Mayim Hotel Termal & SPA

Mayim Hotel Termal & SPA
Concordia
Costa Rica
Federico
￥13,208
￥13,208 total
Nov 13 - Nov 14
Mayim Hotel Termal & SPA
A spacious lobby with black and red seating, a reception desk, and a staircase connecting two levels.
A neatly made bed with white linens and folded towels, a dark headboard, and a view of greenery through a window.
A modern lounge area with black leather sofas, glass tables, and red chairs.
A hotel room with a large bed, a nightstand, a wall-mounted lamp, and a sliding glass door leading to a balcony.

6. O2 Hotel Gualeguaychú

O2 Hotel Gualeguaychú
Gualeguaychú
United States
Allan
￥7,234
￥7,234 total
Oct 26 - Oct 27
O2 Hotel Gualeguaychú
A large house with a swimming pool surrounded by lush greenery and a river in the background.
A pathway leading to a building surrounded by palm trees and yellow flowers.
A hotel room with a wooden table, two beds, a large window, and a plant.
A resort with multiple swimming pools, lounge areas, and a large house.

7. La Regina Lodge

La Regina Lodge
Municipo de Itati
Brazil
Marcos
￥9,176
￥9,176 total
Nov 2 - Nov 3
La Regina Lodge
Pool
Room
Restaurant
Spa

8. HOTEL TERMAS VICTORIA Wellness Spa

HOTEL TERMAS VICTORIA Wellness Spa
Victoria
Spain
Mariela Emilia
￥19,436
￥19,436 total
Oct 16 - Oct 17
HOTEL TERMAS VICTORIA Wellness Spa
A terrace with a view of a sunset over a body of water, featuring a small island and a row of chairs.
An indoor swimming pool with a covered roof, clear poolside chairs, and a central pool ladder.
A reception area with a curved wooden counter, a staircase in the background, and a framed picture on the wall.
A restaurant with large windows, tables, and chairs.

9. Intersur Colon

Intersur Colon
Colón
United States
Carla
￥14,819
￥14,819 total
Oct 21 - Oct 22
Intersur Colon
An aerial view of a resort with a large swimming pool, multiple buildings, and a parking area.
A spacious living area with a white sofa, a coffee table, and a dining area in the background.
A hotel with a spa, pool, and restaurant.
A hotel room with two beds, a small desk, a television, and a window with a view.

10. Hotel y Spa Termas del Este

Hotel y Spa Termas del Este
Federacion
Canada
Chase
￥8,652
￥8,652 total
Oct 16 - Oct 17
Hotel y Spa Termas del Este
A room with wicker chairs, a wooden table, and a view of a body of water through large windows.
A cocktail in a glass with a lime garnish, set against a blurred background of various bottles.
A multi-story hotel with a modern architectural design, featuring balconies, large windows, and a prominent entrance area.
A conservatory with a panoramic view of a lake, furnished with wicker chairs and a table set for breakfast.

11. Costarenas Hotel & Spa

Costarenas Hotel & Spa
Colon
Argentina
Lisette
￥19,207
￥19,207 total
Oct 16 - Oct 17
Costarenas Hotel & Spa
A swimming pool with steps leading into it, surrounded by lounge chairs and umbrellas, with a building in the background.
A building with a sign reading "La Loma" and a rustic sign with the same name.
A dining area with a table set for two, a painting of a cityscape, and a view of the outside.
A residential area with a swimming pool, lounge chairs, and a well-maintained lawn.

12. Complejo La Loma

Complejo La Loma
Federacion
Canada
Logan
￥5,125
￥5,334 total
Oct 17 - Oct 18
Complejo La Loma
A restaurant with tables set for dining, featuring red chairs and a glass partition wall.
A covered outdoor area with a wooden structure, surrounded by lush greenery and trees.
A living room with a beige sofa, a wooden coffee table with magazines, and a vase of flowers.
A covered outdoor area with a stone pathway leading to a building.

13. Rio Arriba Suites Apartments y Resto

Rio Arriba Suites Apartments y Resto
Bella Vista
Brazil
Anonymous traveler
￥9,603
￥9,603 total
Oct 16 - Oct 17
Rio Arriba Suites Apartments y Resto
A hotel room with two beds, a nightstand, a telephone, and a framed picture on the wall.
A building with a restaurant named 'bahia' and a sign for 'Universidad Siglo 21'.
A breakfast buffet with various food items, a coffee machine, and a toaster.
A modern hotel lobby with a seating area, a reception desk, and a marble floor.

14. Ayres Inn

Ayres Inn
Federal
￥10,623
￥10,623 total
Oct 26 - Oct 27
Ayres Inn
A modern indoor swimming pool with a wooden deck, large windows offering a view of the sea and boats.
Room
A dining area with a table and chairs, a kitchen in the background, and a bathroom visible through an open door.
A rooftop terrace with a wooden deck, outdoor seating, and potted plants.

15. Donsuites Apart Hotel

Donsuites Apart Hotel
Corrientes
United States
Nora
￥10,306
￥10,306 total
Oct 16 - Oct 17
Donsuites Apart Hotel
A hotel exterior with a stone facade, a well-lit entrance, and a paved area with small trees.
A hallway with large windows, a radiator, and red vases.
A poolside setting with a stone wall, a glass of orange juice, a plate with food, and an open book.
A breakfast tray with croissants, juice, and coffee in a bright dining area with white furniture.

16. Hotel Rio

Hotel Rio
Chajarí
Brazil
Eduardo
￥13,563
￥13,563 total
Oct 23 - Oct 24
Hotel Rio
A cozy room with a wooden interior, a large window with a view, a chandelier, and a flat-screen TV.
A rustic interior with exposed brick walls, a wooden floor, and a staircase leading to a balcony.
A multi-level atrium with a staircase, string lights, and potted plants.
A pool area with a long, narrow pool, surrounded by plants and trees. There are outdoor seating areas and a building with large windows in the background.

17. La Alondra Casa De Huéspedes

La Alondra Casa De Huéspedes
Corrientes
United States
Ken
￥11,522
￥11,522 total
Nov 15 - Nov 16
La Alondra Casa De Huéspedes
A terrace with a view of a sunset over a body of water, furnished with a sofa, chairs, and a small table.
A restaurant with a modern interior, featuring leather seating, a bar area with stools, and large windows offering a view of the outdoors.
A modern lobby with a curved sofa, a round coffee table, and a bookshelf filled with decorative items.
A balcony with lounge chairs, a swimming pool, and a view of the sea.

18. Marriott Corrientes Hotel

Marriott Corrientes Hotel
Corrientes
Australia
Marcus
￥22,745
￥22,745 total
Oct 18 - Oct 19
Marriott Corrientes Hotel
A room with a bed, a painting, a table with chairs, and an air conditioning unit.
A modern bedroom with a bed, a dining area with a table, and a kitchen in the background.
A compact kitchen with a microwave, a kettle, and a sink. There is a round table with chairs and a vase with flowers.
A patio with a table and chairs, a grill, and a white wall with decorative panels.

19. Hotel Dinastie Palace

Hotel Dinastie Palace
Chajarí
￥19,728
￥19,728 total
Oct 16 - Oct 17
Hotel Dinastie Palace
A dining area with tables, chairs, a wooden cabinet, and a mirror on the wall.
A bedroom with a bed, a chair, a desk, a shelf with plants, and an air conditioning unit.
A building with a stone facade, a visible entrance, and a sign with a blue 'H' indicating a hotel.
A hallway with a wooden chair, a table, and a potted plant.

20. hotel san lorenzo design

hotel san lorenzo design
Corrientes
United States
Omar
￥6,402
￥6,402 total
Oct 21 - Oct 22
hotel san lorenzo design
View all properties

Vacation Rentals in Mesopotamia

Condo
A hotel with a well-lit exterior, a wooden fence, and a garden with various plants and a palm tree.
A breakfast buffet with various food items and beverages.
An outdoor deck with wooden furniture and white umbrellas, overlooking a building with a red roof.
A reception area with a wooden ceiling, a reception desk, two vases with branches, and a table with candles.

Club Valle Termal Resort

Club Valle Termal Resort
Federacion
"Hh"
Club Valle Termal Resort
Cabin
A swimming pool with lounge chairs and two thatched-roof structures.
A room with a brick wall, a bed with orange bedding, a television mounted on the wall, and a door labeled "SALIDA".
A row of single-story, light-colored mobile homes with small windows and a flat roof. Each unit has a small porch area with a wooden bench.
A cozy living room with a brick wall, a television mounted above a sofa, a wooden table with chairs, and a window with curtains.

Bungalows Mexico

Bungalows Mexico
Concepción del Uruguay
"Todo como esperaba. Muy bien. Amables. Lugar en condiciones. "
Bungalows Mexico
Aparthotel
A swimming pool with steps leading into it, surrounded by lounge chairs and umbrellas, with a building in the background.
A building with a sign reading "La Loma" and a rustic sign with the same name.
A dining area with a table set for two, a painting of a cityscape, and a view of the outside.
A residential area with a swimming pool, lounge chairs, and a well-maintained lawn.

Complejo La Loma

Complejo La Loma
Federacion
"Had a very good experience here. Hosts do not speak English, but were very patient with me as I used Google Translate to communicate. Woman at the desk was very kind. I had arrived late and was able to check in without issue. The suite is great - there is a full bathroom, bedroom and kitchen / dining area. There is a communal pool outside in the courtyard as well with lounge chairs. Breakfast was decent as well. Parking on site. I would stay here again for sure, but would be better for multiple...
Complejo La Loma
Aparthotel
A modern indoor swimming pool with a wooden deck, large windows offering a view of the sea and boats.
Room
A dining area with a table and chairs, a kitchen in the background, and a bathroom visible through an open door.
A rooftop terrace with a wooden deck, outdoor seating, and potted plants.

Donsuites Apart Hotel

Donsuites Apart Hotel
Corrientes
"Loved this place, super clean, and the staff were very nice and helpful😍"
Donsuites Apart Hotel
Aparthotel
A swimming pool with a night-time view of buildings, palm trees, and a staircase.
A modern building with a stone facade, a staircase, and surrounding greenery.
A hotel room with two beds, each with a neatly folded white towel and a tag.
A building with a sign reading 'ANJANA apar' surrounded by greenery and a thatched structure.

Complejo Anjana

Complejo Anjana
Federación
"Nice quiet location in nice neighborhood. Recommend"
Complejo Anjana
See all vacation rentals

Hotels recommended for families in Mesopotamia

A covered outdoor swimming pool with lounge chairs and a waterfall feature.
A modern bathroom with a large bathtub, a view of trees through a window, and a towel rack.
A restaurant with outdoor seating, a pool view, and a bar area with wine glasses.
A breakfast setup with a bowl of fruit, a vase with a plant, a pitcher, a glass of orange juice, and cups of coffee and tea on a table by a window with a view of a balcony and outdoor furniture.

Hathor Concordia

Hathor Concordia
Concordia
￥9,638
￥11,377 total
Nov 8 - Nov 9
Hathor Concordia
A swimming pool with clear water, surrounded by palm trees and a modern building in the background.
A modern bedroom with a large bed, a glass-enclosed bathtub, and a view of the city through large windows.
Exterior
A hotel room with a large bed, bedside lamps, a nightstand, a desk with a computer, a mirror, and a bathroom with a bathtub.

Mayim Hotel Termal & SPA

Mayim Hotel Termal & SPA
Concordia
￥13,208
￥13,208 total
Nov 13 - Nov 14
Mayim Hotel Termal & SPA
A hotel with a well-lit exterior, a wooden fence, and a garden with various plants and a palm tree.
A breakfast buffet with various food items and beverages.
An outdoor deck with wooden furniture and white umbrellas, overlooking a building with a red roof.
A reception area with a wooden ceiling, a reception desk, two vases with branches, and a table with candles.

Club Valle Termal Resort

Club Valle Termal Resort
Federacion
￥9,860
￥9,860 total
Oct 16 - Oct 17
Club Valle Termal Resort
A hotel with a sign reading "OMARAN SUITES & Towers" at night, illuminated by purple lighting.
A poolside area with lounge chairs and a towel.
An outdoor patio with wicker furniture, a large umbrella, and potted plants.
A spacious lobby with a modern design, featuring a large purple sofa, matching ottomans, and a glass coffee table.

Maran Suites & Towers - Hotel & Spa

Maran Suites & Towers - Hotel & Spa
Parana
￥15,753
￥15,753 total
Oct 17 - Oct 18
Maran Suites & Towers - Hotel & Spa
A terrace with a view of a sunset over a body of water, furnished with a sofa, chairs, and a small table.
A restaurant with a modern interior, featuring leather seating, a bar area with stools, and large windows offering a view of the outdoors.
A modern lobby with a curved sofa, a round coffee table, and a bookshelf filled with decorative items.
A balcony with lounge chairs, a swimming pool, and a view of the sea.

Marriott Corrientes Hotel

Marriott Corrientes Hotel
Corrientes
￥22,745
￥22,745 total
Oct 18 - Oct 19
Marriott Corrientes Hotel
A pool area with a fountain, palm trees, and a paved walkway.
A bar area with a curved counter, shelves of liquor bottles, and a buffet setup.
A courtyard with a fountain, lounge chairs, and string lights.
A hotel lobby with a reception desk, a staircase, potted plants, and a waterfall feature.

Turismo Hotel Casino

Turismo Hotel Casino
Corrientes
￥16,463
￥16,463 total
Oct 25 - Oct 26
Turismo Hotel Casino
Outdoor pool
Interior
Interior
Hallway

Posada de la Laguna-lodge

Posada de la Laguna-lodge
Colonia Carlos Pellegrini
￥55,328
￥55,328 total
Oct 16 - Oct 17
Posada de la Laguna-lodge
A large house with a swimming pool surrounded by lush greenery and a river in the background.
A pathway leading to a building surrounded by palm trees and yellow flowers.
A hotel room with a wooden table, two beds, a large window, and a plant.
A resort with multiple swimming pools, lounge areas, and a large house.

La Regina Lodge

La Regina Lodge
Municipo de Itati
￥9,176
￥9,176 total
Nov 2 - Nov 3
La Regina Lodge
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Mesopotamia attractions

A dirt path through a dense palm tree forest.

El Palmar National Park

8.0/10 (2 reviews)
Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay.
See properties
A large church with a prominent dome and two bell towers.

Basilica Nuestra Senora De Itati

Learn about the local history of Municipo de Itatí when you take a trip to Basilica Nuestra Senora De Itati.
See properties
A stone pergola with steps leading up to it, surrounded by greenery and a clear sky.

Costanera de Corrientes

9.0/10 (4 reviews)
Enjoy an outing to Costanera de Corrientes during your stay in Corrientes. You can enjoy the restaurants while in the area.
See properties

Termas de Federacion

10.0/10 (2 reviews)
Bring your family to Termas de Federacion and have a fun-filled day at this amusement park in Federacion. Stroll along the beaches or discover the area's waterfalls.
See properties

Victoria Beach

If a restful vacation is part of your travel plans, Victoria Beach might be the perfect place to seek out during your trip to Victoria. Make some time to visit the monuments while you're in the area.
See properties

Concepción del Uruguay City Racetrack

You can take time to visit Concepción del Uruguay City Racetrack during your travels to Concepción del Uruguay. Experience the area's art scene and museums.
See properties

Portal Carambola

You can take time to visit Portal Carambola during your travels to Concepción. While you're in the area, wander around the parks.
See properties

Termas Concepcion Entrerios

Bring your family to Termas Concepcion Entrerios and enjoy the excitement of this amusement park in Concepción del Uruguay. Experience the area's art scene and museums.
See properties

Learn more about Mesopotamia

The awe-inspiring Iguazú Falls is the centerpiece attraction of this northeastern Argentine region, which also hosts the country’s biggest carnival celebration.

See all hotels in Mesopotamia
A series of waterfalls surrounded by dense green forest.

Top Mesopotamia Hotel Reviews

Holiday Inn Express Rosario by IHG

Holiday Inn Express Rosario by IHG

10/10 Excellent
"El hotel y sus instalaciones son excelentes. Solo sugeriría mejorar el espacio para servirse el desayuno ya que es muy pequeño y cuando hay mucha gente se complica andar transitando con la bandeja y los platos y/o tazas ya servidas. Por todo lo demás no hay nada más para acotar ya que nuestra estadía fue muy buena"
Jose 1-night trip
Posted 2 days ago
Holiday Inn Express Rosario by IHG
Howard Johnson by Wyndham Rosario

Howard Johnson by Wyndham Rosario

10/10 Excellent
"Parking sin entregar llave sería lo ideal"
Mariano 1-night trip
Posted 6 days ago
Howard Johnson by Wyndham Rosario
Dazzler by Wyndham Rosario

Dazzler by Wyndham Rosario

10/10 Excellent
"Very good!"
Ysidora 3-night trip
Posted 7 days ago
Dazzler by Wyndham Rosario
Days Inn by Wyndham Zarate

Days Inn by Wyndham Zarate

10/10 Excellent
"Hotel cómodo para viajeros o familia. Parar ahí es evitar capital federal o ahorrar tiempo de viaje"
Eduardo 1-night trip
Posted 8 days ago
Days Inn by Wyndham Zarate
Hathor Concordia

Hathor Concordia

8/10 Good
"EVERYTHING WAS GOOD"
Jose 1-night trip
Posted 3 weeks ago
Hathor Concordia
Mercure Hotel Rosario

Mercure Hotel Rosario

8/10 Good
"Not what we expected"
Juan 1-night trip
Posted 3 weeks ago
Mercure Hotel Rosario
Club Valle Termal Resort

Club Valle Termal Resort

8/10 Good
"Hh"
Luis 1-night trip
Posted 1 month ago
Club Valle Termal Resort
Turismo Hotel Casino

Turismo Hotel Casino

10/10 Excellent
"."
Anibal 1-night trip
Posted 1 month ago
Turismo Hotel Casino
Marriott Corrientes Hotel

Marriott Corrientes Hotel

10/10 Excellent
"Impecable"
Lau 1-night trip
Posted 2 months ago
Marriott Corrientes Hotel

More cheap stays in Mesopotamia

Hosteria Maryland

Hosteria Maryland

AV. FRANCISCO DE HARO 3569 Posadas
￥4,347
￥4,660 total
Nov 1 - Nov 2
6.8/10 (30 reviews)
Hosteria Maryland
hotel san lorenzo design

hotel san lorenzo design

san lorenzo 1138 Corrientes Corrientes Province
￥6,402
￥6,402 total
Oct 21 - Oct 22
5.2/10 (5 reviews)
hotel san lorenzo design
O2 Hotel Gualeguaychú

O2 Hotel Gualeguaychú

115 3 de Febrero Gualeguaychú Entre Ríos
￥7,234
￥7,234 total
Oct 26 - Oct 27
O2 Hotel Gualeguaychú
Carat Apart Boutique

Carat Apart Boutique

Montevideo 1552 Rosario Santa Fe
￥15,968
￥15,968 total
Oct 26 - Oct 27
9.6/10 Exceptional! (57 reviews)
Carat Apart Boutique
Hotel Casino Rio Uruguay

Hotel Casino Rio Uruguay

RN117 Paso de los Libres Corrientes
Get rates
10/10 Exceptional! (1 review)
Hotel Casino Rio Uruguay
Hotel Aguay

Hotel Aguay

Bernard, 2820 Gualeguaychú, Entre Ríos, Argentina Gualeguaychú Entre Ríos Province
Get ratesHotel Aguay

Hotels in Mesopotamia with star-rating

Explore a world of travel with Expedia