A river winding through a dense forest.

Find hotels in Mesopotamia from ￥4,663

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Oct 21 - Oct 22
Tomorrow
Oct 22 - Oct 23
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Filter by

Property class

Guest rating

Our top choices for Mesopotamia hotels

A covered outdoor swimming pool with lounge chairs and a waterfall feature.
A gym with various exercise equipment, large windows with a view of palm trees and a parking lot.
A modern bathroom with a large bathtub, a view of trees through a window, and a towel rack.
A restaurant with outdoor seating, a pool view, and a bar area with wine glasses.

1. Hathor Concordia

Hathor Concordia
Concordia
Australia
Jose
￥9,684
￥11,425 total
Nov 4 - Nov 5
Hathor Concordia
A hotel with a well-lit exterior, a wooden fence, and a garden with various plants and a palm tree.
An outdoor deck with wooden furniture and white umbrellas, overlooking a building with a red roof.
A reception area with a wooden ceiling, a reception desk, two vases with branches, and a table with candles.
A swimming pool with blue chairs and a building in the background.

2. Club Valle Termal Resort

Club Valle Termal Resort
Federacion
United States
Luis
￥9,872
￥9,872 total
Oct 27 - Oct 28
Club Valle Termal Resort
A pool area with a fountain, palm trees, and a paved walkway.
A bar area with a curved counter, shelves of liquor bottles, and a buffet setup.
A hotel lobby with a reception desk, a staircase, potted plants, and a waterfall feature.
A courtyard with a fountain, lounge chairs, and string lights.

3. Turismo Hotel Casino

Turismo Hotel Casino
Corrientes
United States
Laura
￥15,761
￥15,761 total
Oct 26 - Oct 27
Turismo Hotel Casino
A swimming pool with clear water, surrounded by palm trees and a modern building in the background.
A buffet setup with various food items and beverages, including bread, pastries, and a coffee station.
A modern bedroom with a large bed, a glass-enclosed bathtub, and a view of the city through large windows.
A hotel room with a large bed, bedside lamps, a nightstand, a desk with a computer, a mirror, and a bathroom with a bathtub.

4. Mayim Hotel Termal & SPA

Mayim Hotel Termal & SPA
Concordia
Costa Rica
Federico
￥13,663
￥13,663 total
Nov 19 - Nov 20
Mayim Hotel Termal & SPA
A hotel with a sign reading "OMARAN SUITES & Towers" at night, illuminated by purple lighting.
An outdoor patio with wicker furniture, a large umbrella, and potted plants.
A spa room with three wooden lounge chairs, a wall-mounted wooden art piece, and a large window with a view of greenery.
A poolside area with lounge chairs and a towel.

5. Maran Suites & Towers - Hotel & Spa

Maran Suites & Towers - Hotel & Spa
Parana
United States
Michael
￥16,152
￥16,152 total
Oct 27 - Oct 28
Maran Suites & Towers - Hotel & Spa
A swimming pool with steps leading into it, surrounded by lounge chairs and umbrellas, with a building in the background.
A building with a sign reading "La Loma" and a rustic sign with the same name.
A residential area with a swimming pool, lounge chairs, and a well-maintained lawn.
A dining area with a table set for two, a painting of a cityscape, and a view of the outside.

6. Complejo La Loma

Complejo La Loma
Federacion
Canada
Logan
￥5,102
￥5,310 total
Oct 22 - Oct 23
Complejo La Loma
A large house with a swimming pool surrounded by lush greenery and a river in the background.
A pathway leading to a building surrounded by palm trees and yellow flowers.
A resort with multiple swimming pools, lounge areas, and a large house.
A hotel room with a wooden table, two beds, a large window, and a plant.

7. La Regina Lodge

La Regina Lodge
Municipo de Itati
Brazil
Marcos
￥9,182
￥9,182 total
Oct 27 - Oct 28
La Regina Lodge
Pool
Restaurant
Room
Pool

8. HOTEL TERMAS VICTORIA Wellness Spa

HOTEL TERMAS VICTORIA Wellness Spa
Victoria
Spain
Mariela Emilia
￥19,310
￥19,310 total
Nov 16 - Nov 17
HOTEL TERMAS VICTORIA Wellness Spa
A spacious lobby with black and red seating, a reception desk, and a staircase connecting two levels.
A hotel with multiple floors, balconies, and a sign reading "GUALEGUAYCHÚ".
A hotel room with a large bed, a nightstand, a wall-mounted lamp, and a sliding glass door leading to a balcony.
A modern lounge area with black leather sofas, glass tables, and red chairs.

9. O2 Hotel Gualeguaychú

O2 Hotel Gualeguaychú
Gualeguaychú
United States
Allan
￥6,934
￥6,934 total
Oct 31 - Nov 1
O2 Hotel Gualeguaychú
An aerial view of a resort with a large swimming pool, multiple buildings, and a parking area.
A hotel with a spa, pool, and restaurant.
A hotel room with two beds, a small desk, a television, and a window with a view.
A gym with exercise equipment, a large window, and a poster on the wall.

10. Hotel y Spa Termas del Este

Hotel y Spa Termas del Este
Federacion
Canada
Chase
￥8,663
￥8,663 total
Oct 22 - Oct 23
Hotel y Spa Termas del Este
A room with wicker chairs, a wooden table, and a view of a body of water through large windows.
A swimming pool with a stone wall and potted plants.
A cocktail in a glass with a lime garnish, set against a blurred background of various bottles.
A multi-story hotel with a modern architectural design, featuring balconies, large windows, and a prominent entrance area.

11. Costarenas Hotel & Spa

Costarenas Hotel & Spa
Colon
Argentina
Lisette
￥19,231
￥19,231 total
Oct 31 - Nov 1
Costarenas Hotel & Spa
A terrace with a view of a sunset over a body of water, furnished with a sofa, chairs, and a small table.
A restaurant with a modern interior, featuring leather seating, a bar area with stools, and large windows offering a view of the outdoors.
A balcony with lounge chairs, a swimming pool, and a view of the sea.
A modern lobby with a curved sofa, a round coffee table, and a bookshelf filled with decorative items.

12. Marriott Corrientes Hotel

Marriott Corrientes Hotel
Corrientes
Australia
Marcus
￥24,059
￥24,059 total
Nov 4 - Nov 5
Marriott Corrientes Hotel
A terrace with a view of a sunset over a body of water, featuring a small island and a row of chairs.
A restaurant with large windows, tables, and chairs.
An indoor swimming pool with a covered roof, clear poolside chairs, and a central pool ladder.
A multi-story hotel with a prominent sign reading "InterSur Hotel Colon".

13. Intersur Colon

Intersur Colon
Colón
United States
Carla
￥17,637
￥17,637 total
Nov 15 - Nov 16
Intersur Colon
A hotel room with two beds, a nightstand, a telephone, and a framed picture on the wall.
A modern hotel lobby with a seating area, a reception desk, and a marble floor.
A breakfast buffet with various food items, a coffee machine, and a toaster.
A bathroom with a shower, toilet, bidet, and marble tiles.

14. Ayres Inn

Ayres Inn
Federal
￥10,636
￥10,636 total
Oct 22 - Oct 23
Ayres Inn
A restaurant with tables set for dining, featuring red chairs and a glass partition wall.
A living room with a beige sofa, a wooden coffee table with magazines, and a vase of flowers.
A hotel room with two beds, a wooden headboard, a wicker chair, and a small table.
A covered outdoor area with a wooden structure, surrounded by lush greenery and trees.

15. Rio Arriba Suites Apartments y Resto

Rio Arriba Suites Apartments y Resto
Bella Vista
Brazil
Anonymous traveler
￥9,629
￥9,629 total
Oct 25 - Oct 26
Rio Arriba Suites Apartments y Resto
A hotel exterior with a stone facade, a well-lit entrance, and a paved area with small trees.
A poolside setting with a stone wall, a glass of orange juice, a plate with food, and an open book.
A person sitting on a bed in a hotel room, holding a remote control, with a tray of breakfast items in front of them. A television displaying the Netflix logo is mounted on the wall.
A breakfast tray with croissants, juice, and coffee in a bright dining area with white furniture.

16. Hotel Rio

Hotel Rio
Chajarí
Brazil
Eduardo
￥13,580
￥13,580 total
Nov 8 - Nov 9
Hotel Rio
A cozy room with a wooden interior, a large window with a view, a chandelier, and a flat-screen TV.
A multi-level atrium with a staircase, string lights, and potted plants.
A rustic interior with exposed brick walls, a wooden floor, and a staircase leading to a balcony.
A bar area with a wooden counter, a clock, and shelves with bottles.

17. La Alondra Casa De Huéspedes

La Alondra Casa De Huéspedes
Corrientes
United States
Ken
￥12,967
￥12,967 total
Nov 21 - Nov 22
La Alondra Casa De Huéspedes
A modern bedroom with a bed, a dining area with a table, and a kitchen in the background.
A room with a sofa, a dining table, and a chair. There is a window with curtains.
A bedroom with a large bed, a sofa bed, a nightstand, and a painting on the wall.
An outdoor patio with a grill, a table, and chairs.

18. Hotel Dinastie Palace

Hotel Dinastie Palace
Chajarí
￥19,782
￥19,782 total
Oct 25 - Oct 26
Hotel Dinastie Palace
A modern indoor swimming pool with a wooden deck, large windows offering a view of the sea and boats.
A hotel reception area with a reception desk, a waiting area with a sofa, and a large glass door leading outside.
A dining area with a table and chairs, a kitchen in the background, and a bathroom visible through an open door.
A rooftop terrace with a wooden deck, outdoor seating, and potted plants.

19. Donsuites Apart Hotel

Donsuites Apart Hotel
Corrientes
United States
Nora
￥11,008
￥11,008 total
Oct 24 - Oct 25
Donsuites Apart Hotel
A swimming pool with a night-time view of buildings, palm trees, and a staircase.
A hotel room with two beds, each with a neatly folded white towel and a tag.
A modern building with a stone facade, a staircase, and surrounding greenery.
A building with a sign reading 'ANJANA apar' surrounded by greenery and a thatched structure.

20. Complejo Anjana

Complejo Anjana
Federación
United States
jeff
￥8,297
￥8,297 total
Oct 22 - Oct 23
Complejo Anjana
View all properties

Vacation Rentals in Mesopotamia

Aparthotel
A swimming pool with steps leading into it, surrounded by lounge chairs and umbrellas, with a building in the background.
A building with a sign reading "La Loma" and a rustic sign with the same name.
A residential area with a swimming pool, lounge chairs, and a well-maintained lawn.
A dining area with a table set for two, a painting of a cityscape, and a view of the outside.

Complejo La Loma

Complejo La Loma
Federacion
"Had a very good experience here. Hosts do not speak English, but were very patient with me as I used Google Translate to communicate. Woman at the desk was very kind. I had arrived late and was able to check in without issue. The suite is great - there is a full bathroom, bedroom and kitchen / dining area. There is a communal pool outside in the courtyard as well with lounge chairs. Breakfast was decent as well. Parking on site. I would stay here again for sure, but would be better for multiple...
Complejo La Loma
Cabin
A swimming pool with lounge chairs and two thatched-roof structures.
A cozy living room with a brick wall, a television mounted above a sofa, a wooden table with chairs, and a window with curtains.
A row of single-story, light-colored mobile homes with small windows and a flat roof. Each unit has a small porch area with a wooden bench.
A room with a brick wall, a bed with orange bedding, a television mounted on the wall, and a door labeled "SALIDA".

Bungalows Mexico

Bungalows Mexico
Concepción del Uruguay
"Todo como esperaba. Muy bien. Amables. Lugar en condiciones. "
Bungalows Mexico
Apartment
A modern dining area with a glass table, white chairs, a flat-screen TV mounted on a wooden panel, and a plant in the corner.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A person sitting on a beige sofa with a laptop, a glass coffee table, and a lamp in a well-lit room with a white rug.
A man and a woman standing on a balcony with a city view.

Agustín 1 Apart

Agustín 1 Apart
Parana
"Everything about the place was great. Our only complaint was that the kettle didn't heat water so it was hard to make mate. "
Agustín 1 Apart
Aparthotel
A modern indoor swimming pool with a wooden deck, large windows offering a view of the sea and boats.
A hotel reception area with a reception desk, a waiting area with a sofa, and a large glass door leading outside.
A dining area with a table and chairs, a kitchen in the background, and a bathroom visible through an open door.
A rooftop terrace with a wooden deck, outdoor seating, and potted plants.

Donsuites Apart Hotel

Donsuites Apart Hotel
Corrientes
"Loved this place, super clean, and the staff were very nice and helpful😍"
Donsuites Apart Hotel
Aparthotel
A swimming pool with a night-time view of buildings, palm trees, and a staircase.
A hotel room with two beds, each with a neatly folded white towel and a tag.
A modern building with a stone facade, a staircase, and surrounding greenery.
A building with a sign reading 'ANJANA apar' surrounded by greenery and a thatched structure.

Complejo Anjana

Complejo Anjana
Federación
"Nice quiet location in nice neighborhood. Recommend"
Complejo Anjana
See all vacation rentals

Hotels recommended for families in Mesopotamia

A hotel with a well-lit exterior, a wooden fence, and a garden with various plants and a palm tree.
An outdoor deck with wooden furniture and white umbrellas, overlooking a building with a red roof.
A reception area with a wooden ceiling, a reception desk, two vases with branches, and a table with candles.
A swimming pool with blue chairs and a building in the background.

Club Valle Termal Resort

Club Valle Termal Resort
Federacion
￥9,872
￥9,872 total
Oct 27 - Oct 28
Club Valle Termal Resort
A covered outdoor swimming pool with lounge chairs and a waterfall feature.
A gym with various exercise equipment, large windows with a view of palm trees and a parking lot.
A modern bathroom with a large bathtub, a view of trees through a window, and a towel rack.
A restaurant with outdoor seating, a pool view, and a bar area with wine glasses.

Hathor Concordia

Hathor Concordia
Concordia
￥9,684
￥11,425 total
Nov 4 - Nov 5
Hathor Concordia
A hotel with a sign reading "OMARAN SUITES & Towers" at night, illuminated by purple lighting.
An outdoor patio with wicker furniture, a large umbrella, and potted plants.
A spa room with three wooden lounge chairs, a wall-mounted wooden art piece, and a large window with a view of greenery.
A poolside area with lounge chairs and a towel.

Maran Suites & Towers - Hotel & Spa

Maran Suites & Towers - Hotel & Spa
Parana
￥16,152
￥16,152 total
Oct 27 - Oct 28
Maran Suites & Towers - Hotel & Spa
A swimming pool with clear water, surrounded by palm trees and a modern building in the background.
A buffet setup with various food items and beverages, including bread, pastries, and a coffee station.
A modern bedroom with a large bed, a glass-enclosed bathtub, and a view of the city through large windows.
A hotel room with a large bed, bedside lamps, a nightstand, a desk with a computer, a mirror, and a bathroom with a bathtub.

Mayim Hotel Termal & SPA

Mayim Hotel Termal & SPA
Concordia
￥13,663
￥13,663 total
Nov 19 - Nov 20
Mayim Hotel Termal & SPA
A pool area with a fountain, palm trees, and a paved walkway.
A bar area with a curved counter, shelves of liquor bottles, and a buffet setup.
A hotel lobby with a reception desk, a staircase, potted plants, and a waterfall feature.
A courtyard with a fountain, lounge chairs, and string lights.

Turismo Hotel Casino

Turismo Hotel Casino
Corrientes
￥15,761
￥15,761 total
Oct 26 - Oct 27
Turismo Hotel Casino
A large house with a swimming pool surrounded by lush greenery and a river in the background.
A pathway leading to a building surrounded by palm trees and yellow flowers.
A resort with multiple swimming pools, lounge areas, and a large house.
A hotel room with a wooden table, two beds, a large window, and a plant.

La Regina Lodge

La Regina Lodge
Municipo de Itati
￥9,182
￥9,182 total
Oct 27 - Oct 28
La Regina Lodge
An aerial view of a resort with a large swimming pool, multiple buildings, and a parking area.
A hotel with a spa, pool, and restaurant.
A hotel room with two beds, a small desk, a television, and a window with a view.
A gym with exercise equipment, a large window, and a poster on the wall.

Hotel y Spa Termas del Este

Hotel y Spa Termas del Este
Federacion
￥8,663
￥8,663 total
Oct 22 - Oct 23
Hotel y Spa Termas del Este
A restaurant with tables set for dining, featuring red chairs and a glass partition wall.
A living room with a beige sofa, a wooden coffee table with magazines, and a vase of flowers.
A hotel room with two beds, a wooden headboard, a wicker chair, and a small table.
A covered outdoor area with a wooden structure, surrounded by lush greenery and trees.

Rio Arriba Suites Apartments y Resto

Rio Arriba Suites Apartments y Resto
Bella Vista
￥9,629
￥9,629 total
Oct 25 - Oct 26
Rio Arriba Suites Apartments y Resto
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Mesopotamia attractions

A dirt path through a dense palm tree forest.

El Palmar National Park

8.0/10 (2 reviews)
Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay.
See properties
A stone pergola with steps leading up to it, surrounded by greenery and a clear sky.

Costanera de Corrientes

9.0/10 (4 reviews)
Enjoy an outing to Costanera de Corrientes during your stay in Corrientes. You can enjoy the restaurants while in the area.
See properties
A large church with a prominent dome and two bell towers.

Basilica Nuestra Senora De Itati

Learn about the local history of Municipo de Itatí when you take a trip to Basilica Nuestra Senora De Itati.
See properties

Termas de Federacion

10.0/10 (2 reviews)
Bring your family to Termas de Federacion and have a fun-filled day at this amusement park in Federacion. Stroll along the beaches or discover the area's waterfalls.
See properties

Concepción del Uruguay City Racetrack

You can take time to visit Concepción del Uruguay City Racetrack during your travels to Concepción del Uruguay. Experience the area's art scene and museums.
See properties

Termas Concepcion Entrerios

Bring your family to Termas Concepcion Entrerios and enjoy the excitement of this amusement park in Concepción del Uruguay. Experience the area's art scene and museums.
See properties

Isla Cambacua Beach

8.8/10 (5 reviews)
Why not spend a lazy afternoon at Isla Cambacua Beach during your trip to Concepción del Uruguay? Experience the area's art scene and museums.
See properties

Victoria Beach

If a restful vacation is part of your travel plans, Victoria Beach might be the perfect place to seek out during your trip to Victoria. Make some time to visit the monuments while you're in the area.
See properties

Learn more about Mesopotamia

The awe-inspiring Iguazú Falls is the centerpiece attraction of this northeastern Argentine region, which also hosts the country’s biggest carnival celebration.

See all hotels in Mesopotamia
A series of waterfalls surrounded by dense green forest.

Top Mesopotamia Hotel Reviews

Marriott Corrientes Hotel

Marriott Corrientes Hotel

10/10 Excellent
"2 cosas, faltaban toallas en el baño y otra que no me atendieron para poder pedir otra reserva"
Patricia 1-night trip
Posted 2 days ago
Marriott Corrientes Hotel
Holiday Inn Express Rosario by IHG

Holiday Inn Express Rosario by IHG

10/10 Excellent
"El hotel y sus instalaciones son excelentes. Solo sugeriría mejorar el espacio para servirse el desayuno ya que es muy pequeño y cuando hay mucha gente se complica andar transitando con la bandeja y los platos y/o tazas ya servidas. Por todo lo demás no hay nada más para acotar ya que nuestra estadía fue muy buena"
Jose 1-night trip
Posted 8 days ago
Holiday Inn Express Rosario by IHG
Howard Johnson by Wyndham Rosario

Howard Johnson by Wyndham Rosario

10/10 Excellent
"Parking sin entregar llave sería lo ideal"
Mariano 1-night trip
Posted 11 days ago
Howard Johnson by Wyndham Rosario
Days Inn by Wyndham Zarate

Days Inn by Wyndham Zarate

10/10 Excellent
"Hotel cómodo para viajeros o familia. Parar ahí es evitar capital federal o ahorrar tiempo de viaje"
Eduardo 1-night trip
Posted 2 weeks ago
Days Inn by Wyndham Zarate
Hathor Concordia

Hathor Concordia

8/10 Good
"EVERYTHING WAS GOOD"
Jose 1-night trip
Posted 3 weeks ago
Hathor Concordia
hotel san lorenzo design

hotel san lorenzo design

10/10 Excellent
"Buen hotel, se duerme bien y no se escucha ruido de afuera"
Omar 1-night trip
Posted 1 month ago
hotel san lorenzo design
Mercure Hotel Rosario

Mercure Hotel Rosario

8/10 Good
"Not what we expected"
Juan 1-night trip
Posted 1 month ago
Mercure Hotel Rosario
Esplendor by Wyndham Savoy Rosario

Esplendor by Wyndham Savoy Rosario

10/10 Excellent
"Hotel muy recomendable para disfrutar del centro de Rosario. Bar de moda en la planta baja."
Omar 1-night trip
Posted 1 month ago
Esplendor by Wyndham Savoy Rosario
Club Valle Termal Resort

Club Valle Termal Resort

8/10 Good
"Hh"
Luis 1-night trip
Posted 1 month ago
Club Valle Termal Resort

More cheap stays in Mesopotamia

Hosteria Maryland

Hosteria Maryland

AV. FRANCISCO DE HARO 3569 Posadas
￥4,353
￥4,663 total
Nov 4 - Nov 5
6.8/10 (30 reviews)
Hosteria Maryland
hotel san lorenzo design

hotel san lorenzo design

san lorenzo 1138 Corrientes Corrientes Province
￥6,410
￥6,410 total
Oct 22 - Oct 23
5.4/10 (6 reviews)
hotel san lorenzo design
O2 Hotel Gualeguaychú

O2 Hotel Gualeguaychú

115 3 de Febrero Gualeguaychú Entre Ríos
￥6,934
￥6,934 total
Oct 31 - Nov 1
O2 Hotel Gualeguaychú
Carat Apart Boutique

Carat Apart Boutique

Montevideo 1552 Rosario Santa Fe
￥14,626
￥14,626 total
Oct 27 - Oct 28
9.6/10 Exceptional! (57 reviews)
Carat Apart Boutique
Hotel Casino Rio Uruguay

Hotel Casino Rio Uruguay

RN117 Paso de los Libres Corrientes
Get rates
10/10 Exceptional! (1 review)
Hotel Casino Rio Uruguay
Hotel Aguay

Hotel Aguay

Bernard, 2820 Gualeguaychú, Entre Ríos, Argentina Gualeguaychú Entre Ríos Province
Get ratesHotel Aguay

Hotels in Mesopotamia with star-rating

Explore a world of travel with Expedia