Mesopotamia

Travel Guide
Mesopotamia featuring forest scenes
The awe-inspiring Iguazú Falls is the centerpiece attraction of this northeastern Argentine region, which also hosts the country’s biggest carnival celebration.

A heady mix of ancient history, natural beauty and flamboyant festivals features in Argentina’s hot and humid Mesopotamia region. Be inspired by thundering waterfalls, spot exotic wildlife, experience indigenous traditions and relax at sleepy riverside resorts. Mesopotamia sits sandwiched between two mighty rivers, the Río Paraná and Rió Uruguay, and is covered with subtropical rainforests and wetlands. It includes the provinces of Misiones, Corrientes and Entre Ríos.

Straddling the Río Iguazú in Misiones province, and shared between Argentina and Brazil, is the UNESCO-protected Iguazú National Park. Come here to admire the 275 individual waterfalls that make up the Iguazú Falls. Follow trails to panoramic lookouts, ride on a speedboat beneath a cascade and see wildlife such as toucans and monkeys. Access the Brazilian side of the park via a short drive from the town of Puerto Iguazú.

Tour the towns of Misiones to appreciate the province’s diversity. Find a gemstone mine in Wanda, flower-filled gardens in Montecarlo and colonial architecture in Oberá. Visit 17th-century Jesuit ruins at San Ignacio. Saltos del Moconá, in Parque Provincial Moconá, is another waterfall worth visiting.

Discover a breezy esplanade, graceful architecture and artisan markets, which showcase Guarani culture, in Corrientes city. Spend some time at easy-going river towns, including Itati and Ituzaingó. Be amazed by the craggy, granite ravine of Barrancas del Empedrado and hike amid thick forest in Mburucuya National Park. Go in search of some 350 bird species and the rare maned wolf at Esteros del Iberá wetlands reserve.

Hot springs, fishing trips, pristine reserves and boisterous carnival parties await in Entre Ríos province. Gualeguaychú explodes into color in February with arguably Argentina’s most famous carnival. The powdery, white sand at nearby Ñandubaysal evokes images of a tropical island paradise. Fish for huge dorado in Santa Elena and enjoy the charm of riverfront Colón. Don’t miss the enormous yatay palm trees in El Palmar National Park.

The southern area of Mesopotamia is just a short bus ride from Buenos Aires. You can also fly to Corrientes and Puerto Iguazú and then get around the region via public buses and organized tours.

O2 Hotel Gualeguaychú
O2 Hotel Gualeguaychú
2.5 out of 5
115 3 de Febrero, Gualeguaychú, Entre Ríos
The price is ¥4,864 per night from Apr 8 to Apr 9
¥4,864
per night
Apr 8 - Apr 9
Stay at this hotel in Gualeguaychú. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Popular attractions Gualeguaychú Cathedral and San Martin ...
7.2/10 Good! (31 reviews)
"Newly remodeled. Simple (no TV). Clean. Good A/C. Basic breakfast. Friendly staff. Nice rooms. Wifi was non-existent in the room on the 5th floor (despite the front desk resetting their routers), but great everywhere else. The place is in a nice and safe area with nearby restaurants. It’s not 10 ..."

Reviewed on Feb 12, 2024

O2 Hotel Gualeguaychú
Hathor Concordia
Hathor Concordia
3 out of 5
Ruta Nacional 14-km 264.5, Concordia, Entre Rios
The price is ¥9,940 per night from Apr 2 to Apr 3
¥9,940
per night
Apr 2 - Apr 3
Stay at this 3-star business-friendly hotel in Concordia. Enjoy free breakfast, free WiFi, and room service. Popular attractions Concordia Golf Course and Castillo ...
8.4/10 Very Good! (300 reviews)
"The hotel was very clean and quiet. It was a great stop in between Buenos Aires and Puerto Iguazu!! The restaurant had delicious food and great service and a nice selection of wine and beer. The front desk was very welcoming and answered all questions. Also the room itself was clean and had safety ..."

Reviewed on Mar 14, 2024

Hathor Concordia
Club Valle Termal Resort
Club Valle Termal Resort
3 out of 5
Hnas. Bentancourt esq. Coronel Salas, Federacion, Entre Rios
The price is ¥6,722 per night from Apr 16 to Apr 17
¥6,722
per night
Apr 16 - Apr 17
Stay at this 3-star family-friendly hotel in Federacion. Enjoy free breakfast, free WiFi, and a children's pool. Popular attractions Termas de Federacion and ...
Club Valle Termal Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Agustín 1 Apart
Agustín 1 Apart
3.5 out of 5
130 Gral. Pedro Ferré, Parana, Entre Ríos
Stay at this 3.5-star aparthotel in Parana. Enjoy free WiFi, onsite parking, and onsite spa services. Popular attractions Parana Cathedral and Plaza de Mayo ...
Agustín 1 Apart
Donsuites Apart Hotel
Donsuites Apart Hotel
3 out of 5
La Rioja 442, Corrientes, Corrientes
Stay at this 3-star aparthotel in Corrientes. Enjoy free breakfast, free WiFi, and a rooftop terrace. Popular attractions Museo de Artesanías Tradicionales Folclóricas ...
8.6/10 Excellent! (86 reviews)
"Excellent in general, staff was extremely helpful with me in everything , they are the best"

Reviewed on Mar 18, 2024

Donsuites Apart Hotel
Bungalows Mexico
Bungalows Mexico
2.5 out of 5
Carlos Granillo Posse N 197, Concepción del Uruguay, Entre Rios
Stay at this cabin in Concepción del Uruguay. Enjoy free WiFi, free parking, and a children's pool. Popular attractions Palacio San José and Santa Cándida Palace ...
8.8/10 Excellent! (10 reviews)
Muy buena atencion, limpio y todo funciona !!!
"La atencion Excelente, comodo, accesible, Las fotos parecen un lugar de lujo y no es asi pero el lugar esta bien , limpio y comodo. La tv funciona bien y los Aire acondicionados muy bien. La pileta limpia y no estaba fria."

Reviewed on Nov 4, 2021

Bungalows Mexico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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