Find Business Hotels in Southwestern Virginia, VA

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Check availability on Southwestern Virginia Business Hotels

Tonight
Dec 28 - Dec 29
Tomorrow
Dec 29 - Dec 30
Next weekend
Jan 2 - Jan 4
In two weeks
Jan 9 - Jan 11

Our top choices for Southwestern Virginia business-friendly hotels

Front of property - evening/night
The Bolling Wilson Hotel

The Bolling Wilson Hotel

The Bolling Wilson Hotel
3.0 star property
Wytheville
9.6 out of 10, Exceptional, (784)
"Very nice period hotel with very helpful staff and good restaurant."
United States
David
The price is ￥22,326
￥27,368 total
includes taxes & fees
Jan 1 - Jan 2, 2026
The Bolling Wilson Hotel
Lobby
Comfort Inn & Suites Hillsville I-77

Comfort Inn & Suites Hillsville I-77

Comfort Inn & Suites Hillsville I-77
2.5 star property
Hillsville
9.2 out of 10, Wonderful, (1004)
"Enjoyed our stay. Great property and breakfast."
United States
Elizabeth
The price is ￥13,308
￥15,234 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Comfort Inn & Suites Hillsville I-77
Interior entrance
Travelodge by Wyndham Wytheville

Travelodge by Wyndham Wytheville

Travelodge by Wyndham Wytheville
2.0 star property
Wytheville
8.2 out of 10, Very Good, (1267)
"Good stay"
United States
Casey
The price is ￥9,582
￥11,047 total
includes taxes & fees
Dec 29 - Dec 30
Travelodge by Wyndham Wytheville
Front of property
General Francis Marion Hotel

General Francis Marion Hotel

General Francis Marion Hotel
4.0 star property
Marion
9.4 out of 10, Exceptional, (998)
"Great clean and safe place to stay! "
United States
Grant
The price is ￥15,394
￥17,442 total
includes taxes & fees
Dec 29 - Dec 30
General Francis Marion Hotel
Lobby
The Highlander at Radford, Tapestry Collection by Hilton

The Highlander at Radford, Tapestry Collection by Hilton

The Highlander at Radford, Tapestry Collection by Hilton
3.5 star property
Radford
9.6 out of 10, Exceptional, (778)
"Great stay; friendly staff. "
United States
Brian
The price is ￥12,710
￥14,934 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Highlander at Radford, Tapestry Collection by Hilton
Free on-the-go breakfast
avid hotel Salem by IHG

avid hotel Salem by IHG

avid hotel Salem by IHG
2.5 star property
Salem
9.4 out of 10, Exceptional, (1007)
"Great place to stay!"
United States
James
The price is ￥12,400
￥14,050 total
includes taxes & fees
Dec 31 - Jan 1, 2026
avid hotel Salem by IHG
Deluxe Room | In-room safe, individually decorated, individually furnished, desk
Hotel Floyd

Hotel Floyd

Hotel Floyd
2.0 star property
Floyd
9.6 out of 10, Exceptional, (493)
"Clean room, friendly staff, lovely artwork, short walk to restaurants. "
United States
Kathryn
The price is ￥17,223
￥18,997 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hotel Floyd
Standard Room, 2 Queen Beds, Accessible (Mobility) | In-room safe, desk, iron/ironing board, free cribs/infant beds
Holiday Inn Express and Suites Wytheville by IHG

Holiday Inn Express and Suites Wytheville by IHG

Holiday Inn Express and Suites Wytheville by IHG
2.5 star property
Wytheville
9.2 out of 10, Wonderful, (1001)
"Breakfast was good, room very clean and staff was very nice. Will be staying here again."
United States
Dawn
The price is ￥16,127
￥18,595 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express and Suites Wytheville by IHG
Lounge
Jackson Park Inn, an Ascend Collection Hotel

Jackson Park Inn, an Ascend Collection Hotel

Jackson Park Inn, an Ascend Collection Hotel
2.5 star property
Pulaski
9.4 out of 10, Exceptional, (717)
"Very clean. Beautiful rooms. Overall a great place to stay!"
United States
Martin
The price is ￥15,358
￥17,094 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Jackson Park Inn, an Ascend Collection Hotel
Exterior
Country Inn & Suites by Radisson, Wytheville, VA

Country Inn & Suites by Radisson, Wytheville, VA

Country Inn & Suites by Radisson, Wytheville, VA
3.0 star property
Wytheville
8.4 out of 10, Very Good, (1006)
"Extremely clean rooms. Front desk clerk was very helpful. Fast check in. Rooms were very modern and comfortable. "
United States
Chad
The price is ￥14,107
￥16,266 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Country Inn & Suites by Radisson, Wytheville, VA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southwestern Virginia Hotel Reviews

Country Inn & Suites by Radisson, Roanoke, VA

Country Inn & Suites by Radisson, Roanoke, VA

10/10 Excellent
"The room was great! It was very clean; bed was comfy; staff really nice. Breakfast had decent selection options. The area was well stocked and was kept clean and neat. "
Dorothy 1-night trip
Posted 22 hours ago
Country Inn & Suites by Radisson, Roanoke, VA

Frequently asked questions

How much do business-friendly hotels in Southwestern Virginia cost?
Rates for business hotels in Southwestern Virginia range between ￥11,047 and ￥27,368 per night. Whatever your budget, Expedia is here to help you locate the ideal space for a smooth work trip. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Southwestern Virginia?
That depends on your destination in Southwestern Virginia. Many business travelers to Roanoke recommend Country Inn & Suites by Radisson, Roanoke, VA. This 3-stars property has a swimming pool and hypo-allergenic bedding. Hilton Garden Inn Roanoke is another excellent option if you're attending a conference or working remotely in Roanoke. A terrace and a swimming pool are some of the handy amenities at this 3-stars getaway. When work takes you on the road, you can choose from multiple business-friendly hotels in Southwestern Virginia that have a total average guest review rating of 9.1.
How many business-friendly hotels are there in Southwestern Virginia?
Southwestern Virginia has 145 business-friendly hotels to choose from. Whether you're meeting with clients or simply working remotely, these stays have the amenities you need to be productive.
What are the best cheap business-friendly hotels in Southwestern Virginia?
Keep costs down with Expedia's business-friendly hotels in Southwestern Virginia that start at ￥11,047 a night. A cheaper option in Roanoke is Tru By Hilton Roanoke Hollins. Corporate travelers rate it highly for its many amenities, including WiFi and complimentary breakfast. If you're going to Wytheville, check out Holiday Inn Express and Suites Wytheville, an IHG Hotel. A swimming pool and a spa tub are among the conveniences that make it easy to both work and feel at home here. When it's time to explore Southwestern Virginia, add a few terrific free attractions to your work trip itinerary. Breaks Interstate Park and Cumberland Gap National Historical Park are visitor favorites. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in Southwestern Virginia that are also business friendly?
There sure are. Whether you're searching for a stay in Southwestern Virginia with a conference room or a quiet nook with a strong WiFi connection, con espacio para trabajar Expedia's got you covered. Sleep Inn Tanglewood in Roanoke is a great choice. This 2.5-stars business and family-friendly option comes with all the conveniences you'll need, like complimentary breakfast and housekeeping services. Quality Inn Roanoke Airport is another property in Roanoke where corporate travelers can fulfill their work obligations with the family in tow. Complimentary breakfast and laundry facilities are among the amenities you'll find at this 2.5-stars hotel. You'll discover plenty of things to do and see with your little travelers in Roanoke. Virginia Museum of Transportation and Mill Mountain Zoo deliver a great day out.
Why book your business-friendly hotel in Southwestern Virginia with Expedia?
Expedia is here to help you find an ideal business-friendly hotel for your upcoming work trip. From conference spaces and meeting rooms to gyms and spas, our stays come with all you need to get the job done.
How can I find cheap business-friendly hotels in Southwestern Virginia?
Expedia can help you narrow your search for cheap business-friendly hotels in Southwestern Virginia. Simply head to our "traveler experience" filter and click on "business friendly." This will show you properties with amenities designed to help you work comfortably and effectively, like free WiFi and included breakfast. You can also choose your budget and hotel star rating to keep costs down.
What is there to do in Southwestern Virginia near my business-friendly hotel?
No matter your interests, there are lots of things to put on your to-do list in Southwestern Virginia. If you're visiting Roanoke, swing by Virginia Museum of Transportation, Taubman Museum of Art and Mill Mountain Zoo. Packing your bags for Wytheville? Wohlfahrt Haus Dinner Theatre, Gibboney Rock House Museum and Edith Bolling Wilson Birthplace Museum are top attractions in this city.

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