The Best Hotels Closest to Santo Domingo Square in Cartagena for 2026

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Our top choices for Santo Domingo Square hotels

1. Casa Belle Cartagena Hotel Boutique

San Diego, 0.5 km from Santo Domingo Square

Federico

￥32,868

￥32,868 total

Oct 22 - Oct 23

An indoor corridor with arches, a central column, and a dining area with tables and chairs.

An indoor swimming pool with tiled walls and a wooden floor, surrounded by lush green plants and a white building with wooden window frames.

A spacious hallway with a wooden staircase, a ceiling fan, and a potted plant with red flowers.

A building with a balcony, arched windows, and a door with a wreath.

2. Hotel Quadrifolio

Cartagena Centro, 0.2 km from Santo Domingo Square

Juan Carlos

￥55,537

￥55,537 total

Nov 21 - Nov 22

A spacious indoor area with wicker furniture, a pool, and a brick archway.

A spacious indoor area with wicker furniture, a pool, and potted plants.

A rooftop terrace with a white sofa, wicker chairs, and a pool.

A spacious living room with a large sofa, a coffee table, and a chandelier. There is a large painting on the wall and a potted plant in the corner.

3. Casa La Merced by Mustique

San Diego, 0.3 km from Santo Domingo Square

Harry

￥58,464

￥58,464 total

Oct 26 - Oct 27

A hallway with a stone floor, wooden beams, and a large potted plant.

A hallway with a stone floor, a large potted plant, wall-mounted light fixtures, and a decorative wall piece.

A balcony with a railing, a potted plant, and a building with a tiled roof in the background.

A courtyard with a tiled floor, a small pool, and a balcony with wooden railings.

4. Privado Designer Boutique Hotel

San Diego, 0.5 km from Santo Domingo Square

Katherine

￥20,804

￥20,804 total

Oct 26 - Oct 27

A courtyard with potted plants, a stone fountain, and a wooden balcony.

A courtyard with potted plants, a stone fountain, and a tree.

A hot tub area with a stone floor, surrounded by potted plants and a yellow wall.

A staircase leading to an upper level, with a balcony above. There are potted plants and a table with chairs outside.

5. Casa Baloco

Cartagena Centro, 0.1 km from Santo Domingo Square

Juan

￥106,808

￥106,808 total

Oct 22 - Oct 23

A pool area with stone columns, water features, and outdoor seating.

A hotel room with a large bed, a wooden ceiling, a sliding glass door to a bathroom, and a wall-mounted lamp.

A breakfast buffet with various food items and condiments.

A corridor with wooden doors, a herringbone floor, a staircase, and a stone wall.

6. Palacio del Agua by Faranda Boutique

Cartagena Centro, 0.3 km from Santo Domingo Square

Marycela

￥32,823

￥32,823 total

Oct 23 - Oct 24

A pool area with lounge chairs and a stone wall.

A room with wicker furniture, a chandelier, and a view of palm trees through large windows.

A bar area with wooden chairs, a counter with bottles, and hanging crystal chandeliers.

A dining area with a chandelier, wooden ceiling, and tables set for dining.

7. Hotel Casa San Agustin

Cartagena Centro, 0.3 km from Santo Domingo Square

David

￥96,867

￥96,867 total

Nov 15 - Nov 16

A hotel room with a large bed, a seating area with cushions, a view of a tower, and a balcony with a railing.

A breakfast buffet with various food items and beverages.

A modern living room with a flat-screen TV, sofas, a coffee table, and a large window offering a city view.

A spacious room with a ceiling fan, a large flat-screen TV, a wooden cabinet, a sofa, and a view through large glass doors.

8. Hotel Casa Bianca By Faranda Boutique

Cartagena Walled City, 0.4 km from Santo Domingo Square

"We had an amazing stay! The hotel was clean, comfortable, and had everything we needed. Santiago was absolutely wonderful and made us feel very welcome. The young lady assisting with the breakfast service was also amazing and provided such friendly, helpful service. We took full advantage of the breakfast and pool, and both were great. Overall, we really enjoyed our stay and honestly wish we could pick this hotel up and move it around with us whenever we travel so it would always be available!...

Gesemia

￥24,116

￥24,116 total

Oct 29 - Oct 30

A pool area with a stone wall, hanging plants, and a lantern.

A table set for dining with a candle, glasses, and a hat.

A bedroom with two beds, each with a canopy, and a sofa.

A spacious living room with a sofa set, a coffee table, and a chandelier.

9. Casa De Alba Hotel Boutique

Cartagena Centro, 0.1 km from Santo Domingo Square

Christian

￥34,905

￥34,905 total

Oct 26 - Oct 27

A spiral staircase with a central planter, a small table with a chair, and a railing.

A barista preparing a drink at a counter with a view of an outdoor pool and a staircase.

A wicker swing chair with ropes, a stone pillar, and a seating area with cushions.

10. Casa Carolina Luxury Wellness Hotel

Cartagena Centro, 0.2 km from Santo Domingo Square

Richard David

￥54,523

￥54,523 total

Nov 1 - Nov 2

A swimming pool with a tiled deck, surrounded by lush greenery and a building with a balcony.

A historic building with multiple stories, large windows, and a balcony.

A multi-story building with a classic architectural style, featuring a central entrance with a dark door, multiple windows on each floor, and decorative ironwork.

A spacious indoor courtyard with a central palm tree, surrounded by various plants and a stone staircase leading to an upper level.

11. Cinco Quintas Hotel Boutique

Cartagena Centro, 0.3 km from Santo Domingo Square

Fernando

￥39,393

￥39,393 total

Oct 27 - Oct 28

A cozy living room with a white sofa, a wicker bench, a coffee table with a bowl of nuts, and a large mirror reflecting the room.

A restaurant with a checkered floor, wooden tables, and hanging plants.

A rustic indoor garden with a water feature, brick pathway, and lush greenery.

A pool area with a view of a church tower, surrounded by palm trees and outdoor seating.

12. Amarla Boutique Hotel Cartagena

Cartagena Centro, 0.1 km from Santo Domingo Square

Matt

￥47,195

￥47,195 total

Oct 23 - Oct 24

A rooftop pool area with lounge seating, a pool, and a view of a historic building.

A hotel room with a bed, a television, a wooden wardrobe, and a wicker chair.

An outdoor seating area with a sofa, chairs, and a large umbrella.

13. Sophia Hotel By OxoHotel

Cartagena Centro, 0.3 km from Santo Domingo Square

Anthony

￥43,868

￥43,868 total

Oct 24 - Oct 25

A courtyard with two lounge chairs, a brick wall, and a tiled roof.

A building with a balcony, arched doorways, and flags.

A cozy dining area with a marble table, cushioned chairs, and a chandelier.

A spacious living area with a dining table, chairs, a sofa, and a patterned rug.

14. Hotel Casa del Gobernador

Cartagena Centro, 0.2 km from Santo Domingo Square

Peyton

￥49,210

￥49,210 total

Nov 21 - Nov 22

A swimming pool with clear water, surrounded by lush greenery and flowering plants.

A building with a white facade, wooden window bars, and a sign that reads "Bastion."

A spacious atrium with a central seating area, large windows, and a reflective floor.

A spacious indoor area with a dining table and chairs, a sofa, and a lamp.

15. Bastión Luxury Hotel

San Diego, 0.4 km from Santo Domingo Square

Santiago

￥61,068

￥61,068 total

Oct 29 - Oct 30

A swimming pool with a view of historic buildings, including a church with a dome and bell tower.

A modern bedroom with a large bed, a sofa, and a balcony with plants.

A balcony with pink flowers, a person holding a drink, and buildings in the background.

A modern living room with a white coffee table, two sofas, a dining area with a table and chairs, and a large window with blinds.

16. Casa Claver Loft Boutique Hotel

Cartagena Centro, 0.2 km from Santo Domingo Square

Kevin

￥46,493

￥46,493 total

Oct 27 - Oct 28

A pool area with arched structures and a wooden deck.

A room with a bed, a wooden partition, and a view through a window with shutters.

A street view of yellow buildings with balconies, a visible storefront labeled "FENOMEN," and a clear sky.

A wooden door with glass panels leading to an outdoor area with a stone wall and greenery.

17. Casa Trujillo Cartagena

Cartagena Centro, 0.1 km from Santo Domingo Square

Gina

￥33,613

￥33,613 total

Oct 22 - Oct 23

A pool area with a spiral staircase, lounge chairs, and potted plants.

A restaurant with high arched windows, a chandelier, and neatly set dining tables.

An outdoor patio area with wooden furniture, umbrellas, and a pool.

A spacious living room with two sofas, a wooden coffee table, and a ceiling fan.

18. Casa Pestagua Relais Châteaux

Cartagena Centro, < 0.1 km from Santo Domingo Square

Emil

￥105,256

￥105,256 total

Oct 22 - Oct 23

A dining table with a plate of food, a glass vase with flowers, and a woven placemat.

A room with a stone wall, a sofa, a chair, a table with a candle, and hanging lights.

A person sitting by a window with a laptop and a bowl, overlooking a building and greenery.

19. Casa Noa Colonial Rooms

Cartagena Centro, 0.3 km from Santo Domingo Square

Jose P

￥10,639

￥10,639 total

Oct 24 - Oct 25

A narrow street with buildings on both sides, a clear sky, and a small puddle on the ground.

A pool area with two lounge chairs, surrounded by lush plants and a stone wall.

A restaurant with wicker chairs, round tables, and hanging lights.

A covered outdoor area with a pergola, potted plants, and a view of a church tower.

20. Hotel Casa La Mantilla by Faranda Boutique

Cartagena Centro, < 0.1 km from Santo Domingo Square

Julia

￥21,541

￥21,541 total

Oct 25 - Oct 26

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Compare popular hotels close to Santo Domingo Square

Property	Star rating	Guest rating
Casa Belle Cartagena Hotel Boutique	10.0 Exceptional 11 reviews	View
Hotel Quadrifolio	10.0 Exceptional 170 reviews	View
Casa La Merced by Mustique	10.0 Exceptional 38 reviews	View
Privado Designer Boutique Hotel	9.8 Exceptional 191 reviews	View
Casa Baloco	10.0 Exceptional 10 reviews	View

Top Santo Domingo Square Hotel Reviews

Casa Noa Colonial Rooms

10/10 Excellent

"ubicacion perfecta, buenas condiciones, limpio, excelente estadía"

Osh Hotel Cartagena

10/10 Excellent

"Excellent Hotel. Location is also perfect. This was my second time staying here. The food is also incredible. The hotel is so beautiful, the pool the room. Planning already a 2027 trip."

Terrazas Hotel Boutique

10/10 Excellent

"Espectacular. Tanto en ubicación, su personal muy amable. Quisiera destacar la atención del chef Juan Carlos, Sandra quien nos recibió a nuestra llegada y al señor Ildefonso quien nos ayudó demaisado hasta para programar nuestros tours. En general staff muy amable y servicial. El desayuno muy bueno . El aseo. Feliz de haber elegido Terrazas Hotel Boutique lo recomiendo al 100%"

Hotel Casa San Agustin

10/10 Excellent

"All areas of this hotel are super above any hotel you have experienced. Personal details such cards with your name and an included breakfast that is great. However, the best is its staff which is truly make your stay wonderful."

Bastión Luxury Hotel

8/10 Good

"Great location, great service, they just need to improve the breakfast and the elevator was very slow and not working few times."

Mood Matuna Hotel Cartagena

10/10 Excellent

"The room was very warm and inviting. We booked the suite with private pool. The view was beautiful and even though there was a lot of activity on the street, the room was quiet. We loved that the hotel was walking distance to the walled city and many restaurants and nightlife. The restaurant is under construction so we didn’t take advantage of the food services, but that did not impact our stay. We would stay here again."

Four Seasons Hotel & Residences Cartagena

10/10 Excellent

"The hotel and staff were great."

Soy Local Centro Historico

8/10 Good

"Excelente servicio, limpieza y ubicacion."

GHL Collection Armería Real Hotel

8/10 Good

"The room and property were spotless, and every staff member we met was attentive and kind. Breakfast had plenty of good options, and the pool was well kept with great sun for lounging. The room was a bit dark and the magnifying mirror needed replacing, but those were minor. I loved the clothesline in the bathroom, such a thoughtful touch!"

Other attractions near Santo Domingo Square

Cartagena Cathedral

9.2/10 (3,019 reviews)

After visiting Cartagena Cathedral, make a plan to see the other sights and activities in Cartagena. Amble around the area's beautiful beaches or seek out the local tours.

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Templo de Santo Domingo

Templo de Santo Domingo is just one of the places to see in Cartagena, so why not enjoy the other things to explore during your travels? Stroll along the beautiful beaches or seek out the local tours.

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Botero's Mujer Reclinada

You can learn about the history of Cartagena with a stop at Botero's Mujer Reclinada. Stroll along the beautiful beaches or seek out the local tours.

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Santo Domingo Church and Monastery

After visiting Santo Domingo Church and Monastery, make a plan to see the other sights and activities in Cartagena. Stroll along the beautiful beaches or seek out the local tours.

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Iglesia de Santo Domingo

After visiting Iglesia de Santo Domingo, make a plan to see the other sights and activities in Cartagena. Stroll along the beautiful beaches or seek out the local tours.

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Palace of the Inquisition Cartagena Historical Museum

8.6/10 (69 reviews)

You can browse the exhibits at Palace of the Inquisition Cartagena Historical Museum, a museum with a story of its own, during your trip to Cartagena. Amble around the area's beautiful beaches or seek out the local tours.

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Bolivar Square

9.2/10 (2,207 reviews)

Find out about the history of Cartagena when you spend time at Bolivar Square. Amble around the area's beautiful beaches or seek out the local tours.

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Cathedral of Saint Catherine of Alexandria

After visiting Cathedral of Saint Catherine of Alexandria, make a plan to see the other sights and activities in Cartagena. Discover the area's top-notch restaurants or seek out the local tours.

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Frequently asked questions

What's the area like around Santo Domingo Square?

Santo Domingo Square is located in a historic area of Cartagena known for its beautiful beaches. If you're looking for a convenient place to stay, check out the 1200 hotels and other accommodations you'll find within a mile.

Where is the best place to stay near Santo Domingo Square?

Adjacent to Santo Domingo Square, Hotel Voilá Centro Histórico is one of the top choices for your stay based on our traveler data, and this hotel offers 2 outdoor pools and 2 bars. Other good choices within a short distance include Mood Matuna Hotel Cartagena and Osh Hotel Cartagena.

How many hotels can I expect to find close to Santo Domingo Square?

Expedia has 1200 hotels and other accommodations within a mile from Santo Domingo Square.

If I need to cancel the hotel reservation for my stay near Santo Domingo Square, will I receive a refund?

Yes! The majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the top deals on offer near Santo Domingo Square.

Where can I learn more about changing or cancelling my trip in the area near Santo Domingo Square?

To access more information about picking new dates or cancelling your stay near Santo Domingo Square, go to https://www.expedia.com/service/.

What can I see and do near Santo Domingo Square?

Study the collections at Palace of the Inquisition Cartagena Historical Museum, Palacio de la Inquisicion, or Cartagena's Gold Museum. Plaza Santo Domingo, San Pedro Claver Church and Convent, and Clock Tower are monuments to see when you're exploring the area around Santo Domingo Square. You can wander around Parque de La Marina, Centenary Park, or La Merced Square if you want a dose of fresh air.

Find hotels near Santo Domingo Square, Cartagena from ￥10,639

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Our top choices for Santo Domingo Square hotels

1. Casa Belle Cartagena Hotel Boutique

2. Hotel Quadrifolio

3. Casa La Merced by Mustique

4. Privado Designer Boutique Hotel

5. Casa Baloco

6. Palacio del Agua by Faranda Boutique

7. Hotel Casa San Agustin

8. Hotel Casa Bianca By Faranda Boutique

9. Casa De Alba Hotel Boutique

10. Casa Carolina Luxury Wellness Hotel

11. Cinco Quintas Hotel Boutique

12. Amarla Boutique Hotel Cartagena

13. Sophia Hotel By OxoHotel

14. Hotel Casa del Gobernador

15. Bastión Luxury Hotel

16. Casa Claver Loft Boutique Hotel

17. Casa Trujillo Cartagena

18. Casa Pestagua Relais Châteaux

19. Casa Noa Colonial Rooms

20. Hotel Casa La Mantilla by Faranda Boutique

Compare popular hotels close to Santo Domingo Square

Top Santo Domingo Square Hotel Reviews

Casa Noa Colonial Rooms

Osh Hotel Cartagena

Terrazas Hotel Boutique

Hotel Casa San Agustin

Bastión Luxury Hotel

Mood Matuna Hotel Cartagena

Four Seasons Hotel & Residences Cartagena

Soy Local Centro Historico

GHL Collection Armería Real Hotel

Other attractions near Santo Domingo Square

Cartagena Cathedral

Templo de Santo Domingo

Botero's Mujer Reclinada

Santo Domingo Church and Monastery

Iglesia de Santo Domingo

Palace of the Inquisition Cartagena Historical Museum

Bolivar Square

Cathedral of Saint Catherine of Alexandria

Frequently asked questions