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Compare 418 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Melao Lodge - Boutique Hotel

1.0 star property
9.4 out of 10, Exceptional, (49)
"Remodeled modern, nice"
Melao Lodge - Boutique Hotel

Hyatt Place Manati

3.5 star property
9.4 out of 10, Exceptional, (1011)
"Great place to stay."
The price is ¥23,154
¥30,071 total
includes taxes & fees
Jul 27 - Jul 28
Hyatt Place Manati

Manati Amaizing Studio

3.5 star property
6.0 out of 10, (2)
"The room we had was absolutely horrible. There was an electrical plug dangling next to the shower head and There were missing outlet covers. The communication was awesome and once we told them, they understood why we were not staying there any longer. "
The price is ¥19,771
¥29,751 total
includes taxes & fees
Jul 25 - Jul 26
Manati Amaizing Studio

El Flamingo Beach Club

2.0 star property
7.6 out of 10, Good, (39)
"Was very clean, was able to speak to administration fast regarding the property about entering etc... Very relaxing stay. Would highly recommend "
El Flamingo Beach Club

Puerto Rico Villa Guesthouse

3.0 star property
8.0 out of 10, Very Good, (3)
"Very beautiful "
The price is ¥34,416
¥81,449 total
includes taxes & fees
Jul 28 - Jul 29
Puerto Rico Villa Guesthouse

Casita Linda

2.5 star property
8.0 out of 10, Very Good, (1)
"Angel worked us in on a same-day booking and met with us at 9:00pm for check and was truly a holiday life-saver (thanks to a different VRBO booking never responding on check in). Nice amenities and right next to ocean (more surfing spot rather than swimming, but pool was nice as well). With more times notice and some updates, this place could easily be 5 star. Again, super thanks to Angel for the last-minute accomodations."
The price is ¥25,629
¥36,613 total
includes taxes & fees
Jul 25 - Jul 26
Casita Linda

Casa Colibrí

2.0 star property
4.0 out of 10, (6)
"The first day all the island was black out even with out light the room feels fresh. "
The price is ¥10,796
¥22,212 total
includes taxes & fees
Aug 2 - Aug 3
Casa Colibrí

Casita del Mar Romantic Beach Retreat

2.0 star property
6.0 out of 10, (3)
The price is ¥14,938
¥28,575 total
includes taxes & fees
Jul 29 - Jul 30
Casita del Mar Romantic Beach Retreat

Ventana al Atlantico at Arecibo 681 Ocean Drive

2.5 star property
7.0 out of 10, Good, (229)
"NOTHING like the pictute on Expedia"
The price is ¥15,963
¥22,499 total
includes taxes & fees
Jul 27 - Jul 28
Ventana al Atlantico at Arecibo 681 Ocean Drive

Arecibo Hotel 2104

3.0 star property
7.6 out of 10, Good, (11)
"Convenient, clean, excellent communication throughout. Very happy with our stay!"
Arecibo Hotel 2104

Hatillo

2.0 star property
Hatillo

Vacation Rental Arecibo PR

2.0 star property
9.0 out of 10, Wonderful, (36)
"Nice view, comfortable and very clean."
The price is ¥12,991
¥14,160 total
includes taxes & fees
Jul 28 - Jul 29
Vacation Rental Arecibo PR

BednBong Experience Stay

3.0 star property
9.6 out of 10, Exceptional, (17)
"Great place awesome breakfast"
The price is ¥16,192
¥29,298 total
includes taxes & fees
Jul 27 - Jul 28
BednBong Experience Stay

Parador El Buen Café

3.0 star property
8.4 out of 10, Very Good, (1004)
"The hotel is clean staff is great "
Parador El Buen Café

Hotel El Guajataca

3.5 star property
8.4 out of 10, Very Good, (1004)
"I loved it! Can't wait to come back."
Hotel El Guajataca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santana

Head to sights like Cano Tiburones Nature Reserve as you discover the local area in Santana.

Top Santana Hotel Reviews

Frequently asked questions

Where is the best place for a stay in Santana?

Based on our traveler data, Arecibo Inn is one of the top choices for your stay. This hotel offers 2 outdoor pools and a full-service spa. Other good choices for your stay in the area are Hyatt Place Manati and Hotel El Guajataca. See all available top hotels, or vacation rentals in Santana.

What are some of the best vacation rentals that Santana has to offer?

3-Bedroom House in Quebradillas: This vacation home rental near Santana is located near the airport and has a terrace, a garden, and free WiFi to put you at ease in your new surroundings. This vacation rental also comes with free parking to give you added peace of mind. See all vacation rentals in Santana.

If I need to cancel my hotel reservation in Santana, will I receive a refund?

Yes! You'll find that most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santana.

Where can I learn more about changing or cancelling my trip to Santana?

To access more information about rescheduling or cancelling your trip to Santana, head over to our customer service page.

How is it to stay in Santana?

Visitors are sure to enjoy all that Santana has to offer. In Santana, there are 3 hotels and other accommodations to choose from. Find out more about Santana.

What should I do while I'm visiting Santana?

A favorite place to visit is Cano Tiburones Nature Reserve. You'll also find La Poza Beach and Arecibo Lighthouse in the area. Check out what more to see and do in Expedia's Santana guide.

What's the seasonal weather like in Santana?

The hottest months are usually August and July with an average temp of 81°F, while the coldest months are March and January with an average of 76°F. Average annual precipitation for Santana is 46 inches.