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Compare 220 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Prairie Home hotels

Isle of Capri Casino Hotel Boonville

3.0 star property
8.2 out of 10, Very Good, (858)
"Nice weekend get away,"
The price is ¥11,200
¥14,553 total
includes taxes & fees
Sep 7 - Sep 8
Isle of Capri Casino Hotel Boonville

Baymont by Wyndham Columbia, MO

2.5 star property
8.0 out of 10, Very Good, (456)
"Property was very convenient for my needs, shopping and restaurants."
The price is ¥9,061
¥10,236 total
includes taxes & fees
Oct 1 - Oct 2
Baymont by Wyndham Columbia, MO

Drury Plaza Hotel Columbia East

3.0 star property
9.6 out of 10, Exceptional, (1249)
"It was a wonderful stay "
The price is ¥13,915
¥15,720 total
includes taxes & fees
Sep 30 - Oct 1
Drury Plaza Hotel Columbia East

Country Inn & Suites by Radisson, Columbia, MO

2.5 star property
9.0 out of 10, Wonderful, (1590)
"Nice place to stay "
The price is ¥12,247
¥13,835 total
includes taxes & fees
Sep 28 - Sep 29
Country Inn & Suites by Radisson, Columbia, MO

Wingate by Wyndham - Columbia

3.0 star property
9.0 out of 10, Wonderful, (1164)
"Very nice place to stay"
The price is ¥13,961
¥15,772 total
includes taxes & fees
Sep 11 - Sep 12
Wingate by Wyndham - Columbia

Ramada by Wyndham Columbia

2.5 star property
7.4 out of 10, Good, (1002)
"A very nice, quiet, restful stay"
The price is ¥9,380
¥10,597 total
includes taxes & fees
Sep 11 - Sep 12
Ramada by Wyndham Columbia

The Broadway Columbia - a DoubleTree by Hilton

4.0 star property
9.4 out of 10, Exceptional, (892)
"Great stay!!"
The price is ¥19,128
¥21,706 total
includes taxes & fees
Sep 29 - Sep 30
The Broadway Columbia - a DoubleTree by Hilton

Quality Inn & Suites Columbia I-70

2.5 star property
7.0 out of 10, Good, (706)
"This Quality Inns and Suite has easy access to I70. The prices are great and it's clean and reasonable. This is my 'go to' when staying in Columbia."
The price is ¥9,194
¥10,387 total
includes taxes & fees
Sep 8 - Sep 9
Quality Inn & Suites Columbia I-70

Extended Stay America Select Suites - Columbia - Stadium Blvd.

2.5 star property
7.0 out of 10, Good, (1000)
"Very pet friendly "
The price is ¥11,724
¥13,246 total
includes taxes & fees
Sep 8 - Sep 9
Extended Stay America Select Suites - Columbia - Stadium Blvd.

Comfort Suites Columbia - University Area

2.5 star property
7.8 out of 10, Good, (939)
"Comfortable bed, good breakfast, friendly staff. "
The price is ¥12,402
¥14,012 total
includes taxes & fees
Sep 28 - Sep 29
Comfort Suites Columbia - University Area

Fairfield Inn & Suites by Marriott Columbia

2.5 star property
8.2 out of 10, Very Good, (560)
"Very easy access to rooms "
The price is ¥13,917
¥15,722 total
includes taxes & fees
Sep 28 - Sep 29
Fairfield Inn & Suites by Marriott Columbia

Wyndham Executive Center Columbia

3.5 star property
8.4 out of 10, Very Good, (1000)
"The decor was unique, like an old western hotel."
The price is ¥14,523
¥16,408 total
includes taxes & fees
Sep 7 - Sep 8
Wyndham Executive Center Columbia

Drury Inn & Suites Columbia Stadium Boulevard

3.0 star property
9.4 out of 10, Exceptional, (1001)
"Wonderful hotel with great amenities and a very friendly and helpful staff"
The price is ¥13,915
¥15,720 total
includes taxes & fees
Sep 21 - Sep 22
Drury Inn & Suites Columbia Stadium Boulevard

Staybridge Suites Columbia by IHG

3.0 star property
8.6 out of 10, Excellent, (1000)
"This hotel is good, convenient and safe."
The price is ¥14,361
¥16,224 total
includes taxes & fees
Oct 5 - Oct 6
Staybridge Suites Columbia by IHG

Best Western Plus Columbia Inn

2.5 star property
8.8 out of 10, Excellent, (1180)
"Great stay & price"
The price is ¥10,660
¥12,043 total
includes taxes & fees
Sep 10 - Sep 11
Best Western Plus Columbia Inn

Quality Inn & Suites Boonville - Columbia

2.5 star property
7.4 out of 10, Good, (559)
"Good location and very friendly staff."
The price is ¥13,359
¥15,124 total
includes taxes & fees
Sep 21 - Sep 22
Quality Inn & Suites Boonville - Columbia

Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

2.5 star property
9.0 out of 10, Wonderful, (1013)
"Easy to get to the hotel. "
The price is ¥15,249
¥17,304 total
includes taxes & fees
Sep 28 - Sep 29
Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Hilton Garden Inn Columbia

3.0 star property
8.6 out of 10, Excellent, (508)
"Great stay!! "
The price is ¥18,751
¥21,277 total
includes taxes & fees
Sep 14 - Sep 15
Hilton Garden Inn Columbia

Super 8 by Wyndham Columbia Clark Lane

2.0 star property
6.6 out of 10, (977)
"Nice place"
The price is ¥7,995
¥9,033 total
includes taxes & fees
Sep 7 - Sep 8
Super 8 by Wyndham Columbia Clark Lane

Iron Horse Hotel

3.0 star property
9.6 out of 10, Exceptional, (103)
"We loved our stay at the Iron horse hotel, great rooms lovely people, Nichole made our stay a great one. If we’re ever in the area again we know where we’re gonna stay. Thank you. "
The price is ¥19,098
¥20,669 total
includes taxes & fees
Sep 7 - Sep 8
Iron Horse Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place for a stay in Prairie Home?

Located 15.8 mi (25.4 km) from the heart of Prairie Home, Baymont by Wyndham Columbia, MO is a top choice for your stay based on our traveler data. Other good options for your visit to the area are Wingate by Wyndham - Columbia and Drury Plaza Hotel Columbia East. See all available top hotels, or vacation rentals in Prairie Home.

What's the top vacation rental that Prairie Home has to offer?

Relaxing Three Bedroom Getaway in Boonville: This vacation home rental near Prairie Home has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Prairie Home.

If I need to cancel my hotel reservation in Prairie Home, will I receive a refund?

Yes! Most room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Prairie Home.

Where can I learn more about changing or cancelling my trip to Prairie Home?

For more information about rescheduling or cancelling your trip to Prairie Home, go to https://www.expedia.com/service/.

What's it like staying in Prairie Home?

Those traveling to Prairie Home are sure to enjoy the sights to see and things to do. There are 220 hotels and other accommodations in the surrounding area. Find out more about Prairie Home.

What should I do while I'm visiting Prairie Home?

Places to visit in the wider area include Warm Springs Ranch, Lions Park Aquatic Center, and Boonville Visitors Center and River, Rails & Trails Museum. You'll also find Isle of Capri Casino and Rock Bridge Memorial State Park in the area. Check out what more to see and do in Expedia's Prairie Home guide.

What's the seasonal weather like in Prairie Home?

The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 36°F. Average annual precipitation for Prairie Home is 43 inches.