Prairie Home Vacation Rentals

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Check prices for these dates

In two weeks
Jan 9 - Jan 11
In two months
Feb 20 - Feb 22
In three months
Mar 20 - Mar 22
In four months
Apr 17 - Apr 19

Our top choices for Prairie Home vacation rentals

Outdoor dining
Unique traincar stay at the Katy Caboose!

Unique traincar stay at the Katy Caboose!

Unique traincar stay at the Katy Caboose!
Hartsburg
9.4 out of 10, Exceptional, (10)
"We loved the 3 taverns in town. Great vibe in a tiny town. "
United States
Dusty
The price is ￥15,444
￥27,831 total
includes taxes & fees
Dec 23 - Dec 24
Unique traincar stay at the Katy Caboose!
Fridge, microwave, oven, stovetop
2 Bed 1 Bath Southside Columbia 7 min to Mizzou

2 Bed 1 Bath Southside Columbia 7 min to Mizzou

2 Bed 1 Bath Southside Columbia 7 min to Mizzou
Columbia
10.0 out of 10, Exceptional, (10)
"Nice and clean apartment. Comfortable beds. Great place to stay."
United States
Paul S.
The price is ￥9,465
￥33,285 total
includes taxes & fees
Jan 6 - Jan 7, 2026
2 Bed 1 Bath Southside Columbia 7 min to Mizzou
Fridge, microwave, oven, stovetop
3 Bedroom 1 Bath Pet Friendly 5 min to MU

3 Bedroom 1 Bath Pet Friendly 5 min to MU

3 Bedroom 1 Bath Pet Friendly 5 min to MU
Columbia
10.0 out of 10, Exceptional, (9)
"Very clean and cute home! Great location, close to coffee shops and restaurants. We enjoyed our stay!"
United States
Lori S.
The price is ￥11,831
￥35,651 total
includes taxes & fees
Dec 29 - Dec 30
3 Bedroom 1 Bath Pet Friendly 5 min to MU
Fridge, microwave, oven, stovetop
~A Home Away From Home~Sleeps 8~

~A Home Away From Home~Sleeps 8~

~A Home Away From Home~Sleeps 8~
2.0 star property
Columbia
9.2 out of 10, Wonderful, (5)
"We're going to book again this time next year."
United States
Donna T.
The price is ￥11,989
￥40,469 total
includes taxes & fees
Jan 19 - Jan 20, 2026
~A Home Away From Home~Sleeps 8~
TV
Carriage House by CMU - Upper Condo - Kitchen, King Bed, 65" TV Fast WiFi & AC

Carriage House by CMU - Upper Condo - Kitchen, King Bed, 65" TV Fast WiFi & AC

Carriage House by CMU - Upper Condo - Kitchen, King Bed, 65" TV Fast WiFi & AC
2.0 star property
Fayette
10.0 out of 10, Exceptional, (11)
"This place is conveniently located near the CMU college and was a nice place to stay so I could visit my son. "
United States
Shannon H.
The price is ￥11,216
￥25,207 total
includes taxes & fees
Dec 26 - Dec 27
Carriage House by CMU - Upper Condo - Kitchen, King Bed, 65" TV Fast WiFi & AC
Fridge, microwave, oven, stovetop
Como's Finest- A Home Away From Home- Sleeps 10

Como's Finest- A Home Away From Home- Sleeps 10

Como's Finest- A Home Away From Home- Sleeps 10
Columbia
8.8 out of 10, Excellent, (5)
"Overall out stay was very nice. Pictures make the place look larger but it was nice and we had enough space. There was an issue with the upstairs toilet not flushing but they came to check it out immediately. Very nice people to work with"
United States
Melissa M.
The price is ￥12,778
￥42,252 total
includes taxes & fees
Dec 23 - Dec 24
Como's Finest- A Home Away From Home- Sleeps 10
Fridge, microwave, oven, stovetop
3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena

3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena

3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena
Columbia
8.8 out of 10, Excellent, (5)
"We had a great weekend in Columbia the property was close to everything we needed. Would definitely recommend and stay again "
United States
Jason C.
The price is ￥18,930
￥49,250 total
includes taxes & fees
Jan 8 - Jan 9, 2026
3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena
Exterior
Step Back in Time Near The Missouri River

Step Back in Time Near The Missouri River

Step Back in Time Near The Missouri River
Jamestown
9.8 out of 10, Exceptional, (17)
"It was very beautiful well stocked, and the owner was very mindful and considerate as to what people needed to be well accommodated and comfortable. I like that."
United States
Latonya M.
The price is ￥23,820
￥36,282 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Step Back in Time Near The Missouri River
Exterior
Cozy cabin getaway with hot-tub under stars!

Cozy cabin getaway with hot-tub under stars!

Cozy cabin getaway with hot-tub under stars!
Ashland
9.6 out of 10, Exceptional, (22)
"This cabin was great and the setting was amazing. So peaceful! I would definitely stay here again."
United States
Tom M.
The price is ￥21,296
￥37,387 total
includes taxes & fees
Dec 23 - Dec 24
Cozy cabin getaway with hot-tub under stars!
2 bedrooms, desk, free WiFi, bed sheets
Historic Cozy Apartment 1 Bedroom In Peaceful Boonville

Historic Cozy Apartment 1 Bedroom In Peaceful Boonville

Historic Cozy Apartment 1 Bedroom In Peaceful Boonville
2.0 star property
Boonville
9.2 out of 10, Wonderful, (14)
"Apartment very clean & neat. Convenient location. "
United States
judith s.
The price is ￥14,056
￥32,115 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Historic Cozy Apartment 1 Bedroom In Peaceful Boonville
Outdoor dining
Near University of Missouri | Fitness Center

Near University of Missouri | Fitness Center

Near University of Missouri | Fitness Center
2.0 star property
Columbia
10.0 out of 10, Exceptional, (1)
The price is ￥20,148
￥26,035 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Near University of Missouri | Fitness Center
Pool
Super Close to Mizzou Condo 2 Bed 1 Bath

Super Close to Mizzou Condo 2 Bed 1 Bath

Super Close to Mizzou Condo 2 Bed 1 Bath
Columbia
10.0 out of 10, Exceptional, (8)
"The property was in a very convenient location and the property owner was ver responsive.I would stay again!!"
United States
Carmen H.
The price is ￥8,676
￥31,550 total
includes taxes & fees
Dec 29 - Dec 30
Super Close to Mizzou Condo 2 Bed 1 Bath
Smart TV
3BR/1.5BA Cozy, Affordable Retreat in Columbia, 10-min from Mizzou

3BR/1.5BA Cozy, Affordable Retreat in Columbia, 10-min from Mizzou

3BR/1.5BA Cozy, Affordable Retreat in Columbia, 10-min from Mizzou
Columbia
10.0 out of 10, Exceptional, (27)
"Clean property, quiet area, amenities appeared to be brand new. Host was very responsive and we enjoyed our stay. "
United States
Kevin R.
The price is ￥13,251
￥38,598 total
includes taxes & fees
Jan 15 - Jan 16, 2026
3BR/1.5BA Cozy, Affordable Retreat in Columbia, 10-min from Mizzou
Fridge, microwave, oven, stovetop
Comfy Home~Teal Feel~ Sleeps 8

Comfy Home~Teal Feel~ Sleeps 8

Comfy Home~Teal Feel~ Sleeps 8
Columbia
The price is ￥11,200
￥34,902 total
includes taxes & fees
Dec 23 - Dec 24
Comfy Home~Teal Feel~ Sleeps 8
Private kitchen
Whispering Woods Hideaway ~ Large Home ~ 85 in TV

Whispering Woods Hideaway ~ Large Home ~ 85 in TV

Whispering Woods Hideaway ~ Large Home ~ 85 in TV
2.0 star property
Columbia
10.0 out of 10, Exceptional, (1)
"Clean house. Very responsive"
United States
Gary B.
The price is ￥23,032
￥70,988 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Whispering Woods Hideaway ~ Large Home ~ 85 in TV
Outdoor dining
The Katy Trail Carriage House Rocheport Mo.

The Katy Trail Carriage House Rocheport Mo.

The Katy Trail Carriage House Rocheport Mo.
Rocheport
10.0 out of 10, Exceptional, (17)
"Just the cutest little apartment. It had everything we needed, in walking distance to every destination desired, and extremely clean. Description and photos were captured beautifully and met all our expectations and more. Would highly recommend. "
United States
Elly B.
The price is ￥23,663
￥38,010 total
includes taxes & fees
Dec 29 - Dec 30
The Katy Trail Carriage House Rocheport Mo.
Fridge, microwave, oven, stovetop
Katy Trail Pull Off

Katy Trail Pull Off

Katy Trail Pull Off
Boonville
9.6 out of 10, Exceptional, (99)
"Great home, quiet neighborhood, and comfy beds. Perfect home for our stay and we will stay again. "
United States
Samantha H.
The price is ￥14,907
￥28,024 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Katy Trail Pull Off
Fridge, microwave, oven, stovetop
It's a Gem ! Comfy Hideaway for R & R ~ King Bed !

It's a Gem ! Comfy Hideaway for R & R ~ King Bed !

It's a Gem ! Comfy Hideaway for R & R ~ King Bed !
Columbia
9.8 out of 10, Exceptional, (20)
"Everything was great from check in to check out. "
United States
Jason L.
The price is ￥23,032
￥55,000 total
includes taxes & fees
Jan 20 - Jan 21, 2026
It's a Gem ! Comfy Hideaway for R & R ~ King Bed !
Fridge, microwave, oven, stovetop
Newly Built Home w/ Fresh Design!

Newly Built Home w/ Fresh Design!

Newly Built Home w/ Fresh Design!
Columbia
9.8 out of 10, Exceptional, (22)
"Beautiful home! Easy to get to from downtown Columbia. Not far from highway 70. "
United States
Kathy S.
The price is ￥31,518
￥53,288 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Newly Built Home w/ Fresh Design!
Smart TV
Brand New Modern Downtown Condo designed by award-winning architect!

Brand New Modern Downtown Condo designed by award-winning architect!

Brand New Modern Downtown Condo designed by award-winning architect!
Columbia
10.0 out of 10, Exceptional, (83)
"It was clean and very nice- close to Mizzou campus so very convenient for our stay- will stay again!"
United States
Kristin G.
The price is ￥32,181
￥54,108 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Brand New Modern Downtown Condo designed by award-winning architect!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Prairie Home Hotel Reviews

Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

10/10 Excellent
"Everything was very clean and in working order. A pleasant room."
Teresa 1-night trip
Posted 2 days ago
Baymont by Wyndham Columbia, MO

Find out more about Prairie Home

Search for holiday rentals in Prairie Home on Expedia! You can easily find your home rentals, villas, holiday apartments in Prairie Home using one of the methods below:

  • View our selection of featured holiday rentals in Prairie Home
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Look no further and take a look at our great range of rental properties in Prairie Home!

Frequently asked questions

Can I find a vacation rental in Prairie Home?

Yes, you can find vacation rentals close to well known attractions in Prairie Home, or you can select a secluded option if you're looking for relaxation.

What's the top vacation rental that Prairie Home has to offer?

3BR/1.5BA Cozy, Affordable Retreat in Columbia, 10-min from Mizzou: This vacation home rental near Prairie Home offers a patio, a garden, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms in addition to a kitchen with a fridge and a microwave.

What can I see and do in Prairie Home?

While exploring the area, visit family-friendly sights like Warm Springs Ranch, or get outside and enjoy nature at Shelter Gardens. California Country Club and Isle of Capri Casino are a couple of places you'll find in the larger area.

What are vacation rentals like in Prairie Home?

Vacation rentals are private properties you can stay in for a few days or a quick weekend in Prairie Home. Vacation rentals feature amenities such as hot tubs, fire pits, and patios so you'll feel right at home. If you're concerned about a clean environment, a vacation rental can provide a sense of seclusion away from public hotel elevators and lobbies packed with people while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for a small group gathering.