New Madrid, MO
Travel Guide
Visit New Madrid

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
New Madrid, MO
The price is ¥24,472 per night from Nov 20 to Nov 21
¥24,472
¥44,356 total
Nov 20 - Nov 21
includes taxes & fees
Stay at this vacation home in New Madrid. Enjoy laundry facilities and air conditioning. Popular attractions New Madrid Historical Museum and River Ridge Winery ...

Hampton Inn Sikeston
1240 Commerce Drive, Sikeston, MO
The price is ¥14,561 per night from Dec 7 to Dec 8
¥14,561
¥16,487 total
Dec 7 - Dec 8
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
8.8/10 Excellent! (417 reviews)
We had a great room. It was clean and the staff was friendly and helpful. The only thing that happened was the elevators went out during the night. I would definitely stay there again.
Reviewed on Oct 30, 2025

Fairfield Inn & Suites by Marriott Sikeston
1239 Commerce Drive, Sikeston, MO
The price is ¥15,448 per night from Nov 16 to Nov 17
¥15,448
¥17,491 total
Nov 16 - Nov 17
includes taxes & fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot ...
9.2/10 Wonderful! (28 reviews)
No doubt you will enjoy
Reviewed on Oct 17, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
New Madrid, MO
Stay at this vacation home in New Madrid. Enjoy laundry facilities and air conditioning. Popular attractions New Madrid Historical Museum and River Ridge Winery ...

Duck Hunting, Fishing or Relaxing Family Vacation
Hornbeak
Stay at this vacation home in Hornbeak. Enjoy a garden, laundry facilities, and patios. Popular attractions Willow Towhead and Rat Island are located ...
9.8/10 Exceptional! (214 reviews)
A great place to stay. Charming deck right on the water with massive cypress trees. The house was spacious and spotless. Very well stocked with everything we needed. Would highly recommend!!!
Reviewed on Oct 29, 2025

Charming 3-bedroom house with WiFi, and boat parking in peaceful Tiptonville
Tiptonville
Stay at this vacation home in Tiptonville. Enjoy laundry facilities and air conditioning. Popular attractions Reelfoot Lake State Park and Campbell's Point are ...
8.8/10 Excellent! (5 reviews)
Our stay at this cabin was everything I hoped for and more. My grandchildren enjoyed the big back yard and fire pit for s’mores. The whole place was immaculate , cozy , roomy and perfect for our gathering. The owner was the sweetest lady to deal with and made everything so easy. A perfect weekend ...
Reviewed on Oct 31, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
New Madrid Historical Museum
4/5(12 reviews)
You can study the exhibits at New Madrid Historical Museum, a museum with a storied past, during your travels to New Madrid. Amble around the area's parks or experience its museums.
Hunter-Dawson State Historic Site
3.5/5(7 reviews)
You can browse the exhibits at Hunter-Dawson State Historic Site, a museum with a story of its own, during your travels to New Madrid. Amble around the area's parks or experience its museums.
River Ridge Winery
4.5/5(4 reviews)
You can enjoy a tasting or tour at River Ridge Winery during your travels to New Madrid. Amble around the area's parks or experience its museums.
