The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

louis

￥17,609 total

includes taxes & fees

Nov 22 - Nov 23

A motel sign with neon lights spelling 'MOTEL' and a green banner with 'Starline Motel' text.

2. Starlite Motel

19 km from Mayo Clinic Scottsdale

Virginia

￥15,405 total

includes taxes & fees

Oct 31 - Nov 1

An outdoor patio with two sofas facing a stone fire pit, under a pergola with string lights.

3. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Claudia

￥25,115 total

includes taxes & fees

Nov 22 - Nov 23

A sign for Superior Suites with a weekly rates display, set against a backdrop of a building with a red-tiled roof and palm trees.

4. Superior Suites Phoenix Mesa

19.6 km from Mayo Clinic Scottsdale

Jo

￥10,060 total

includes taxes & fees

Oct 31 - Nov 1

A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.

5. Hyatt Place Phoenix/Mesa

17.8 km from Mayo Clinic Scottsdale

Laura

￥22,880 total

includes taxes & fees

Nov 22 - Nov 23

A hotel room with a bed, desk, chair, television, fireplace, and a dining area.

6. Sonesta ES Suites Scottsdale Paradise Valley

14 km from Mayo Clinic Scottsdale

James

￥19,945 total

includes taxes & fees

Nov 22 - Nov 23

A modern restaurant with high ceilings, pendant lighting, and a mix of seating arrangements including bar stools and tables.

7. Courtyard by Marriott Mesa At Wrigleyville West

19.1 km from Mayo Clinic Scottsdale

Anusha

￥16,754 total

includes taxes & fees

Nov 23 - Nov 24

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

8. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

Marie

￥18,384 total

includes taxes & fees

Nov 1 - Nov 2

A modern kitchen with white cabinets, a dining area with a sofa, and a large potted plant.

9. Scottsdale Parkview Hotel

17.5 km from Mayo Clinic Scottsdale

Jessica

￥14,419 total

includes taxes & fees

Nov 30 - Dec 1

A modern hotel with a brick facade, large windows, and a covered entrance area.

10. Springhill Suites Phoenix Scottsdale Marriott

18.2 km from Mayo Clinic Scottsdale

Lucinda

￥19,673 total

includes taxes & fees

Nov 22 - Nov 23

A hotel pool area with lounge chairs, a hot tub, and a building with balconies.

11. Motel 6 Old town Scottsdale/Fashion Square

Fashion Square, 15.9 km from Mayo Clinic Scottsdale

Justin

￥14,376 total

includes taxes & fees

Nov 18 - Nov 19

A swimming pool with a bridge structure, surrounded by buildings with outdoor seating and a clear sky.

12. Holiday Inn & Suites Scottsdale North - Airpark by IHG

9.7 km from Mayo Clinic Scottsdale

Ally Marie

￥22,820 total

includes taxes & fees

Nov 23 - Nov 24

A lobby with a stone fireplace, wooden beams, and a chandelier.

13. Great Wolf Lodge Arizona

10.2 km from Mayo Clinic Scottsdale

Dejanira

￥29,325 total

includes taxes & fees

Nov 12 - Nov 13

A hotel lobby with a reception desk, seating area, and a large wall mural.

14. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Joseph

￥16,885 total

includes taxes & fees

Nov 1 - Nov 2

A modern outdoor living area with a fire pit, comfortable seating, and a city view at dusk.

15. Sanctuary Camelback Mountain Resort and Spa

16.8 km from Mayo Clinic Scottsdale

Charles

￥110,150 total

includes taxes & fees

Nov 1 - Nov 2

A hotel lobby with a reception desk, seating area, and large windows.

16. The Azure Hotel

19.1 km from Mayo Clinic Scottsdale

Normalyn

￥12,949 total

includes taxes & fees

Nov 8 - Nov 9

A spacious lobby with a modern design, featuring a central seating area with sofas and a coffee table, a reception desk, and a large window offering a view of the outdoors.

17. The Canyon Suites at The Phoenician, Luxury Collection

17.3 km from Mayo Clinic Scottsdale

phil

￥193,642 total

includes taxes & fees

Nov 23 - Nov 24

A modern kitchen with stainless steel appliances, wooden cabinets, and pendant lighting.

18. Staybridge Suites Scottsdale - Talking Stick by IHG

9.7 km from Mayo Clinic Scottsdale

Robert

￥27,504 total

includes taxes & fees

Nov 29 - Nov 30

A spacious lobby with a large seating area, a reception desk, and artwork on the walls.

19. Best Western Plus Scottsdale Thunderbird Suites

Thunderbird Industrial Airpark, 12.1 km from Mayo Clinic Scottsdale

Susan

￥19,481 total

includes taxes & fees

Nov 23 - Nov 24

A spacious living area with a kitchen, modern furniture, and a fireplace.

20. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

￥21,420 total

includes taxes & fees

Nov 2 - Nov 3

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Top Mayo Clinic Scottsdale Hotel Reviews

Inn at Eagle Mountain

10/10 Excellent

"Good location in it’s proximity to Mayo Clinic Scottsdale. Our trip was cut short and the staff kindly waived the cancellation penalty that was supposed to be charged. Nice, comfortable room."

Fountain Park Hotel, BW Signature Collection

10/10 Excellent

"Room was clean and nice. Property is very quiet and was decorated amazingly for Halloween. Front desk staff are friendly and helpful. Pool area is nice and well maintained. Property is within walking distance to lots of amenities. Breakfast is convenient and nice to have available. Would definitely stay again. Was super convenient to the Mayo Clinic which was the reason for the trip. Great place to stay and very reasonable also."

The Oasis Scottsdale - Bentley Award-Winning Resort Home

8/10 Good

"This is a great house - the layout is perfect to give multiple adult groups privacy and well appointed rooms. The master room and bathroom were incredible. Every group of rooms had its own living space. The pool is amazing - it's surrounded by lush landscaping and the house itself and has multiple types of uses - a shallow end, a deep diving platform, and a hot tub. The house needs some TLC though. The hot tub lighting was eroding off and was duct taped (apparently a long time ago) which had come loose so you're sitting in the water and a grungy looking light strip is floating near you. There was a lot of tree trash in the pool that hadn't been cleaned and we didn't notice a skimmer to do it ourselves. A lot of the exterior light fixtures were damaged or in need of maintenance. The interior lighting was a bit dark.I wouldn't let you put this off from renting the house - we had a great time - but these things did take away from the overall experience and if you're paying the premium they are charging, you shouldn't have to deal with them. I was surprised at this because they shouldn't be that expensive to fix."

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Starlite Motel

3. Home2 Suites by Hilton Mesa Longbow, AZ

4. Superior Suites Phoenix Mesa

5. Hyatt Place Phoenix/Mesa

6. Sonesta ES Suites Scottsdale Paradise Valley

7. Courtyard by Marriott Mesa At Wrigleyville West

8. Aiden by Best Western Scottsdale North

9. Scottsdale Parkview Hotel

10. Springhill Suites Phoenix Scottsdale Marriott

11. Motel 6 Old town Scottsdale/Fashion Square

12. Holiday Inn & Suites Scottsdale North - Airpark by IHG

13. Great Wolf Lodge Arizona

14. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

15. Sanctuary Camelback Mountain Resort and Spa

16. The Azure Hotel

17. The Canyon Suites at The Phoenician, Luxury Collection

18. Staybridge Suites Scottsdale - Talking Stick by IHG

19. Best Western Plus Scottsdale Thunderbird Suites

20. Fountain Park Hotel, BW Signature Collection

Top Mayo Clinic Scottsdale Hotel Reviews

Inn at Eagle Mountain

Frequently asked questions

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