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Discover 12,898 Mayo Clinic hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Country Inn & Suites by Radisson, Phoenix Airport, AZ
Exterior

Country Inn & Suites by Radisson, Phoenix Airport, AZ

3.0 star property
8.2 out of 10, Very Good, (2673)
"Excellent hotel"
The price is ￥10,982
￥12,418 total
includes taxes & fees
Sep 10 - Sep 11
Country Inn & Suites by Radisson, Phoenix Airport, AZ
Holiday Inn Express Hotel & Suites Phoenix-Airport by IHG
Free buffet breakfast

Holiday Inn Express Hotel & Suites Phoenix-Airport by IHG

2.5 star property
9.0 out of 10, Wonderful, (1708)
"Good place to stay"
The price is ￥12,532
￥14,170 total
includes taxes & fees
Sep 28 - Sep 29
Holiday Inn Express Hotel & Suites Phoenix-Airport by IHG
Holiday Inn Express & Suites Phoenix - Airport North by IHG
Free daily buffet breakfast

Holiday Inn Express & Suites Phoenix - Airport North by IHG

2.5 star property
9.4 out of 10, Exceptional, (1948)
"Great place to stay."
The price is ￥13,858
￥15,668 total
includes taxes & fees
Sep 28 - Sep 29
Holiday Inn Express & Suites Phoenix - Airport North by IHG
Sonesta Select Scottsdale at Mayo Clinic Campus
Lobby lounge

Sonesta Select Scottsdale at Mayo Clinic Campus

3.0 star property
8.2 out of 10, Very Good, (1004)
"Stayed there before "
The price is ￥12,203
￥13,906 total
includes taxes & fees
Sep 11 - Sep 12
Sonesta Select Scottsdale at Mayo Clinic Campus
Hilton Garden Inn Phoenix Airport North
Lobby

Hilton Garden Inn Phoenix Airport North

3.0 star property
8.6 out of 10, Excellent, (2111)
"very good place"
The price is ￥12,290
￥13,897 total
includes taxes & fees
Sep 21 - Sep 22
Hilton Garden Inn Phoenix Airport North
Hyatt Place Tempe Phoenix Airport
Free daily buffet breakfast

Hyatt Place Tempe Phoenix Airport

3.0 star property
8.8 out of 10, Excellent, (1007)
"Close to the airport, great price and friendly staff"
The price is ￥13,659
￥15,581 total
includes taxes & fees
Sep 14 - Sep 15
Hyatt Place Tempe Phoenix Airport
Crowne Plaza Phoenix Airport - PHX by IHG
Outdoor pool, open 6:00 AM to 10:00 PM, sun loungers

Crowne Plaza Phoenix Airport - PHX by IHG

3.5 star property
8.4 out of 10, Very Good, (1570)
"Great hotel, clean and comfortable."
The price is ￥10,910
￥12,336 total
includes taxes & fees
Sep 21 - Sep 22
Crowne Plaza Phoenix Airport - PHX by IHG
Hyatt Place Phoenix/Mesa
Garden

Hyatt Place Phoenix/Mesa

3.0 star property
9.2 out of 10, Wonderful, (1616)
"We love our stay"
The price is ￥14,912
￥17,039 total
includes taxes & fees
Sep 10 - Sep 11
Hyatt Place Phoenix/Mesa
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
Gazebo

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

3.0 star property
8.8 out of 10, Excellent, (1660)
"Staff very friendly, the rooms were very clean"
The price is ￥12,184
￥13,887 total
includes taxes & fees
Sep 13 - Sep 14
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
Talking Stick Resort
Exterior

Talking Stick Resort

4.0 star property
9.2 out of 10, Wonderful, (3799)
"It was an amazing stay."
The price is ￥18,515
￥25,313 total
includes taxes & fees
Sep 25 - Sep 26
Talking Stick Resort
Wyndham Phoenix Airport/Tempe
Room, 2 Double Beds, Non Smoking, Balcony | Premium bedding, in-room safe, desk, blackout drapes

Wyndham Phoenix Airport/Tempe

3.5 star property
7.8 out of 10, Good, (1918)
"Good place to stay "
The price is ￥12,207
￥13,925 total
includes taxes & fees
Sep 14 - Sep 15
Wyndham Phoenix Airport/Tempe
Rise Uptown Hotel
In-room safe, individually decorated, individually furnished

Rise Uptown Hotel

4.0 star property
9.2 out of 10, Wonderful, (1092)
"Property was super cute and easy to locate, great location and the pool was perfect."
The price is ￥14,643
￥21,391 total
includes taxes & fees
Sep 28 - Sep 29
Rise Uptown Hotel
The Azure Hotel
Reception

The Azure Hotel

2.5 star property
8.8 out of 10, Excellent, (1508)
"Nice and clean local hotel, very well priced and close to downtown mesa. Will be my go to stay when visiting family in Mesa. "
The price is ￥9,288
￥11,352 total
includes taxes & fees
Sep 10 - Sep 11
The Azure Hotel
University Inn Tempe
Suite, 1 Queen Bed with Sofa bed, Non Smoking | 1 bedroom, premium bedding, pillowtop beds, individually decorated

University Inn Tempe

2.5 star property
9.0 out of 10, Wonderful, (873)
"Love the hotel. Love the design on the wall. "
The price is ￥9,554
￥10,899 total
includes taxes & fees
Sep 11 - Sep 12
University Inn Tempe
SureStay Hotel by Best Western Phoenix Airport
Desk, laptop workspace, blackout drapes, iron/ironing board

SureStay Hotel by Best Western Phoenix Airport

2.5 star property
8.4 out of 10, Very Good, (981)
"Great place to stay "
The price is ￥10,172
￥11,502 total
includes taxes & fees
Sep 14 - Sep 15
SureStay Hotel by Best Western Phoenix Airport
Fountain Park Hotel, BW Signature Collection
Reception

Fountain Park Hotel, BW Signature Collection

3.0 star property
8.8 out of 10, Excellent, (1006)
"Great stay and great price"
The price is ￥13,120
￥14,980 total
includes taxes & fees
Sep 14 - Sep 15
Fountain Park Hotel, BW Signature Collection
Inn at Eagle Mountain
Mountain view

Inn at Eagle Mountain

3.5 star property
8.8 out of 10, Excellent, (1007)
"Very nice property and friendly staff"
Inn at Eagle Mountain
SureStay Plus by Best Western Mesa Superstition Springs
Exterior

SureStay Plus by Best Western Mesa Superstition Springs

2.5 star property
8.4 out of 10, Very Good, (1555)
"Excellent hotel and even better staff! "
The price is ￥10,173
￥11,625 total
includes taxes & fees
Sep 10 - Sep 11
SureStay Plus by Best Western Mesa Superstition Springs
Days Inn & Suites by Wyndham Mesa Near Phoenix
Room, 2 Queen Beds, Accessible, Non Smoking | Pillowtop beds, in-room safe, desk, iron/ironing board

Days Inn & Suites by Wyndham Mesa Near Phoenix

3.0 star property
9.0 out of 10, Wonderful, (1796)
"Good place to stay"
The price is ￥9,199
￥10,512 total
includes taxes & fees
Sep 14 - Sep 15
Days Inn & Suites by Wyndham Mesa Near Phoenix
Fairfield Inn & Suites by Marriott Tempe
Outdoor pool, open 6:00 AM to 11:00 PM, free cabanas, sun loungers

Fairfield Inn & Suites by Marriott Tempe

2.5 star property
9.4 out of 10, Exceptional, (243)
"Decent hotel "
The price is ￥11,647
￥13,284 total
includes taxes & fees
Sep 28 - Sep 29
Fairfield Inn & Suites by Marriott Tempe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mayo Clinic

Find the best Mayo Clinic areas and neighborhoods for the activities you enjoy most.
Downtown Phoenix which includes signage and night scenes

Downtown Phoenix

3 out of top 10 points of interest in this area

A true urban neighborhood, Downtown Phoenix boasts major sports venues like Chase Field and Footprint Center, as well as cultural attractions such as the Arizona Science Center and Phoenix Art Museum. Easily accessible via Valley Metro Light Rail, enjoy walkable streets, friendly cafes, and local businesses.

Old Town

Old Town

Old Town is known for its popular shops, and you can see some sights in the area like Scottsdale Waterfront and Western Spirit: Scottsdale's Museum of the West.

Papago Park featuring desert views as well as a small group of people

Camelback East

2 out of top 10 points of interest in this area

Adjacent to Paradise Valley and Scottsdale, Camelback East Village boasts two main cores and sits between Piestewa Peak and Camelback Mountain. Explore the vibrant 24th Street and Camelback Road or 44th Street and Van Buren Street areas.

East Mesa

While you're in East Mesa, take in top sights like Salt River Tubing and jump on the metro at Superstition Springs Transit Center to see more of the city.

Central Scottsdale

1 out of top 10 points of interest in this area

While visiting Central Scottsdale, you might make a stop by sights like Scottsdale Ranch Park and Starfire Golf Club at Scottsdale Country Club.

Top Mayo Clinic Hotel Reviews

Arizona Biltmore, LXR Hotels & Resorts

Arizona Biltmore, LXR Hotels & Resorts

10/10 Excellent
"Robert in dinning room was exceptional."
Frank 1-night trip
Posted 5 days ago
Arizona Biltmore, LXR Hotels & Resorts

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What is Mayo Clinic like?

Travelers will be sure to find plenty to entertain them in Scottsdale's Mayo Clinic neighborhood.

Where is the best place to stay in Mayo Clinic?

Based on Expedia customer reviews, Sonesta Select Scottsdale at Mayo Clinic Campus is the highest ranked property in Mayo Clinic. This hotel offers a restaurant and an outdoor pool.

How many hotels will I be able to find in the Mayo Clinic area?

With 14 Expedia hotels and other accommodations in Mayo Clinic to choose from, this is a good starting point for exploring the greater Scottsdale area.

If I need to cancel my hotel reservation in Mayo Clinic, will I receive a refund?

Yes! Most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in Mayo Clinic.

Where can I learn more about changing or cancelling my trip to Mayo Clinic?

For more information about updating your trip to Mayo Clinic or cancelling it, go to https://www.expedia.com/service/.

What is there to do around this Scottsdale neighborhood?

A few places to visit in the area around Mayo Clinic include Eagle Mountain Golf Course, Golf Club at Eagle Mountain, and SunRidge Canyon Golf Club. Make a stop at Talking Stick Resort Casino and OdySea Aquarium while you're sightseeing around the area.