Luxury Hotels in Santa Cruz from ￥7,828

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Top cities in Santa Cruz

A historic cathedral with two prominent towers, surrounded by urban buildings and palm trees.
Hotels

Santa Cruz

Santa Cruz

Check prices for these dates

Tonight
Nov 4 - Nov 5
Tomorrow
Nov 5 - Nov 6
This weekend
Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15

Our top choices for Santa Cruz luxury hotels

A poolside area with lounge chairs and a palm tree.

1. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Equipetrol
9.0 out of 10, Wonderful, (424 reviews)
  • cleanliness
    Opulent spa retreat provides luxury treatments, poolside relaxation, and fine dining in Santa Cruz's shopping area.
The price is ￥24,023
￥24,023 total
Nov 13 - Nov 14
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Explore a world of travel with Expedia