Photo by PhotoJoy
Luxury Hotels in Panama from ￥28,193
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Panama Luxury Hotels
Our top choices for Panama luxury hotels
9.0 out of 10, Wonderful, (1,003 reviews)
- Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
The price is ￥39,372
￥43,309 total
includes taxes & fees
Jun 19 - Jun 20
9.4 out of 10, Exceptional, (1,001 reviews)
- Art deco elegance meets modern luxury in this Panama City hotel featuring 2 bars, a full-service spa, and an outdoor pool.
The price is ￥36,632
￥40,295 total
includes taxes & fees
Jun 26 - Jun 27
9.0 out of 10, Wonderful, (1,004 reviews)
- Panama City elegance at this Waldorf Astoria hotel with a full-service spa, outdoor pool, and refined dining in two upscale restaurants.
The price is ￥40,478
￥44,527 total
includes taxes & fees
Jun 19 - Jun 20
9.4 out of 10, Exceptional, (745 reviews)
- A colonial gem in Panama City offering luxurious comfort, exquisite dining, and personalized service in a historic district.
The price is ￥41,426
￥45,569 total
includes taxes & fees
Jul 2 - Jul 3
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Sortis Hotel, Spa & Casino, Autograph Collection by MarriottBella Vista
8.8 out of 10, Excellent, (1,003 reviews)
- Indulge in Panama City luxury with an outdoor pool, full-service spa, and casino at this stylish hotel near Via Espana.
The price is ￥30,102
￥33,112 total
includes taxes & fees
Jun 14 - Jun 15
9.0 out of 10, Wonderful, (1,004 reviews)
- Panama City sophistication meets relaxation with an attached winery, poolside dining, and a full-service spa offering couples' treatments.
The price is ￥36,417
￥40,059 total
includes taxes & fees
Jun 7 - Jun 8
8.4 out of 10, Very Good, (1,000 reviews)
- Indulgent pampering awaits at this Beaux Arts Panama City gem with spa, casino, and rooftop bar.
The Buenaventura Golf & Beach Resort Panama, Autograph Collection
The Buenaventura Golf & Beach Resort Panama, Autograph CollectionEl Chiru
9.2 out of 10, Wonderful, (751 reviews)
- Immerse in beachfront opulence with 12 stunning pools, a full-service spa, and private beach access at this Panama golf resort.
The price is ￥31,695
￥34,864 total
includes taxes & fees
Jun 15 - Jun 16
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Panama Hotel Reviews
Hyatt Regency Panama City
10/10 Excellent
Explore a world of travel with Expedia
- Luxury Hotels in Los Angeles
- Guest Houses in Herrera
- Luxury Hotels in Bugaba
- Resorts in Buenaventura
- Cheap Hotels in Santa Catalina
- Cheap Hotels in Nata
- All-Inclusive Hotel Hotels in Rio Hato
- Ranches in Bocas del Toro Province
- Cheap Hotels in Panama City
- Resorts & Hotels with Spas in Panama City
- Resorts in Bugaba
- Luxury Hotels in Coco Key
- Resorts in Narganá
- Hostels in Santiago
- Luxury Hotels in Santa Catalina
- Lodges in La Laguna
- Guna Yala Hotels
- B&B in La Loma
- B&B in Narganá
- Beach Hotels in La Arena
- B&B in Sorá
- Beach Hotels in Bocas del Toro
- All-Inclusive Hotel Hotels in Cambutal
- Hostels in Sorá
- Resorts in La Loma
- Beach Hotels in Rio Hato
- Hotels with Early Check-in in Panama City
- Aparthotels in Los Angeles
- Santa Clara Hotels
- Santiago Hotels
- Beach Hotels in Panama City
- Guest Houses in Sorá
- Cheap Hotels in Frances
- Resorts in Bocas del Toro Province
- Capsule Hotels in Coclé
- Resorts in La Laguna
- Shopping Hotels in Santa Clara
- Ranches in Bugaba
- San Jose Hotels
- Adults Only Resorts & in Panama City
- La Laguna Hotels
- Beach Hotels in Boca Chica
- Luxury Hotels in Río Sereno
- Los Angeles Hotels
- Panamá Province Hotels
- Resorts in Coco Key
- Cheap Hotels in Guna Yala
- Scuba Diving Hotels in Panama City
- Resorts & Hotels with Spas in Bugaba
- Hotels with a Pool in Panama City
- Adults Only Resorts & in Panamá Province
- Historic Hotels in Boca Chica
- Tocumen Hotels
- Boquete Hotels
- All-Inclusive Hotel Hotels in Bugaba
- Luxury Hotels in Buena Vista
- Pet-Friendly Hotels in San Carlos
- Cheap Hotels in Boquete
- Capsule Hotels in Narganá
- Villas in Los Angeles
- Isla Grande Hotels
- Cheap Hotels in Palenque
- B&B in Bugába
- Resorts in San Blas Islands
- San Blas Islands Hotels
- Cheap Hotels in Los Angeles
- Resorts in Isla Grande
- Resorts in Boquete
- Cheap Hotels in La Laguna
- Resorts in Maria Chiquita
- Cheap Hotels in San Carlos
- Resorts in Los Angeles
- Nata Hotels
- Family Hotels in Anton
- Resorts in Bugába
- Business Hotels in Bugaba
- Beach Hotels in Bugaba
- Sorá Hotels
- Hostels in Bocas del Toro Province
- Panama City Hotels
- Adults Only Resorts & in Bocas del Toro Province
- Resorts in Rio Hato
- Aparthotels in Panama City
- Villas in Colón
- Lodges in San Blas Islands
- Aparthotels in Panamá Province
- Hostels in San Blas Islands
- Romantic Hotels in San Jose
- Aparthotels in La Laguna
- Residences in Los Naranjos
- Resorts in Guna Yala
- Resorts in San Juan Bautista
- Luxury Hotels in Panama City
- Hostels in Nata