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Our top choices for Defiance hotels

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by WyndhamFenton
8.0 out of 10, Very Good, (1,268 reviews)
The price is ¥15,582
¥17,995 total
includes taxes & fees
May 14 - May 15

Quality Inn Foristell
Quality Inn ForistellForistell
8.2 out of 10, Very Good, (982 reviews)
The price is ¥13,819
¥15,609 total
includes taxes & fees
May 17 - May 18

Baymont by Wyndham Warrenton
Baymont by Wyndham WarrentonWarrenton
7.6 out of 10, Good, (1,006 reviews)
The price is ¥11,588
¥13,235 total
includes taxes & fees
May 26 - May 27

Best Western Plus Washington Hotel
Best Western Plus Washington HotelWashington
9.2 out of 10, Wonderful, (681 reviews)
The price is ¥20,212
¥23,012 total
includes taxes & fees
May 14 - May 15

Hampton Inn St. Louis Wentzville
Hampton Inn St. Louis WentzvilleWentzville
9.0 out of 10, Wonderful, (702 reviews)
The price is ¥21,183
¥24,244 total
includes taxes & fees
May 25 - May 26

Super 8 by Wyndham Warrenton
Super 8 by Wyndham WarrentonWarrenton
7.4 out of 10, Good, (646 reviews)
The price is ¥8,523
¥9,735 total
includes taxes & fees
May 19 - May 20

Wingate by Wyndham St. Louis/Fenton Route 66
Wingate by Wyndham St. Louis/Fenton Route 66Fenton
7.8 out of 10, Good, (1,213 reviews)
The price is ¥13,318
¥15,381 total
includes taxes & fees
May 12 - May 13

WoodSpring Suites St Peters-OFallon
WoodSpring Suites St Peters-OFallonSt. Peters
8.6 out of 10, Excellent, (107 reviews)
The price is ¥12,184
¥14,425 total
includes taxes & fees
May 25 - May 26

Drury Inn & Suites Southwest St. Louis
Drury Inn & Suites Southwest St. LouisValley Park
9.6 out of 10, Exceptional, (1,015 reviews)
The price is ¥20,053
¥23,459 total
includes taxes & fees
May 18 - May 19

Holiday Inn Express & Suites St Peters by IHG
Holiday Inn Express & Suites St Peters by IHGSt. Peters
9.2 out of 10, Wonderful, (407 reviews)
The price is ¥17,548
¥21,129 total
includes taxes & fees
May 31 - Jun 1

Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology DriveO'Fallon
9.0 out of 10, Wonderful, (1,011 reviews)
The price is ¥12,860
¥15,170 total
includes taxes & fees
May 19 - May 20

Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. PetersSt. Charles
8.0 out of 10, Very Good, (1,009 reviews)
The price is ¥16,574
¥19,047 total
includes taxes & fees
May 25 - May 26

SpringHill Suites by Marriott St. Louis Chesterfield
SpringHill Suites by Marriott St. Louis ChesterfieldChesterfield
9.8 out of 10, Exceptional, (14 reviews)
The price is ¥18,512
¥21,471 total
includes taxes & fees
May 17 - May 18

Best Western Plus Fenton
Best Western Plus FentonFenton
9.2 out of 10, Wonderful, (282 reviews)
The price is ¥15,540
¥17,946 total
includes taxes & fees
May 17 - May 18

Drury Plaza Hotel St. Louis St. Charles
Drury Plaza Hotel St. Louis St. CharlesSt. Charles
9.6 out of 10, Exceptional, (1,008 reviews)
The price is ¥22,717
¥26,336 total
includes taxes & fees
May 25 - May 26

Super 8 by Wyndham Washington
Super 8 by Wyndham WashingtonWashington
8.4 out of 10, Very Good, (722 reviews)
The price is ¥13,537
¥15,411 total
includes taxes & fees
May 24 - May 25

Comfort Suites St Charles - St Louis
Comfort Suites St Charles - St LouisSt. Charles
8.4 out of 10, Very Good, (1,010 reviews)
The price is ¥14,665
¥16,854 total
includes taxes & fees
May 25 - May 26

Fairfield Inn & Suites Wentzville
Fairfield Inn & Suites WentzvilleWentzville
9.0 out of 10, Wonderful, (674 reviews)
The price is ¥20,757
¥23,757 total
includes taxes & fees
May 24 - May 25

Drury Inn & Suites St. Louis St. Peters
Drury Inn & Suites St. Louis St. PetersSt. Peters
9.4 out of 10, Exceptional, (1,009 reviews)
The price is ¥18,643
¥21,430 total
includes taxes & fees
May 25 - May 26

Holiday Inn Express Warrenton by IHG
Holiday Inn Express Warrenton by IHGWarrenton
9.0 out of 10, Wonderful, (538 reviews)
The price is ¥20,995
¥23,983 total
includes taxes & fees
Jun 7 - Jun 8
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Defiance
Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighboring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

Top Defiance Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
10/10 Excellent
More cheap stays in Defiance

Days Inn and Suites by Wyndham St. Louis/Westport Plaza
1970 Craig Rd Maryland Heights MO
The price is ¥10,654 per night from May 18 to May 19
¥10,654
¥12,359 total
May 18 - May 19
includes taxes & fees
4.6/10 (1,006 reviews)
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