A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Apartments in Defiance for Rent

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Check prices for these dates

In two weeks
Sep 18 - Sep 20
In two months
Oct 30 - Nov 1
In three months
Nov 27 - Nov 29
In four months
Dec 25 - Dec 27

Our top choices for Defiance apartments

A heated pool

1. Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
The price is ￥21,830
￥28,874 total
includes taxes & fees
Sep 13 - Sep 14
Great for Business Travelers! Pool + Gym
Interior

2. Stylish1BRStudioCleanQuietandCozy

Stylish1BRStudioCleanQuietandCozy
Saint Charles
10.0 out of 10, Exceptional, (3 reviews)
"Room was very clean with little to no issues at all. Host was super easy to work with and get information from. This spot is within 15-20minutes OR LESS to anything you’d need to do in the ofallon and surrounding areas. I’d book it again if I needed to."
United States
Mike S.
The price is ￥12,345
￥40,069 total
includes taxes & fees
Sep 8 - Sep 9
Stylish1BRStudioCleanQuietandCozy
Exterior detail

3. 2nd Street Loft - Riverview

2nd Street Loft - Riverview
Washington
10.0 out of 10, Exceptional, (16 reviews)
"Beautiful loft! Great location, walking distance to several restaurants on the river . "
United States
Christy D.
The price is ￥13,332
￥27,200 total
includes taxes & fees
Sep 13 - Sep 14
2nd Street Loft - Riverview
Property grounds

4. Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues

Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues
Ballwin
7.8 out of 10, Good, (23 reviews)
"Nice and roomy place! The shower was a little messy when we went but everything else wemt well"
United States
alex h.
The price is ￥10,548
￥22,999 total
includes taxes & fees
Sep 13 - Sep 14
Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues
Exterior

5. 2nd Street -Deck Suite (back entrance)

2nd Street -Deck Suite (back entrance)
Washington
10.0 out of 10, Exceptional, (9 reviews)
"Great comfortable mini apartment style."
United States
Ozzy
The price is ￥14,176
￥29,049 total
includes taxes & fees
Sep 14 - Sep 15
2nd Street -Deck Suite (back entrance)
Interior

6. Otto's Third | River View Loft by Borgia Church

Otto's Third | River View Loft by Borgia Church
Washington
The price is ￥47,409
￥60,494 total
includes taxes & fees
Sep 8 - Sep 9
Otto's Third | River View Loft by Borgia Church
TV

7. Family Friendly w/ Game Room in Quiet Neighborhood

Family Friendly w/ Game Room in Quiet Neighborhood
Wentzville
10.0 out of 10, Exceptional, (2 reviews)
"Nice house for our week in Lake St. Louis area. Accurate description of what you are getting and clean house. Would stay again if we are back in the area"
United States
Campbell W.
The price is ￥33,596
￥73,130 total
includes taxes & fees
Sep 8 - Sep 9
Family Friendly w/ Game Room in Quiet Neighborhood
1 bedroom, WiFi (free)

8. 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed

1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed
Westport
9.6 out of 10, Exceptional, (41 reviews)
"Great spot!"
United States
Anonymous traveler
The price is ￥9,855
￥11,430 total
includes taxes & fees
Sep 14 - Sep 15
1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed
Interior

9. Dog-Friendly 2BR | Walk to Main Street

Dog-Friendly 2BR | Walk to Main Street
Saint Charles
8.0 out of 10, Very Good, (5 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
The price is ￥15,020
￥42,634 total
includes taxes & fees
Sep 9 - Sep 10
Dog-Friendly 2BR | Walk to Main Street
Exterior

10. Historic Main Street Studio | Dog-Friendly

Historic Main Street Studio | Dog-Friendly
St. Charles Historic District
9.2 out of 10, Wonderful, (37 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
The price is ￥13,501
￥32,244 total
includes taxes & fees
Sep 13 - Sep 14
Historic Main Street Studio | Dog-Friendly
1 bedroom, WiFi, bed sheets

11. Walk to Main | Pet-Friendly Yard & Workspace

Walk to Main | Pet-Friendly Yard & Workspace
St. Charles Historic District
10.0 out of 10, Exceptional, (11 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
The price is ￥19,914
￥43,190 total
includes taxes & fees
Sep 9 - Sep 10
Walk to Main | Pet-Friendly Yard & Workspace
TV

12. 6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (3 reviews)
"Excellent"
United States
Scott N.
The price is ￥15,470
￥44,434 total
includes taxes & fees
Sep 8 - Sep 9
6th street 101 - Walk to Main St
Interior

13. Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (68 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
The price is ￥19,548
￥40,659 total
includes taxes & fees
Sep 8 - Sep 9
Amazing Renovated Historic Loft on Main Street
Interior

14. The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (189 reviews)
"It was great! Clean and great communication with host."
United States
Natalie H.
The price is ￥19,548
￥40,659 total
includes taxes & fees
Sep 8 - Sep 9
The Lofts of North Main Street
Coffee/tea maker, fridge, microwave, stovetop

15. Pet-Friendly Duplex | Historic Main

Pet-Friendly Duplex | Historic Main
St. Charles Historic District
10.0 out of 10, Exceptional, (25 reviews)
"Great location"
United States
todd p.
The price is ￥21,095
￥43,148 total
includes taxes & fees
Sep 9 - Sep 10
Pet-Friendly Duplex | Historic Main
Smart TV

16. Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (116 reviews)
"Host was great. The cutest place in the perfect spot! "
United States
Anonymous traveler
The price is ￥19,548
￥40,659 total
includes taxes & fees
Sep 8 - Sep 9
Prime Loft of Main Street
TV

17. The Global Getaway | World-Inspired 2-Bedroom Stay

The Global Getaway | World-Inspired 2-Bedroom Stay
St. Charles Historic District
10.0 out of 10, Exceptional, (1 review)
"Perfect location to Main Street.Hosts were easy to communicate with.No issues with the unit"
United States
Tony M.
The price is ￥17,251
￥46,859 total
includes taxes & fees
Sep 10 - Sep 11
The Global Getaway | World-Inspired 2-Bedroom Stay
TV

18. Historic Main St 2BR | Steps to Shops

Historic Main St 2BR | Steps to Shops
St. Charles Historic District
9.4 out of 10, Exceptional, (42 reviews)
"This property has a nice renovation while keeping a lot of its original character. Very clean and comfortable beds as well. The location couldn’t be better! We really enjoyed our stay."
United States
William O.
The price is ￥17,214
￥59,103 total
includes taxes & fees
Sep 9 - Sep 10
Historic Main St 2BR | Steps to Shops
TV

19. 1st Capitol Mansion - Suite 401

1st Capitol Mansion - Suite 401
St. Charles Historic District
7.4 out of 10, Good, (9 reviews)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
The price is ￥15,470
￥39,825 total
includes taxes & fees
Sep 10 - Sep 11
1st Capitol Mansion - Suite 401
TV

20. Historic Main St 1BR | Walk to Dining & Nightlife

Historic Main St 1BR | Walk to Dining & Nightlife
St. Charles Historic District
9.2 out of 10, Wonderful, (24 reviews)
"Great place, very fun. I’d stay again for sure. "
United States
Michael C.
The price is ￥21,095
￥42,092 total
includes taxes & fees
Sep 10 - Sep 11
Historic Main St 1BR | Walk to Dining & Nightlife
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive

10/10 Excellent
"Good stay, will book there again!"
Cathy 1-night trip
Posted 1 hour ago
Sleep Inn & Suites O'Fallon MO - Technology Drive

Find out more about Defiance

Defiance Apartments information

Number of reviews
589
Accommodation
114 Apartments
Lowest Price
￥11,430
Highest Price
￥73,130

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your stay.
Why choose an apartment versus a traditional hotel?
Often more spacious than a traditional hotel room, an apartment includes a kitchen for convenient home-cooked meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want something in a quieter part of town.
What's a favorite apartment for a stay in Defiance?
Here are some of the top apartments in the area: 2 Queen Beds | Non-Smoking, Kitchen: Situated in Maryland Heights, 18.7 mi/30.1 km from the heart of Defiance. Includes free WiFi and Smart TVs. The Lofts of North Main Street: Located 19.2 mi/30.8 km away in St. Charles. Free WiFi, sofa beds, and Smart TVs are included. Access to onsite laundry facilities is available on site. Driftwood Den | Boho 2BR | Dog-Friendly: It's situated in St. Charles, 19 mi/30.6 km away. Includes free WiFi. Historic Main St 2BR | Steps to Shops: Located 19.2 mi/30.9 km away in St. Charles. Free WiFi and outdoor space are included. Access to onsite laundry facilities is available on site. Prime Loft of Main Street: Located in St. Charles, 19.2 mi/30.9 km from Defiance. Includes free WiFi, sofa beds, and Smart TVs. Access to onsite laundry facilities is available on site.
How many apartments will I be able to find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather during my trip to Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you're planning an extended stay in Defiance. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Chandler Hill Vineyards and Sugar Creek Winery are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can save you time when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. You can also search for flights into St. Louis Lambert Intl. Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, you may want a rental car for your journey.