Photo by Jessica King

Find hotels in De Soto, MO from ¥8,797

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Compare 171 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Super 8 by Wyndham Farmington
2.0 star property
8.0 out of 10, Very Good, (598)
"Clean, friendly staff, quiet"
United States
Stacy
The price is ¥7,796
¥8,876 total
includes taxes & fees
Nov 3 - Nov 4
Super 8 by Wyndham Farmington
Super 8 by Wyndham Potosi
2.0 star property
7.0 out of 10, Good, (371)
"The room was very good for the price."
United States
Benjamin
The price is ¥8,055
¥8,797 total
includes taxes & fees
Oct 28 - Oct 29
Super 8 by Wyndham Potosi
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
2.5 star property
9.4 out of 10, Exceptional, (688)
"Great place to stay!"
United States
Tracy
The price is ¥19,413
¥22,199 total
includes taxes & fees
Nov 2 - Nov 3
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Pear Tree Inn St. Louis Arnold
2.5 star property
9.2 out of 10, Wonderful, (1002)
"Great stay"
United States
Michelle
The price is ¥13,756
¥15,901 total
includes taxes & fees
Nov 2 - Nov 3
Pear Tree Inn St. Louis Arnold
Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
8.0 out of 10, Very Good, (1010)
"Great location"
United States
Gregory
The price is ¥8,560
¥9,747 total
includes taxes & fees
Nov 3 - Nov 4
Baymont Inn and Suites by Wyndham Farmington, MO
Comfort Inn Festus - St Louis South
2.5 star property
7.8 out of 10, Good, (896)
"The stay and food "
United States
Ricky
The price is ¥12,214
¥14,272 total
includes taxes & fees
Nov 2 - Nov 3
Comfort Inn Festus - St Louis South
Super 8 by Wyndham Bonne Terre
2.0 star property
7.0 out of 10, Good, (525)
"Very nice facility. Room was clean and quiet."
United States
Jeffrey K.
The price is ¥8,316
¥9,094 total
includes taxes & fees
Nov 23 - Nov 24
Super 8 by Wyndham Bonne Terre
Baymont by Wyndham Festus
3.0 star property
6.8 out of 10, (905)
"I really don't want to give them a lousy review because they are trying to do repairs on the building. Beds were comfy, breakfast was good, tv works, and a nice shower!"
United States
Sherry
The price is ¥12,382
¥14,160 total
includes taxes & fees
Oct 30 - Oct 31
Baymont by Wyndham Festus
Quality Inn Farmington
2.5 star property
7.6 out of 10, Good, (848)
"We loved it and we are still staying "
United States
Dustin
The price is ¥8,082
¥9,638 total
includes taxes & fees
Nov 23 - Nov 24
Quality Inn Farmington
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
3.0 star property
8.0 out of 10, Very Good, (870)
"breakfast was good "
United States
Nelvin
The price is ¥14,942
¥17,087 total
includes taxes & fees
Nov 2 - Nov 3
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Crown Pointe Lodge, BW Signature Collection
2.5 star property
9.0 out of 10, Wonderful, (557)
"We'd stay here again."
United States
Russell
The price is ¥15,133
¥17,228 total
includes taxes & fees
Nov 4 - Nov 5
Crown Pointe Lodge, BW Signature Collection
Corner George Inn Bed & Breakfast
2.5 star property
9.0 out of 10, Wonderful, (154)
"Hosts were excellent, very quiet and the breakfast was wonderful"
United States
Mark
The price is ¥18,482
¥20,511 total
includes taxes & fees
Nov 8 - Nov 9
Corner George Inn Bed & Breakfast
WoodSpring Suites St. Louis Arnold
2.5 star property
6.0 out of 10, (430)
"Great location and great price. "
United States
Randall
The price is ¥12,380
¥14,310 total
includes taxes & fees
Oct 30 - Oct 31
WoodSpring Suites St. Louis Arnold
The Conner House B&B
3.5 star property
10.0 out of 10, Exceptional, (18)
"We stayed in the Mississippi suite with the balcony! We enjoyed Connie’s hospitality and the kindness of the staff! We learned about the house itself and history of the area also! "
United States
tiffany
The price is ¥21,497
¥23,857 total
includes taxes & fees
Nov 8 - Nov 9
The Conner House B&B
Hampton Inn Farmington
2.5 star property
8.8 out of 10, Excellent, (509)
"Had a very nice stay!"
United States
Deborah
The price is ¥17,423
¥19,835 total
includes taxes & fees
Nov 2 - Nov 3
Hampton Inn Farmington
Holiday Inn Express & Suites Farmington by IHG
2.5 star property
8.6 out of 10, Excellent, (410)
"Great hotel"
United States
Carole
The price is ¥14,366
¥40,683 total
includes taxes & fees
Nov 16 - Nov 17
Holiday Inn Express & Suites Farmington by IHG
Drury Inn & Suites St. Louis Arnold
3.0 star property
9.6 out of 10, Exceptional, (1004)
"ALWAYS ENJOY OUR STAY HERE TO SEE THE GRAND KIDS"
United States
JULIE
The price is ¥18,800
¥21,732 total
includes taxes & fees
Nov 2 - Nov 3
Drury Inn & Suites St. Louis Arnold
Tiny Houses of French Village
2.5 star property
10.0 out of 10, Exceptional, (3)
"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."
United States
Norma
Tiny Houses of French Village
YMCA Trout Lodge
2.0 star property
The price is ¥25,356
¥27,188 total
includes taxes & fees
Oct 29 - Oct 30
YMCA Trout Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Get away to De Soto! Enjoy the local cuisine and more.

Kayaking down the Big River on a fall day!
Photo by Jessica King
Open Photo by Jessica King

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Frequently asked questions

Where is the best place to stay in De Soto?
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG is one of the top choices for your stay based on our traveler data. This aparthotel offers free parking and private balconies. 82 Acre Hobby Farm with Lincoln Log Cabin is another good choice for your trip. See all available top hotels, or vacation rentals in De Soto.
What are some of the best vacation rentals that De Soto has to offer?
Freshly updated bungalow near Kimmswick and major highways- Prime Location: This vacation home near De Soto is located in the city center and has a patio, a barbecue grill, and air-conditioning to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a stovetop, and a microwave. See all vacation rentals in De Soto.
If I need to cancel my hotel reservation in De Soto, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in De Soto.
Where can I learn more about changing or cancelling my trip to De Soto?
For additional details about picking new dates or cancelling your trip to De Soto, go to https://www.expedia.com/service/.
What's the best pet-friendly hotel in De Soto?
What are some accommodations with pools in De Soto?
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG: Features 2 outdoor tennis courts, a seasonal outdoor pool, and a sauna. Pool, Lake & Patio: Sweeping De Soto Estate and Baymont Inn and Suites by Wyndham Farmington, MO are a couple of other choices with an onsite pool. View all hotels with pools in De Soto.
What is the best accommodation for staying close to Lambert-St. Louis International Airport (STL)?
Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.
What is staying in De Soto like?
Visitors can enjoy all that De Soto has to offer including its restaurants. In De Soto, there are 8 hotels and other accommodations to choose from. Find out more about De Soto.
What should I do while I'm visiting De Soto?
Natural beauty is on display at Sunrise Lake Beach, Big River, and Victoria Glaces Conservation Area Trailhead. A couple of additional sights to add to your agenda are Washington State Park and Big Lake. Check out what more to see and do in Expedia's De Soto guide.
What's the seasonal weather like in De Soto?
The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for De Soto is 46 inches.

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