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Our top choices for Cape Girardeau vacation homes

1. Little Blue Cottage on Spanish
Little Blue Cottage on SpanishCape Girardeau
8.4 out of 10, Very good, (59 reviews)
The price is ¥12,799
¥15,823 total
includes taxes & fees
Nov 15 - Nov 16

2. Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals
Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & HospitalsCape Girardeau
The price is ¥16,496
¥27,495 total
includes taxes & fees
Nov 16 - Nov 17

3. The Little Château | Woodland Escape
The Little Château | Woodland EscapeCape Girardeau
The price is ¥24,531
¥34,312 total
includes taxes & fees
Nov 24 - Nov 25

4. Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
Romantic Creekside Retreat | Fireplace | Deck | Pet FriendlyCape Girardeau
10.0 out of 10, Exceptional, (3 reviews)
The price is ¥24,531
¥32,890 total
includes taxes & fees
Nov 16 - Nov 17

5. The Little Cape Lofted Cottage | Creek & Nature
The Little Cape Lofted Cottage | Creek & NatureCape Girardeau
9.0 out of 10, Wonderful, (2 reviews)
The price is ¥25,440
¥35,273 total
includes taxes & fees
Nov 24 - Nov 25

6. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer PoolCape Girardeau
8.8 out of 10, Excellent, (46 reviews)
The price is ¥28,300
¥47,438 total
includes taxes & fees
Nov 11 - Nov 12

7. Beautifully Renovated Farmhouse in Jackson, MO
Beautifully Renovated Farmhouse in Jackson, MOJackson
9.4 out of 10, Exceptional, (3 reviews)
The price is ¥31,696
¥46,910 total
includes taxes & fees
Nov 11 - Nov 12

8. 4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + MoreCape Girardeau
9.8 out of 10, Exceptional, (11 reviews)
The price is ¥56,910
¥87,768 total
includes taxes & fees
Nov 15 - Nov 16

9. Cozy and Updated Farmhouse with King Suite
Cozy and Updated Farmhouse with King SuiteAnna
10.0 out of 10, Exceptional, (30 reviews)
The price is ¥15,785
¥25,438 total
includes taxes & fees
Nov 16 - Nov 17

10. Stunning 2 bedroom in town, close to Shawnee National Forest
Stunning 2 bedroom in town, close to Shawnee National ForestJonesboro
10.0 out of 10, Exceptional, (15 reviews)
The price is ¥21,807
¥43,099 total
includes taxes & fees
Nov 11 - Nov 12

11. The Weber Farm - Enjoy a beautiful 100 acre farm!
The Weber Farm - Enjoy a beautiful 100 acre farm!Frohna
10.0 out of 10, Exceptional, (34 reviews)
The price is ¥20,541
¥31,847 total
includes taxes & fees
Dec 1 - Dec 2

12. Magical Victorian near hiking / wine trail
Magical Victorian near hiking / wine trailAnna
10.0 out of 10, Exceptional, (21 reviews)
The price is ¥28,064
¥52,710 total
includes taxes & fees
Nov 11 - Nov 12

13. Peach Tree Inn, downtown Cobden
Peach Tree Inn, downtown CobdenCobden
10.0 out of 10, Exceptional, (3 reviews)
The price is ¥29,463
¥35,287 total
includes taxes & fees
Nov 16 - Nov 17

14. Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.
Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.Anna
10.0 out of 10, Exceptional, (16 reviews)
The price is ¥19,625
¥40,895 total
includes taxes & fees
Nov 16 - Nov 17

15. Beautiful location in the secluded woods
Beautiful location in the secluded woodsPomona
9.8 out of 10, Exceptional, (86 reviews)
The price is ¥15,311
¥26,609 total
includes taxes & fees
Nov 30 - Dec 1

16. Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass
Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto PassAlto Pass
10.0 out of 10, Exceptional, (5 reviews)
The price is ¥27,652
¥39,451 total
includes taxes & fees
Nov 24 - Nov 25

17. Peaceful, Comfy and Pet Friendly 2-bedroom home in Quiet Makanda
Peaceful, Comfy and Pet Friendly 2-bedroom home in Quiet MakandaMakanda
10.0 out of 10, Exceptional, (1 review)
The price is ¥17,065
¥20,096 total
includes taxes & fees
Nov 17 - Nov 18

18. Farm Fresh Eggs, Golf Cart, Telescope
Farm Fresh Eggs, Golf Cart, TelescopeAlto Pass
9.8 out of 10, Exceptional, (16 reviews)
The price is ¥34,211
¥39,699 total
includes taxes & fees
Nov 29 - Nov 30

19. King Suite, Hot Tub, walk to Iron Whisk
King Suite, Hot Tub, walk to Iron WhiskCobden
10.0 out of 10, Exceptional, (1 review)
The price is ¥29,463
¥35,287 total
includes taxes & fees
Nov 16 - Nov 17

20. King Suite, Hot Tubs, Cobden
King Suite, Hot Tubs, CobdenCobden
10.0 out of 10, Exceptional, (1 review)
The price is ¥29,463
¥35,287 total
includes taxes & fees
Nov 16 - Nov 17
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Cape Girardeau
Explore the mighty Mississippi from the riverfront park where historic murals tell stories of river life. Climb to the top of Academic Hall at Southeast Missouri State or hunt for antiques along downtown's brick-paved streets.

Top reviews in Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau

























































































































