Photo by Skyy

Search Vacation Homes in Cape Girardeau

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Compare 41 Vacation Homes in Cape Girardeau with updated reviews, rates, and availability.

Beautiful location in the secluded woods
10.0 out of 10, Exceptional, (12)
"All I have to say is this was an amazing experience we have had as a family. Not only the host had EVERYTHING perfect and was absolutely a huge help with suggestions and ideas for the area but this was a perfect place to stay and not only enjoyed having time with one another but the huge lot gave us time to explore, play baseball and even our dog absolutely loved running wild! There is winery and brewery around the corner. There is enough places to hike and explorer. The home is in a perfect...
The price is ¥13,766
¥23,910 total
includes taxes & fees
Sep 29 - Sep 30
Beautiful location in the secluded woods
Notting Hill Cottage
9.6 out of 10, Exceptional, (289)
"This property was so cute and perfect for our anniversary. It's quiet and private, but not too far from the highway and attractions such as the wine trail and hiking. The owners responded quickly when I had questions. We will definitely consider coming back here and maybe even bringing our children, as their is enough space for all of us. "
Notting Hill Cottage
* On the Wine Trail * Hot Tub * Wi-Fi *
9.8 out of 10, Exceptional, (205)
"We love checking out the wine trail and the many great hiking trails in the area. This property is perfectly located for such."
* On the Wine Trail * Hot Tub * Wi-Fi *
Spacious 3 bedroom, 2 full baths, hot tub, fireplace, full kitchen, outside deck
9.6 out of 10, Exceptional, (9)
"We spent our annual girls trip at this property and it did not disappoint! The host responds very quickly. The property was clean, beautiful and cozy. We were very happy with it and would definitely stay again!"
Spacious 3 bedroom, 2 full baths, hot tub, fireplace, full kitchen, outside deck
Wine Trail, Cozy Cabin plus hot tub
10.0 out of 10, Exceptional, (77)
"quiet peaceful relaxing getting away hot tub was great"
Wine Trail, Cozy Cabin plus hot tub
Spacious 2 BR, 1 1/2 baths, hot tub, pool table, outside room, full kitchen
9.8 out of 10, Exceptional, (134)
"Stayed two nights... The location was great and exceeded my expectations. We had a lovely time and would happily consider coming back someday."
Spacious 2 BR, 1 1/2 baths, hot tub, pool table, outside room, full kitchen
Little Blue Cottage on Spanish
8.8 out of 10, Excellent, (35)
"We stay here every time we come to the area from Tennessee, it's small and cozy, perfect for you and your significant other, host is very nice and communicative. It's located within walking distance of downtown Cape shops, highly recommend this home"
The price is ¥13,019
¥15,912 total
includes taxes & fees
Oct 2 - Oct 3
Little Blue Cottage on Spanish
Conveniently Located Modern Home -- Downtown-River-Casino-SEMO-Hospital
10.0 out of 10, Exceptional, (2)
"It was a family, working, long weekend but we enjoyed the time we spent in the rental."
Conveniently Located Modern Home -- Downtown-River-Casino-SEMO-Hospital
Serenity South -- Gardens, River-Views, and Refreshing Space
10.0 out of 10, Exceptional, (120)
"Nice property, real close to downtown and the river. Very relaxing "
The price is ¥21,699
¥35,290 total
includes taxes & fees
Oct 2 - Oct 3
Serenity South -- Gardens, River-Views, and Refreshing Space
* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *
10.0 out of 10, Exceptional, (84)
"So many good things about this house- great location, so cute, stocked with snacks. My two complaints are 1) the furniture. The couch and chairs are flaking leather, and it’s all over the floors. You can’t lay on the couch, the flakes get everywhere then. I found them in the bed, in my hair… I think that needs to be taken care of. 2) we found a dead mouse in a trap under the couch. Really wish that would have been checked and dealt with before we got there. All in all, I do recommend this house...
* Best Location on the Wine Trail! * Hiking Trail 1 min away * Wi-Fi *
Victorian home brought back to life on the Shawnee Hills wine trail.
10.0 out of 10, Exceptional, (11)
"Absolutely perfect house, had a wonderful time going to the wineries and then relaxing in the evening in the hot tub and by the fire."
Victorian home brought back to life on the Shawnee Hills wine trail.
On the Wine Trail - Minutes to Giant City, Shawnee Forest, SIU - Amazing Shower
10.0 out of 10, Exceptional, (163)
"Nice place, easy check in and good communication. Could use a new sofa. The outdoor area needs landscaping, privacy, and new chair cushions. A bit pricey."
On the Wine Trail - Minutes to Giant City, Shawnee Forest, SIU - Amazing Shower
Minutes from WineTrail, Giant City, Shawnee Forest - Daily Deer Viewing - Rural
10.0 out of 10, Exceptional, (108)
"If you are looking for peace and quiet in wine country this is definitely the place. We stayed for almost a month and explored the area pretty thoroughly. There is a lot within an hours drive to do in Missouri, Kentucky, and Illinois of course. The host is incredible!!!!"
Minutes from WineTrail, Giant City, Shawnee Forest - Daily Deer Viewing - Rural
Charming 2-Story- C.1847 - River Views - Fast Wifi
9.6 out of 10, Exceptional, (13)
"We had a nice stay. The house was clean and served our purpose. The only negative was the downstairs bathroom, we only used the shower once due to water going all over the floor. It isn’t a shower stall but a drain in the floor with an inadequate lip to keep the water contained "
Charming 2-Story- C.1847 - River Views - Fast Wifi
Betty's Vineyard House - On the Shawnee Wine Trail - Walk to/from the Winery!
10.0 out of 10, Exceptional, (67)
"What am awesome place to stay, with even better owners. Wow! How could you not love being able to WALK to Alto Vineyards AND be centrally located to all the fun things. Thank you, Beth. You're truly one of the best, and we've been renting vacation properties for 25 years!"
Betty's Vineyard House - On the Shawnee Wine Trail - Walk to/from the Winery!
Winery on Property and located directly on the wine trail
9.8 out of 10, Exceptional, (28)
"Very good communication with host before and during stay. House was super clean and very cute. There were a lot of kitchen appliances, dishes, cooking pots and pans. Quiet and peaceful, even with Meadery on the property. Our only “complaint” is that the furniture in both upstairs and downstairs living areas was not super comfortable for long term sitting. Otherwise, highly recommended 💕"
Winery on Property and located directly on the wine trail
Cozy Anna Home Near Southern Illinois Attractions!
10.0 out of 10, Exceptional, (1)
"We definitely enjoyed our stay. The house is so clean and has everything!! We hope to come back."
Cozy Anna Home Near Southern Illinois Attractions!
Charming 3-bedroom house near downtown
2.0 star property
10.0 out of 10, Exceptional, (1)
"My husband and I along with one other couple stayed here while in Cape for a wedding. The location was nice and was a short distance for driving or Ubering around town. The price was great!! Highly recommend."
Charming 3-bedroom house near downtown
Serene Private Retreat Close to Shawnee National Forest
The price is ¥22,422
¥58,920 total
includes taxes & fees
Oct 8 - Oct 9
Serene Private Retreat Close to Shawnee National Forest
Beautiful Cabin Retreat
8.2 out of 10, Very Good, (39)
"Host had the cabin very clean. New leather couch & recliner. Mattress was extremely comfortable. Washer & Dryer were excellent. Another Rental house near, long-term renters were very quiet. Internet not very good in the Illinois woods. Closed cabin has a musty smell from humidity in the woods. Host had an automatic air freshener going to help with air quality."
The price is ¥17,359
¥27,919 total
includes taxes & fees
Oct 3 - Oct 4
Beautiful Cabin Retreat
Don't see what you're looking for?
See all available properties in Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Other property types in Cape Girardeau

Little Blue Cottage on Spanish
8.8 out of 10, Excellent, (35)
"We stay here every time we come to the area from Tennessee, it's small and cozy, perfect for you and your significant other, host is very nice and communicative. It's located within walking distance of downtown Cape shops, highly recommend this home"
The price is ¥13,019
¥15,912 total
includes taxes & fees
Oct 2 - Oct 3
Little Blue Cottage on Spanish
Loft Apartment Across From Semo University Houch Field House. Walk To Events
10.0 out of 10, Exceptional, (76)
"Super fun place to stay if you are visiting for a home SEMO game! We will be back! "
The price is ¥21,737
¥26,519 total
includes taxes & fees
Oct 17 - Oct 18
Loft Apartment Across From Semo University Houch Field House. Walk To Events
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
9.8 out of 10, Exceptional, (26)
"It was wonderful."
The price is ¥13,164
¥21,404 total
includes taxes & fees
Oct 2 - Oct 3
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.