Cape Girardeau Vacation Rentals

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Our top choices for Cape Girardeau vacation rentals

Charming Secluded Getaway Cabin within minutes of amenities

Charming Secluded Getaway Cabin within minutes of amenities
Cape girardeau
10.0 out of 10, Exceptional, (18 reviews)
"We had a great time at Blair and her family's property. The cabin was very comfortable and as advertised. I would be happy to recommend it to others "
United States
Tammy M.
The price is ¥24,577
¥48,615 total
includes taxes & fees
Apr 10 - Apr 11
Charming Secluded Getaway Cabin within minutes of amenities

Gorgeous 1856 Log Cabin, Completely Renovated

Gorgeous 1856 Log Cabin, Completely Renovated
Jackson
10.0 out of 10, Exceptional, (3 reviews)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
United States
Chandler G.
The price is ¥31,712
¥49,154 total
includes taxes & fees
Apr 12 - Apr 13
Gorgeous 1856 Log Cabin, Completely Renovated

The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse
Cape Girardeau
10.0 out of 10, Exceptional, (33 reviews)
"Amazing stay, loved the bed and hot tub. Close to town but also away. "
United States
Maria B.
The price is ¥32,679
¥47,530 total
includes taxes & fees
Apr 22 - Apr 23
The Twisted Sassafras Treehouse

Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space
Cape Girardeau
10.0 out of 10, Exceptional, (152 reviews)
"Wonderful location! WonderfulStay"
United States
Alison C.
The price is ¥23,784
¥39,263 total
includes taxes & fees
Apr 14 - Apr 15
Serenity South -- Gardens, River-Views, and Refreshing Space

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (39 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is ¥21,406
¥34,503 total
includes taxes & fees
Apr 15 - Apr 16
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.6 out of 10, Exceptional, (9 reviews)
"Nice place, great times"
United States
Jace W.
The price is ¥42,668
¥69,327 total
includes taxes & fees
Apr 15 - Apr 16
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.2 out of 10, Very Good, (54 reviews)
"Cozy and perfect for a couple. Great communication with the host"
United States
Beth G.
The price is ¥12,843
¥17,146 total
includes taxes & fees
Apr 10 - Apr 11
Little Blue Cottage on Spanish

The Cottage, Rusted Route Farms

The Cottage, Rusted Route Farms
Jackson
10.0 out of 10, Exceptional, (2 reviews)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
The price is ¥19,820
¥31,553 total
includes taxes & fees
May 10 - May 11
The Cottage, Rusted Route Farms

Modern 2BR Apt w Electric Fireplace By KeenStays

Modern 2BR Apt w Electric Fireplace By KeenStays
Cape Girardeau
The price is ¥15,892
¥32,574 total
includes taxes & fees
Apr 13 - Apr 14
Modern 2BR Apt w Electric Fireplace By KeenStays

Fresh & Cozy Retreat w/ King Bed · By KeenStays

Fresh & Cozy Retreat w/ King Bed · By KeenStays
Cape Girardeau
The price is ¥12,685
¥26,508 total
includes taxes & fees
May 10 - May 11
Fresh & Cozy Retreat w/ King Bed · By KeenStays

Luxe 2KBR Apt w/ Electric Fireplace · By KeenStays

Luxe 2KBR Apt w/ Electric Fireplace · By KeenStays
Cape Girardeau
The price is ¥15,892
¥32,892 total
includes taxes & fees
Apr 13 - Apr 14
Luxe 2KBR Apt w/ Electric Fireplace · By KeenStays

Luxury 4BR Log Cabin Near SIU & Wine Trail

Luxury 4BR Log Cabin Near SIU & Wine Trail
Makanda
10.0 out of 10, Exceptional, (48 reviews)
"Had a great time at this property "
United States
Shaquana G.
The price is ¥68,775
¥85,503 total
includes taxes & fees
Apr 12 - Apr 13
Luxury 4BR Log Cabin Near SIU & Wine Trail

Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre
Dongola
10.0 out of 10, Exceptional, (102 reviews)
"Enjoyed our stay great hospitality, everything we needed was addressed. We would highly recommend staying there. Great location "
United States
carlton h.
The price is ¥21,406
¥45,035 total
includes taxes & fees
Apr 11 - Apr 12
Charming cottage overlooking Lake Acre

Contemporary Glamping with Native American Appeal

Contemporary Glamping with Native American Appeal
Anna
9.8 out of 10, Exceptional, (158 reviews)
"They hosts are very welcoming and attentive. The home was clean and prepped for our visit. "
United States
Lynette G.
The price is ¥26,752
¥50,915 total
includes taxes & fees
Apr 14 - Apr 15
Contemporary Glamping with Native American Appeal

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Anna
10.0 out of 10, Exceptional, (407 reviews)
"Great location. Cozy cabin. Would stay there again. "
United States
jeffrey s
The price is ¥18,552
¥31,762 total
includes taxes & fees
Apr 16 - Apr 17
Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Relax in the country at Countryside Villas! - Villa A

Relax in the country at Countryside Villas! - Villa A
Jackson
10.0 out of 10, Exceptional, (33 reviews)
"Great place to stay, felt like home away from home. "
United States
Brittany
The price is ¥23,784
¥28,476 total
includes taxes & fees
Apr 10 - Apr 11
Relax in the country at Countryside Villas! - Villa A

Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake
Miller City
9.8 out of 10, Exceptional, (24 reviews)
"The cabin is perfect for a quiet getaway. Location is great close to Dollar General, gas station and restaurants"
United States
Marsha G.
The price is ¥15,697
¥26,719 total
includes taxes & fees
Apr 10 - Apr 11
Peaceful secluded cabin located near Horseshoe Lake

Magical Victorian near hiking / wine trail

Magical Victorian near hiking / wine trail
Anna
10.0 out of 10, Exceptional, (7 reviews)
"The house was beautiful! We were in awe of the decor and layout. This is a must-stay if you are in southern Illinois!"
United States
Lori C.
The price is ¥37,293
¥67,061 total
includes taxes & fees
Apr 12 - Apr 13
Magical Victorian near hiking / wine trail

Villa B offers peace and quiet with beautiful views of the countryside.

Villa B offers peace and quiet with beautiful views of the countryside.
Jackson
10.0 out of 10, Exceptional, (11 reviews)
"It was great. "
United States
Benjamin Q.
The price is ¥23,784
¥28,476 total
includes taxes & fees
May 10 - May 11
Villa B offers peace and quiet with beautiful views of the countryside.

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Makanda
9.8 out of 10, Exceptional, (63 reviews)
"Stephen very friendly and accomadations excellent!"
United States
Walter H.
The price is ¥14,905
¥28,701 total
includes taxes & fees
May 4 - May 5
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau Hotel Reviews

Find out more about Cape Girardeau

Search for holiday rentals in Cape Girardeau on Expedia! You can easily find your home rentals, villas, holiday apartments in Cape Girardeau using one of the methods below:

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Frequently asked questions

Can I find vacation rentals in Cape Girardeau?

Yes, we offer vacation rentals in Cape Girardeau near Cape Splash Family Aquatic Center, or you can select a more remote option if you're looking for extra privacy while you relax. Visitors like the top-notch restaurants and shops in Cape Girardeau. Make sure you allow time to enjoy the riverfront during your vacation.

What are some of the best vacation home rentals in Cape Girardeau?

“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau: This Cape Girardeau vacation home rental is located on a river and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. Some other homes for rent in Cape Girardeau include Little Blue Cottage on Spanish and 3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau.

How many vacation rentals will I find in Cape Girardeau?

Choose from 21 Expedia vacation rentals in Cape Girardeau for a memorable vacation.

What can I see and do in Cape Girardeau?

Family-friendly attractions include Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center, whereas Shawnee National Forest and Mississippi River are a couple of great spots to enjoy the outdoors. While here, Century Casino & Hotel Cape Girardeau and Show Me Center are other places worth a visit.

What are vacation rentals like in Cape Girardeau?

Vacation rentals are private properties you can book for a couple days or more in Cape Girardeau. Vacation rentals offer amenities such as hot tubs, fire pits, and patios so your stay will be comfortable. If you're concerned about cleanliness, vacation rentals can offer a sense of privacy away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for a small group gathering.