Cape Girardeau Vacation Rentals

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Our top choices for Cape Girardeau vacation rentals

Charming Secluded Getaway Cabin within minutes of amenities

Charming Secluded Getaway Cabin within minutes of amenities
Cape girardeau
10.0 out of 10, Exceptional, (18 reviews)
"We had a great time at Blair and her family's property. The cabin was very comfortable and as advertised. I would be happy to recommend it to others "
United States
Tammy M.
The price is ¥24,033
¥45,275 total
includes taxes & fees
Feb 23 - Feb 24
Charming Secluded Getaway Cabin within minutes of amenities

Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very Good, (50 reviews)
"Cozy and perfect for a couple. Great communication with the host"
United States
Beth G.
The price is ¥12,559
¥15,660 total
includes taxes & fees
Feb 23 - Feb 24
Little Blue Cottage on Spanish

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (39 reviews)
"Very nice house. The pool and hot tub were perfect for a short getaway. Tons of activities and games to keep the fanily entertained. Will definitely come back! "
United States
Emily D.
The price is ¥20,932
¥33,144 total
includes taxes & fees
Feb 23 - Feb 24
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

Gorgeous 1856 Log Cabin, Completely Renovated

Gorgeous 1856 Log Cabin, Completely Renovated
Jackson
10.0 out of 10, Exceptional, (3 reviews)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
United States
Chandler G.
The price is ¥31,010
¥46,825 total
includes taxes & fees
Mar 15 - Mar 16
Gorgeous 1856 Log Cabin, Completely Renovated

Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space
Cape Girardeau
10.0 out of 10, Exceptional, (151 reviews)
"Such a great place and location"
United States
Tracy H.
The price is ¥23,258
¥38,394 total
includes taxes & fees
Feb 23 - Feb 24
Serenity South -- Gardens, River-Views, and Refreshing Space

The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse
Cape Girardeau
10.0 out of 10, Exceptional, (30 reviews)
"This is the perfect private romantic getaway! We had such a blast here. Definitely recommend!"
United States
Eric S.
The price is ¥37,057
¥53,235 total
includes taxes & fees
Mar 9 - Mar 10
The Twisted Sassafras Treehouse

The Cottage, Rusted Route Farms

The Cottage, Rusted Route Farms
Jackson
10.0 out of 10, Exceptional, (2 reviews)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
The price is ¥19,381
¥30,235 total
includes taxes & fees
Feb 23 - Feb 24
The Cottage, Rusted Route Farms

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.6 out of 10, Exceptional, (8 reviews)
"Nice place, great times"
United States
Jace W.
The price is ¥41,724
¥66,915 total
includes taxes & fees
Feb 23 - Feb 24
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Makanda
9.8 out of 10, Exceptional, (61 reviews)
"Stephen very friendly and accomadations excellent!"
United States
Walter H.
The price is ¥14,575
¥28,066 total
includes taxes & fees
Feb 24 - Feb 25
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Anna
10.0 out of 10, Exceptional, (405 reviews)
"Nice cabin and beautiful scenery! We enjoyed our stay."
United States
Hannah G.
The price is ¥18,141
¥31,058 total
includes taxes & fees
Feb 24 - Feb 25
Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Makanda
9.6 out of 10, Exceptional, (43 reviews)
"Everything was very nice. We enjoyed our stay! The cabin had everything we needed."
United States
Cheri U.
The price is ¥16,900
¥32,696 total
includes taxes & fees
Feb 23 - Feb 24
Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre
Dongola
10.0 out of 10, Exceptional, (102 reviews)
"Great place so peaceful and relaxing "
United States
Paul D.
The price is ¥20,932
¥43,544 total
includes taxes & fees
Feb 24 - Feb 25
Charming cottage overlooking Lake Acre

Contemporary Glamping with Native American Appeal

Contemporary Glamping with Native American Appeal
Anna
9.8 out of 10, Exceptional, (158 reviews)
"Every Th I was perfect close to the shopping we wanted to and such quiet area "
United States
Christina S.
The price is ¥27,785
¥50,920 total
includes taxes & fees
Feb 23 - Feb 24
Contemporary Glamping with Native American Appeal

Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake
Miller City
10.0 out of 10, Exceptional, (21 reviews)
"The cabin is perfect for a quiet getaway. Location is great close to Dollar General, gas station and restaurants"
United States
Marsha G.
The price is ¥17,443
¥28,346 total
includes taxes & fees
Feb 23 - Feb 24
Peaceful secluded cabin located near Horseshoe Lake

Fantastic 1-bedroom Cabin in peaceful Makanda, Pet-Friendly!

Fantastic 1-bedroom Cabin in peaceful Makanda, Pet-Friendly!
Makanda
10.0 out of 10, Exceptional, (2 reviews)
"Great host, amenities, and location!"
United States
Kevin W.
The price is ¥11,660
¥15,645 total
includes taxes & fees
Feb 23 - Feb 24
Fantastic 1-bedroom Cabin in peaceful Makanda, Pet-Friendly!

Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
9.8 out of 10, Exceptional, (35 reviews)
"Beautiful place, host was kind and and quick to respond to messages "
United States
Melissa W.
The price is ¥17,443
¥21,774 total
includes taxes & fees
Feb 23 - Feb 24
Cozy cabins on beautiful Horseshoe Lake

Beautiful location in the secluded woods

Beautiful location in the secluded woods
Pomona
10.0 out of 10, Exceptional, (64 reviews)
"It was very nice and clean. We really enjoyed staying there. We would love to rent this place again. "
United States
susan B.
The price is ¥13,706
¥26,029 total
includes taxes & fees
Feb 24 - Feb 25
Beautiful location in the secluded woods

Cozy and Updated Farmhouse with King Suite

Cozy and Updated Farmhouse with King Suite
Anna
10.0 out of 10, Exceptional, (3 reviews)
"Kayla was quick to answer any questions. Her description of the place is very accurate. Beautifully remodeled. Spacious. Comfortable beds. We rented because it's the perfect location if you want to explore Giant City and Ferne Clyffe. We didn't have time this time but there are numerous parks and biking trails nearby. I highly recommend it."
United States
Ronda H.
The price is ¥12,280
¥22,875 total
includes taxes & fees
Mar 1 - Mar 2
Cozy and Updated Farmhouse with King Suite

Charming 2-bedroom apartment in fabulous Marble Hill with AC

Charming 2-bedroom apartment in fabulous Marble Hill with AC
Marble Hill
7.6 out of 10, Good, (5 reviews)
"Host was not properly notified of the booking, but made the accommodations made several trips to make sure we were checked in and comfortable. Also gave very good advice for local points of interest."
United States
Chrystine H.
The price is ¥11,861
¥20,663 total
includes taxes & fees
Feb 23 - Feb 24
Charming 2-bedroom apartment in fabulous Marble Hill with AC

Contemporary Glamping with Native American Appeal!

Contemporary Glamping with Native American Appeal!
Anna
10.0 out of 10, Exceptional, (102 reviews)
"Would love to rent it again, was cozy clean private and perfect Thanks Mary for taking the extra mile and helping with turning of heat"
United States
Ravi Sankar Reddy K.
The price is ¥27,289
¥52,607 total
includes taxes & fees
Feb 23 - Feb 24
Contemporary Glamping with Native American Appeal!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau Hotel Reviews

Find out more about Cape Girardeau

Search for holiday rentals in Cape Girardeau on Expedia! You can easily find your home rentals, villas, holiday apartments in Cape Girardeau using one of the methods below:

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Frequently asked questions

Can I find vacation rentals in Cape Girardeau?

Yes, we offer vacation rentals in Cape Girardeau near Cape Splash Family Aquatic Center, or you can select a more remote option if you're looking for extra privacy while you relax. Visitors like the top-notch restaurants and shops in Cape Girardeau. Make sure you allow time to enjoy the riverfront during your vacation.

What are some of the best vacation home rentals in Cape Girardeau?

“Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau: This Cape Girardeau vacation home rental is located on a river and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. Some other homes for rent in Cape Girardeau include Little Blue Cottage on Spanish and 3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau.

How many vacation rentals will I find in Cape Girardeau?

Choose from 20 Expedia vacation rentals in Cape Girardeau for a memorable vacation.

What can I see and do in Cape Girardeau?

Family-friendly attractions include Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center, whereas Shawnee National Forest and Mississippi River are a couple of great spots to enjoy the outdoors. While here, Isle Casino Cape Girardeau and Show Me Center are other places worth a visit.

What are vacation rentals like in Cape Girardeau?

Vacation rentals are private properties you can book for a couple days or more in Cape Girardeau. Vacation rentals offer amenities such as hot tubs, fire pits, and patios so your stay will be comfortable. If you're concerned about cleanliness, vacation rentals can offer a sense of privacy away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for a small group gathering.