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Cape Girardeau Vacation Rentals

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Check prices for these dates

Tonight
Jul 25 - Jul 26
Tomorrow
Jul 26 - Jul 27
This weekend
Jul 25 - Jul 27
Next weekend
Aug 1 - Aug 3

Vacation Rentals in Cape Girardeau

Serenity South -- Gardens, River-Views, and Refreshing Space
Enjoy cooking in this well-equipped kitchen with a refrigerator, microwave, and coffee maker.

Serenity South -- Gardens, River-Views, and Refreshing Space

10.0 out of 10, Exceptional, (136)
"The property was exactly as listed with so many little touches that made it special. Communication was great and we were close to downtown shops and the casino. We will definitely stay again when we are in the area."
The price is ￥22,061
￥36,025 total
includes taxes & fees
Jul 26 - Jul 27
Serenity South -- Gardens, River-Views, and Refreshing Space
Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.
Stately brick building with a central entrance and steps.

Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.

8.6 out of 10, Excellent, (16)
"Very clean and spacious. Great location with River Walk and several good restaurants within walking distance. Check in was smooth and host was very responsive. "
Downtown 4BR with 2 King Beds! Walking distance to SEMO and the River Front.
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Efficient kitchen space with central island, microwave, and sink.

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

9.8 out of 10, Exceptional, (35)
"Nice place to stay! Clean, able to walk to everything!"
The price is ￥12,045
￥20,346 total
includes taxes & fees
Jul 27 - Jul 28
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Special Offer for Weekly & Monthly Stays in August & September at "Brickyard"
Enjoy cooking in this well-equipped kitchen with a central island, stove, and stainless steel refrigerator.

Special Offer for Weekly & Monthly Stays in August & September at "Brickyard"

10.0 out of 10, Exceptional, (20)
"Chip was an excellent host, always available to provide tips about restaurants and answer any questions about the property. Property was in great condition and would not hesitate to recommend."
Special Offer for Weekly & Monthly Stays in August & September at "Brickyard"
Loft Apartment Across From Semo University Houch Field House. Walk To Events
Compact kitchen with modern design, stainless steel appliances, and a dining area.

Loft Apartment Across From Semo University Houch Field House. Walk To Events

10.0 out of 10, Exceptional, (88)
"Very nice place! I needed a place to stay for the month for clinical rotations for school, and the property owner worked with me with pricing. The loft is in the middle of everything in Cape! Highly recommend."
The price is ￥21,968
￥26,654 total
includes taxes & fees
Aug 7 - Aug 8
Loft Apartment Across From Semo University Houch Field House. Walk To Events
Little Blue Cottage on Spanish
Kitchen area with sink, cabinets, and countertop.

Little Blue Cottage on Spanish

8.6 out of 10, Excellent, (42)
"Has everything you need. Comfy and in a great location. "
The price is ￥11,913
￥14,854 total
includes taxes & fees
Jul 27 - Jul 28
Little Blue Cottage on Spanish
The Twisted Sassafras Treehouse
Relax on the deck with a cushioned chair and small table, surrounded by lush greenery.

The Twisted Sassafras Treehouse

10.0 out of 10, Exceptional, (16)
"My wife and I thoroughly enjoyed our stay here! A beautiful place built on a beautiful property; we enjoyed the hot tub under the stars and the morning coffee on the porch (and another hot tub ). Great place for some R&R, and excellent communication with the owner in advance. Wouldn’t hesitate to book again."
The price is ￥30,311
￥44,337 total
includes taxes & fees
Aug 4 - Aug 5
The Twisted Sassafras Treehouse
Quaint, Beautiful Home next to SEMO and Hospital
Situated in a suburban neighborhood, this two-story house features a gabled roof and a front entrance.

Quaint, Beautiful Home next to SEMO and Hospital

9.8 out of 10, Exceptional, (36)
"Great stay, great location! "
Quaint, Beautiful Home next to SEMO and Hospital
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Enjoy a serene river view from this balcony, featuring a table and chairs, and a shaded seating area.

Historical 'Kage House' Short Term Rental located in "Old Town Cape"

10.0 out of 10, Exceptional, (217)
"This is our second time staying at the Kage House. Didnt disappoint at all. Great location! "
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Enjoy a tranquil retreat with a pool and lush surroundings.

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

8.8 out of 10, Excellent, (32)
"all was so nice and we enjoyed our stay. grandkids and us loved having pool table and card games and all the peace and quiet there. thank u again for contacting me and giving us address. we appreciated that very much. "
The price is ￥26,340
￥39,767 total
includes taxes & fees
Jul 27 - Jul 28
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Charming Secluded Getaway Cabin within minutes of amenities
Cozy cabin-style retreat with a front porch and lush surroundings.

Charming Secluded Getaway Cabin within minutes of amenities

10.0 out of 10, Exceptional, (14)
"Nice little Cabin in a beautiful area. Blair and her family were wonderful!"
Charming Secluded Getaway Cabin within minutes of amenities
Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi
Enjoy cooking in this well-equipped kitchen with a stainless steel range hood, oven, and double sink.

Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi

10.0 out of 10, Exceptional, (7)
"Lovely home with historic architectural features in tact. Fully stocked, great location, quite neighborhood. We thoroughly enjoyed our stay."
Historic Victorian - Walkable to Downtown Cape Girardeau - King Bed - Fast Wifi
Gorgeous 1856 Log Cabin, Completely Renovated
Stately entrance with a black door, flanked by urns, and a wooden porch supported by columns.

Gorgeous 1856 Log Cabin, Completely Renovated

10.0 out of 10, Exceptional, (3)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
The price is ￥29,414
￥45,886 total
includes taxes & fees
Jul 27 - Jul 28
Gorgeous 1856 Log Cabin, Completely Renovated
Downtown Cape 2 Bdrm/2 Bath Apt, Cozy & Walkable
Enjoy cooking in this well-equipped kitchen with a refrigerator, oven, and dishwasher.

Downtown Cape 2 Bdrm/2 Bath Apt, Cozy & Walkable

10.0 out of 10, Exceptional, (1)
"Great location and the one issue was resolved quickly and no fault of the property owner. "
Downtown Cape 2 Bdrm/2 Bath Apt, Cozy & Walkable
Next Door to Mercy Hospital - Pet Friendly - Fast Wifi
Enjoy cooking in this well-equipped kitchen with a central island, dining table, and sink.

Next Door to Mercy Hospital - Pet Friendly - Fast Wifi

8.0 out of 10, Very Good, (5)
"This is the first year we’ve stayed at anyplace other than a hotel for homecoming weekend. This place was terrific. Cute and clean with everything you need - even a box fan for my husband who travels with ours so he can sleep! The location is very convenient. We will absolutely stay here again! "
Next Door to Mercy Hospital - Pet Friendly - Fast Wifi
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Enjoy an outdoor space with a well-maintained lawn and a circular swimming pool.

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

9.2 out of 10, Wonderful, (5)
"Great property would recommend 100%. We did not have to leave the house it had everything we needed for nine adult women to have a great streetlight"
The price is ￥46,132
￥72,070 total
includes taxes & fees
Jul 27 - Jul 28
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
River's Dusk - Modernized Historic Home - River Views - King Bed - Fast Wifi
Enjoy cooking in this well-equipped kitchen with a brick accent wall, modern appliances, and ample natural light.

River's Dusk - Modernized Historic Home - River Views - King Bed - Fast Wifi

10.0 out of 10, Exceptional, (1)
"This was a cute place."
River's Dusk - Modernized Historic Home - River Views - King Bed - Fast Wifi
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Enjoy a peaceful retreat in this charming cabin, surrounded by trees and a grassy area, with a front porch featuring two rocking chairs.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

10.0 out of 10, Exceptional, (389)
"Gorgeous and comfortable property with front porch and back deck. "
The price is ￥17,135
￥30,223 total
includes taxes & fees
Jul 31 - Aug 1
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Beautiful location in the secluded woods
Relax on the covered porch with a table and four chairs, surrounded by lush greenery.

Beautiful location in the secluded woods

10.0 out of 10, Exceptional, (39)
"If you're looking to visit Holy Boulders, this spot gets you within 5-10 minutes of either trailhead. It was clean, roomy, and has everything you need when you're not at the crag."
The price is ￥14,499
￥24,751 total
includes taxes & fees
Aug 4 - Aug 5
Beautiful location in the secluded woods
Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery
Escape to a cozy cabin nestled in a serene forest setting, offering a welcoming entrance and outdoor seating area.

Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery

10.0 out of 10, Exceptional, (137)
"This cabin was so nice and clean. The beds were very comfortable and this was the perfect location!"
Brand new cabin in the woods with hot tub 1/2 mile from Starview Winery
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau Hotel Reviews

The Riverview

The Riverview

10/10 Excellent
"The beds were amazing! The room was big and everything was in perfect condition. Will def recommend to other and will be back myself. "
Casey 1-night trip
Posted 2 days ago
The Riverview

Frequently asked questions

Can I find vacation rentals in Cape Girardeau?

Yes, we offer vacation rentals in Cape Girardeau near Cape Splash Family Aquatic Center, or you can select a more remote option if you're looking for extra privacy while you relax. Visitors like the top-notch restaurants and shops in Cape Girardeau. Make sure you allow time to enjoy the riverfront during your vacation.

What are some of the best vacation home rentals in Cape Girardeau?

Serenity South -- Gardens, River-Views, and Refreshing Space: This Cape Girardeau vacation home rental is located on a river and has a fireplace, a balcony, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. Some other homes for rent in Cape Girardeau include "Brickyard" Remodeled 1920's Dutch Colonial Revival in Downtown Cape Girardeau and Little Blue Cottage on Spanish.

How many vacation rentals will I find in Cape Girardeau?

Choose from 23 Expedia vacation rentals in Cape Girardeau for a memorable vacation.

What can I see and do in Cape Girardeau?

Family-friendly attractions include Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center, whereas Shawnee National Forest and Mississippi River are a couple of great spots to enjoy the outdoors. While here, Isle Casino Cape Girardeau and Show Me Center are other places worth a visit.

What are vacation rentals like in Cape Girardeau?

Vacation rentals are private properties you can book for a couple days or more in Cape Girardeau. Vacation rentals offer amenities such as hot tubs, fire pits, and patios so your stay will be comfortable. If you're concerned about cleanliness, vacation rentals can offer a sense of privacy away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for a small group gathering.