Cairo Ohio River Bridge traversing over the Ohio River at sunset

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Check availability on Cairo Resorts & Hotels with Spas

Next weekend
Jun 26 - Jun 28
In two weeks
Jul 3 - Jul 5
No exact matches found, but these alternatives could be just right

Recommended hotels in Cairo

Lobby

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (288 reviews)
The price is ￥11,024
￥12,235 total
includes taxes & fees
Jul 10 - Jul 11
Quality Inn Cairo I-57
Exterior

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (416 reviews)
The price is ￥12,095
￥13,423 total
includes taxes & fees
Jun 21 - Jun 22
The Riverstone Hotel Charleston-Sikeston
Basic Double Room | Living area

La Center Motel

La Center Motel
2.0 star property
La Center
7.4 out of 10, Good, (20 reviews)
The price is ￥8,708
￥10,187 total
includes taxes & fees
Jun 21 - Jun 22
La Center Motel
Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (641 reviews)
The price is ￥9,597
￥10,650 total
includes taxes & fees
Jul 12 - Jul 13
Super 8 by Wyndham Charleston/Sikeston East MO
House (2 Bedrooms) | Interior

Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
The price is ￥19,512
￥46,760 total
includes taxes & fees
Jul 8 - Jul 9
Quiet Country Stay: Modern Home Near Paducah
Shower, towels, soap, shampoo

The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.4 out of 10, Exceptional, (31 reviews)
The price is ￥18,146
￥22,651 total
includes taxes & fees
Jun 21 - Jun 22
The Rested Duck Mallard Room
Dining

Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
10.0 out of 10, Exceptional, (41 reviews)
The price is ￥18,142
￥22,646 total
includes taxes & fees
Jun 22 - Jun 23
Cozy cabins on beautiful Horseshoe Lake
Property grounds

Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre
Dongola
10.0 out of 10, Exceptional, (104 reviews)
The price is ￥21,770
￥45,288 total
includes taxes & fees
Jun 21 - Jun 22
Charming cottage overlooking Lake Acre
Room, 1 King Bed, Non Smoking | View from room

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (106 reviews)
The price is ￥11,530
￥12,796 total
includes taxes & fees
Jun 22 - Jun 23
Eagle Inn Charleston
Smart TV

Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake
Miller City
9.8 out of 10, Exceptional, (28 reviews)
The price is ￥18,146
￥29,660 total
includes taxes & fees
Jun 21 - Jun 22
Peaceful secluded cabin located near Horseshoe Lake
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Cairo

Pool
Breakfast included

Top Cairo Hotel Reviews

Eagle Inn Charleston

Eagle Inn Charleston

10/10 Excellent
"Great"
Jackson 1-night trip
Posted 3 months ago
Eagle Inn Charleston

Frequently asked questions

Looking for a spa hotel in Cairo?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Check out the historical sites and restaurants in Cairo—your day trip starts here. Enjoy the opera and riverfront during your vacation. Hotels with spas are the perfect way to break out of your routine and add a layer of luxury to your vacation.
What's there to see and do in Cairo?
When you're in Cairo, enjoy exploring the sights and attractions here including Mississippi River, Ohio River Valley, and Fort Defiance State Park. If you have a little extra time during your trip, you might want to check out Ballard Wildlife Management Area and Columbus-Belmont State Park.
What is a Cairo spa hotel?
Spa hotels in Cairo provide lodging and have an on-site spa offering services including couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.