Find Luxury Hotels in Cairo, IL

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Cairo Luxury Hotels

No exact matches found, but these alternatives could be just right

Recommended hotels in Cairo

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (278 reviews)
"The quality was not what I expected for a "Quality Inn". It felt more light a Motel 6. I was not satisfied at all."
United States
ReShena
The price is ¥10,329
¥11,463 total
includes taxes & fees
Mar 6 - Mar 7
Quality Inn Cairo I-57

La Center Motel

La Center Motel
2.0 star property
La Center
7.8 out of 10, Good, (17 reviews)
"Quiet and convenient."
United States
Alma
La Center Motel

Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre
Dongola
10.0 out of 10, Exceptional, (102 reviews)
"Great place so peaceful and relaxing "
United States
Paul D.
The price is ¥20,615
¥42,885 total
includes taxes & fees
Feb 17 - Feb 18
Charming cottage overlooking Lake Acre

The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.4 out of 10, Exceptional, (28 reviews)
"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"
United States
mike b.
The price is ¥17,179
¥21,444 total
includes taxes & fees
Feb 17 - Feb 18
The Rested Duck Mallard Room

Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake
Miller City
10.0 out of 10, Exceptional, (21 reviews)
"The cabin is perfect for a quiet getaway. Location is great close to Dollar General, gas station and restaurants"
United States
Marsha G.
The price is ¥17,179
¥27,917 total
includes taxes & fees
Feb 18 - Feb 19
Peaceful secluded cabin located near Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
9.8 out of 10, Exceptional, (35 reviews)
"Beautiful place, host was kind and and quick to respond to messages "
United States
Melissa W.
The price is ¥17,179
¥21,444 total
includes taxes & fees
Feb 17 - Feb 18
Cozy cabins on beautiful Horseshoe Lake

The Riverstone Hotel

The Riverstone Hotel
2.5 star property
Charleston
6.8 out of 10, (408 reviews)
"The staff was very friendly and accommodating "
United States
Arturo
The price is ¥10,689
¥11,863 total
includes taxes & fees
Feb 17 - Feb 18
The Riverstone Hotel

Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
The price is ¥18,477
¥44,279 total
includes taxes & fees
Feb 23 - Feb 24
Quiet Country Stay: Modern Home Near Paducah

Charming Home just minutes from Interstate and Mall

Charming Home just minutes from Interstate and Mall
Kevil
10.0 out of 10, Exceptional, (20 reviews)
"We enjoyed staying here very much. Clean and close to where we wanted to be!"
United States
Becky C.
The price is ¥16,797
¥28,576 total
includes taxes & fees
Feb 23 - Feb 24
Charming Home just minutes from Interstate and Mall

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (623 reviews)
"Affordable for a quick one night stay. Restaurant and gas station next to hotel."
United States
Annette
The price is ¥9,482
¥10,524 total
includes taxes & fees
Feb 17 - Feb 18
Super 8 by Wyndham Charleston/Sikeston East MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Cairo Hotel Reviews

Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Cairo?
Let Expedia help you arrange your flight to Cairo, IL (CIR-Cairo Regional) airport or Paducah, KY (PAH-Barkley Regional) airport, and then choose from some places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to find what you need to make your stay special. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Cairo has to offer. Cairo has some interesting things to see and do including Mississippi River and Ohio River Valley, so you might want to take in the local sights during your visit.
When can I expect good weather in Cairo?
Planning for the weather is an important factor for making your trip to Cairo a success, especially when you're splurging. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Cairo is 61 inches.
What's there to see and do in Cairo?
Enjoy all that Cairo has to offer when you visit Mississippi River, Ohio River Valley, and Fort Defiance State Park. If you have spare time during your trip, you might want to make a stop at Mound City National Cemetery and Columbus-Belmont State Park.