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Find All Southern Illinois Hotels
We have found 940 Southern Illinois Hotels
- Rodeway Inn & Suites
- Best Western U. S. Inn
- Holiday Inn Express & Suites Salem, an IHG Hotel
- Seasons Inn & Suites Highland
- Wine Country Farmhouse On the Wine 🍷 Trail! Private Lake kayaks Fire Pit 🔥
- Quality Inn & Suites Salem near I-57
- Days Inn by Wyndham Salem, Illinois
- Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
- Welcome Suites
- The Shelby Inn
- Motel 6 Troy, IL
- Country View Inn & Suites
- Relax Inn
- Super 8 by Wyndham Marshall
- Eighteen-Ninety Sleepover
- First Western Inn
- The Principal Hotel
- Shawnee - Farmhouse on 40 acres: Beautiful Views & Hot Tub!!
- Makanda Inn
- Lighthouse Lodge
- Relax Inn & Suites
- The Turkey Farmhouse just a few minutes from Rend Lake
- The Conner House B&B
Let Expedia take you to the best Hotels in Southern Illinois. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.