A large eye sculpture in a park surrounded by trees.

Find 5 Star Hotels in Northeast Missouri, MO from ￥21,752

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Check availability on Northeast Missouri 5 Star Hotels

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Our top choices for Northeast Missouri 5-star hotels

An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
A modern living room with a sofa, chairs, a coffee table, and a chandelier.
A lobby with a fireplace, two armchairs, a round table, and a bench.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.

1. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
United States
Kennedy
￥91,152
￥106,409 total
includes taxes & fees
Nov 1 - Nov 2
The Ritz-Carlton, St. Louis
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Northeast Missouri.
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

9801 Natural Bridge Road St. Louis MO
￥18,593
￥21,752 total
Oct 18 - Oct 19
includes taxes & fees
8.4/10 Very Good! (1,189 reviews)
Renaissance St. Louis Airport Hotel
21C Museum Hotel St Louis

21C Museum Hotel St Louis

1528 Locust street St. Louis MO
￥22,606
￥27,219 total
Oct 25 - Oct 26
includes taxes & fees
9/10 Wonderful! (2,130 reviews)
21C Museum Hotel St Louis
The Cheshire

The Cheshire

6300 Clayton Rd Richmond Heights MO
￥23,355
￥27,731 total
Oct 18 - Oct 19
includes taxes & fees
The Cheshire
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Learn more about Northeast Missouri

Great live music, sports teams, and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theaters.

See all hotels in Northeast Missouri
A large eye sculpture in a park surrounded by trees.
Photo by Andrew Hershfeld

Top Northeast Missouri Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Northeast Missouri?
You can find a variety of pricing options for 5-star hotels in Northeast Missouri on Expedia. How much you'll pay will depend on when you want to travel, length of stay and other factors. Compare available properties for your chosen dates and make use of our pricing and other filters to score the ideal luxury stay.
  • Search for the lowest price per night from ￥21,752
What makes a hotel 5 stars in Northeast Missouri?
In Northeast Missouri, a hotel must provide a specific level of upscale conveniences to be rated 5 stars. These may include on-site gyms, gourmet restaurants, saunas and spas, premium bedding, complimentary luxury toiletries and more. What also sets 5-star hotels apart is their guest-focused standard of service. You'll enjoy things like concierge services, nightly turn-down services and in-room massage. Some may also offer additional touches like a welcome gift.
Are there any 5-star all-inclusive resorts in Northeast Missouri?
Expedia's filter tool is the easiest way to search for exactly what you're looking for. Select "All inclusive" and "5-star" to see the most upscale hotels in Northeast Missouri where your lodging, meals, activities and entertainment are included in the price. At these escapes, your trip is pure relaxation and indulgence from the moment you check in.

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