Find 4 Star Hotels in Key West, FL from ¥41,899

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Key West 4 Star Hotels

This weekend
Next weekend

Our top choices for Key West 4-star hotels

Blue Flamingo Resort Key West

Blue Flamingo Resort Key West
4.0 star property
New Town
8.0 out of 10, Very Good, (1808)
"the staff was so welcoming and nice, it was a perfect place to stay in Key West!"
United Kingdom
Alicia
The price is ¥36,496
¥49,867 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Blue Flamingo Resort Key West

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses
4.0 star property
Old Town Key West
8.8 out of 10, Excellent, (2959)
"Wonderful stay!"
United States
Elisa
The price is ¥46,228
¥63,457 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Southernmost Beach Resort and Guesthouses

Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa
4.0 star property
Key West Historic District
9.0 out of 10, Wonderful, (1001)
"Staff was courteous and the location is perfect for a weekend in Key West."
United States
TIMOTHY
The price is ¥59,340
¥76,974 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Hyatt Centric Key West Resort and Spa

Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina
4.0 star property
Stock Island
8.8 out of 10, Excellent, (1766)
"The place is great!"
United States
Anna
The price is ¥37,155
¥51,376 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Oceans Edge Key West Resort, Hotel & Marina

Margaritaville Beach House Key West

Margaritaville Beach House Key West
4.0 star property
Key West
8.8 out of 10, Excellent, (1782)
"Nice spot and great staff"
United States
Lindsay Brooke
The price is ¥51,638
¥68,184 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Margaritaville Beach House Key West

The Perry Hotel & Marina Key West

The Perry Hotel & Marina Key West
4.0 star property
Stock Island
9.4 out of 10, Exceptional, (1179)
"great place to stay "
United States
michael
The price is ¥46,930
¥62,483 total
includes taxes & fees
Jan 19 - Jan 20, 2026
The Perry Hotel & Marina Key West

DoubleTree Resort by Hilton Grand Key - Key West

DoubleTree Resort by Hilton Grand Key - Key West
4.0 star property
Key West
8.2 out of 10, Very Good, (1004)
"Nice property, comfortable stay - cookies and staff are great!"
United States
David
The price is ¥38,704
¥48,825 total
includes taxes & fees
Jan 5 - Jan 6, 2026
DoubleTree Resort by Hilton Grand Key - Key West

Parrot Key Hotel & Villas

Parrot Key Hotel & Villas
4.0 star property
Northside Resort
9.0 out of 10, Wonderful, (1220)
"Excellent location, clean rooms, great staff"
United States
Vikas
The price is ¥29,258
¥41,899 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Parrot Key Hotel & Villas

Winslow's Bungalows - Key West Historic Inns

Winslow's Bungalows - Key West Historic Inns
4.0 star property
Old Town Key West
9.2 out of 10, Wonderful, (1096)
"Clean room, quiet location, excellent staff. Breakfast and amenities were great!"
United States
Shannon
The price is ¥56,240
¥71,198 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Winslow's Bungalows - Key West Historic Inns

Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton
4.0 star property
Old Town Key West
8.4 out of 10, Very Good, (490)
"Great place"
United States
ELENA
The price is ¥64,065
¥81,468 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Casa Marina Key West, Curio Collection by Hilton

La Concha Key West, Autograph Collection

La Concha Key West, Autograph Collection
4.0 star property
Key West Historic District
9.0 out of 10, Wonderful, (300)
"Very nice staff! Clean hotel! "
United States
Tabitha Hall
The price is ¥49,163
¥60,592 total
includes taxes & fees
Jan 12 - Jan 13, 2026
La Concha Key West, Autograph Collection

Pier House Resort & Spa

Pier House Resort & Spa
4.0 star property
Key West Historic District
9.0 out of 10, Wonderful, (1013)
"All accommodations were outstanding!"
United States
Bob
Pier House Resort & Spa

The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton
4.0 star property
Old Town Key West
8.6 out of 10, Excellent, (1002)
"Great hotel, great beach, had a really good stay."
United States
Cristian Mihai
The price is ¥51,227
¥67,025 total
includes taxes & fees
Jan 13 - Jan 14, 2026
The Reach Key West, Curio Collection by Hilton

Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
4.0 star property
Old Town Key West
9.2 out of 10, Wonderful, (1029)
"Our stay was great!"
United States
Richard
The price is ¥65,603
¥79,970 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Opal Key Resort & Marina, Key West

The Marker Key West Harbor Resort

The Marker Key West Harbor Resort
4.0 star property
Key West Historic District
9.2 out of 10, Wonderful, (1001)
"Perfect location.. close to the wharf for the best dining experience."
United States
Marty
The price is ¥53,794
¥70,382 total
includes taxes & fees
Jan 14 - Jan 15, 2026
The Marker Key West Harbor Resort

Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
4.0 star property
Key West Historic District
9.2 out of 10, Wonderful, (1004)
"Location, large rooms"
United States
george
The price is ¥69,573
¥90,424 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Ocean Key Resort - A Noble House Resort

Havana Cabana at Key West

Havana Cabana at Key West
4.0 star property
New Town
8.8 out of 10, Excellent, (1710)
"Enjoyed stay, friendly staff and good shuttle bus"
United States
Abdul
The price is ¥35,952
¥51,133 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Havana Cabana at Key West

Santa Maria Suites

Santa Maria Suites
4.0 star property
Old Town Key West
9.6 out of 10, Exceptional, (1001)
"Awesome place we loved it"
United States
Josh
The price is ¥77,303
¥97,533 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Santa Maria Suites

Southernmost House

Southernmost House
4.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1002)
"Great place to stay. Staff was very friendly"
United States
Jacob
The price is ¥57,493
¥79,211 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Southernmost House

Bishop Hotel Key West

Bishop Hotel Key West
4.0 star property
Old Town Key West
9.8 out of 10, Exceptional, (345)
"Very clean rooms, great staff, excellent location. The breakfast each morning was great as was the Happy Hour at their bar."
United States
Jonathan
Bishop Hotel Key West
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Key West

Stroll Duval Street's colorful shops and bars before catching the sunset celebration at Mallory Square with local performers. Explore Hemingway's historic home where six-toed cats roam freely, then snorkel the vibrant coral reefs just offshore.

Top Key West Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Key West?
La Concha Key West is a 4-star hotel in Key West that rates highly among Expedia guests. Beauty services and treatment rooms are a couple of its amenities. Travelers also love Winslows Bungalows. From concierge services to designer toiletries, it features conveniences that cater to all aspects of your relaxation and entertainment.
How much does it cost to stay in a 4-star hotel in Key West?
We can help you easily track down the perfect 4-star hotel for your trip to Key West. Use our handy filter tool to fine-tune your search by things like budget, amenities and hotel star rating and get access to fabulous deals in a few clicks.

  • Search for the lowest price from ¥41,899

What's the difference between 5-star and 4-star hotels in Key West?
Offering a welcoming traveler experience and upscale surroundings, 4-star hotels are a great option for your Key West vacation. These types of stays generally feature lots of handy amenities that make it simple to kick back and relax — think complimentary bathrobes, pools and gyms. Or live in the lap of luxury at a 5-star hotel designed to spoil you with high-end perks and amenities. On-site health clubs, oversized bathrooms and gourmet dining are typically included at these swanky retreats.

Explore a world of travel with Expedia