What's it like in West Main Historic District?

Travelers love the West Main Historic District neighborhood for its beautiful river views, array of dining options, and sporting events. Are you looking for West Main Historic District travel tips? Be sure to check out Frazier International History Museum and Louisville Slugger Museum while you're in the neighborhood.

Where is the best hotel for a stay in West Main Historic District?

Based on our traveler data, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay in West Main Historic District. This hotel is a short 4-minute walk from KFC Yum Center, and it offers a full-service spa and 4 restaurants. Other good choices for your stay in the area include Holiday Inn Express & Suites Louisville Downtown by IHG and Omni Louisville Hotel .

How many hotels will I find in the West Main Historic District area?

If you're searching for places to stay in Louisville, Expedia has something to meet your needs with 234 West Main Historic District hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in West Main Historic District, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to get the best options available in West Main Historic District.

Where can I learn more about changing or cancelling my trip to West Main Historic District?

For more details about picking new dates or cancelling your trip to West Main Historic District, go to https://www.expedia.com/service/ .

What is there to do around this Louisville neighborhood?

For cultural attractions in West Main Historic District, head to Flame Run Glass Studio and Gallery, Frazier International History Museum, and Louisville Slugger Museum. 21c Museum Hotel and Muhammad Ali Center are also a couple of places to visit in the neighborhood. Kentucky Peerless Distilling Co., Louisville Glassworks, and SAR Genealogical Research Library: NSSAR Library are just a few of the places to visit in and around West Main Historic District. While you're out sightseeing, Louisville Science Center and Kentucky Museum of Art and Craft are a couple of additional sights to visit in Louisville.

Top West Main Historic District Hotels

The entrance to the Kentucky Science Center with a large circular structure in the foreground.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for West Main Historic District hotels

A balcony with a view of a river, a bridge, and a cityscape.

1. Galt House Hotel Trademark Collection by Wyndham

West Main Historic District

Shun

￥25,124 total

includes taxes & fees

Nov 8 - Nov 9

A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

2. Embassy Suites Louisville Downtown

West Main Historic District

Frances

￥22,551 total

includes taxes & fees

Nov 23 - Nov 24

A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

3. Omni Louisville Hotel

West Main Historic District

Kristan

￥37,505 total

includes taxes & fees

Nov 16 - Nov 17

A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.

4. Louisville Marriott Downtown

West Main Historic District

Ricardo

￥23,376 total

includes taxes & fees

Nov 26 - Nov 27

A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

5. Homewood Suites by Hilton Louisville Downtown, KY

West Main Historic District

peter

￥21,037 total

includes taxes & fees

Nov 24 - Nov 25

A classical gold statue in front of a multi-story building with large windows and a brick facade.

6. 21c Museum Hotel Louisville

West Main Historic District

Matt

￥28,865 total

includes taxes & fees

Nov 22 - Nov 23

A spacious indoor area with a large dining table, multiple chairs, a fireplace, and a kitchen area with a bar.

7. Cambria Hotel Louisville Downtown-Whiskey Row

West Main Historic District

Sarah

￥17,572 total

includes taxes & fees

Nov 22 - Nov 23

A spacious lobby with a central escalator, seating areas, and modern lighting.

8. Hyatt Regency Louisville

West Main Historic District

Michael Jered

￥23,256 total

includes taxes & fees

Nov 25 - Nov 26

A modern lobby with a central seating area, a reception desk, and a large screen.

9. Holiday Inn Express & Suites Louisville Downtown by IHG

West Main Historic District

evelyn

￥21,041 total

includes taxes & fees

Nov 22 - Nov 23

A cozy living room with a fireplace, a black leather sofa, and a patterned rug.

10. Moxy Louisville Downtown

West Main Historic District

Alicia

￥21,806 total

includes taxes & fees

Nov 15 - Nov 16

A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

11. The Grady

West Main Historic District

Donna

￥27,487 total

includes taxes & fees

Nov 26 - Nov 27

A modern hotel with a prominent 'Aloft Hotels' sign, multiple floors, and a corner location with a view of the city skyline.

12. Aloft by Marriott Louisville Downtown

West Main Historic District

Anthony

￥22,577 total

includes taxes & fees

Nov 23 - Nov 24

A rooftop terrace with seating, a view of the city skyline, and modern architecture.

13. Hilton Garden Inn Louisville Downtown

West Main Historic District

james

￥18,011 total

includes taxes & fees

Nov 23 - Nov 24

A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.

14. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

West Main Historic District

Adrienne Tremonti

￥24,064 total

includes taxes & fees

Nov 23 - Nov 24

A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.

15. Seelbach Hilton Louisville Downtown

West Main Historic District

Leonardo

￥26,320 total

includes taxes & fees

Nov 26 - Nov 27

An outdoor seating area with wicker furniture and a fire pit.

16. Towneplace Suites By Marriott Louisville Downtown

West Main Historic District

Derek

￥19,379 total

includes taxes & fees

Nov 8 - Nov 9

A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.

17. Hotel Distil, Autograph Collection

West Main Historic District

Heather

￥37,195 total

includes taxes & fees

Nov 22 - Nov 23

A Courtyard by Marriott hotel with a modern brick facade, multiple floors, and a prominent sign.

18. Courtyard by Marriott Louisville Downtown

West Main Historic District

Robin

￥20,775 total

includes taxes & fees

Oct 30 - Oct 31

A hotel room with two beds, a TV, and a desk.

19. SpringHill Suites by Marriott Louisville Downtown

West Main Historic District

Kim

￥18,670 total

includes taxes & fees

Nov 22 - Nov 23

A lobby with a reception desk, seating area, and a fireplace.

20. Fairfield Inn & Suites by Marriott Louisville Downtown

West Main Historic District

Eric

￥18,670 total

includes taxes & fees

Oct 27 - Oct 28

View all properties

Compare popular hotels in West Main Historic District

Property	Star rating	Guest rating
Hotel Distil, Autograph Collection	4.0 star property	9.6 Exceptional 512 reviews	View
Homewood Suites by Hilton Louisville Downtown, KY	3.0 star property	9.4 Exceptional 1,004 reviews	View
Omni Louisville Hotel	4.0 star property	9.4 Exceptional 2,207 reviews	View
21c Museum Hotel Louisville	4.5 star property	9.4 Exceptional 1,005 reviews	View
The Grady	4.0 star property	9.4 Exceptional 1,006 reviews	View

Where to stay in West Main Historic District

Find the best West Main Historic District areas and neighborhoods for the activities you enjoy most.

A steamboat docked at a pier with a bridge in the background.

Downtown Louisville

Explore "Museum Row" in the West Main District, catch a game at Louisville Slugger Field, or stroll across the pedestrian-only Big Four Bridge. Enjoy diverse attractions, restaurants, and the Louie Link skywalk.

See properties

A nighttime cityscape with a brightly lit bridge and a skyline featuring a prominent dome-shaped building.

St. Matthews

Major shopping destination with the fifth-largest mall in Kentucky, Mall St. Matthews, and smaller centers along Shelbyville Road. Don't miss the historic St. Matthew's Episcopal Church and Holy Trinity.

See properties

A historical marker for the Conrad-Caldwell House, detailing its architectural style and history.

Old Louisville

Boasting Victorian architecture and the highest concentration of stained glass windows in residential homes, Old Louisville offers a walkable neighborhood with pedestrian-only streets, diverse dining options, and attractions like Central Park and the Conrad-Caldwell House.

See properties

A nighttime hot air balloon festival with colorful balloons, including one labeled "OLIVER WINERY."

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

See properties

A city skyline at dusk with illuminated buildings reflecting on the water.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

See properties

Top West Main Historic District Hotel Reviews

Fairfield Inn & Suites by Marriott Louisville Downtown

10/10 Excellent

"We stayed here while attending a comedy show at the Yum Center. Great walking destinations to the Yum Center, 4th Street Live and additional restaurants, and reasonably priced."

21c Museum Hotel Louisville

10/10 Excellent

"Upscale, interesting hotel in a great location in downtown Louisville. Quiet, with a comfortable bed and large bathroom. Large bottles of drinking water provided at no extra charge in the room. Staff was super helpful in recommending a nearby cafe for espresso and pastries in the morning. Valet parking was $35 - but that's typical for downtown hotels."

Find hotels in West Main Historic District, Louisville

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for West Main Historic District hotels

1. Galt House Hotel Trademark Collection by Wyndham

2. Embassy Suites Louisville Downtown

3. Omni Louisville Hotel

4. Louisville Marriott Downtown

5. Homewood Suites by Hilton Louisville Downtown, KY

6. 21c Museum Hotel Louisville

7. Cambria Hotel Louisville Downtown-Whiskey Row

8. Hyatt Regency Louisville

9. Holiday Inn Express & Suites Louisville Downtown by IHG

10. Moxy Louisville Downtown

11. The Grady

12. Aloft by Marriott Louisville Downtown

13. Hilton Garden Inn Louisville Downtown

14. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

15. Seelbach Hilton Louisville Downtown

16. Towneplace Suites By Marriott Louisville Downtown

17. Hotel Distil, Autograph Collection

18. Courtyard by Marriott Louisville Downtown

19. SpringHill Suites by Marriott Louisville Downtown

20. Fairfield Inn & Suites by Marriott Louisville Downtown

Compare popular hotels in West Main Historic District

Where to stay in West Main Historic District

Downtown Louisville

St. Matthews

Old Louisville

Fairgrounds

Jeffersontown

Top West Main Historic District Hotel Reviews

Fairfield Inn & Suites by Marriott Louisville Downtown

Frequently asked questions

Explore a world of travel with Expedia