The entrance to the Kentucky Science Center with a large circular structure in the foreground.

Find hotels in West Main Historic District, Louisville

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for West Main Historic District hotels

1. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (4,413 reviews)
"Great place to stay!"
United States
Judy
The price is ¥21,334
¥25,100 total
includes taxes & fees
Nov 8 - Nov 9
Galt House Hotel Trademark Collection by Wyndham

2. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,384 reviews)
"Excellent stay"
United States
Frances
The price is ¥19,149
¥22,532 total
includes taxes & fees
Nov 23 - Nov 24
Embassy Suites Louisville Downtown

3. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (2,203 reviews)
"Beautiful Hotel"
United States
Kristan
The price is ¥31,847
¥37,472 total
includes taxes & fees
Nov 16 - Nov 17
Omni Louisville Hotel

4. Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,006 reviews)
"A clean and well appointed hotel in excellent location."
United States
Ricardo
The price is ¥26,284
¥30,925 total
includes taxes & fees
Nov 22 - Nov 23
Louisville Marriott Downtown

5. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,002 reviews)
"Staff very friendly"
United States
peter
The price is ¥18,064
¥21,254 total
includes taxes & fees
Nov 24 - Nov 25
Homewood Suites by Hilton Louisville Downtown, KY

6. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1,003 reviews)
"Great clean hotel awesome staff."
United States
Anthony
The price is ¥19,184
¥22,572 total
includes taxes & fees
Nov 8 - Nov 9
Aloft by Marriott Louisville Downtown

7. Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,002 reviews)
"amazing location will definitely be back"
United States
Michael Jered
The price is ¥19,922
¥23,440 total
includes taxes & fees
Nov 23 - Nov 24
Hyatt Regency Louisville

8. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,002 reviews)
"It was a great stay! The room and location were perfect, and the staff were very accommodating!"
United States
Matt
The price is ¥23,845
¥28,841 total
includes taxes & fees
Nov 22 - Nov 23
21c Museum Hotel Louisville

9. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1,005 reviews)
"Location was perfect and staff was very friendly."
United States
Sarah
The price is ¥14,921
¥17,557 total
includes taxes & fees
Nov 22 - Nov 23
Cambria Hotel Louisville Downtown-Whiskey Row

10. Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
West Main Historic District
8.8 out of 10, Excellent, (1,839 reviews)
"Loved the area and the staff"
United States
evelyn
The price is ¥18,494
¥21,761 total
includes taxes & fees
Nov 17 - Nov 18
Holiday Inn Express & Suites Louisville Downtown by IHG

11. Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
West Main Historic District
9.2 out of 10, Wonderful, (855 reviews)
"Loved the location and street parking options…"
United States
Alicia
The price is ¥18,517
¥21,786 total
includes taxes & fees
Nov 15 - Nov 16
Moxy Louisville Downtown

12. The Grady

The Grady
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,000 reviews)
"I really enjoyed my stay and hope to return soon."
United States
Donna
The price is ¥24,409
¥28,720 total
includes taxes & fees
Nov 15 - Nov 16
The Grady

13. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (812 reviews)
"great breakfast"
United States
Derek
The price is ¥16,457
¥19,364 total
includes taxes & fees
Nov 8 - Nov 9
Towneplace Suites By Marriott Louisville Downtown

14. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,001 reviews)
"Clean room and nice gym"
United States
Angel
The price is ¥22,836
¥26,868 total
includes taxes & fees
Nov 23 - Nov 24
Seelbach Hilton Louisville Downtown

15. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (166 reviews)
"Incredibly lovely location"
United States
Cameron
The price is ¥20,434
¥24,043 total
includes taxes & fees
Nov 23 - Nov 24
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

16. Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown
3.5 star property
West Main Historic District
8.4 out of 10, Very good, (1,007 reviews)
"Excellent location if seeing a concert at the Palace."
United States
james
The price is ¥15,307
¥18,011 total
includes taxes & fees
Nov 23 - Nov 24
Hilton Garden Inn Louisville Downtown

17. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
West Main Historic District
9.6 out of 10, Exceptional, (512 reviews)
"The room exceeded expectations! All of the restaurants had exceptional food! Beautiful hotel, great location, and very friendly staff!"
United States
Heather
The price is ¥31,584
¥37,162 total
includes taxes & fees
Nov 22 - Nov 23
Hotel Distil, Autograph Collection

18. SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.6 out of 10, Excellent, (1,001 reviews)
"Great location. Clean rooms. Nice staff."
United States
Kim
The price is ¥15,853
¥18,654 total
includes taxes & fees
Nov 22 - Nov 23
SpringHill Suites by Marriott Louisville Downtown

19. Courtyard by Marriott Louisville Downtown

Courtyard by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.6 out of 10, Excellent, (1,001 reviews)
"The hotel room was clean and spacious. Nice big TV. Road noise was a bit much late at night, but the white noise machine and ear plugs helped."
United States
Robin
The price is ¥17,642
¥20,758 total
includes taxes & fees
Oct 31 - Nov 1
Courtyard by Marriott Louisville Downtown

20. Hampton Inn Louisville Downtown

Hampton Inn Louisville Downtown
2.5 star property
West Main Historic District
8.4 out of 10, Very good, (1,000 reviews)
"Clean room, great staff, and immensities was wonderful"
United States
LaShanda
The price is ¥15,389
¥18,107 total
includes taxes & fees
Oct 30 - Oct 31
Hampton Inn Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in West Main Historic District

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
512 reviews
View
A classical gold statue in front of a multi-story building with large windows and a brick facade.
21c Museum Hotel Louisville
4.5 star property
9.4
Exceptional
1,002 reviews
View
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
Omni Louisville Hotel
4.0 star property
9.4
Exceptional
2,203 reviews
View
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
The Grady
4.0 star property
9.4
Exceptional
1,000 reviews
View
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
9.4
Exceptional
166 reviews
View

Where to stay in West Main Historic District

Find the best West Main Historic District areas and neighborhoods for the activities you enjoy most.

Downtown Louisville

Explore "Museum Row" in the West Main District, catch a game at Louisville Slugger Field, or stroll across the pedestrian-only Big Four Bridge. Enjoy diverse attractions, restaurants, and the Louie Link skywalk.

St. Matthews

Major shopping destination with the fifth-largest mall in Kentucky, Mall St. Matthews, and smaller centers along Shelbyville Road. Don't miss the historic St. Matthew's Episcopal Church and Holy Trinity.

Old Louisville

Boasting Victorian architecture and the highest concentration of stained glass windows in residential homes, Old Louisville offers a walkable neighborhood with pedestrian-only streets, diverse dining options, and attractions like Central Park and the Conrad-Caldwell House.

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

Top West Main Historic District Hotel Reviews

Frequently asked questions

What's it like in West Main Historic District?
Travelers love the West Main Historic District neighborhood for its beautiful river views, array of dining options, and sporting events. Are you looking for West Main Historic District travel tips? Be sure to check out Frazier International History Museum and Louisville Slugger Museum while you're in the neighborhood.
Where is the best hotel for a stay in West Main Historic District?
Based on our traveler data, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay in West Main Historic District. This hotel is a short 4-minute walk from KFC Yum Center, and it offers a full-service spa and 4 restaurants. Other good choices for your stay in the area include Holiday Inn Express & Suites Louisville Downtown by IHG and Omni Louisville Hotel.
How many hotels will I find in the West Main Historic District area?
If you're searching for places to stay in Louisville, Expedia has something to meet your needs with 234 West Main Historic District hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in West Main Historic District, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to get the best options available in West Main Historic District.
Where can I learn more about changing or cancelling my trip to West Main Historic District?
For more details about picking new dates or cancelling your trip to West Main Historic District, go to https://www.expedia.com/service/.
What is there to do around this Louisville neighborhood?
For cultural attractions in West Main Historic District, head to Flame Run Glass Studio and Gallery, Frazier International History Museum, and Louisville Slugger Museum. 21c Museum Hotel and Muhammad Ali Center are also a couple of places to visit in the neighborhood. Kentucky Peerless Distilling Co., Louisville Glassworks, and SAR Genealogical Research Library: NSSAR Library are just a few of the places to visit in and around West Main Historic District. While you're out sightseeing, Louisville Science Center and Kentucky Museum of Art and Craft are a couple of additional sights to visit in Louisville.

Explore a world of travel with Expedia