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Oct 17 - Oct 18
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Oct 18 - Oct 19
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Our top choices for 21c Museum Hotel hotels

A wooden staircase with a balustrade leading to a landing.
A bedroom with a bed, a dresser, a television, and a desk with a lamp.
A brick building with a covered porch, columns, and potted plants.
A two-story brick building with a white porch and a sign reading "Hotel".

1. Market Street Inn

Market Street Inn
2.1 km from 21c Museum Hotel
United States
Holly
￥34,943
￥39,486 total
includes taxes & fees
Oct 18 - Oct 19
Market Street Inn
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
A bar with shelves of liquor bottles and a bartender preparing drinks.
A modern living room with a leather sectional sofa, a glass coffee table, and a view of the city skyline through large windows.
An outdoor dining area with tables and chairs, a green building facade, and a row of plants along the wall.

2. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville, 0.8 km from 21c Museum Hotel
United States
Heather
￥36,016
￥42,376 total
includes taxes & fees
Nov 8 - Nov 9
Hotel Distil, Autograph Collection
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.
An outdoor patio with red furniture, including a table and chairs, and two red umbrellas providing shade.
A room with a red velvet sofa, a blue armchair, and a small round table with books.
A room with a large mirror, a wooden dresser, a red patterned rug, and a door with a wreath.

3. DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
Old Louisville, 2.8 km from 21c Museum Hotel
United States
Casey
￥23,892
￥27,731 total
includes taxes & fees
Oct 18 - Oct 19
DuPont Mansion Bed & Breakfast
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
A spacious hotel lobby with a central seating area, stone accent walls, and a chandelier.
A swimming pool with lounge chairs and a view of the city.
A modern hotel with multiple floors, large windows, and a prominent sign for Homewood Suites.

4. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
Downtown Louisville, 0.1 km from 21c Museum Hotel
United States
Kelly
￥19,150
￥22,531 total
includes taxes & fees
Nov 8 - Nov 9
Homewood Suites by Hilton Louisville Downtown, KY
A grand lobby with ornate columns, plush seating, and a chandelier.
A grand lobby with ornate ceiling, multiple seating areas, and a staircase.
A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".
A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.

5. The Brown Hotel

The Brown Hotel
Downtown Louisville, 1.2 km from 21c Museum Hotel
United States
John
￥19,800
￥23,297 total
includes taxes & fees
Oct 18 - Oct 19
The Brown Hotel
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A modern interior with a fireplace, bookshelves, and seating areas.
A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.
A modern building entrance with a glass facade, wooden ceiling, and illuminated fixtures.

6. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville, 0.8 km from 21c Museum Hotel
United States
Samantha
￥20,765
￥24,431 total
includes taxes & fees
Oct 30 - Oct 31
Omni Louisville Hotel
An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.
A modern hotel lobby with a brick wall, grey sofas, a coffee table, and a large TV screen displaying "TEMPO by Hilton".
A modern hotel lobby with a reception desk, seating area, and a large abstract ceiling artwork.
A modern hotel room with a large bed, a desk with a chair, a flat-screen TV, and a large window offering a city view.

7. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
Phoenix Hill, 2 km from 21c Museum Hotel
United States
Addison
￥19,317
￥22,729 total
includes taxes & fees
Oct 25 - Oct 26
Tempo By Hilton Louisville Downtown Nulu
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
A modern restaurant interior with a staircase, round tables, and a brick wall.
A building with a sign reading "THE GRADY" at the entrance.
A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".

8. The Grady

The Grady
Downtown Louisville, 0.1 km from 21c Museum Hotel
United States
Donna
￥21,698
￥25,530 total
includes taxes & fees
Oct 18 - Oct 19
The Grady
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.
A modern interior with a green wall, black chairs, and a ceiling with exposed beams and lights.
A modern, well-lit room with a large bed, a green sofa, a small round table, and a kitchen area in the background.
A modern bedroom with a bed, a blue sofa, a large rug, and a TV on the wall.

9. Stellar Suites

Stellar Suites
East Market District, 2.2 km from 21c Museum Hotel
United States
Kevin
￥15,474
￥26,214 total
includes taxes & fees
Nov 16 - Nov 17
Stellar Suites
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.
A modern hotel room with a large bed, a city view, and a unique headboard design.
A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.

10. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville, 0.8 km from 21c Museum Hotel
United States
Cameron
￥28,377
￥33,389 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A classical gold statue in front of a multi-story building with large windows and a brick facade.
A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.
A steam fountain in a brick alleyway.

11. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville, < 0.1 km from 21c Museum Hotel
United States
Matt
￥24,041
￥29,076 total
includes taxes & fees
Nov 8 - Nov 9
21c Museum Hotel Louisville
An outdoor seating area with wicker furniture and a fire pit.
A modern lounge area with seating, tables, and a view of the city through large windows.
A modern living room with a sofa, armchairs, a coffee table, and a TV.
A modern hotel lobby with a large central table, multiple seating areas, and large windows offering city views.

12. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
Downtown Louisville, 0.3 km from 21c Museum Hotel
United States
Barbara
￥15,328
￥18,035 total
includes taxes & fees
Nov 8 - Nov 9
Towneplace Suites By Marriott Louisville Downtown
A modern bar area with a circular bar, multiple seating options, and a large screen.
A modern living room with a sectional sofa, a small table, and a floor lamp. Large windows offer a view of a cityscape and a building with glass windows.
A spacious indoor area with a large dining table, multiple chairs, a fireplace, and a kitchen area with a bar.
A modern interior with a central wooden table, refrigerated beverage dispensers, and shelves stocked with snacks and condiments.

13. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
Downtown Louisville, 1.2 km from 21c Museum Hotel
United States
Sarah
￥15,965
￥18,783 total
includes taxes & fees
Oct 25 - Oct 26
Cambria Hotel Louisville Downtown-Whiskey Row
A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.
A modern hotel with a prominent 'Marriott' sign, large windows, and a brick facade.
A modern hotel room with a large bed, a desk with a chair, a TV mounted on the wall, and a window with a city view.
A cozy living room with a fireplace, a black leather sofa, and a patterned rug.

14. Moxy Louisville Downtown

Moxy Louisville Downtown
Downtown Louisville, 0.9 km from 21c Museum Hotel
United States
Alicia
￥13,186
￥15,514 total
includes taxes & fees
Nov 15 - Nov 16
Moxy Louisville Downtown
An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.
A modern hotel with a prominent 'Aloft Hotels' sign, multiple floors, and a corner location with a view of the city skyline.
A modern bar area with sofas, tables, and a bar stocked with bottles.
A modern coffee shop interior with a central island, wooden counter, and large windows.

15. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
Downtown Louisville, 0.9 km from 21c Museum Hotel
United States
Dolores
￥14,608
￥17,189 total
includes taxes & fees
Oct 25 - Oct 26
Aloft by Marriott Louisville Downtown
A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.
A modern hotel building with a prominent AC Hotel NULU sign, multiple floors, and a well-lit entrance.
A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.
A modern restaurant with high ceilings, large windows, and a mix of round and rectangular tables.

16. AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
East Market District, 2 km from 21c Museum Hotel
United States
Jen
￥22,613
￥26,606 total
includes taxes & fees
Oct 25 - Oct 26
AC Hotel Louisville Downtown
A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.
A bedroom with a bed, a chair, a TV, and a window with curtains.
A yellow coffee shop counter with a menu board above, displaying various coffee and food items.
A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.

17. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
East Market District, 2 km from 21c Museum Hotel
United States
Tyler
￥21,333
￥25,102 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Genevieve part of JdV by Hyatt
A covered patio with a stone wall, a glass table, and a bench.
A garden pathway with a lantern, potted plants, and a white fence.
A grand room with a fireplace, a staircase, and a chandelier.
Staircase

18. Central Park Bed & Breakfast

Central Park Bed & Breakfast
Old Louisville, 2.9 km from 21c Museum Hotel
United States
Nicole
￥24,018
￥27,878 total
includes taxes & fees
Oct 25 - Oct 26
Central Park Bed & Breakfast
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.
A balcony with a view of a river, a bridge, and a cityscape.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.

19. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville, 0.5 km from 21c Museum Hotel
United States
Scott w
￥22,156
￥26,070 total
includes taxes & fees
Nov 8 - Nov 9
Galt House Hotel Trademark Collection by Wyndham
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.
A hotel dining area with long tables, booths, and a bar.
An indoor swimming pool with clear water, surrounded by white marble walls and columns, and furnished with lounge chairs and tables.
A modern hotel room with a living area, a dining area, and a bedroom.

20. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
Downtown Louisville, 0.8 km from 21c Museum Hotel
United States
Frances
￥21,232
￥24,982 total
includes taxes & fees
Nov 15 - Nov 16
Embassy Suites Louisville Downtown
View all properties

Compare popular hotels close to 21c Museum Hotel

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A wooden staircase with a balustrade leading to a landing.
Market Street Inn
9.8
Exceptional
125 reviews
View
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
Hotel Distil, Autograph Collection
9.6
Exceptional
510 reviews
View
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.
DuPont Mansion Bed & Breakfast
9.6
Exceptional
150 reviews
View
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
Homewood Suites by Hilton Louisville Downtown, KY
9.4
Exceptional
1,002 reviews
View
A grand lobby with ornate columns, plush seating, and a chandelier.
The Brown Hotel
9.4
Exceptional
1,388 reviews
View

Top 21c Museum Hotel Hotel Reviews

Hyatt Regency Louisville

Hyatt Regency Louisville

10/10 Excellent
"amazing location will definitely be back"
Michael Jered 2-night trip
Posted 13 hours ago
Hyatt Regency Louisville
21c Museum Hotel Louisville

21c Museum Hotel Louisville

10/10 Excellent
"Unique hotel with character. There's a museum inside and they provide you with a free bourbon sample to tour it. And the PENGUINS. Everywhere there are 3' tall red plastic penguins that seem to move around the hotel. What a fun idea. Woke up to one in front of our door one morning. Great staff!!! So helpful and great to talk to. Everyone from the doorman to the front desk and bar staff. Also loved the bar! Cici was amazing!"
Chris 5-night trip
Posted 18 hours ago
21c Museum Hotel Louisville
The Brown Hotel

The Brown Hotel

10/10 Excellent
"Stay frequently. Just make sure to make reservations in the dining room incl breakfast or call room service."
Katherine 2-night trip
Posted 19 hours ago
The Brown Hotel
Moxy Louisville Downtown

Moxy Louisville Downtown

10/10 Excellent
"I had a nice stay and would recommend staying here"
Richard 1-night trip
Posted 21 hours ago
Moxy Louisville Downtown
The Grady

The Grady

10/10 Excellent
"The location, history and ambience were wonderful."
Debbie 5-night trip
Posted 2 days ago
The Grady
Louisville Marriott Downtown

Louisville Marriott Downtown

8/10 Good
"room was very clean but the there were additional blankets provided"
Mary Francis 2-night trip
Posted 4 days ago
Louisville Marriott Downtown
Suite 7 City Loft Escape with River Views! By Hollyhock

Suite 7 City Loft Escape with River Views! By Hollyhock

10/10 Excellent
"Great location- super responsive host - clean and great view of the river."
Jim M. 3-night trip
Posted 3 weeks ago
Suite 7 City Loft Escape with River Views! By Hollyhock
The PRES@The 713! Penthouse Suite with private rooftop patio, on Bourbon Trail!

The PRES@The 713! Penthouse Suite with private rooftop patio, on Bourbon Trail!

10/10 Excellent
"Wonderful experience from making the reservation until the end of our stay. Great communication with the hosts. And enjoyed the location and the loft was very comfortable."
Jill P. 2-night trip
Posted 2 months ago
The PRES@The 713! Penthouse Suite with private rooftop patio, on Bourbon Trail!
Bluegrass River View! Soak & Savor by Hollyhock

Bluegrass River View! Soak & Savor by Hollyhock

10/10 Excellent
"Thank you for hosting us. Our boys basketball team used this as home base with 2 dad's and 4 kids staying here. Everyone had a blast and enjoyed the view."
Heather A. 4-night trip
Posted 3 months ago
Bluegrass River View! Soak & Savor by Hollyhock

Other attractions near 21c Museum Hotel

A historic building with ornate architecture, including columns and decorative moldings.

Louisville Science Center

7.8/10 (6 reviews)
Science is all around us, inescapable. Understand important elements of our world with a visit to this science center for all ages.
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The Kentucky Center for the Performing Arts building facade with large glass windows and a prominent sign.

Kentucky Center for the Performing Arts

8.8/10 (49 reviews)
Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.
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A modern building with a cylindrical structure and a glass facade.

Muhammad Ali Center

8.8/10 (295 reviews)
One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.
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A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.
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Golden Statue of David

Find out about the history of Louisville when you take a trip to Golden Statue of David. Attend a sporting event or simply enjoy the lively bars while you're in the area.
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Kentucky Museum of Art and Craft

You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your travels in Louisville. Stroll along the area's riverfront or experience its lively festivals.
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Evan Williams Bourbon Experience

8.6/10 (20 reviews)
You can take time to visit Evan Williams Bourbon Experience during your travels to Louisville. Attend a sporting event or simply enjoy the lively bars while you're in the area.
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SAR Genealogical Research Library: NSSAR Library

You can spend an afternoon browsing the exhibits at SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants.
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Frequently asked questions

What's the area like around 21c Museum Hotel?
21c Museum Hotel is located in a family-friendly area of Louisville known for its beautiful river views and great live music scene. If you're looking for a convenient place to stay, check out the 292 hotels and other accommodations you'll find within a mile.
What's the best place to stay near 21c Museum Hotel?
Adjacent to 21c Museum Hotel, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and 4 restaurants. Other good choices within a short distance include Holiday Inn Express & Suites Louisville Downtown by IHG and Omni Louisville Hotel.
How many hotels will I find close to 21c Museum Hotel?
Expedia has 292 hotels and other accommodations within a mile from 21c Museum Hotel.
If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals near 21c Museum Hotel.
Where can I learn more about changing or cancelling my trip in the area near 21c Museum Hotel?
For additional details about updating your stay near 21c Museum Hotel or cancelling it, click here.
What can I see and do near 21c Museum Hotel?
You might want to spend some time browsing the exhibits at Muhammad Ali Center, Louisville Slugger Museum, or Frazier International History Museum. Explore landmarks like Belle of Louisville, Whiskey Row, and Big Four Bridge. You can watch performances at Louisville Palace, Derby Dinner Playhouse, and Headliners Music Hall if you're interested in local theater.

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