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Sep 29 - Sep 30
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Sep 30 - Oct 1
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Oct 2 - Oct 4
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Oct 9 - Oct 11

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Our top choices for 21c Museum Hotel hotels

A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.
A covered outdoor seating area with wicker furniture and a wooden railing.
A spacious dining area with a chandelier, a fireplace, and a view of greenery outside.
A building entrance with a dark door, a large number '1332' above it, and two large potted ferns on either side.

1. Louisville Bourbon Inn

Louisville Bourbon Inn
Old Louisville, 2.8 km from 21c Museum Hotel
United States
Roy
￥43,917
￥50,974 total
includes taxes & fees
Oct 5 - Oct 6
Louisville Bourbon Inn
A wooden staircase with a balustrade leading to a landing.
A dining area with brick walls, wooden shelves, and tables set for a meal.
A two-story brick building with a white porch and a sign reading "Hotel".
A bedroom with a bed, a dresser, a television, and a desk with a lamp.

2. Market Street Inn

Market Street Inn
2.1 km from 21c Museum Hotel
United States
Holly
￥30,793
￥34,796 total
includes taxes & fees
Sep 30 - Oct 1
Market Street Inn
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.
An outdoor patio with red furniture, including a table and chairs, and two red umbrellas providing shade.
A room with a large mirror, a wooden dresser, a red patterned rug, and a door with a wreath.
A living room with a sofa, a fireplace, a staircase, and a chandelier.

3. DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
Old Louisville, 2.8 km from 21c Museum Hotel
United States
Casey
￥28,674
￥33,283 total
includes taxes & fees
Sep 30 - Oct 1
DuPont Mansion Bed & Breakfast
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
A spacious hotel lobby with a central seating area, stone accent walls, and a chandelier.
A swimming pool with lounge chairs and a view of the city.
A modern hotel with multiple floors, large windows, and a prominent sign for Homewood Suites.

4. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
Downtown Louisville, 0.1 km from 21c Museum Hotel
United States
Kelly
￥18,903
￥22,242 total
includes taxes & fees
Oct 25 - Oct 26
Homewood Suites by Hilton Louisville Downtown, KY
A grand lobby with ornate columns, plush seating, and a chandelier.
A grand lobby with ornate ceiling, multiple seating areas, and a staircase.
A grand lobby with ornate ceiling, large windows, and classic furniture.
A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".

5. The Brown Hotel

The Brown Hotel
Downtown Louisville, 1.2 km from 21c Museum Hotel
United States
Meghan
￥21,132
￥24,863 total
includes taxes & fees
Oct 29 - Oct 30
The Brown Hotel
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.
A modern interior with a green wall, black chairs, and a ceiling with exposed beams and lights.
A modern bedroom with a bed, a blue sofa, a large rug, and a TV on the wall.
A modern KFC building with large glass windows, a prominent sign, and a well-lit entrance area.

6. Stellar Suites

Stellar Suites
East Market District, 2.2 km from 21c Museum Hotel
United States
Kevin
￥15,464
￥26,166 total
includes taxes & fees
Oct 18 - Oct 19
Stellar Suites
An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.
A modern hotel lobby with a brick wall, grey sofas, a coffee table, and a large TV screen displaying "TEMPO by Hilton".
A modern restaurant with high tables and booths, wooden ceiling panels, and framed pictures on the walls.
A modern hotel room with a large bed, a desk with a chair, a flat-screen TV, and a large window offering a city view.

7. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
Phoenix Hill, 2 km from 21c Museum Hotel
United States
Addison
￥19,232
￥22,629 total
includes taxes & fees
Oct 4 - Oct 5
Tempo By Hilton Louisville Downtown Nulu
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A lobby with a marble floor, a reception desk, and a large chandelier.
A modern building entrance with a glass facade, wooden ceiling, and illuminated fixtures.
A modern interior with a fireplace, bookshelves, and seating areas.

8. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville, 0.8 km from 21c Museum Hotel
United States
Travis
￥31,986
￥37,636 total
includes taxes & fees
Oct 30 - Oct 31
Omni Louisville Hotel
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".
A building with a sign reading "THE GRADY" at the entrance.
A modern hotel room with a large bed, a desk with a flat-screen TV, a green armchair, and a view of the city through large windows.

9. The Grady

The Grady
Downtown Louisville, 0.1 km from 21c Museum Hotel
United States
Bruce
￥27,035
￥31,811 total
includes taxes & fees
Oct 4 - Oct 5
The Grady
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.
A modern hotel room with a large bed, a city view, and a unique headboard design.
A modern lobby with a central reception desk, seating area, and a large abstract wall art piece.
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.

10. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville, 0.8 km from 21c Museum Hotel
United States
Cameron
￥33,431
￥39,336 total
includes taxes & fees
Oct 11 - Oct 12
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A classical gold statue in front of a multi-story building with large windows and a brick facade.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.
A steam fountain in a brick alleyway.
A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.

11. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville, < 0.1 km from 21c Museum Hotel
United States
Matt
￥26,624
￥32,112 total
includes taxes & fees
Oct 25 - Oct 26
21c Museum Hotel Louisville
An outdoor seating area with wicker furniture and a fire pit.
An indoor swimming pool with clear water, a diving board, and lounge chairs around the pool area.
A modern hotel lobby with a large central table, multiple seating areas, and large windows offering city views.
A modern living room with a sofa, armchairs, a coffee table, and a TV.

12. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
Downtown Louisville, 0.3 km from 21c Museum Hotel
United States
Scott
￥17,301
￥20,355 total
includes taxes & fees
Oct 25 - Oct 26
Towneplace Suites By Marriott Louisville Downtown
A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.
A yellow coffee shop counter with a menu board above, displaying various coffee and food items.
A brightly lit grocery store with yellow shelving and a central checkout counter.
A bedroom with a bed, a chair, a TV, and a window with curtains.

13. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
East Market District, 2 km from 21c Museum Hotel
United States
Tyler
￥23,942
￥28,172 total
includes taxes & fees
Oct 26 - Oct 27
Hotel Genevieve part of JdV by Hyatt
A covered patio with a stone wall, a glass table, and a bench.
A stone house with a balcony, a front door, and a staircase leading to the entrance.
Staircase
A garden pathway with a lantern, potted plants, and a white fence.

14. Central Park Bed & Breakfast

Central Park Bed & Breakfast
Old Louisville, 2.9 km from 21c Museum Hotel
United States
Brittany
￥24,731
￥28,705 total
includes taxes & fees
Oct 5 - Oct 6
Central Park Bed & Breakfast
A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.
A modern interior with a central seating area, a television screen, and a wooden partition with various items displayed.
A modern hotel building with a prominent AC Hotel NULU sign, multiple floors, and a well-lit entrance.
A modern restaurant with high ceilings, large windows, and a mix of round and rectangular tables.

15. AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
East Market District, 2 km from 21c Museum Hotel
United States
Jen
￥22,525
￥26,503 total
includes taxes & fees
Oct 25 - Oct 26
AC Hotel Louisville Downtown
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A balcony with a view of a river, a bridge, and a cityscape.
A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.

16. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville, 0.5 km from 21c Museum Hotel
United States
Saud
￥23,655
￥27,832 total
includes taxes & fees
Oct 28 - Oct 29
Galt House Hotel Trademark Collection by Wyndham
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.
An indoor swimming pool with clear water, surrounded by white marble walls and columns, and furnished with lounge chairs and tables.
A hotel dining area with long tables, booths, and a bar.
A modern hotel room with a living area, a dining area, and a bedroom.

17. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
Downtown Louisville, 0.8 km from 21c Museum Hotel
United States
Maurica
￥20,652
￥24,298 total
includes taxes & fees
Oct 29 - Oct 30
Embassy Suites Louisville Downtown
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.
A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.
A modern bar area with glass partitions, bar stools, and a variety of bottles.
A reception area with marble counters, modern pendant lighting, and potted orchids.

18. Louisville Marriott Downtown

Louisville Marriott Downtown
Downtown Louisville, 0.7 km from 21c Museum Hotel
United States
Jacobi
￥33,708
￥39,661 total
includes taxes & fees
Oct 12 - Oct 13
Louisville Marriott Downtown
Lobby sitting area
A modern interior with a curved wall featuring vertical lines and geometric patterns.
A modern lobby with a curved seating area, a red ottoman, and a television screen.
A modern dining area with blue and red seating, wooden tables, and decorative hanging lamps.

19. Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
Downtown Louisville, 0.3 km from 21c Museum Hotel
United States
Kenneth
￥16,514
￥19,431 total
includes taxes & fees
Oct 25 - Oct 26
Holiday Inn Express & Suites Louisville Downtown by IHG
A spacious lobby with a central escalator, comfortable seating areas, and modern lighting fixtures.
A modern living room with a sofa, armchairs, a coffee table, and a dining area with a table and chairs.
A modern hotel exterior with outdoor seating, a glass canopy, and a visible sign for the Hyatt Regency.
A modern lobby with a central seating area, an escalator, and a staircase.

20. Hyatt Regency Louisville

Hyatt Regency Louisville
Downtown Louisville, 0.6 km from 21c Museum Hotel
United States
Lester
￥25,343
￥29,819 total
includes taxes & fees
Oct 29 - Oct 30
Hyatt Regency Louisville
View all properties

Compare popular hotels close to 21c Museum Hotel

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.
Louisville Bourbon Inn
10.0
Exceptional
25 reviews
View
A wooden staircase with a balustrade leading to a landing.
Market Street Inn
9.8
Exceptional
125 reviews
View
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.
DuPont Mansion Bed & Breakfast
9.6
Exceptional
147 reviews
View
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
Homewood Suites by Hilton Louisville Downtown, KY
9.4
Exceptional
1,007 reviews
View
A grand lobby with ornate columns, plush seating, and a chandelier.
The Brown Hotel
9.4
Exceptional
1,334 reviews
View

Top 21c Museum Hotel Hotel Reviews

The Brown Hotel

The Brown Hotel

10/10 Excellent
"Room was clean and all of the staff from front desk to valet were amazing."
Stephanie 1-night trip
Posted less than an hour ago
The Brown Hotel
Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG

8/10 Good
"Right off a major interstate. Within walking distance of many distilleries, museums and restaurants. Rooms were clean and staff very helpful. Breakfast was good but no rotation."
Frederick 4-night trip
Posted less than an hour ago
Holiday Inn Express & Suites Louisville Downtown by IHG
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

8/10 Good
"We love the Galt House. Would recommended for sure. It is central to everything and easy to access to everything."
Samantha 4-night trip
Posted 15 hours ago
Galt House Hotel Trademark Collection by Wyndham
Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row

10/10 Excellent
"Staff was friendly and the room was clean!"
Sara 2-night trip
Posted 22 hours ago
Cambria Hotel Louisville Downtown-Whiskey Row
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

10/10 Excellent
"The rooms are nice, with very high ceilings, making them bright and open. The breakfast was very good, but the unyielding shut-off of breakfast time was off-putting at best and quite wasteful with full trays of buffet food made inaccessible immediately as the breakfast timeframe closed. The spirit Shirley is not reasonably staffed or scheduled to be reliable and helpful. The wait and communication on the arrival was very frustrating and the shuttle was full for the departure, so not usable. If a very large hotel is offering airport Shirley service, it needs to accommodate its guests with more efficiency."
Brandee 5-night trip
Posted 22 hours ago
Embassy Suites Louisville Downtown
The Reserve on Main

The Reserve on Main

10/10 Excellent
"All good."
Jason 2-night trip
Posted 1 day ago
The Reserve on Main
Holiday Inn Louisville Downtown by IHG

Holiday Inn Louisville Downtown by IHG

8/10 Good
"Location is great!"
Karri 5-night trip
Posted 1 day ago
Holiday Inn Louisville Downtown by IHG
Hyatt Regency Louisville

Hyatt Regency Louisville

10/10 Excellent
"Friendly staff, great location, easy parking, breakfast was good, clean"
Lester 3-night trip
Posted 2 days ago
Hyatt Regency Louisville
Moxy Louisville Downtown

Moxy Louisville Downtown

8/10 Good
"No way to get hot water for tea for guests."
David 1-night trip
Posted 7 days ago
Moxy Louisville Downtown

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A historic building with ornate architecture, including columns and decorative moldings.

Louisville Science Center

7.8/10 (6 reviews)
Science is all around us, inescapable. Understand important elements of our world with a visit to this science center for all ages.
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The Kentucky Center for the Performing Arts building facade with large glass windows and a prominent sign.

Kentucky Center for the Performing Arts

8.8/10 (49 reviews)
Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.
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A modern building with a cylindrical structure and a glass facade.

Muhammad Ali Center

8.8/10 (295 reviews)
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A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.
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Golden Statue of David

Find out about the history of Louisville when you take a trip to Golden Statue of David. Attend a sporting event or simply enjoy the lively bars while you're in the area.
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Kentucky Museum of Art and Craft

You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your travels in Louisville. Stroll along the area's riverfront or experience its lively festivals.
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Evan Williams Bourbon Experience

8.6/10 (20 reviews)
You can take time to visit Evan Williams Bourbon Experience during your travels to Louisville. Attend a sporting event or simply enjoy the lively bars while you're in the area.
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SAR Genealogical Research Library: NSSAR Library

You can spend an afternoon browsing the exhibits at SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants.
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Frequently asked questions

What's the area like around 21c Museum Hotel?
21c Museum Hotel is located in a family-friendly area of Louisville known for its beautiful river views and great live music scene. If you're looking for a convenient place to stay, check out the 292 hotels and other accommodations you'll find within a mile.
What's the best place to stay near 21c Museum Hotel?
Adjacent to 21c Museum Hotel, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and 4 restaurants. Other good choices within a short distance include Holiday Inn Express & Suites Louisville Downtown by IHG and Omni Louisville Hotel.
How many hotels will I find close to 21c Museum Hotel?
Expedia has 292 hotels and other accommodations within a mile from 21c Museum Hotel.
If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals near 21c Museum Hotel.
Where can I learn more about changing or cancelling my trip in the area near 21c Museum Hotel?
For additional details about updating your stay near 21c Museum Hotel or cancelling it, click here.
What can I see and do near 21c Museum Hotel?
You might want to spend some time browsing the exhibits at Muhammad Ali Center, Louisville Slugger Museum, or Frazier International History Museum. Explore landmarks like Belle of Louisville, Whiskey Row, and Big Four Bridge. You can watch performances at Louisville Palace, Derby Dinner Playhouse, and Headliners Music Hall if you're interested in local theater.

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