Default HTG hotel image

Find hotels near 21c Museum Hotel, Louisville from ￥17,251

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for 21c Museum Hotel hotels

A wooden staircase with a balustrade leading to a landing.

1. Market Street Inn

Market Street Inn
3.5 star property
2.1 km from 21c Museum Hotel
9.8 out of 10, Exceptional, (127 reviews)
"Such a lovely stay at the Market Street Inn. A very charming, comfortable and feels like home kind of place. Carol and Steve are just the kindest owners. They were responsive and accommodating and always available if needed. We also loved meeting Lisa, who made breakfast each morning and took care of any housekeeping needs. We felt like we were treated as family and not just guests. The area and location is perfect, SUCH a cute little town. Plenty of restaurants, shops and entertainment within...
United States
Ryan
The price is ￥34,863
￥39,396 total
includes taxes & fees
Nov 1 - Nov 2
Market Street Inn
A grand lobby with ornate columns, plush seating, and a chandelier.

2. The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,444 reviews)
"We had a nice stay!"
United States
katisha
The price is ￥16,456
￥19,362 total
includes taxes & fees
Nov 25 - Nov 26
The Brown Hotel
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

3. DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
4.0 star property
Old Louisville, 2.8 km from 21c Museum Hotel
9.6 out of 10, Exceptional, (150 reviews)
"5 STAR B&B"
United States
Casey
The price is ￥22,519
￥26,139 total
includes taxes & fees
Nov 1 - Nov 2
DuPont Mansion Bed & Breakfast
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

4. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (2,208 reviews)
"Beautiful Hotel"
United States
Kristan
The price is ￥32,037
￥37,694 total
includes taxes & fees
Nov 24 - Nov 25
Omni Louisville Hotel
An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

5. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,145 reviews)
"Great stay!"
United States
Addison
The price is ￥16,042
￥18,876 total
includes taxes & fees
Nov 25 - Nov 26
Tempo By Hilton Louisville Downtown Nulu
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.

6. Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (157 reviews)
"Location was great near meant restaurants and nightspots"
United States
Kevin
The price is ￥17,675
￥28,750 total
includes taxes & fees
Nov 10 - Nov 11
Stellar Suites
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

7. The Grady

The Grady
4.0 star property
Downtown Louisville, 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,001 reviews)
"I really enjoyed my stay and hope to return soon."
United States
Donna
The price is ￥22,736
￥26,750 total
includes taxes & fees
Nov 30 - Dec 1
The Grady
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

8. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,001 reviews)
"Staff very friendly"
United States
peter
The price is ￥17,983
￥21,159 total
includes taxes & fees
Nov 23 - Nov 24
Homewood Suites by Hilton Louisville Downtown, KY
A classical gold statue in front of a multi-story building with large windows and a brick facade.

9. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,002 reviews)
"Nice modern rooms and excellent cocktails in the bar."
United States
Erick
The price is ￥23,988
￥29,013 total
includes taxes & fees
Nov 24 - Nov 25
21c Museum Hotel Louisville
A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.

10. Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (860 reviews)
"Hotel was super clean and staff were friendly in a great location"
United States
Sheree
The price is ￥16,397
￥19,292 total
includes taxes & fees
Nov 29 - Nov 30
Moxy Louisville Downtown
An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.

11. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (1,001 reviews)
"Great clean hotel awesome staff."
United States
Anthony
The price is ￥17,898
￥21,059 total
includes taxes & fees
Nov 29 - Nov 30
Aloft by Marriott Louisville Downtown
A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.

12. AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (730 reviews)
"Great stay"
United States
Jen
The price is ￥22,561
￥26,546 total
includes taxes & fees
Nov 8 - Nov 9
AC Hotel Louisville Downtown
A covered patio with a stone wall, a glass table, and a bench.

13. Central Park Bed & Breakfast

Central Park Bed & Breakfast
3.5 star property
Old Louisville, 2.9 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (99 reviews)
"Beautiful 1880’s mansion converted to bed & breakfast. Gorgeous stained glass windows, fireplaces. Innkeeper was super friendly and accommodating/ lives onsite which is very convenient. Hearty and flavorful breakfast. Amazing neighborhood full of beautiful late 1800’s homes. Wish we had more time to explore Olde Louisville"
United States
Nicole
The price is ￥25,309
￥29,377 total
includes taxes & fees
Nov 8 - Nov 9
Central Park Bed & Breakfast
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

14. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (4,430 reviews)
"Great place to stay!!!"
United States
Shun
The price is ￥21,461
￥25,252 total
includes taxes & fees
Nov 8 - Nov 9
Galt House Hotel Trademark Collection by Wyndham
An outdoor dining area with a long table and wicker chairs, overhead lighting, and a view of the city.

15. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (1,097 reviews)
"We’ve stayed here a number of times and we love it. Right in the middle of NuLu, it’s the perfect spot."
United States
Jesse
The price is ￥21,299
￥25,059 total
includes taxes & fees
Nov 18 - Nov 19
Hotel Genevieve part of JdV by Hyatt
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.

16. Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville, 0.7 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,002 reviews)
"Great place"
United States
MILTON
The price is ￥26,440
￥31,111 total
includes taxes & fees
Nov 22 - Nov 23
Louisville Marriott Downtown
A spacious lobby with a central escalator, seating areas, and modern lighting.

17. Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville, 0.6 km from 21c Museum Hotel
8.8 out of 10, Excellent, (1,000 reviews)
"amazing location will definitely be back"
United States
Michael Jered
The price is ￥20,195
￥23,762 total
includes taxes & fees
Nov 23 - Nov 24
Hyatt Regency Louisville
A modern lobby with a central seating area, a reception desk, and a large screen.

18. Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 0.3 km from 21c Museum Hotel
8.8 out of 10, Excellent, (1,839 reviews)
"Great buffet breakfast"
United States
Lisa
The price is ￥14,662
￥17,251 total
includes taxes & fees
Nov 22 - Nov 23
Holiday Inn Express & Suites Louisville Downtown by IHG
A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.

19. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
8.8 out of 10, Excellent, (1,001 reviews)
"Very good hotel, a lot of history on it"
United States
Leonardo
The price is ￥22,482
￥26,452 total
includes taxes & fees
Nov 26 - Nov 27
Seelbach Hilton Louisville Downtown
A modern kitchen with wooden cabinets, a long countertop, and a variety of food items displayed.

20. SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 1 km from 21c Museum Hotel
8.6 out of 10, Excellent, (1,000 reviews)
"Great location. Clean rooms. Nice staff."
United States
Kim
The price is ￥15,947
￥18,764 total
includes taxes & fees
Nov 22 - Nov 23
SpringHill Suites by Marriott Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to 21c Museum Hotel

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A wooden staircase with a balustrade leading to a landing.
Market Street Inn
3.5 star property
9.8
Exceptional
127 reviews
View
A grand lobby with ornate columns, plush seating, and a chandelier.
The Brown Hotel
4.5 star property
9.4
Exceptional
1,444 reviews
View
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.
DuPont Mansion Bed & Breakfast
4.0 star property
9.6
Exceptional
150 reviews
View
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
Omni Louisville Hotel
4.0 star property
9.4
Exceptional
2,208 reviews
View
An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.
Tempo By Hilton Louisville Downtown Nulu
3.5 star property
9.4
Exceptional
1,145 reviews
View

Top 21c Museum Hotel Hotel Reviews

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row

8/10 Good
"The staff was great. The bartender and amenities were very good. The hotel coffee shop was amazing along with the walkable places . Parking however was a nightmare! There was no where to park in their garage, and street parking was hard to find and expensive"
Kateri 4-night trip
Posted 1 hour ago
Cambria Hotel Louisville Downtown-Whiskey Row

Other attractions near 21c Museum Hotel

A historic building with ornate architecture, including columns and decorative moldings.

Louisville Science Center

7.8/10 (6 reviews)
Science is all around us, inescapable. Understand important elements of our world with a visit to this science center for all ages.
See properties

Frequently asked questions

What's the area like around 21c Museum Hotel?
21c Museum Hotel is located in a family-friendly area of Louisville known for its beautiful river views and great live music scene. If you're looking for a convenient place to stay, check out the 292 hotels and other accommodations you'll find within a mile.
What's the best place to stay near 21c Museum Hotel?
Adjacent to 21c Museum Hotel, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and 4 restaurants. Other good choices within a short distance include Holiday Inn Express & Suites Louisville Downtown by IHG and Omni Louisville Hotel.
How many hotels will I find close to 21c Museum Hotel?
Expedia has 292 hotels and other accommodations within a mile from 21c Museum Hotel.
If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals near 21c Museum Hotel.
Where can I learn more about changing or cancelling my trip in the area near 21c Museum Hotel?
For additional details about updating your stay near 21c Museum Hotel or cancelling it, click here.
What can I see and do near 21c Museum Hotel?
You might want to spend some time browsing the exhibits at Muhammad Ali Center, Louisville Slugger Museum, or Frazier International History Museum. Explore landmarks like Belle of Louisville, Whiskey Row, and Big Four Bridge. You can watch performances at Louisville Palace, Derby Dinner Playhouse, and Headliners Music Hall if you're interested in local theater.

Explore a world of travel with Expedia