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Oct 9 - Oct 10
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Oct 10 - Oct 11
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Oct 9 - Oct 11
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Our top choices for 21c Museum Hotel hotels

A grand lobby with ornate columns, plush seating, and a chandelier.
A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.
A grand lobby with ornate ceiling, multiple seating areas, and a staircase.
A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".

1. The Brown Hotel

The Brown Hotel
Downtown Louisville, 1.2 km from 21c Museum Hotel
United States
Meghan
￥19,786
￥23,279 total
includes taxes & fees
Oct 29 - Oct 30
The Brown Hotel
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
A modern living room with a leather sectional sofa, a glass coffee table, and a view of the city skyline through large windows.
An outdoor dining area with tables and chairs, a green building facade, and a row of plants along the wall.
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.

2. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville, 0.8 km from 21c Museum Hotel
United States
Anthony
￥37,378
￥43,979 total
includes taxes & fees
Oct 29 - Oct 30
Hotel Distil, Autograph Collection
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.
A living room with a sofa, a fireplace, a staircase, and a chandelier.
A room with a red velvet sofa, a blue armchair, and a small round table with books.
A room with a large mirror, a wooden dresser, a red patterned rug, and a door with a wreath.

3. DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
Old Louisville, 2.8 km from 21c Museum Hotel
United States
Casey
￥28,763
￥33,386 total
includes taxes & fees
Oct 14 - Oct 15
DuPont Mansion Bed & Breakfast
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
A spacious lobby with a large seating area, a chandelier, and a patterned rug.
A spacious hotel lobby with a central seating area, stone accent walls, and a chandelier.
A modern hotel with multiple floors, large windows, and a prominent sign for Homewood Suites.

4. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
Downtown Louisville, 0.1 km from 21c Museum Hotel
United States
Kelly
￥19,422
￥22,854 total
includes taxes & fees
Oct 25 - Oct 26
Homewood Suites by Hilton Louisville Downtown, KY
A modern bar area with a circular bar, multiple seating options, and a large screen.
A spacious indoor area with a large dining table, multiple chairs, a fireplace, and a kitchen area with a bar.
A modern lobby with a fireplace, seating area, and a reception desk.
A modern living room with a sectional sofa, a small table, and a floor lamp. Large windows offer a view of a cityscape and a building with glass windows.

5. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
Downtown Louisville, 1.2 km from 21c Museum Hotel
United States
William
￥16,502
￥19,416 total
includes taxes & fees
Oct 29 - Oct 30
Cambria Hotel Louisville Downtown-Whiskey Row
An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.
A modern restaurant with high tables and booths, wooden ceiling panels, and framed pictures on the walls.
A modern hotel lobby with a reception desk, seating area, and a large abstract ceiling artwork.
A modern hotel lobby with a brick wall, grey sofas, a coffee table, and a large TV screen displaying "TEMPO by Hilton".

6. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
Phoenix Hill, 2 km from 21c Museum Hotel
United States
Addison
￥19,292
￥22,700 total
includes taxes & fees
Oct 25 - Oct 26
Tempo By Hilton Louisville Downtown Nulu
A covered patio with a stone wall, a glass table, and a bench.
A grand room with a fireplace, a staircase, and a chandelier.
A garden pathway with a lantern, potted plants, and a white fence.
A stone house with a balcony, a front door, and a staircase leading to the entrance.

7. Central Park Bed & Breakfast

Central Park Bed & Breakfast
Old Louisville, 2.9 km from 21c Museum Hotel
United States
Brittany
￥24,000
￥27,856 total
includes taxes & fees
Oct 14 - Oct 15
Central Park Bed & Breakfast
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.
A modern lobby with a central reception desk, seating area, and a large abstract wall art piece.
A modern hotel room with a large bed, a city view, and a unique headboard design.
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.

8. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville, 0.8 km from 21c Museum Hotel
United States
Cameron
￥28,356
￥33,363 total
includes taxes & fees
Oct 18 - Oct 19
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
A building with a sign reading "THE GRADY" at the entrance.
A modern hotel room with a large bed, a desk with a flat-screen TV, a green armchair, and a view of the city through large windows.
A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".

9. The Grady

The Grady
Downtown Louisville, 0.1 km from 21c Museum Hotel
United States
Bruce
￥25,791
￥30,344 total
includes taxes & fees
Oct 25 - Oct 26
The Grady
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.
A modern, well-lit room with a large bed, a green sofa, a small round table, and a kitchen area in the background.
A modern interior with a green wall, black chairs, and a ceiling with exposed beams and lights.
A modern KFC building with large glass windows, a prominent sign, and a well-lit entrance area.

10. Stellar Suites

Stellar Suites
East Market District, 2.2 km from 21c Museum Hotel
￥18,631
￥29,874 total
includes taxes & fees
Oct 18 - Oct 19
Stellar Suites
A classical gold statue in front of a multi-story building with large windows and a brick facade.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.
A steam fountain in a brick alleyway.

11. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville, < 0.1 km from 21c Museum Hotel
United States
Matt
￥25,367
￥30,638 total
includes taxes & fees
Nov 8 - Nov 9
21c Museum Hotel Louisville
An outdoor seating area with wicker furniture and a fire pit.
A modern living room with a sofa, armchairs, a coffee table, and a TV.
An indoor swimming pool with clear water, a diving board, and lounge chairs around the pool area.
A modern lounge area with seating, tables, and a view of the city through large windows.

12. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
Downtown Louisville, 0.3 km from 21c Museum Hotel
￥16,590
￥19,520 total
includes taxes & fees
Nov 5 - Nov 6
Towneplace Suites By Marriott Louisville Downtown
An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.
A modern hotel with a prominent 'Aloft Hotels' sign, multiple floors, and a corner location with a view of the city skyline.
A modern bar area with sofas, tables, and a bar stocked with bottles.
A modern lounge area with a pool table, comfortable seating, a fireplace, and a brick accent wall.

13. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
Downtown Louisville, 0.9 km from 21c Museum Hotel
￥21,399
￥25,178 total
includes taxes & fees
Nov 8 - Nov 9
Aloft by Marriott Louisville Downtown
A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.
A modern hotel room with a large bed, a desk with a chair, a TV mounted on the wall, and a window with a city view.
A cozy living room with a fireplace, a black leather sofa, and a patterned rug.
A modern living room with a sofa, ottomans, a coffee table, and a rug.

14. Moxy Louisville Downtown

Moxy Louisville Downtown
Downtown Louisville, 0.9 km from 21c Museum Hotel
￥20,211
￥23,781 total
includes taxes & fees
Oct 25 - Oct 26
Moxy Louisville Downtown
A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.
A modern restaurant with high ceilings, large windows, and a mix of round and rectangular tables.
A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.
A modern hotel building with a prominent AC Hotel NULU sign, multiple floors, and a well-lit entrance.

15. AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
East Market District, 2 km from 21c Museum Hotel
United States
Jen
￥22,595
￥26,585 total
includes taxes & fees
Oct 25 - Oct 26
AC Hotel Louisville Downtown
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A spacious room with a large dining table, comfortable seating, a sofa, and a view of a bridge.
A balcony with a view of a river, a bridge, and a cityscape.
A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.

16. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville, 0.5 km from 21c Museum Hotel
United States
Saud
￥22,918
￥26,966 total
includes taxes & fees
Oct 25 - Oct 26
Galt House Hotel Trademark Collection by Wyndham
A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.
A bedroom with a bed, a chair, a TV, and a window with curtains.
A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.
A brightly lit grocery store with yellow shelving and a central checkout counter.

17. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
East Market District, 2 km from 21c Museum Hotel
United States
Tyler
￥22,752
￥26,772 total
includes taxes & fees
Oct 26 - Oct 27
Hotel Genevieve part of JdV by Hyatt
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.
A modern bar area with a long counter, multiple chairs, and a bookshelf filled with bottles.
An indoor swimming pool with clear water, surrounded by white marble walls and columns, and furnished with lounge chairs and tables.
A modern hotel room with a living area, a dining area, and a bedroom.

18. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
Downtown Louisville, 0.8 km from 21c Museum Hotel
United States
Frances
￥23,177
￥27,269 total
includes taxes & fees
Oct 30 - Oct 31
Embassy Suites Louisville Downtown
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.
A modern hotel room with a large window offering a city view, a cozy seating area with a sofa and chairs, a dining table with lamps, and a wooden floor.
A modern bar area with glass partitions, bar stools, and a variety of bottles.
A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.

19. Louisville Marriott Downtown

Louisville Marriott Downtown
Downtown Louisville, 0.7 km from 21c Museum Hotel
United States
Veronica
￥35,171
￥41,381 total
includes taxes & fees
Nov 7 - Nov 8
Louisville Marriott Downtown
Lobby sitting area
A hotel room with two beds, a wooden headboard, bedside lamps, a small table, and a patterned rug.
A modern dining area with blue and red seating, wooden tables, and decorative hanging lamps.
A modern interior with a curved wall featuring vertical lines and geometric patterns.

20. Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
Downtown Louisville, 0.3 km from 21c Museum Hotel
United States
Kenneth
￥18,001
￥21,182 total
includes taxes & fees
Oct 29 - Oct 30
Holiday Inn Express & Suites Louisville Downtown by IHG
View all properties

Compare popular hotels close to 21c Museum Hotel

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A grand lobby with ornate columns, plush seating, and a chandelier.
The Brown Hotel
9.4
Exceptional
1,358 reviews
View
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
Hotel Distil, Autograph Collection
9.6
Exceptional
508 reviews
View
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.
DuPont Mansion Bed & Breakfast
9.6
Exceptional
148 reviews
View
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
Homewood Suites by Hilton Louisville Downtown, KY
9.4
Exceptional
1,001 reviews
View
A modern bar area with a circular bar, multiple seating options, and a large screen.
Cambria Hotel Louisville Downtown-Whiskey Row
9.4
Exceptional
1,002 reviews
View

Top 21c Museum Hotel Hotel Reviews

Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown

10/10 Excellent
"Staff was amazing. Really cool hotel"
Michael 1-night trip
Posted less than an hour ago
Aloft by Marriott Louisville Downtown
The Brown Hotel

The Brown Hotel

10/10 Excellent
"Lamps in the room were cracked or broken but holding together"
Kevin 2-night trip
Posted 2 hours ago
The Brown Hotel
The Grady

The Grady

10/10 Excellent
"I really enjoyed my stay and hope to return soon."
Donna 4-night trip
Posted 11 hours ago
The Grady
Hyatt Regency Louisville

Hyatt Regency Louisville

10/10 Excellent
"The hotel it’s very fancy and clean it was good experience"
Hanaa 3-night trip
Posted 15 hours ago
Hyatt Regency Louisville
Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY

10/10 Excellent
"The breakfast was fantastic including many selections, hot and cold. The hotel offers a reception for guests , 5 to 7 PM every Wednesday evening including soup, salad, cheese and crackers, pita bread, cookies, and wine and beer. It was a wonderful treat! The staff all were welcoming and veey helpful."
Dennis 4-night trip
Posted 18 hours ago
Homewood Suites by Hilton Louisville Downtown, KY
Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG

10/10 Excellent
"Clean hotel, located close to main attractions in the city. Comfortable bed, large room. Fairly good WiFi."
Daniel 1-night trip
Posted 20 hours ago
Holiday Inn Express & Suites Louisville Downtown by IHG
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

10/10 Excellent
"It was clean, quite and there is plenty of entertainment close by."
Heather 2-night trip
Posted 3 days ago
Embassy Suites Louisville Downtown
Moxy Louisville Downtown

Moxy Louisville Downtown

10/10 Excellent
"Amazing experience, everyone was helpful and the space was beautiful-- great photo opportunities everywhere and conveniently located. parking was not super far but did need about 5 minutes to walk to and from"
Danielle 2-night trip
Posted 3 days ago
Moxy Louisville Downtown
Louisville Marriott Downtown

Louisville Marriott Downtown

10/10 Excellent
"The room was clean and the hotel was in a great location."
Veronica 3-night trip
Posted 4 days ago
Louisville Marriott Downtown

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A historic building with ornate architecture, including columns and decorative moldings.

Louisville Science Center

7.8/10 (6 reviews)
Science is all around us, inescapable. Understand important elements of our world with a visit to this science center for all ages.
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The Kentucky Center for the Performing Arts building facade with large glass windows and a prominent sign.

Kentucky Center for the Performing Arts

8.8/10 (49 reviews)
Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.
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A modern building with a cylindrical structure and a glass facade.

Muhammad Ali Center

8.8/10 (295 reviews)
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A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.
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Golden Statue of David

Find out about the history of Louisville when you take a trip to Golden Statue of David. Attend a sporting event or simply enjoy the lively bars while you're in the area.
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Kentucky Museum of Art and Craft

You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your travels in Louisville. Stroll along the area's riverfront or experience its lively festivals.
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Evan Williams Bourbon Experience

8.6/10 (20 reviews)
You can take time to visit Evan Williams Bourbon Experience during your travels to Louisville. Attend a sporting event or simply enjoy the lively bars while you're in the area.
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SAR Genealogical Research Library: NSSAR Library

You can spend an afternoon browsing the exhibits at SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants.
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Frequently asked questions

What's the area like around 21c Museum Hotel?
21c Museum Hotel is located in a family-friendly area of Louisville known for its beautiful river views and great live music scene. If you're looking for a convenient place to stay, check out the 292 hotels and other accommodations you'll find within a mile.
What's the best place to stay near 21c Museum Hotel?
Adjacent to 21c Museum Hotel, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and 4 restaurants. Other good choices within a short distance include Holiday Inn Express & Suites Louisville Downtown by IHG and Omni Louisville Hotel.
How many hotels will I find close to 21c Museum Hotel?
Expedia has 292 hotels and other accommodations within a mile from 21c Museum Hotel.
If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals near 21c Museum Hotel.
Where can I learn more about changing or cancelling my trip in the area near 21c Museum Hotel?
For additional details about updating your stay near 21c Museum Hotel or cancelling it, click here.
What can I see and do near 21c Museum Hotel?
You might want to spend some time browsing the exhibits at Muhammad Ali Center, Louisville Slugger Museum, or Frazier International History Museum. Explore landmarks like Belle of Louisville, Whiskey Row, and Big Four Bridge. You can watch performances at Louisville Palace, Derby Dinner Playhouse, and Headliners Music Hall if you're interested in local theater.

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