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Our top choices for Southern Illinois vacation homes

1. Lakeside Shady Rest Home Away from Home blocks from Rend Lake and I57/I64
Lakeside Shady Rest Home Away from Home blocks from Rend Lake and I57/I64Ina
9.8 out of 10, Exceptional, (29 reviews)
The price is ¥16,640
¥33,591 total
includes taxes & fees
Nov 22 - Nov 23

2. Terrific 1-bedroom Loft with Balcony in Mount Vernon. 1.2 mile Hiking trail.
Terrific 1-bedroom Loft with Balcony in Mount Vernon. 1.2 mile Hiking trail.Mount Vernon
10.0 out of 10, Exceptional, (4 reviews)
The price is ¥15,262
¥22,389 total
includes taxes & fees
Nov 9 - Nov 10

3. Brickway Retreat
Brickway RetreatMattoon
9.8 out of 10, Exceptional, (53 reviews)
The price is ¥17,433
¥26,202 total
includes taxes & fees
Nov 9 - Nov 10

4. Vintage Charmer on Main Street
Vintage Charmer on Main StreetGreenup
10.0 out of 10, Exceptional, (79 reviews)
The price is ¥13,978
¥21,029 total
includes taxes & fees
Nov 17 - Nov 18

5. The Vault / Historical 1800s Bank 7min Off I-64. Downtown Main street
The Vault / Historical 1800s Bank 7min Off I-64. Downtown Main streetFairfield
10.0 out of 10, Exceptional, (19 reviews)
The price is ¥14,263
¥17,131 total
includes taxes & fees
Dec 6 - Dec 7

6. The Clark: Where Superheroes Sleep!
The Clark: Where Superheroes Sleep!Metropolis
9.8 out of 10, Exceptional, (19 reviews)
The price is ¥16,260
¥23,447 total
includes taxes & fees
Nov 9 - Nov 10

7. Fish, boat, grill, chill, pets, relax
Fish, boat, grill, chill, pets, relaxSullivan
9.4 out of 10, Exceptional, (72 reviews)
The price is ¥19,018
¥37,288 total
includes taxes & fees
Dec 1 - Dec 2

8. The Tinley House. Close to hiking, hunting. Bike trail and hospital, shopping
The Tinley House. Close to hiking, hunting. Bike trail and hospital, shoppingHarrisburg
10.0 out of 10, Exceptional, (33 reviews)
The price is ¥14,263
¥24,353 total
includes taxes & fees
Nov 9 - Nov 10

9. Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer.
Next door to Wildlife Mgmt Area. Full kitchen, washer/dryer.Kevil
9.8 out of 10, Exceptional, (83 reviews)
The price is ¥18,542
¥21,929 total
includes taxes & fees
Nov 9 - Nov 10

10. Soothing bungalow in charming Joppa
Soothing bungalow in charming JoppaJoppa
The price is ¥15,531
¥32,247 total
includes taxes & fees
Nov 23 - Nov 24

11. Soothing 1-bedroom house in lovely Madison perfect for relaxing stays
Soothing 1-bedroom house in lovely Madison perfect for relaxing staysMadison
The price is ¥12,678
¥15,451 total
includes taxes & fees
Nov 13 - Nov 14

12. In the Country a Beautiful 2-bedroom house with its own private lake
In the Country a Beautiful 2-bedroom house with its own private lakeWaterloo
10.0 out of 10, Exceptional, (42 reviews)
The price is ¥24,961
¥37,876 total
includes taxes & fees
Nov 15 - Nov 16

13. Countryside Private Guest Room
Countryside Private Guest RoomFreeburg
9.8 out of 10, Exceptional, (32 reviews)
The price is ¥11,411
¥14,110 total
includes taxes & fees
Nov 9 - Nov 10

14. Cozy country setting minutes from Rend Lake
Cozy country setting minutes from Rend LakeBenton
10.0 out of 10, Exceptional, (53 reviews)
The price is ¥17,829
¥31,045 total
includes taxes & fees
Nov 19 - Nov 20

15. Charming 1-bedroom house in terrific Harrisburg with AC, WiFi
Charming 1-bedroom house in terrific Harrisburg with AC, WiFiHarrisburg
10.0 out of 10, Exceptional, (22 reviews)
The price is ¥17,908
¥29,561 total
includes taxes & fees
Dec 1 - Dec 2

16. ACE STAYS: Modern 1 BR Townhouse in Mt Carmel
ACE STAYS: Modern 1 BR Townhouse in Mt CarmelMount Carmel
10.0 out of 10, Exceptional, (1 review)
The price is ¥14,263
¥25,529 total
includes taxes & fees
Dec 5 - Dec 6

17. Secluded treehouse with indoor fireplace
Secluded treehouse with indoor fireplaceMakanda
10.0 out of 10, Exceptional, (31 reviews)
The price is ¥19,018
¥29,562 total
includes taxes & fees
Nov 18 - Nov 19

18. Kindlewood ♡ Romantic 2BD Cozy Retreat & Tub with Fireplace, and Outdoor Living
Kindlewood ♡ Romantic 2BD Cozy Retreat & Tub with Fireplace, and Outdoor LivingBluford
10.0 out of 10, Exceptional, (7 reviews)
The price is ¥26,149
¥50,555 total
includes taxes & fees
Nov 15 - Nov 16

19. Explore the Shawnee National Forest-reserve the SHAWNEE HIDEAWAY
Explore the Shawnee National Forest-reserve the SHAWNEE HIDEAWAYEquality
9.6 out of 10, Exceptional, (25 reviews)
The price is ¥20,602
¥33,591 total
includes taxes & fees
Nov 15 - Nov 16

20. Charming 3 bedroom retreat
Charming 3 bedroom retreatHerrin
10.0 out of 10, Exceptional, (4 reviews)
The price is ¥19,810
¥40,981 total
includes taxes & fees
Nov 18 - Nov 19
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Southern Illinois
Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau
































































