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Check availability on Santissima Annunziata Luxury Hotels

Our top choices for Santissima Annunziata luxury hotels

Chapel
Four Seasons Hotel Firenze

Four Seasons Hotel Firenze

Four Seasons Hotel Firenze
5.0 star property
Historic Centre of Florence
9.8 out of 10, Exceptional, (287)
"Five star resort. Staff is incredible "
United States
Scott
The price is ￥170,114
￥190,053 total
includes taxes & fees
Dec 16 - Dec 17
Four Seasons Hotel Firenze
Garden
Hotel Regency

Hotel Regency

Hotel Regency
5.0 star property
Historic Centre of Florence
9.4 out of 10, Exceptional, (441)
"Amazing stay as always. Beautiful hotel but the staff make it great. Feels like a home away from home. Perfect location that is easily walkable everywhere in the historic center."
United States
Aaron
The price is ￥44,898
￥52,315 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Hotel Regency
Lobby lounge
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World
5.0 star property
Historic Centre of Florence
10.0 out of 10, Exceptional, (13)
"This hotel was quite the find! The staff was amazing, attentive, respectful. The amenities, attention to detail, experience was amazing! We will definitely be back."
United States
Nicole
The price is ￥74,830
￥85,240 total
includes taxes & fees
Jan 12 - Jan 13, 2026
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World
Seasonal outdoor pool
The Social Hub Florence Lavagnini

The Social Hub Florence Lavagnini

The Social Hub Florence Lavagnini
4.0 star property
San Lorenzo
9.0 out of 10, Wonderful, (1284)
"Super friendly staff! Great location! "
United States
Jutta
The price is ￥12,099
￥15,870 total
includes taxes & fees
Dec 24 - Dec 25
The Social Hub Florence Lavagnini
Exterior detail
Art Hotel Villa Agape

Art Hotel Villa Agape

Art Hotel Villa Agape
4.0 star property
Oltrarno
9.8 out of 10, Exceptional, (1005)
"A beautiful hotel, extremely clean and with stunning gardens."
United Kingdom
Elizabeth
The price is ￥16,463
￥20,670 total
includes taxes & fees
Dec 16 - Dec 17
Art Hotel Villa Agape
Exterior
Hotel Lungarno - Lungarno Collection

Hotel Lungarno - Lungarno Collection

Hotel Lungarno - Lungarno Collection
5.0 star property
Historic Centre of Florence
9.6 out of 10, Exceptional, (600)
"Excellent location! Truly a 5 star hotel ! Great service, breakfast, and service . Bedrooms were clean! Bathrooms were excellent!"
Canada
Pam
The price is ￥76,926
￥87,545 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Hotel Lungarno - Lungarno Collection
Front of property
Villa Cora

Villa Cora

Villa Cora
5.0 star property
Oltrarno
9.8 out of 10, Exceptional, (468)
"Nice property and staff."
United States
Hugo
Villa Cora
Outdoor spa tub
IQ Hotel Firenze

IQ Hotel Firenze

IQ Hotel Firenze
4.0 star property
Historic Centre of Florence
9.8 out of 10, Exceptional, (1086)
"Beautiful hotel! Great location! Amazing breakfast! Amazing staff! "
Canada
Blair
The price is ￥15,465
￥19,572 total
includes taxes & fees
Dec 24 - Dec 25
IQ Hotel Firenze
Executive Suite (Jacuzzi) | Down comforters, memory foam beds, minibar, in-room safe
Hotel La Scaletta Al Ponte Vecchio

Hotel La Scaletta Al Ponte Vecchio

Hotel La Scaletta Al Ponte Vecchio
4.0 star property
Historic Centre of Florence
8.8 out of 10, Excellent, (952)
"Nice, clean room. Good location and walkable"
United States
Shawn Dee
Hotel La Scaletta Al Ponte Vecchio
Front of property
Hotel Villa Carlotta

Hotel Villa Carlotta

Hotel Villa Carlotta
4.0 star property
Oltrarno
8.2 out of 10, Very Good, (628)
"I enjoyed my stay, everything is amazing. "
Canada
Anna
Hotel Villa Carlotta
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santissima Annunziata Hotel Reviews

Guest House Morandi

Guest House Morandi

10/10 Excellent
"Exquisite Hotel in a perfect location almos! Hidden on a quiet street, yet only 5 min to the Duomo and city center. The rooms are all different and impressive in their own right. If you want a bit of historic art, request the one with the original frescos! Best of all was Dario, who took the time to give us (and write down) all top choices of museum, restaurant, gelato and shopping in the city. He couldn’t have been more kind and helpful. I will 100% stay here again in the future. "
Anna 2-night trip
Posted 3 weeks ago
Guest House Morandi

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Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Santissima Annunziata?
Travel to Florence Airport, Peretola (FLR) Airport and then treat yourself to a stay at one of 5 Santissima Annunziata luxury hotels. During your visit, you might want to enjoy the sightseeing and museums which Santissima Annunziata is known for.
What's the best high-end hotel in Santissima Annunziata?
Four Seasons Hotel Firenze is a luxury hotel with 3 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Hotel Regency and The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World are two other upscale options for your vacation.
How many luxury hotels will I be able to find in Santissima Annunziata?
Lie in the lap of luxury during your getaway to Santissima Annunziata in one of Expedia's 5 luxury hotels.
What's there to see and do in Santissima Annunziata?
Enjoy all that Santissima Annunziata has to offer and visit Statue of David, Gallery of the Academy of Florence, and Piazza Donatello. If you have some spare time during your trip, you might want to check out Palazzo Capponi and Piazza Massimo D'Azeglio.