Santa Cruz Vacation Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Feb 6 - Feb 8
In two months
Mar 20 - Mar 22
In three months
Apr 17 - Apr 19
In four months
May 15 - May 17

Our top choices for Santa Cruz vacation rentals

Living area

Vacation Home in Carolina

Italian modern and private house with amazing panoramic view
2.0 star property
The price is ￥60,508
￥72,337 total
includes taxes & fees
Feb 1 - Feb 2
Italian modern and private house with amazing panoramic view
Pool

Camping in Toa Alta

Bubble room with a view, Jacuzzi spa, kitchen.
The price is ￥31,179
￥47,204 total
includes taxes & fees
Jan 26 - Jan 27
Bubble room with a view, Jacuzzi spa, kitchen.
Fridge, microwave, coffee/tea maker, toaster

Apartment in Sabana Abajo

Segovia Studio Units
3.0 star property
8.6 out of 10, Excellent, (755 reviews)
"An easy safe place to stay before catching my flight."
United States
April
Segovia Studio Units
Terrace/patio

Vacation Home in Naguabo

Casa Parcha
3.5 star property
10.0 out of 10, Exceptional, (34 reviews)
"This retreat was exactly what I was looking for. It offered a quiet stay surrounded by nature. I gave me a chance to reconnect with myself and to enjoy the glorious sounds of the coqui. The communication was top notch. Everyone I encountered was extremely friendly and available to assists with all my needs. This is definitely a gem. "
United States
Ileana
The price is ￥22,858
￥26,831 total
includes taxes & fees
Jan 22 - Jan 23
Casa Parcha
Property grounds

Vacation Home in Ucares

Garden Suite near the Beach and restaurants!
10.0 out of 10, Exceptional, (81 reviews)
"Upscale and awesome accommodation. Beautiful private garden backyard with nice relaxed seating and lounges. Host was very courteous and accommodated our late night check-in."
United States
Leonard
The price is ￥17,085
￥30,224 total
includes taxes & fees
Feb 4 - Feb 5
Garden Suite near the Beach and restaurants!
Aerial view

Apartment in San Juan Antiguo

Ocean Breeze Villa
3.0 star property
10.0 out of 10, Exceptional, (2 reviews)
"no problem with me only thing is accidental pay was last minute and that was a problem for me but it was all a misunderstanding any how when they send me my money back then they can get a 10 out of 10 from me if not then be careful "
United States
Phillip
The price is ￥21,513
￥48,451 total
includes taxes & fees
Jan 27 - Jan 28
Ocean Breeze Villa
Deluxe Villa (Renata) | Beach/ocean view

Villa in Zarzal

Picuas Village
3.0 star property
7.4 out of 10, Good, (59 reviews)
"Tranquil"
United States
Edia
The price is ￥30,549
￥44,552 total
includes taxes & fees
Jan 27 - Jan 28
Picuas Village
Studio, Balcony, Sea View | Free WiFi

Apartment in San Juan Antiguo

Condado Lagoon by Otium
2.5 star property
7.8 out of 10, Good, (13 reviews)
"We loved everything about Condado Lagoon by Otium. Otium’s team was very responsive and quick to answer any questions. The room was spotless, the desk staff were friendly. The area is beautiful and we were able to watch sea turtles off our balcony every day. We didn’t plan to be stuck on the island for 6 extra days, but are very thankful we got to spent the extra time at Condado Lagoon! "
United States
Alexis
The price is ￥22,210
￥42,215 total
includes taxes & fees
Jan 26 - Jan 27
Condado Lagoon by Otium
Pool

Aparthotel in Isla Verde

Mare 1562
4.0 star property
9.2 out of 10, Wonderful, (85 reviews)
"Clean, great view and direct beach access. "
United States
Kristin
Mare 1562
Basic Apartment | 2 bedrooms, free WiFi, bed sheets

Apartment in Universidad

Villas at Auxilio Mutuo 104
3.0 star property
8.2 out of 10, Very Good, (14 reviews)
"Great space to stay, every necessary amenity available, enjoyed my time in San Juan!"
United States
Denzel
The price is ￥25,468
￥32,071 total
includes taxes & fees
Jan 26 - Jan 27
Villas at Auxilio Mutuo 104
Terrace/patio

Apartment in Naguabo

El Yunque Rainforest
3.5 star property
10.0 out of 10, Exceptional, (46 reviews)
"Everything was amazing"
United States
Heidi
The price is ￥40,180
￥48,227 total
includes taxes & fees
Jan 26 - Jan 27
El Yunque Rainforest
Luxury Villa | Private pool

Villa in Pitahaya

SELVA by DW
4.0 star property
10.0 out of 10, Exceptional, (2 reviews)
"This was our 1st experience in PR. This house was AMAZINGLY beautiful and really show cased the outdoor space!! It was VERY clean, high quality linens. Had a nice cook space. The space it self was STUNNING!! The outdoor space was PERFECTION!!!! We actually booked for the lounge net area, and it did not disappoint!! **Downfalls [we understand that somethings are out of anyones control so more of a FYI] -There was nothing "comfy" about the house. It is all cement: bed frame, entire bathroom so...
United States
Jamie leigh
SELVA by DW
Smart TV

Vacation Home in Ciénaga Baja

Casa Dulce
2.0 star property
8.6 out of 10, Excellent, (4 reviews)
"We were pleased with our stay. Great value for the space. Easy access to El Yunque. Host provided coffee, but no other food or spices. Beds were comfortable. We would stay here again. "
United States
Bruce H.
The price is ￥11,254
￥25,361 total
includes taxes & fees
Jan 22 - Jan 23
Casa Dulce
Deluxe Studio Suite, 1 Queen Bed, Garden View | Bathroom | Eco-friendly toiletries, hair dryer, towels, soap

Aparthotel in Santurce

DUNA by DW
4.5 star property
9.6 out of 10, Exceptional, (65 reviews)
"Great stay. "
United States
Albany
DUNA by DW
Exclusive Studio (MM1) | Living room | Smart TV

Villa in Santurce

MANSION MIRAFLORES
3.0 star property
9.4 out of 10, Exceptional, (155 reviews)
"The room was perfect, we loved the kitchenette. The access with the scooters were amazing."
United States
Anthony
MANSION MIRAFLORES
Property amenity

Aparthotel in Isla Verde

Casa Costera, Isla Verde Beach, Apartments by Marriott Bonvoy
2.5 star property
9.0 out of 10, Wonderful, (153 reviews)
"Good accommodation "
United States
Megan
The price is ￥48,272
￥57,362 total
includes taxes & fees
Feb 18 - Feb 19
Casa Costera, Isla Verde Beach, Apartments by Marriott Bonvoy
Junior Quadruple Room, City View | Living area | Smart TV

Aparthotel in San Juan Antiguo

Romeo Gay Hotel
4.0 star property
9.0 out of 10, Wonderful, (157 reviews)
"Parking was good, hotel and room was clean, front desk was really nice and the location was good."
United States
axel
Romeo Gay Hotel
Presidential Apartment, City View | Living area

Aparthotel in Old San Juan

Hugo's Rental
5.0 star property
9.4 out of 10, Exceptional, (282 reviews)
"Convenient spot to stay while exploring Old San Juan"
United States
Weston
The price is ￥28,074
￥32,565 total
includes taxes & fees
Jan 25 - Jan 26
Hugo's Rental
Outdoor pool

Aparthotel in Isla Verde

Mare 1660
4.0 star property
8.6 out of 10, Excellent, (84 reviews)
"It was a good stay but pool photo in add is misleading."
United States
Nataliya
Mare 1660
Outdoor pool

Apartment in Humacao

Palmas View Premium 7
9.6 out of 10, Exceptional, (11 reviews)
"Absolutely no issues and everything was great!"
United States
Beau D.
The price is ￥25,627
￥43,485 total
includes taxes & fees
Jan 22 - Jan 23
Palmas View Premium 7
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Cruz Hotel Reviews

San Juan Airport Hotel

San Juan Airport Hotel

10/10 Excellent
"Good enough for a night. No microwave or mini fridge was provided "
alexander 1-night trip
Posted 1 day ago
San Juan Airport Hotel

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz
  • Use the map to find apartments and other holiday homes in the Santa Cruz neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Cruz while they last

Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, we have vacation rentals near well known points of interest in Santa Cruz, or you can go with a more remote option if you want a relaxing place to stay.

What are some of the best vacation home rentals that Santa Cruz has to offer?

150 Sol by Stay with Bear: This vacation home rental near Santa Cruz is in the historical district and equipped with air-conditioning and Netflix to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a full-sized fridge, a stovetop, and a microwave.

What can I see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Carabali Rainforest Park, or get outside and enjoy nature at Luquillo Beach. Other popular places to visit in the area include Port of San Juan and El Yunque National Forest.

What are vacation rentals like in Santa Cruz?

Vacation rentals are privately owned accommodations you can stay in for a few days or a quick weekend in Santa Cruz. Vacation rentals feature amenities such as laundry facilities and kitchens so you'll have all the comforts of home. If you're concerned about a sanitized environment, vacation rentals can provide a sense of seclusion away from shared hotel elevators and bustling concierge desks while still allowing you to travel. You'll also have more space in a vacation rental than in a traditional hotel, which makes a vacation rental an attractive option for a family trip or a small group gathering.