Book a Santa Cruz Resort

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks
In one month
In two months

Resorts in Santa Cruz

No exact matches found, but these alternatives could be just right

Recommended hotels in Santa Cruz

Sun Hotel

3.5 star property
Santa Cruz
8.4 out of 10, Very Good, (329)
"Staff spoke English. Airport pickup beat any US hotel. Rooms nice. Restaurant was ok"
United States
Peter
The price is ¥13,963
¥13,963 total
Dec 5 - Dec 6
Sun Hotel

Marriott Santa Cruz de la Sierra Hotel

5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (210)
"Great hotel, food and location albeit a little expensive "
United States
Reinaldo
The price is ¥17,322
¥17,322 total
Dec 12 - Dec 13
Marriott Santa Cruz de la Sierra Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (345)
"Accommodating staff, comfortable rooms, wonderful pool"
Canada
Jay
The price is ¥19,729
¥19,729 total
Dec 7 - Dec 8
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Camino Real Hotel

4.5 star property
Santa Cruz
8.8 out of 10, Excellent, (407)
"The parrots. Unique"
United States
Juan P
The price is ¥19,627
¥19,627 total
Dec 25 - Dec 26
Camino Real Hotel

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (253)
"Nice hotel "
United States
Narciso Lorenzo
The price is ¥9,970
¥9,970 total
Jan 1 - Jan 2, 2026
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Novotel Santa Cruz De La Sierra

5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (103)
"Great location and very clean hotel. Will stay again soon."
United States
William
The price is ¥15,577
¥15,577 total
Dec 18 - Dec 19
Novotel Santa Cruz De La Sierra

Cosmopolitano Hotel Boutique

3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (122)
"Great place: great staff"
United States
Linda
Cosmopolitano Hotel Boutique

Chairú Eco Hotel

3.5 star property
Santa Cruz
9.6 out of 10, Exceptional, (45)
"Nice property. Would definitely stay there again and again. Only negative was on our last night there was a really noisy party next door that lasted until 2am. "
United States
Andrew
Chairú Eco Hotel

HOTEL OSHO

3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (33)
"Excellent"
United States
Neysa
HOTEL OSHO

Prince Hotel

3.0 star property
Santa Cruz
The price is ¥8,412
¥8,724 total
Dec 5 - Dec 6
Prince Hotel

Ibis Santa Cruz DE LA Sierra

3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (72)
"Great Spot"
United States
Jose
The price is ¥5,944
¥5,944 total
Dec 18 - Dec 19
Ibis Santa Cruz DE LA Sierra

Premium Suites Deluxe Aparthotel Equipetrol

3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (80)
"Good price, great hotel!"
United States
James
The price is ¥6,048
¥6,048 total
Dec 16 - Dec 17
Premium Suites Deluxe Aparthotel Equipetrol

Hotel Cortez

3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (121)
"The staff and property are second to none! "
United States
Cynthia
The price is ¥14,435
¥14,435 total
Dec 13 - Dec 14
Hotel Cortez

Posada Express Fast Check

3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (2)
The price is ¥7,789
¥8,568 total
Jan 1 - Jan 2, 2026
Posada Express Fast Check

Urban Suites

3.0 star property
Santa Cruz
The price is ¥8,354
¥8,354 total
Dec 6 - Dec 7
Urban Suites

Casa Por Temporadas

2.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1)
"The front desk staff was amazing! We checked in during a rain storm and the hotel had been hit by lightning and their computers and they computers were out. The staff maintained their professionalism and got us in a room quickly. Thank you for your help "
United States
Cynthia
The price is ¥13,260
¥13,260 total
Dec 16 - Dec 17
Casa Por Temporadas

Swissôtel Santa Cruz De La Sierra

4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (81)
"Beautiful hotel"
Australia
Joanna
The price is ¥14,120
¥14,120 total
Jan 1 - Jan 2, 2026
Swissôtel Santa Cruz De La Sierra

Lido Hotel

3.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (30)
"Very helpful and nice staff. Quiet location. near the central plaza. Great value "
United Kingdom
David
The price is ¥7,135
¥7,135 total
Dec 5 - Dec 6
Lido Hotel

TRYP by Wyndham Santa Cruz

4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (144)
"Nice stay with good service "
United States
Jianyuan
The price is ¥11,833
¥11,833 total
Dec 16 - Dec 17
TRYP by Wyndham Santa Cruz

Equipetrol Suites Apart Hotel

2.5 star property
Santa Cruz
8.4 out of 10, Very Good, (7)
"Perfect hotel"
Turkey
Yener
Equipetrol Suites Apart Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

Santa Cruz Resorts information

Number of reviews
2,374
Accommodation
1 Resorts
Lowest Price
¥5,944
Highest Price
¥19,729

Frequently asked questions

What can I expect from a resort vacation in Santa Cruz?
Longing for a relaxing getaway? Treat yourself to the luxuries and comforts of a resort, where you can find everything you need for your stay from tasty food and drink options to activities and shopping. Browse the resort options in the area and discover the one that's best for you, whether you see yourself kicking back in a luxury suite or checking out the on-site boutiques.
What's a favorite resort for my stay in Santa Cruz?
Our top-rated resort near Santa Cruz: Terramia Resort - Family-friendly resort. 23.1 mi (37.2 km) from Santa Cruz. Features a children's pool, a garden, and free self parking.
What can I do in Santa Cruz?
Check out the interesting exhibits at Ethno-folkloric Museum and Sacred Art Museum, or catch the latest production at Cine Center or Casa Municipal de Cultura Raúl Otero Reiche. A few other attractions you may want to see are Plaza 24 de Septiembre and Blacutt Square.
What's the weather like in Santa Cruz?
The hottest months are usually October and November with an average temp of 79°F, while the coldest months are June and July with an average of 70°F. Average annual precipitation for Santa Cruz is 48 inches.
What's the best way to get to and around Santa Cruz?
Fly into Santa Cruz (VVI-Viru Viru Intl.), which is located 9.8 mi (15.8 km) from the city center. If you want to venture outside of the area, ride aboard one of the trains from Santa Cruz de la Sierra Station.

Explore a world of travel with Expedia