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Find hotels in Uptown, San Antonio

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Our top choices for Uptown hotels

Comfort Suites San Antonio North - Stone Oak

Comfort Suites San Antonio North - Stone Oak
2.5 star property
Uptown
8.6 out of 10, Excellent, (1000)
"Excellent stay, great place highly recommended "
United States
Cesar
The price is ¥11,799
¥13,776 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Comfort Suites San Antonio North - Stone Oak

Home2 Suites by Hilton San Antonio North-Stone Oak, TX

Home2 Suites by Hilton San Antonio North-Stone Oak, TX
3.0 star property
Uptown
8.8 out of 10, Excellent, (885)
"Clean room amicable staff great amenities "
United States
KAREN
The price is ¥13,852
¥16,374 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Home2 Suites by Hilton San Antonio North-Stone Oak, TX

Estancia del Norte San Antonio, Tapestry Collection by Hilton

Estancia del Norte San Antonio, Tapestry Collection by Hilton
3.5 star property
Uptown
8.8 out of 10, Excellent, (1001)
"Convenient location and quiet ambiance to relax after a long day of exploring around the city. "
United States
Meghan
The price is ¥21,079
¥24,917 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Estancia del Norte San Antonio, Tapestry Collection by Hilton

Spark by Hilton San Antonio Airport

Spark by Hilton San Antonio Airport
2.0 star property
Uptown
8.6 out of 10, Excellent, (1066)
"The room was perfect and the staff were super helpful."
United States
Sonoma
The price is ¥10,771
¥13,017 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Spark by Hilton San Antonio Airport

Embassy Suites by Hilton San Antonio Airport

Embassy Suites by Hilton San Antonio Airport
3.5 star property
Uptown
8.8 out of 10, Excellent, (1076)
"Great hotel for large families!"
United States
Jennifer
The price is ¥21,380
¥25,273 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Embassy Suites by Hilton San Antonio Airport

Drury Plaza Hotel San Antonio Airport

Drury Plaza Hotel San Antonio Airport
3.0 star property
Uptown
9.4 out of 10, Exceptional, (1948)
"Always happy to stay at the Drury Inn. Rooms are clean and staff are friendly. "
United States
Rocio
The price is ¥14,036
¥16,591 total
includes taxes & fees
Jan 29 - Jan 30, 2026
Drury Plaza Hotel San Antonio Airport

Days Inn by Wyndham San Antonio Airport

Days Inn by Wyndham San Antonio Airport
2.0 star property
Uptown
8.0 out of 10, Very Good, (1002)
"The check-in was fast and efficient. The person who checked us in was courteous and professional. "
United States
Wynonie
The price is ¥8,171
¥9,538 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Days Inn by Wyndham San Antonio Airport

WoodSpring Suites San Antonio Stone Oak

WoodSpring Suites San Antonio Stone Oak
2.5 star property
Uptown
8.2 out of 10, Very Good, (688)
"Staff was nice and friendly! The location had very easy access to the freeway. "
United States
Lidiana
The price is ¥10,789
¥12,753 total
includes taxes & fees
Jan 1 - Jan 2, 2026
WoodSpring Suites San Antonio Stone Oak

Courtyard by Marriott San Antonio Airport

Courtyard by Marriott San Antonio Airport
3.0 star property
Uptown
8.4 out of 10, Very Good, (1002)
"Good hotel, great staff. "
United States
Brett
The price is ¥13,918
¥16,452 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Courtyard by Marriott San Antonio Airport

Super 8 by Wyndham San Antonio/I-35 North

Super 8 by Wyndham San Antonio/I-35 North
2.0 star property
Uptown
6.8 out of 10, (1000)
"Clean room"
United States
Esmeralda
The price is ¥7,975
¥9,311 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Super 8 by Wyndham San Antonio/I-35 North

Courtyard by Marriott San Antonio Airport/North Star Mall

Courtyard by Marriott San Antonio Airport/North Star Mall
3.0 star property
Uptown
8.2 out of 10, Very Good, (788)
"good place to stay"
United States
nadine
The price is ¥12,385
¥14,460 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Courtyard by Marriott San Antonio Airport/North Star Mall

Hilton Garden Inn San Antonio Airport South

Hilton Garden Inn San Antonio Airport South
3.0 star property
Uptown
8.4 out of 10, Very Good, (1000)
"Friendly Staff and Clean Room"
United States
Patrick
The price is ¥13,091
¥15,770 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Hilton Garden Inn San Antonio Airport South

Hilton Garden Inn San Antonio Airport

Hilton Garden Inn San Antonio Airport
3.0 star property
Uptown
8.0 out of 10, Very Good, (1000)
"Room was clean and staff was courteous. "
United States
son
The price is ¥12,695
¥15,007 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hilton Garden Inn San Antonio Airport

Americas Best Value Inn San Antonio Airport South

Americas Best Value Inn San Antonio Airport South
2.0 star property
Uptown
7.8 out of 10, Good, (310)
"Friendly staff "
United States
William
The price is ¥8,578
¥10,014 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Americas Best Value Inn San Antonio Airport South

Best Western Garden Inn

Best Western Garden Inn
2.5 star property
Uptown
8.2 out of 10, Very Good, (1003)
"Clean room, friendly and helpful staff."
United States
Robyn
The price is ¥10,604
¥12,380 total
includes taxes & fees
Jan 22 - Jan 23, 2026
Best Western Garden Inn

Hampton Inn San Antonio Stone Oak

Hampton Inn San Antonio Stone Oak
2.5 star property
Uptown
8.4 out of 10, Very Good, (772)
"Food - eggs were swimming in water, sausage patty was unevenly overcooked and inedible. Potatoes not far behind. Good coffee. Nick was professional & attentive behind the desk. "
United States
Patrick
The price is ¥12,662
¥14,783 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Hampton Inn San Antonio Stone Oak

SureStay Plus Hotel by Best Western San Antonio North

SureStay Plus Hotel by Best Western San Antonio North
2.5 star property
Uptown
7.0 out of 10, Good, (1001)
"Clean room but musty smell. Staff is super friendly and helpful."
United States
Robyn
The price is ¥7,820
¥9,129 total
includes taxes & fees
Jan 4 - Jan 5, 2026
SureStay Plus Hotel by Best Western San Antonio North

Marriott San Antonio Airport

Marriott San Antonio Airport
4.0 star property
Uptown
8.6 out of 10, Excellent, (1000)
"Great hotel"
United States
Kassie
The price is ¥17,313
¥20,465 total
includes taxes & fees
Jan 23 - Jan 24, 2026
Marriott San Antonio Airport

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
2.5 star property
Uptown
9.4 out of 10, Exceptional, (1527)
"It was a great stay. "
United States
Juan Carlos
The price is ¥12,361
¥14,612 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Home2 Suites by Hilton San Antonio Airport, TX

Home2 Suites by Hilton San Antonio Airport, TX
3.0 star property
Uptown
8.6 out of 10, Excellent, (1003)
"Very good stay "
United States
Roberto
The price is ¥13,916
¥16,449 total
includes taxes & fees
Jan 29 - Jan 30, 2026
Home2 Suites by Hilton San Antonio Airport, TX
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Uptown

Find the best Uptown areas and neighborhoods for the activities you enjoy most.

Downtown San Antonio

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Stone Oak

Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista while you're in town.

Medical Center District

While visiting Medical Center District, you might make a stop by sights like USAA Corporate Office Headquarters and The San Antonio Art Institute.

Near East Side

If you're spending some time in Near East Side, Alamodome and Carver Community Cultural Center are top sights worth seeing.

Top Uptown Hotel Reviews

Frequently asked questions

What's it like in Uptown?
Guests are sure to enjoy their time checking out all that San Antonio's Uptown neighborhood has to offer. Looking for sights you might find in a travel guide about Uptown? Consider a visit to San Antonio River while you're in the neighborhood.
What's the best accommodation in Uptown?
Based on Expedia customer reviews, Heritage Inn & Suites San Antonio Airport, Trademark Wyndham is the highest ranked property in Uptown. This hotel is a short 14-minute walk from North Star Mall, and it offers free breakfast and an outdoor pool. Other favorite options in the area include Wyndham Garden San Antonio Airport and Drury Plaza Hotel San Antonio Airport.
How many hotels will I be able to find in the Uptown area?
Expedia has 373 hotels and other accommodations in Uptown to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Uptown, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the top deals on offer in Uptown.
Where can I learn more about changing or cancelling my trip to Uptown?
To find more details about picking new dates or cancelling your trip to Uptown, click here.
What can I see and do in this San Antonio neighborhood?
Uptown's sights and attractions like Toilet Seat Museum, Marion Koogler McNay Art Museum, and Parchman Stremmel Galleries offer insight into the local culture. You could also plan a visit to San Antonio River or Alamo Quarry Market while you're in the neighborhood. A few places to visit in the area around Uptown include Harry B Orem Stadium, Quarry Golf Club, and Regal Alamo Quarry. McDermott Center and UIW Tennis Center are also worth a visit when you're out sightseeing in San Antonio.

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