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Find hotels in Panacea, FL from ¥11,202

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Compare 491 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

The Panacea Motel

2.0 star property
9.0 out of 10, Wonderful, (104)
"We absolutely loved this quaint little motel. It was very clean and quiet. The staff was very friendly and accommodating. We will definitely be returning."
The Panacea Motel

The Lodge at Wakulla Springs

3.0 star property
9.2 out of 10, Wonderful, (953)
"Beautiful area "
The Lodge at Wakulla Springs

Wildwood Inn

3.0 star property
8.6 out of 10, Excellent, (1004)
"An enjoyable stay. Thank you."
The price is ¥16,695
¥19,202 total
includes taxes & fees
Aug 11 - Aug 12
Wildwood Inn

Best Western Wakulla Inn & Suites

2.5 star property
8.8 out of 10, Excellent, (912)
"We absolutely love this venue and stay here when we visit our family every year! "
The price is ¥17,132
¥19,102 total
includes taxes & fees
Aug 10 - Aug 11
Best Western Wakulla Inn & Suites

St James Bay Golf & Pickleball Resort

3.5 star property
9.0 out of 10, Wonderful, (344)
"The resort was very pretty. Grounds are well kept. Facilities are in nice condition. Pretty cool that you have your own washer/dryer in the villas. If you want a beach, there isn't too much close by. Carrabelle beach is about 20 minutes away, nice, but small, and no shops or restaurants near. St. George Island is about 30 minutes. Worth the drive. Good beach, lots of shops, lighthouse & museum, etc."
The price is ¥23,384
¥25,839 total
includes taxes & fees
Aug 3 - Aug 4
St James Bay Golf & Pickleball Resort

The Moorings Hotel and Marina

2.5 star property
8.4 out of 10, Very Good, (33)
"Loved the view of the marina from our room"
The price is ¥26,544
¥29,331 total
includes taxes & fees
Aug 5 - Aug 6
The Moorings Hotel and Marina

Franklin Inn

2.0 star property
7.8 out of 10, Good, (420)
"The Franklin Inn is a frequent go to. The staff is always welcoming and helpful. This is a convenient, clean, maintained, and reasonable stay."
The price is ¥11,202
¥12,379 total
includes taxes & fees
Aug 3 - Aug 4
Franklin Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Panacea

Experience relaxing Panacea: its beaches, fishing, sunsets, and more!

Top Panacea Hotel Reviews

Frequently asked questions

Where is the best place to stay in Panacea?

Expedia customers give high marks to The Panacea Motel. See all available top hotels, or vacation rentals in Panacea.

What's the top vacation rental in Panacea?

Secluded Florida Beach Bungalow SPECIAL!!! 10% OFF JULY: Visitors give good reviews to this Panacea vacation home rental, which is located near the beach and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. You and your friends and family can relax into your vacation with amenities like a selection of books. Other favorite homes for rent in Panacea are Tiki House is a Unique Beach Front gathering spot for family, friends and PUPs. and Coastal Getaway on canal-steps to the beach. See all vacation rentals in Panacea.

If I need to cancel my hotel reservation in Panacea, will I receive a refund?

Yes! Most hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Panacea.

Where can I learn more about changing or cancelling my trip to Panacea?

For more details about changing or cancelling your trip to Panacea, click here.

What's the best pet-friendly place to stay in Panacea?

The Panacea Motel is a top pet-friendly option for your stay. See more pet-friendly hotel accommodations in Panacea.

Where is the best hotel to stay with easy access to USS Mohawk CGC Veterans Memorial Reef?

Best Western Wakulla Inn & Suites is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. You'll find it 5.7 mi (9.1 km) from USS Mohawk CGC Veterans Memorial Reef. Another good option is Magnuson Hotel Wildwood Inn, located 6.5 mi (10.5 km) away.

What are some accommodations with pools in Panacea?

7 Bedroom Beach House with POOL!! Gulf Front and Bay Front: Offers complimentary wireless internet access, a pool, and kitchens. View all hotels with pools in Panacea.

What is the best spa hotel in Panacea?
What's the best hotel for staying near Tallahassee Regional Airport (TLH)?

Tallahassee Sun & Moon is one of the top choices for your stay and is a popular property, featuring free WiFi and free parking. It's located 3.5 mi (5.7 km) from Tallahassee Regional Airport. Other options close to the airport include Hampton Inn & Suites Tallahassee Capitol-University and Governors Inn.

What's it like to stay in Panacea?

Nature enthusiasts will enjoy exploring Panacea, and many visitors are sure to appreciate the beaches and seafood restaurants. The relaxing and tucked away setting also entices those visiting the city. In Panacea, there are 201 hotels and other accommodations to choose from. Find out more about Panacea.

What are the top places to visit in Panacea?

Natural beauty is on display at Mashes Sand Beach, Wilson Beach, and Alligator Point Beach. Dolphin watching is a great activity, and Bayside Marina is one place to visit. A couple of additional sights to add to your agenda are Bald Point State Park and Public Beach Access. Check out what more to see and do in Expedia's Panacea guide.

What's the seasonal weather like in Panacea?

The hottest months are usually July and August with an average temp of 81°F, while the coldest months are January and February with an average of 58°F. The rainiest months in Panacea are August, July, June, and September, with each month seeing an average of 8 inches of rainfall.