Panacea Vacation Rentals from ￥49,052: Search Short-Term Rentals

Check prices for these dates

In two weeks

In two months

In three months

In four months

Our top choices for Panacea vacation rentals

A tree silhouetted against a sunset sky, a body of water, and a snowy landscape.

1. Cozy Panacea Retreat #3 (King)

Panacea

Faith V.

￥28,079 total

includes taxes & fees

Oct 4 - Oct 5

A modern kitchen with a wooden countertop, a built-in sink, and a dining area with a table and chairs.

2. Panacea Treehouse- Quiet- Waterfront Pet Friendly Fall Fishing Retreat

Panacea

Benjamin S.

￥49,052 total

includes taxes & fees

Oct 5 - Oct 6

A cozy living room with a brown leather sofa, a dining table set with plates, and a view of the sea through large windows.

3. romantic get away for 2 right on the Ochlockonee river

Panacea

Laurie K.

￥49,140 total

includes taxes & fees

Oct 4 - Oct 5

A covered outdoor area with a wooden deck, white furniture, and a view of the water.

4. Tiny Tides Waterfront Cottage

Panacea

Jason W.

￥65,749 total

includes taxes & fees

Oct 7 - Oct 8

A dock extending into a body of water with a covered structure at the end.

5. Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks

Panacea

Toby H.

￥75,875 total

includes taxes & fees

Oct 4 - Oct 5

A porch with wicker chairs and a small table, overlooking a lake and trees.

6. Point & Paddle Waterfront Retreat @Alligator Point

Alligator Point

Scott A.

￥76,708 total

includes taxes & fees

Oct 25 - Oct 26

A wooden bench in a natural setting with a lake and trees in the background.

7. 09) Queen Kitchenette by the Bay

Panacea

￥28,079 total

includes taxes & fees

Oct 4 - Oct 5

8. Queen Kitchenette by the Bay #11

Panacea

￥28,237 total

includes taxes & fees

Oct 4 - Oct 5

View all properties

Find vacation rentals that suit your style

Apartments

Cottages

Save an average of 15% on thousands of hotels when you're signed in

Sign in

Sign up, it's free

Top Panacea Hotel Reviews

Great sunrise view from dining area and decks. Easy beach access.

10/10 Excellent

"Property is clean and in a great location for peace and quiet. We enjoyed meeting the host and I'm sure will book with them again."

Hideaway Beach Cottage on waterfront with amazing views.

10/10 Excellent

"Booking this stay was incredibly easy. Hosts are responsive and very accommodating. Price was great, especially considering that we thought the property was even better in person. Pictures truly don’t do it justice. The small town of Panacea is a breath of fresh air. Not your typical touristy beach town. We wanted to have a slow, low stim vacation with our young kids and that’s exactly what we got. There are still enough restaurants to choose from if you want to eat out every night in the town and even more within a 20 minute drive. If you want to stay in and cook, the kitchen has plenty of room and is stocked well. Large dining table with more than enough room. The living area large and comfy. We didn’t use the second bedroom beds because our kids are still in pack and plays. Two fit in the room just fine. The master bedroom mattress was genuinely one of the most comfortable beds I’ve slept in. Screened in porch was amazing to relax in and let in 0 bugs somehow. So impressed. Our absolute favorite part though was the yard and little beach on the bay. Our kids can’t stand to be inside and they played for HOURS in the good sized yard. We watched stingrays, fish, and birds in the bay. The only thing I’d tell people to consider is that the beach can be a drive. The closest beach, Mashes Sands, had almost no shoreline so you’ll need to drive \- 20 minutes for a beach. This didn’t bother us at all. There is virtually no traffic and tons of options."

Happy Shack BEACH & BAY! Kayak, paddle boards, tiki hut, firepit, grille, wifi

10/10 Excellent

"This was our first stay at the Happy Shack but it will not be our last. It's name says it all. It is such a fun, whimsical, eclectic, happy place to be if you want a great vacation and a break from reality and the everyday hustle and bustle of life. We where there over Labor Day Weekend and through the week. We maybe saw 3 or 4 families near the private beach access over the Holiday weekend and there was literally no one else there during the week but us. It was like having our own private beach all to ourselves. It is a very easy and quick walk across the street. My husband and boys enjoyed fishing off the beach and one of them even caught a stingray. I saw multiple dolphins feeding on mullet just feet from the shore before sunset one evening. And the first walk on the beach I found my first whole sand dollar in it's natural setting, I had never found one of those before just walking the beach. Just Amazing is all I can say about the Happy Shack!!"

Coastal Getaway on canal-steps to the beach

10/10 Excellent

"Awesome weekend staying at this location. We was within walking distance to the beach and fishing. Loved that it had a complete bathroom downstairs when we came in from fishing all day and night. Great communication with the host. Very prompt responding to questions. Will recommend to family and friends!!"

"Somewhere In The Sun" Beachfront Cottage - Old Florida Style Hideaway

10/10 Excellent

"Great beach bungalow. Pictures don’t do it justice. Much more spacious than we anticipated. Had everything we needed. Very cute and wonderful views of the beach. Area was great for us, quiet, private, not touristy at all. We saw so many stars at night, even saw the Milky Way the first night there. Definitely recommend if you are looking for that old school small Florida beach house vibe."

Find out more about Panacea

Search for holiday rentals in Panacea on Expedia! You can easily find your home rentals, villas, holiday apartments in Panacea using one of the methods below:

View our selection of featured holiday rentals in Panacea
Use the map to find apartments and other holiday homes in the Panacea neighbourhood you prefer
Enter your travel dates to view the best deals on holiday rentals in Panacea while they last

Look no further and take a look at our great range of rental properties in Panacea!

Frequently asked questions

Can I find vacation rentals in Panacea?

Yes, there are vacation rentals in Panacea close to Gulf Specimen Public Aquarum, or you can go with a secluded option if you'd like a relaxing place to stay. Visitors to Panacea speak positively about the beaches and seafood restaurants in this destination.

What are some of the best vacation rentals in Panacea?

BEACH FRONT to BAY with boatdock, swimming pool, pickleball courts and kayaks.: Visitors give good reviews to this Panacea vacation home rental, which is located on the beach and has an outdoor pool, a balcony, and air-conditioning to put you at ease in your new surroundings. It has 6 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You can relax into your vacation with a garden and a selection of games. Some other homes for rent in Panacea include Your Fall Escape: FSU Football & Scalloping and Coastal Getaway on canal-steps to the beach.

How many vacation rentals are there in Panacea?

Choose from 177 Expedia vacation rentals in Panacea for a memorable vacation.

What’s there to see and do in Panacea?

Mashes Sand Beach and Alligator Point Beach are a couple of lovely local spots to enjoy the outdoors, whereas family-friendly attractions include Gulf Specimen Public Aquarum. While here, Bald Point State Park and Wilson Beach are other places worth a visit.

What’s a vacation rental in Panacea like?

Vacation rentals are privately owned properties where you can stay for a few weeks or just a few days in Panacea. Vacation rentals offer amenities like laundry facilities and kitchens so you'll have everything you need. If you're concerned about cleanliness, vacation rentals can offer a sense of seclusion away from shared hotel elevators and busy reception areas while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental a popular choice for family trips or small group gatherings.

Room 1

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Panacea vacation rentals

1. Cozy Panacea Retreat #3 (King)

2. Panacea Treehouse- Quiet- Waterfront Pet Friendly Fall Fishing Retreat

3. romantic get away for 2 right on the Ochlockonee river

4. Tiny Tides Waterfront Cottage

5. Waterfront home on Ochlockonee Bay, private beach, fishing, dock and kayaks

6. Point & Paddle Waterfront Retreat @Alligator Point

7. 09) Queen Kitchenette by the Bay

8. Queen Kitchenette by the Bay #11

9. Cozy Panacea Retreat #3 (King)

10. Queen Kitchenette by the Bay #14

11. Cozy Panacea Retreat #7 (King)

12. Queen Kitchenette by the Bay #13

13. Perfect Panacea 1 Bedroom Apt, #2

14. Queen Kitchenette by the Bay #16

15. Queen Kitchenette by the Bay #10

16. Queen Kitchenette by the Bay #15

17. Queen Kitchenette by the Bay #8

18. Panacea Cozy Retreat #4 (DQ)

19. Panacea Cozy Retreat #6 (DQ)

20. The Best Beach-Front House “Get-A-Way” in Florida

Find vacation rentals that suit your style

Top Panacea Hotel Reviews

Great sunrise view from dining area and decks. Easy beach access.

Lighthouse- enjoy the water, bask in the view

The Panacea Motel

Hideaway Beach Cottage on waterfront with amazing views.

Happy Shack BEACH & BAY! Kayak, paddle boards, tiki hut, firepit, grille, wifi

Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +

Coastal Getaway on canal-steps to the beach

"Somewhere In The Sun" Beachfront Cottage - Old Florida Style Hideaway

Best deal at Alligator Point

Find out more about Panacea

Frequently asked questions

Go further with the Expedia app