Find hotels in Panacea, FL from ¥14,080

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Compare 425 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Shell Point Beach 2BR condo with marina views
10.0 out of 10, Exceptional, (8)
"We stayed at this property while visiting Tallahassee for an FSU game, and found this gem about 40 minutes away from the stadium. The property is at the top of what seems to be an apartment complex with about 7 other units with tenants. It is a small unit, with a very cohesive interior design with beautiful updated fixtures. The unit itself was very clean and tidy. The inside space is a bit on the small side, but there is a very good use of space. The surrounding area was very quiet and peaceful...
Shell Point Beach 2BR condo with marina views
Relax on a Beautiful River in a Natural Florida Setting
10.0 out of 10, Exceptional, (203)
"The best part of the location is that the entire property is in it's natural state. The retreat blends in with the surrounding landscape. Why anyone would cut down the trees, fill in the swamp land to build a seawall, then build a giant house and have a yard to mow is beyond me. Kudos to the owner for respecting what makes the place a beautiful place to stay."
Relax on a Beautiful River in a Natural Florida Setting
Authentic log Cabin By the Bay.
10.0 out of 10, Exceptional, (11)
"We enjoyed a memorable experience! The host Debbie was incredible in terms of attentiveness, flexibility and overall hospitality! As tournament anglers, we arrived at the property to find a pole barn style parking location for all 4 of our boats with power and water. The log cabin has a great full kitchen with an awesome bar filled with seating and an awesome den and dining room. The bedrooms were top notch! I highly recommend this property and this will be our Panacea "Go-To" place to stay!...
Authentic log Cabin By the Bay.
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Perfect Getaway
10.0 out of 10, Exceptional, (29)
"Wonderful and peaceful property. Would stay again for sure !"
Perfect Getaway
Reel Pelican Paradise located in Paradise village, Shellpoint Beach on the Gulf
10.0 out of 10, Exceptional, (54)
"Great property! Great location! Easy check-in and easy communication with property owner."
The price is ¥21,091
per night
Jun 1 - Jun 2
Reel Pelican Paradise located in Paradise village, Shellpoint Beach on the Gulf
Coastal Getaway on canal-steps to the beach
10.0 out of 10, Exceptional, (29)
"Loved the house."
Coastal Getaway on canal-steps to the beach
Enjoy Crawfordville downtown convenience at the Courtyard’s Pelican Cottage.
10.0 out of 10, Exceptional, (81)
"I really enjoyed my stay,.it was quiet and close to everything I needed. When info back to Crawfordsville I will definitely stay here again"
The price is ¥14,080
per night
Jun 3 - Jun 4
Enjoy Crawfordville downtown convenience at the Courtyard’s Pelican Cottage.
Blue Heron House, Blue Heron House
10.0 out of 10, Exceptional, (15)
"Very nice and clean. Close to the community pool and pickleball courts."
Blue Heron House, Blue Heron House
Florida Abode - Private Beach Access & Ocean Views
10.0 out of 10, Exceptional, (1)
"Clean, comfortable, and convenient condo. We hope to return soon."
Florida Abode - Private Beach Access & Ocean Views
Oyster Bay- Beautiful sunsets and spectacular birdwatching, fishing & scalloping
10.0 out of 10, Exceptional, (33)
"Amazing stay. This is the perfect spot for peace and fishing. Had an amazing stay. Host stay on site very convenient if anything is needed. The only thing if I could change is it’s a bit dated with decor etc.. but if you’re looking for a place to fish and take a break from city life. This is it!"
Oyster Bay- Beautiful sunsets and spectacular birdwatching, fishing & scalloping
Luxury Suite: * Serene Nature & Spring*!!
10.0 out of 10, Exceptional, (8)
"Great place. Host responded quickly. Beautiful property. Quiet. Loved everything."
The price is ¥19,233
per night
May 20 - May 21
Luxury Suite: * Serene Nature & Spring*!!
Old Florida Beach Bungalow
10.0 out of 10, Exceptional, (217)
"Very quaint. Perfect location. Quiet. Clean. Definitely would stay there again."
Old Florida Beach Bungalow
Hideaway Beach Cottage on waterfront with amazing views.
10.0 out of 10, Exceptional, (20)
"We really enjoyed the peaceful, quiet area of this little cottage. The owner was so very nice and she actually notified us that it was ready for check-in several hours before time. We will be returning 🙂"
Hideaway Beach Cottage on waterfront with amazing views.
Connie's Cottage- "The Hemingway" - Vintage Chic
10.0 out of 10, Exceptional, (26)
"Connie has left no stone unturned when it comes to stocking her cottage with everything you need. She graciously left us snacks which was greatly appreciated since we arrived late and we're tired so a snack and bed was perfect. Love love the tv room. Every room is decorated so charming. We will be staying again for sure. Again Thank You Connie for being such a gracious host. Harley and Patsy"
Connie's Cottage- "The Hemingway" - Vintage Chic
Wakulla River Retreat- Manatee Cottage
10.0 out of 10, Exceptional, (37)
"What a wonderful cottage! The host, Sarah, went above and beyond to welcome us and make us feel comfortable. The cottage is located in a great location close to many hotspots for birding and nature exploring. Upon arrival we were greeted with delicious homemade muffins and fresh eggs that came from the neighbor’s chickens. The cottage was very clean, comfortable, and cozy. It was fully stocked with all the necessities and much more. A canoe & kayaks were available for our use but unfortunately...
Wakulla River Retreat- Manatee Cottage
5 Bedroom Beach house 🏝 Private Beach 🏖 Sleeps 12 🎣 Fishing ☀️Screened porch
10.0 out of 10, Exceptional, (45)
"The beach house is well appointed and maintained. Everything one would need for a stay is already there (minus the food, of course). The rooms were just as shown in the pictures, clean and well organized. We enjoyed fishing off the beach; although no one swam in the water due to the murky color. In the evening we enjoyed walking on beach as the tide went out. Overall, it was a lovely time."
5 Bedroom Beach house 🏝 Private Beach 🏖 Sleeps 12 🎣 Fishing ☀️Screened porch
Waterfront Ochlockonee Bay Cottage w/ Views!
3.5 star property
10.0 out of 10, Exceptional, (2)
"We had a fabulous time here! Great cottage with a awesome view. Very relaxing!"
Waterfront Ochlockonee Bay Cottage w/ Views!
Peace on the river. Wakulla springs nearby. Wakulla River adjoins property’.
10.0 out of 10, Exceptional, (17)
"If you are looking for a wildlife retreat, believe the hype! We vist the area often to go paddling, and this will be our first choice property from now on. This modern "cabin" is a breath of fresh air. The house is a perfect blend of rustic and cosmopolitan and the property is a combination tamed and untamed which creates a wonderful haven for the local critters. In the mornings, we enjoyed sitting on the screened in porch watching and listening to nature in all her glory. We were visited by...
Peace on the river. Wakulla springs nearby. Wakulla River adjoins property’.
Timber and Tides
10.0 out of 10, Exceptional, (3)
"We absolutely loved our stay here. The entire family was able to spread out and get comfortable (you could get lost in the couch). The kitchen and bathrooms were spotless and almost luxurious. Additionally there was a nice little welcome basket when we arrived. Would have loved to have used the fit put out back but wasn’t there long enough. Unfortunately, my daughter just graduated and I won’t be coming back to Tallahassee. If I did, I would stay here when with my family or a large group."
Timber and Tides
Cabin Located in a Birding and Fishing Paradise
9.8 out of 10, Exceptional, (114)
"We stayed here for my daughter’s graduation weekend. It was close to Tally, without being in all the noise and hustle & bustle. We were able spread out, bar b que, and relax. Appointed with everything we needed. I highly recommend this for a home base for school events or just a nice getaway."
Cabin Located in a Birding and Fishing Paradise
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Where is the best place to stay in Panacea?

Based on Expedia's traveler preferences, The Panacea Motel is a top place to stay in Panacea. Other good choices for your visit include Oceanfront Retro Beach Home on the Gulf! New Windows in 2024 to Enjoy the Views and Old Florida Beach Bungalow. See all available top hotels, or vacation rentals in Panacea.

What's the top vacation rental in Panacea?

Old Florida Beach Bungalow: Visitors give good reviews to this Panacea vacation home rental, which is located near the beach and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. You and your friends and family can relax into your vacation with amenities like a selection of books. Other favorite homes for rent in Panacea are Oceanfront Retro Beach Home on the Gulf! New Windows in 2024 to Enjoy the Views and BEACHFRONT! Summer Weeks Available! Million Dollar view from EVERY Room! . See all vacation rentals in Panacea.

If I need to cancel my hotel reservation in Panacea, will I receive a refund?

Yes! Most hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Panacea.

Where can I learn more about changing or cancelling my trip to Panacea?

For more details about changing or cancelling your trip to Panacea, click here.

What's the best pet-friendly place to stay in Panacea?

The Panacea Motel is a top pet-friendly option for your stay. See more pet-friendly hotel accommodations in Panacea.

Where is the best hotel to stay with easy access to USS Mohawk CGC Veterans Memorial Reef?

Best Western Wakulla Inn & Suites is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. You'll find it 5.7 mi (9.1 km) from USS Mohawk CGC Veterans Memorial Reef. Another good option is Magnuson Hotel Wildwood Inn, located 6.5 mi (10.5 km) away.

What are some accommodations with pools in Panacea?

Waterfront Oasis with Pool, Golf Cart, Tennis Court & Lots of Free Amenities: Offers sun loungers, a communal pool, and complimentary wireless internet access. View all hotels with pools in Panacea.

What is the best spa hotel in Panacea?
What's the best hotel for staying near Tallahassee Regional Airport (TLH)?

Tallahassee Sun & Moon is one of the top choices for your stay and is a popular property, featuring free WiFi and free parking. It's located 3.5 mi (5.7 km) from Tallahassee Regional Airport. Other options close to the airport include Hampton Inn & Suites Tallahassee Capitol-University and Governors Inn.

What's it like to stay in Panacea?

Nature enthusiasts will enjoy exploring Panacea, and many visitors are sure to appreciate the beaches and seafood restaurants. The relaxing and tucked away setting also entices those visiting the city. In Panacea, there are 158 hotels and other accommodations to choose from. Find out more about Panacea.

What are the top places to visit in Panacea?

Natural beauty is on display at Mashes Sand Beach, Alligator Point Beach, and Bald Point State Park. Dolphin watching is a great activity, and Bayside Marina is one place to visit. A couple of additional sights to add to your agenda are Gulf Specimen Public Aquarum and USS Mohawk CGC Veterans Memorial Reef. Check out what more to see and do in Expedia's Panacea guide.

What's the seasonal weather like in Panacea?

The hottest months are usually July and August with an average temp of 81°F, while the coldest months are January and February with an average of 58°F. The rainiest months in Panacea are August, July, June, and September, with each month seeing an average of 8 inches of rainfall.