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Find hotels in Panacea, FL from ￥14,970

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Stay near popular Panacea attractions

Alligator Point Beach

3.5/5 (2 reviews)
Escape to this pristine stretch of old coastal Florida with white sands and shallow, clear waters. Spot dolphins and sea turtles while enjoying the serenity of an undeveloped shoreline.
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Bald Point State Park

4.6/5 (9 reviews)
Where Ochlockonee Bay meets Apalachee Bay, this coastal park showcases diverse ecosystems from beaches to pine flatwoods. Spot migrating raptors and monarch butterflies while hiking through pristine natural habitats.
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Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

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Sunset over a lake at Panacea, northern Florida, USA | NONE |

Top Panacea Hotel Reviews

Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +

Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +

10/10 Excellent
"Great place!! Owner was super communicative. Loved the golf cart and beach. We will def be back! Thank you!"
cheryl b. 7-night trip
Posted 3 days ago
Private Beachfront w/ Sauna, Hottub, Golf Cart, Kayaks, Paddle Boards & Bikes +

More cheap stays in Panacea

Franklin Inn

Franklin Inn

1589 US-98 Carrabelle FL
The price is ￥13,547 per night from Jan 4 to Jan 5
￥13,547
￥14,970 total
Jan 4 - Jan 5, 2026
includes taxes & fees
7.8/10 Good! (456 reviews)

Frequently asked questions

Where is the best place to stay in Panacea?
Based on Expedia's traveler preferences, The Panacea Motel is a top place to stay in Panacea. Other good choices for your visit include Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock and "Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8. See all available top hotels, or vacation rentals in Panacea.
What's the top vacation rental in Panacea?
Oceanfront on a Private Beach-Hot Tub-Beautifully Remodeled-Dog Friendly Beach: Visitors give good reviews to this Panacea vacation home rental, which is located on the beach and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a garden, a selection of games, and a hot tub so you can immerse yourself in your vacation. Other favorite homes for rent in Panacea are Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock and NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!. See all vacation rentals in Panacea.
If I need to cancel my hotel reservation in Panacea, will I receive a refund?
Yes! Most hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Panacea.
Where can I learn more about changing or cancelling my trip to Panacea?
For more details about changing or cancelling your trip to Panacea, click here.
What's the best pet-friendly place to stay in Panacea?
The Panacea Motel is a top pet-friendly option for your stay. See more pet-friendly hotel accommodations in Panacea.
What are some accommodations with pools in Panacea?
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front: Offers complimentary wireless internet access, a pool, and kitchens. View all hotels with pools in Panacea.
What's the best hotel for staying near Tallahassee Regional Airport (TLH)?
Tallahassee Sun & Moon is one of the top choices for your stay and is a popular property, featuring free WiFi and free parking. It's located 3.5 mi (5.7 km) from Tallahassee Regional Airport. Other options close to the airport include Hampton Inn & Suites Tallahassee Capitol-University and Governors Inn.
What's it like to stay in Panacea?
Nature enthusiasts will enjoy exploring Panacea, and many visitors are sure to appreciate the beaches and seafood restaurants. The relaxing and tucked away setting also entices those visiting the city. In Panacea, there are 213 hotels and other accommodations to choose from. Find out more about Panacea.
What are the top places to visit in Panacea?
Natural beauty is on display at Mashes Sand Beach, Alligator Point Beach, and Bald Point State Park. Dolphin watching is a great activity, and Bayside Marina is one place to visit. A couple of additional sights to add to your agenda are Wilson Beach and Alligator Harbor Aquatic Preserve. Check out what more to see and do in Expedia's Panacea guide.
What's the seasonal weather like in Panacea?
The hottest months are usually July and August with an average temp of 81°F, while the coldest months are January and February with an average of 58°F. The rainiest months in Panacea are August, July, June, and September, with each month seeing an average of 8 inches of rainfall.

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