A marshy landscape with water, trees, and a distant city skyline.

Search Vacation Homes in Ladys Island

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Ladys Island vacation homes

Edisto Island Oasis

Edisto Island Oasis
Edisto Island
8.0 out of 10, Very Good, (1 review)
"Really appreciated how clean the inside was. Very close to Botany Bay, Flowers Seafood, Serpentarium, and Nature center"
United States
joyce m.
The price is ¥29,525
¥82,845 total
includes taxes & fees
Jul 13 - Jul 14
Edisto Island Oasis

Historic Boutique Hotel Suite w. Waterviews!

Historic Boutique Hotel Suite w. Waterviews!
Historic District
10.0 out of 10, Exceptional, (1 review)
"This property was managed very well and we enjoyed our stay. The bed was comfortable, there were plenty of towels etc in the bathroom and the AC kept up with the SC heat and humidity. We took advantage of the rockers on the big porch both in the mornings and again in the evenings. It’s about a 8 min leisurely walk (walking shoes recommended since there’s lots of construction in Beaufort right now) to the waterfront shops and restaurants and there’s a cute breakfast/lunch bakery right next door....
United States
Elizabeth N.
Historic Boutique Hotel Suite w. Waterviews!

"A" Secluded Quiet Oasis Treehouse w/ Beach Pass

"A" Secluded Quiet Oasis Treehouse w/ Beach Pass
Saint Helena Island
10.0 out of 10, Exceptional, (15 reviews)
"We were very pleased with our stay. The host had every thing set up for us and was very helpful! We will come again for sure!"
United States
Darlene S.
The price is ¥28,235
¥53,065 total
includes taxes & fees
Jul 12 - Jul 13
"A" Secluded Quiet Oasis Treehouse w/ Beach Pass

Mid-Island Retreat | Pool | Beach Gear | Pets OK

Mid-Island Retreat | Pool | Beach Gear | Pets OK
Mid Island
The price is ¥15,973
¥45,579 total
includes taxes & fees
Jul 6 - Jul 7
Mid-Island Retreat | Pool | Beach Gear | Pets OK

Sleeps 10•5 Beds•3 min to DT Beaufort•12 min to Parris Island 🇺🇸•Shaded Deck

Sleeps 10•5 Beds•3 min to DT Beaufort•12 min to Parris Island 🇺🇸•Shaded Deck
Northwest Quadrant
10.0 out of 10, Exceptional, (37 reviews)
"Yes plenty to do and a lot of fun"
United States
Christopher C.
The price is ¥16,466
¥53,782 total
includes taxes & fees
Jul 7 - Jul 8
Sleeps 10•5 Beds•3 min to DT Beaufort•12 min to Parris Island 🇺🇸•Shaded Deck

Pinky's Palace - Cozy Bungalow minutes from Parris Island

Pinky's Palace - Cozy Bungalow minutes from Parris Island
Port Royal
9.0 out of 10, Wonderful, (2 reviews)
"Cute cottage and good location. Kitchen equipped well and nicely decorated.Close to Spanish Moss Trail and Cypress Wetlands.Very good communication with owner."
United States
Debbie S.
The price is ¥25,371
¥60,032 total
includes taxes & fees
Jul 6 - Jul 7
Pinky's Palace - Cozy Bungalow minutes from Parris Island

Coastline Cottage with Breathtaking Ocean Views On Fripp Island Wi-Fi, Golf Cart

Coastline Cottage with Breathtaking Ocean Views On Fripp Island Wi-Fi, Golf Cart
Saint Helena Island
10.0 out of 10, Exceptional, (35 reviews)
"Wonderful ocean views. Beautiful beaches. The best of the barrier islands. Right next to a state park with a lighthouse and great hiking. Would definitely recommend!!"
United States
Christopher B.
The price is ¥45,982
¥88,205 total
includes taxes & fees
Jul 20 - Jul 21
Coastline Cottage with Breathtaking Ocean Views On Fripp Island Wi-Fi, Golf Cart

Enjoy 15 percent off a week stay! Exquisite villa 10 minutes from the beach!

Enjoy 15 percent off a week stay! Exquisite villa 10 minutes from the beach!
Dataw Island, US
8.8 out of 10, Excellent, (20 reviews)
"The condo needed coffee filters otherwise no problems. Beautiful view."
United States
Peggy D.
The price is ¥38,560
¥98,853 total
includes taxes & fees
Jul 7 - Jul 8
Enjoy 15 percent off a week stay! Exquisite villa 10 minutes from the beach!

On Island Pool, pet friendly, free tennis andparking

On Island Pool, pet friendly, free tennis andparking
Mid Island
8.0 out of 10, Very Good, (2 reviews)
"Had a great time, very nice inside!"
United States
teri q.
The price is ¥17,967
¥46,944 total
includes taxes & fees
Jul 6 - Jul 7
On Island Pool, pet friendly, free tennis andparking

The Offbeat Oasis by the Marsh- State Park Pass Included🏖

The Offbeat Oasis by the Marsh- State Park Pass Included🏖
Saint Helena Island
9.8 out of 10, Exceptional, (18 reviews)
"Beautiful marsh views. Close to the beach and state park. Peaceful and well taken care of. "
United States
Dorothy T.
The price is ¥29,848
¥60,874 total
includes taxes & fees
Jul 6 - Jul 7
The Offbeat Oasis by the Marsh- State Park Pass Included🏖

185 Beach Club Villa

185 Beach Club Villa
Fripp Island
The price is ¥35,172
¥106,496 total
includes taxes & fees
Aug 2 - Aug 3
185 Beach Club Villa

Historic Beaufort, South Carolina Near Hilton Head, SC, New Renovation, Sleeps 8

Historic Beaufort, South Carolina Near Hilton Head, SC, New Renovation, Sleeps 8
Beaufort
8.8 out of 10, Excellent, (18 reviews)
"This was our 2nd stay at this property so there we no surprises. The home is comfortable with plenty of room for a larger family. It has everything you need and is close to Beaufort. "
United States
Faye B.
The price is ¥24,685
¥40,996 total
includes taxes & fees
Jul 12 - Jul 13
Historic Beaufort, South Carolina Near Hilton Head, SC, New Renovation, Sleeps 8

Marshfront Villa In The Trees - Near Beach & Bay

Marshfront Villa In The Trees - Near Beach & Bay
Edisto Island
The price is ¥64,789
¥120,088 total
includes taxes & fees
Jul 7 - Jul 8
Marshfront Villa In The Trees - Near Beach & Bay

4 mi. to Beaufort Waterfront and Parris Island 🇺🇸- 🧲 Pit - Porch w/ Grill

4 mi. to Beaufort Waterfront and Parris Island 🇺🇸- 🧲 Pit - Porch w/ Grill
Port Royal
9.4 out of 10, Exceptional, (16 reviews)
"Enjoyed our stay. Nice place to gather with family. Thank you. "
United States
Elise A.
4 mi. to Beaufort Waterfront and Parris Island 🇺🇸- 🧲 Pit - Porch w/ Grill

Walk to the Beach! Firepit, games, pets welcome, bring your boat!

Walk to the Beach! Firepit, games, pets welcome, bring your boat!
Edisto Beach
9.8 out of 10, Exceptional, (29 reviews)
"Very clean and inviting "
United States
denny m.
The price is ¥56,469
¥103,180 total
includes taxes & fees
Jul 12 - Jul 13
Walk to the Beach! Firepit, games, pets welcome, bring your boat!

Beach Belle- Pet Friendly- Luxury Edisto Home

Beach Belle- Pet Friendly- Luxury Edisto Home
Edisto Beach
The price is ¥49,536
¥126,608 total
includes taxes & fees
Jul 12 - Jul 13
Beach Belle- Pet Friendly- Luxury Edisto Home

Stunning Sea Pines Treetop Oasis Deck & Grill with short walk to Harbourtown

Stunning Sea Pines Treetop Oasis Deck & Grill with short walk to Harbourtown
Sea Pines
10.0 out of 10, Exceptional, (101 reviews)
"Our stay here was excellent! The home is so nice and tucked away in a cozy area with plenty in walking distance. We had a beautiful stay here and will certainly stay again! "
United States
Daniel G.
The price is ¥29,186
¥67,069 total
includes taxes & fees
Jul 8 - Jul 9
Stunning Sea Pines Treetop Oasis Deck & Grill with short walk to Harbourtown

Spanish Moss Oasis by Port Royal Landing Marina

Spanish Moss Oasis by Port Royal Landing Marina
Port Royal Landing
9.6 out of 10, Exceptional, (7 reviews)
"Great house and location. Wonderful host!"
United States
Bree C.
The price is ¥37,915
¥76,266 total
includes taxes & fees
Jul 7 - Jul 8
Spanish Moss Oasis by Port Royal Landing Marina

Tucked Away Renovated 4 Bedroom/ 2 Bath, Sleep 12 Close to Parris Island

Tucked Away Renovated 4 Bedroom/ 2 Bath, Sleep 12 Close to Parris Island
Beaufort
8.6 out of 10, Excellent, (7 reviews)
"The check in process was easy and the owner is very friendly. However we had no idea it was a trailer park. The yard is full clutter and the other mobile homes are too close to the house. The couch and the bed were horrible! We could feel the springs in the cushions and the washer and dryer clearly need to be replaced. The dryer didn't dry. The stay was short and it didn't rain but rain would have been mud puddles. All in all the description of the property feels a little crafted and what we got...
United States
Kijana A.
The price is ¥26,137
¥42,771 total
includes taxes & fees
Jul 6 - Jul 7
Tucked Away Renovated 4 Bedroom/ 2 Bath, Sleep 12 Close to Parris Island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Ladys Island Hotel Reviews

Find out more about Ladys Island

Ladys Island Vacation Homes information

Number of reviews
309
Accommodation
841 Vacation Homes
Lowest Price
¥40,996
Highest Price
¥126,608

Explore a world of travel with Expedia