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Find hotels in Downtown Clayton, St. Louis from ￥15,202

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Discover 1,737 Downtown Clayton hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Clayton Plaza Hotel & Extended Stay
Exterior

Clayton Plaza Hotel & Extended Stay

3.5 star property
8.8 out of 10, Excellent, (2989)
"Great staff and hotel!"
The price is ￥15,177
￥17,679 total
includes taxes & fees
Oct 12 - Oct 13
Clayton Plaza Hotel & Extended Stay
AC Hotel St. Louis Clayton
2 bars/lounges, rooftop bar

AC Hotel St. Louis Clayton

3.0 star property
9.2 out of 10, Wonderful, (187)
"Enjoyed my stay"
The price is ￥20,655
￥24,062 total
includes taxes & fees
Oct 12 - Oct 13
AC Hotel St. Louis Clayton
Le Méridien St. Louis Clayton
Outdoor pool, open 8:00 AM to 8:30 PM, pool umbrellas, sun loungers

Le Méridien St. Louis Clayton

4.0 star property
8.8 out of 10, Excellent, (659)
"The room was clean and service was excellent."
The price is ￥24,471
￥28,752 total
includes taxes & fees
Oct 12 - Oct 13
Le Méridien St. Louis Clayton
The Ritz-Carlton, St. Louis
Meeting facility

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (550)
"Service is exceptional!!!"
The price is ￥93,469
￥108,883 total
includes taxes & fees
Oct 2 - Oct 3
The Ritz-Carlton, St. Louis
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Property entrance

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

3.5 star property
8.4 out of 10, Very Good, (573)
"Staff was excellent and the court yard was a wonderful place to sit and have a glass of wine. The upscale bathroom is off the charts! "
The price is ￥18,129
￥22,523 total
includes taxes & fees
Oct 5 - Oct 6
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Drury Plaza Hotel St. Louis at the Arch
Rooftop terrace

Drury Plaza Hotel St. Louis at the Arch

3.0 star property
9.4 out of 10, Exceptional, (3118)
"Great staff and food "
The price is ￥17,831
￥20,850 total
includes taxes & fees
Oct 5 - Oct 6
Drury Plaza Hotel St. Louis at the Arch
Pear Tree Inn St. Louis Airport
Lobby

Pear Tree Inn St. Louis Airport

2.5 star property
9.4 out of 10, Exceptional, (2700)
"Nice place to stay "
The price is ￥13,373
￥15,743 total
includes taxes & fees
Oct 20 - Oct 21
Pear Tree Inn St. Louis Airport
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Lobby sitting area

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3.0 star property
8.2 out of 10, Very Good, (1043)
"The staff was nice, breakfast was good, the location was convenient. "
The price is ￥13,263
￥15,318 total
includes taxes & fees
Oct 1 - Oct 2
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Drury Inn & Suites St. Louis Union Station
Indoor pool

Drury Inn & Suites St. Louis Union Station

3.0 star property
9.4 out of 10, Exceptional, (1265)
" Love staying here!"
The price is ￥17,682
￥21,028 total
includes taxes & fees
Oct 13 - Oct 14
Drury Inn & Suites St. Louis Union Station
Hyatt Regency St. Louis at The Arch
Lobby

Hyatt Regency St. Louis at The Arch

4.0 star property
8.4 out of 10, Very Good, (4039)
"Great location and friendly staff!"
The price is ￥18,575
￥21,906 total
includes taxes & fees
Oct 2 - Oct 3
Hyatt Regency St. Louis at The Arch
Moonrise Hotel
Exterior

Moonrise Hotel

4.0 star property
9.0 out of 10, Wonderful, (1914)
"Cool place."
The price is ￥21,184
￥25,196 total
includes taxes & fees
Oct 6 - Oct 7
Moonrise Hotel
The Wildwood Hotel
Ballroom

The Wildwood Hotel

3.5 star property
9.2 out of 10, Wonderful, (1605)
"We enjoyed our stay!"
The Wildwood Hotel
21C Museum Hotel St Louis
Interior

21C Museum Hotel St Louis

4.5 star property
9.0 out of 10, Wonderful, (1393)
"Wonderful stay! "
The price is ￥23,627
￥28,369 total
includes taxes & fees
Oct 1 - Oct 2
21C Museum Hotel St Louis
Wingate by Wyndham St. Louis Airport
Room, 2 Queen Beds, Accessible, Non Smoking (Mobility, Tub W/Grab Bars) | Desk, laptop workspace, iron/ironing board, free cribs/infant beds

Wingate by Wyndham St. Louis Airport

2.5 star property
9.2 out of 10, Wonderful, (1434)
"The staff was very friendly"
The price is ￥17,000
￥20,016 total
includes taxes & fees
Oct 6 - Oct 7
Wingate by Wyndham St. Louis Airport
Embassy Suites by Hilton St. Louis Downtown
Exterior

Embassy Suites by Hilton St. Louis Downtown

4.0 star property
8.8 out of 10, Excellent, (1233)
"Clean quiet rooms and friendly staff!"
The price is ￥17,270
￥20,539 total
includes taxes & fees
Oct 12 - Oct 13
Embassy Suites by Hilton St. Louis Downtown
Sonesta ES Suites St. Louis - Chesterfield
Front of property

Sonesta ES Suites St. Louis - Chesterfield

3.0 star property
8.0 out of 10, Very Good, (1019)
"Very nice place"
The price is ￥12,929
￥14,996 total
includes taxes & fees
Oct 6 - Oct 7
Sonesta ES Suites St. Louis - Chesterfield
Live by Loews - St.Louis
Breakfast, lunch and dinner served

Live by Loews - St.Louis

4.0 star property
9.2 out of 10, Wonderful, (1062)
"Incredible hotel! "
The price is ￥25,113
￥29,866 total
includes taxes & fees
Oct 5 - Oct 6
Live by Loews - St.Louis
Travelodge by Wyndham St. Louis
Exterior

Travelodge by Wyndham St. Louis

2.0 star property
6.6 out of 10, (1031)
"Just did an overnight stay and everything was great! "
The price is ￥9,458
￥11,191 total
includes taxes & fees
Oct 19 - Oct 20
Travelodge by Wyndham St. Louis
River City Casino & Hotel
Daily cooked-to-order breakfast for a fee

River City Casino & Hotel

4.0 star property
9.0 out of 10, Wonderful, (1401)
"Place was nice and staff was very friendly "
The price is ￥13,075
￥17,377 total
includes taxes & fees
Oct 19 - Oct 20
River City Casino & Hotel
Pear Tree Inn St. Louis Arnold
Lobby

Pear Tree Inn St. Louis Arnold

2.5 star property
9.2 out of 10, Wonderful, (1018)
"Clean, comfortable and pleasant stay."
The price is ￥13,373
￥15,458 total
includes taxes & fees
Oct 6 - Oct 7
Pear Tree Inn St. Louis Arnold
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Downtown Clayton

Find the best Downtown Clayton areas and neighborhoods for the activities you enjoy most.
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Central West End

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

Top Downtown Clayton Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent
"Great location and such a comfortable sleep!"
Anne 1-night trip
Posted 17 hours ago
Pear Tree Inn St. Louis Near Union Station

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Downtown Clayton?

Travelers to the Downtown Clayton neighborhood in St. Louis will be sure to enjoy their stay.

What's a favorite place to stay in Downtown Clayton?

Based on Expedia customer reviews, AC Hotel St. Louis Clayton is the highest ranked property in Downtown Clayton. This hotel offers 2 restaurants and 2 bars. Other favorite options in the area include The Ritz-Carlton, St. Louis and Le Méridien St. Louis Clayton.

How many hotels should I expect to find in the Downtown Clayton area?

Expedia has 6 Downtown Clayton hotels and other accommodations, and one might make a good home base for venturing out into the greater St. Louis area.

If I need to cancel my hotel reservation in Downtown Clayton, will I receive a refund?

Yes! Most hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then you can use the "fully refundable" filter to view top deals in Downtown Clayton.

Where can I learn more about changing or cancelling my trip to Downtown Clayton?

For more details about rescheduling or cancelling your trip to Downtown Clayton, go to https://www.expedia.com/service/.

What can I see and do in this St. Louis neighborhood?

Shaw Park Tennis Center, Saint Louis Galleria Mall, and Tao Tennis Center are just a few of the places to visit in and around Downtown Clayton. While you're out sightseeing, Center of Creative Arts and Chapel of St. Timothy And St. Titus, Concordia Seminary are a couple of additional sights to visit in St. Louis.

How can I get around Downtown Clayton and the greater St. Louis area?

Ready to get out and explore the city? Clayton Station is the closest metro station.