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Find hotels in Downtown Clayton, St. Louis
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Our top choices for Downtown Clayton hotels
8.8 out of 10, Excellent, (3045)
"Great stay‼️"
Calvin
The price is ￥14,693
￥17,153 total
includes taxes & fees
Jan 30 - Jan 31, 2026
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Seven Gables, St. Louis West, a Tribute Portfolio HotelDowntown Clayton
8.4 out of 10, Very Good, (577)
"Love this place."
Robert
The price is ￥20,486
￥25,403 total
includes taxes & fees
Jan 4 - Jan 5, 2026
8.8 out of 10, Excellent, (681)
"The gym was amazing! "
Hannah
The price is ￥21,087
￥24,829 total
includes taxes & fees
Jan 3 - Jan 4, 2026
9.0 out of 10, Wonderful, (230)
"Staff was amazing "
Sham
The price is ￥20,329
￥23,731 total
includes taxes & fees
Jan 25 - Jan 26, 2026
9.2 out of 10, Wonderful, (554)
"The stay was ok even though nothing was explained to be. The hours of restaurant, where the gym is located about the bar in the room nothing. "
Shemelle
The price is ￥77,829
￥90,856 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The ArchDowntown St. Louis, 13.2 km from Downtown Clayton
8.4 out of 10, Very Good, (4032)
"Staff was supper nice and it all went so smooth."
Brayden
The price is ￥20,173
￥23,790 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Downtown Clayton
Find the best Downtown Clayton areas and neighborhoods for the activities you enjoy most.
Downtown St. Louis
Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Busch Stadium or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.
Berkeley
Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.
Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.
St. Charles Historic District
Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
Top Downtown Clayton Hotel Reviews
Hyatt Regency St. Louis at The Arch
10/10 Excellent
Frequently asked questions
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