Luxury Hotels in South America from ￥34,305
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on South America Luxury Hotels
Our top choices for South America luxury hotels
1. Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
Hotel das Cataratas, A Belmond Hotel, Iguassu FallsFoz do Iguaçu
10.0 out of 10, 1002, (1,002 reviews)
- Exclusive park access and stunning Iguazu Falls views unite with full-service spa treatments at this luxurious Belmond retreat.
The price is ￥110,983
￥128,467 total
includes taxes & fees
Sep 18 - Sep 19
9.4 out of 10, 677, (677 reviews)
- Intimate Buenos Aires boutique hotel offers deep soaking tubs, full-service spa treatments, and garden-view fine dining in Recoleta.
The price is ￥33,844
￥34,305 total
Sep 15 - Sep 16
3. Palacio del Inka, A Luxury Collection Hotel by Marriott
Palacio del Inka, A Luxury Collection Hotel by MarriottCusco Historic Center
9.6 out of 10, 1003, (1,003 reviews)
- Opulent Peruvian palace with full-service spa offers historic luxury and pampering treatments in the heart of ancient Cusco.
The price is ￥48,180
￥59,354 total
Oct 12 - Oct 13
9.4 out of 10, 261, (261 reviews)
- Art deco elegance defines this Buenos Aires retreat with pool, sauna, and premium bedding in El Centro.
5. Hotel Paracas, a Luxury Collection Resort, Paracas
Hotel Paracas, a Luxury Collection Resort, ParacasParacas
9.4 out of 10, 793, (793 reviews)
- Indulge in beachfront luxury at this Paracas resort featuring a full-service spa and 2 ocean pools.
The price is ￥33,042
￥36,346 total
Oct 4 - Oct 5
9.6 out of 10, 1003, (1,003 reviews)
- Indulge in 5-star opulence at this Buenos Aires hotel with private hot tubs, poolside service, and a full-service spa.
The price is ￥59,969
￥60,430 total
Sep 29 - Sep 30
9.6 out of 10, 1001, (1,001 reviews)
- Historic luxury in the heart of Cusco with an indulgent spa, indoor pool, and five-star service just steps from Plaza de Armas.
The price is ￥51,613
￥63,072 total
Oct 5 - Oct 6
9.6 out of 10, 774, (774 reviews)
- Indulge in spa serenity at this luxury Santiago hotel, where rooftop dining meets downtown elegance.
The price is ￥41,475
￥41,475 total
Sep 27 - Sep 28
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top South America Hotel Reviews
NH Buenos Aires Tango
10/10 Excellent
Explore a world of travel with Expedia
- Gay friendly Hotels in Brasília
- Brasília Hotels
- Buenos Aires Hotels
- Gay friendly Hotels in Cali
- Adults Only Resorts & in Cartagena
- All-Inclusive Hotel Hotels in Cartagena
- Hotels with Bars in Cartagena
- Beach Hotels in Cartagena
- Boutique Hotels in Cartagena
- Cheap Hotels in Cartagena
- Hotels with a Lazy River in Cartagena
- Hotels with Hot Tubs in Cartagena
- Gay friendly Hotels in Cartagena
- Luxury Hotels in Cartagena
- Romantic Hotels in Cartagena
- Cusco Hotels
- Adventure Hotels in Colombia
- All-Inclusive Hotel Hotels in Colombia
- Hotels with Bars in Colombia
- Boutique Hotels in Colombia
- Business Hotels in Colombia
- Casino Hotels in Colombia
- Family Hotels in Colombia
- Golf Hotels in Colombia
- Green Hotels in Colombia
- Historic Hotels in Colombia
- Hotel with a Concierge Hotels in Colombia
- Hotels with Early Check-in in Colombia
- Hotels with a Pool in Colombia
- Gay friendly Hotels in Fernando de Noronha
- Gay friendly Hotels in Gramado
- Gramado Hotels
- Gay friendly Hotels in João Pessoa
- Gay friendly Hotels in Lima
- Hotels with Hot Tubs in Maceió
- Gay friendly Hotels in Maceió
- Adults Only Resorts & in Machu Picchu
- Hotels with Bars in Machu Picchu
- Hotels with WiFi in Machu Picchu
- Hotels with smoking rooms in Machu Picchu
- Gay friendly Hotels in Machu Picchu
- Pet-Friendly Hotels in Machu Picchu
- Medellín Hotels
- Gay friendly Hotels in Paipa
- Gay friendly Hotels in Puerto Iguazú
- Luxury Hotels in Puerto Iguazú
- Gay friendly Hotels in Recife
- Family Hotels in Rio de Janeiro
- Hotel Wedding Venues Hotels in Rio de Janeiro
- Boutique Hotels in San Andrés
- Hotels with Waterslides in San Andrés
- Gay friendly Hotels in San Andrés
- Gay friendly Hotels in San Carlos de Bariloche
- Gay friendly Hotels in San Pedro de Atacama
- Beach Hotels in Santa Marta
- Cheap Hotels in Santa Marta
- Gay friendly Hotels in Santa Marta
- São Paulo Hotels
- Gay friendly Hotels in Villa de Leyva
- Visit Angra dos Reis
- Visit Arraial do Cabo
- Visit Bogotá
- Visit Brasília
- Visit Buenos Aires
- Visit Cabo Frio
- Cartagena Vacations
- Visit Cartagena
- Colombia Vacations
- Visit Curitiba
- Visit Florianópolis
- Visit Fortaleza
- Visit Maceió
- Machu Picchu Vacations
- Medellín Vacations
- Visit Medellín
- Visit Montevideo
- Rio de Janeiro Vacations
- Santa Marta Vacations
- Visit Santa Marta
- Tristan da Cunha Vacations
- Visit Tristan da Cunha
- Visit Vina del Mar