Photo by PhotoJoy
Resorts & Hotels with Spas in Panama from ￥18,590
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Panama Resorts & Hotels with Spas
Our top choices for Panama hotels with a spa
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Sortis Hotel, Spa & Casino, Autograph Collection by MarriottBella Vista
8.8 out of 10, Excellent, (1,006 reviews)
"Greatttt stay"
Devdutt
The price is ￥24,653
￥27,118 total
includes taxes & fees
Mar 8 - Mar 9
8.6 out of 10, Excellent, (2,446 reviews)
"Very friendly staff, impeccable room, free airport shuttle, nice food..... we had a great stay!"
Renildis
The price is ￥18,482
￥20,330 total
includes taxes & fees
Mar 5 - Mar 6
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama CityJuan Diaz
9.6 out of 10, Exceptional, (666 reviews)
"As usual the stay was amazing in this hotel"
Jose
The price is ￥41,747
￥45,922 total
includes taxes & fees
Mar 7 - Mar 8
9.0 out of 10, Wonderful, (1,011 reviews)
"Good room, good breakfast, friendly staff"
Bret
The price is ￥24,963
￥27,459 total
includes taxes & fees
Mar 1 - Mar 2
9.4 out of 10, Exceptional, (1,003 reviews)
"All was perfect for our Christmas vacation - staff food and rooms - would definitely stay here again"
PROBIR MAYUR
The price is ￥32,289
￥35,519 total
includes taxes & fees
Mar 15 - Mar 16
8.2 out of 10, Very Good, (869 reviews)
"Staff was very friendly and accommodating. I really enjoyed the breakfast."
Helene
The price is ￥16,900
￥18,590 total
includes taxes & fees
Mar 13 - Mar 14
9.8 out of 10, Exceptional, (598 reviews)
"Beautiful place"
Jose
The price is ￥59,966
￥65,963 total
includes taxes & fees
Feb 24 - Feb 25
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Panama Hotel Reviews
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
10/10 Excellent
Explore a world of travel with Expedia
- Hostels in Santiago
- Resorts & Hotels with Spas in Panama City
- Resorts in Guna Yala
- Aparthotels in La Laguna
- Aparthotels in Los Angeles
- Lodges in San Blas Islands
- B&B in La Loma
- Resorts in Maria Chiquita
- Panama City Hotels
- Romantic Hotels in San Jose
- Business Hotels in Bugaba
- Luxury Hotels in Buena Vista
- Guest Houses in Herrera
- Resorts in Narganá
- Cheap Hotels in Boquete
- San Jose Hotels
- Resorts in Coco Key
- Cheap Hotels in Los Angeles
- Pet-Friendly Hotels in San Carlos
- Santa Clara Hotels
- Adults Only Resorts & in Panamá Province
- Historic Hotels in Boca Chica
- Beach Hotels in Boca Chica
- Cheap Hotels in Frances
- Lodges in La Laguna
- Ranches in Bocas del Toro Province
- Aparthotels in Panama City
- Cheap Hotels in Santa Catalina
- Cheap Hotels in Nata
- B&B in Sorá
- Resorts in San Blas Islands
- Luxury Hotels in Río Sereno
- Tocumen Hotels
- San Blas Islands Hotels
- Scuba Diving Hotels in Panama City
- Resorts in La Loma
- B&B in Narganá
- Family Hotels in Anton
- Panamá Province Hotels
- Villas in Colón
- Resorts in Los Angeles
- Hostels in Sorá
- Luxury Hotels in Los Angeles
- Guest Houses in Sorá
- Resorts in Boquete
- B&B in Bugába
- Cheap Hotels in Palenque
- Resorts in La Laguna
- Resorts in Buenaventura
- Luxury Hotels in Santa Catalina
- Los Angeles Hotels
- Resorts in Bugába
- Adults Only Resorts & in Panama City
- Luxury Hotels in Coco Key
- Guna Yala Hotels
- Beach Hotels in Bocas del Toro
- Hostels in San Blas Islands
- Resorts in San Juan Bautista
- Residences in Los Naranjos
- Beach Hotels in Bugaba
- Isla Grande Hotels
- Beach Hotels in La Arena
- Cheap Hotels in Guna Yala
- Santiago Hotels
- Hotels with a Pool in Panama City
- All-Inclusive Hotel Hotels in Bugaba
- Nata Hotels
- Villas in Los Angeles
- Adults Only Resorts & in Bocas del Toro Province
- Resorts in Isla Grande
- Aparthotels in Panamá Province
- Boquete Hotels
- Beach Hotels in Rio Hato
- Cheap Hotels in La Laguna
- Cheap Hotels in San Carlos
- Luxury Hotels in Panama City
- Resorts & Hotels with Spas in Bugaba
- Hostels in Nata
- Resorts in Bugaba
- Resorts in Rio Hato
- La Laguna Hotels
- All-Inclusive Hotel Hotels in Cambutal
- Beach Hotels in Panama City
- Ranches in Bugaba
- Cheap Hotels in Panama City
- Hostels in Bocas del Toro Province
- Luxury Hotels in Bugaba
- Shopping Hotels in Santa Clara
- Resorts in Bocas del Toro Province
- All-Inclusive Hotel Hotels in Rio Hato
- Capsule Hotels in Narganá
- Capsule Hotels in Coclé
- Sorá Hotels
- Hotels with Early Check-in in Panama City