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Florence County
South Carolina
United States of America
Hotels
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Vacation Rentals in Florence County Car Rentals in Florence County Florence County Travel Guide

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Top Cities in Florence County

A historic brick building with arched windows and a river in the foreground.

A sunset over a forested landscape with a river and a parking lot.

A person walking on a rope bridge surrounded by dense forest.

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Oct 10 - Oct 11

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Oct 16 - Oct 18

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Oct 23 - Oct 25

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Our top choices for Florence County hotels

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.

A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.

A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.

1. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 star property

Florence

9.0 out of 10, Wonderful, (2,463 reviews)

9.0/10

Wonderful

(2,463 reviews)

"Great location, friendly staff."

"Great location, friendly staff."

United States

Windia

The price is ￥14,100

￥14,100

￥15,792 total

includes taxes & fees

Oct 18 - Oct 19

Park Inn by Radisson Florence, SC

A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.

A modern cafeteria with long wooden tables, green chairs, and yellow accents.

A hotel room with two beds, a desk with a chair, a television, and a window with curtains.

An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.

2. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 star property

Florence

8.2 out of 10, Very good, (315 reviews)

8.2/10

Very good

(315 reviews)

"The staff was great and the room was clean! Great pit stop on our way to Disney!"

"The staff was great and the room was clean! Great pit stop on our way to Disney!"

United States

Tienia

The price is ￥13,322

￥13,322

￥15,545 total

includes taxes & fees

Oct 25 - Oct 26

Spark by Hilton Florence North I-95, SC

A spacious lobby with a checkered floor, a reception desk, and a chandelier.

A two-story building with a brick facade, a flat roof, and a covered entrance area.

A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.

A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.

3. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2.0 star property

Florence

8.6 out of 10, Excellent, (2,743 reviews)

8.6/10

Excellent

(2,743 reviews)

"Very nice place to stay"

"Very nice place to stay"

United States

HOMERO

The price is ￥10,200

￥10,200

￥11,425 total

includes taxes & fees

Oct 18 - Oct 19

Howard Johnson by Wyndham Florence

A hotel lobby with a reception desk, seating area, and a television screen.

A hotel room with a bed, a sofa, an ottoman, and a lamp.

A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.

A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.

4. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 star property

Florence

9.0 out of 10, Wonderful, (1,367 reviews)

9.0/10

Wonderful

(1,367 reviews)

"Breakfast was excellent. Room was clean and quiet."

"Breakfast was excellent. Room was clean and quiet."

United States

Mila

The price is ￥16,013

￥16,013

￥17,935 total

includes taxes & fees

Nov 1 - Nov 2

Comfort Inn & Suites Florence Center Area

A hotel room with a desk, chair, bed, and a yellow sofa.

A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.

A hotel dining area with wooden tables and chairs, a fireplace, and a television.

A swimming pool with lounge chairs and a building with balconies.

5. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 star property

Florence

8.4 out of 10, Very good, (387 reviews)

8.4/10

Very good

(387 reviews)

"Nice spot for an overnight!"

"Nice spot for an overnight!"

United States

Sharhonda

The price is ￥13,927

￥13,927

￥15,597 total

includes taxes & fees

Oct 18 - Oct 19

Quality Inn & Suites Florence Civic Center

An outdoor patio area with tables and chairs, a brick wall, and a glass door leading to the interior.

A spacious lobby with a grand staircase, plush seating, and a modern kitchen area.

A spacious living room with hardwood flooring, a staircase, and a large window.

A spacious bar area with a wooden floor, multiple bar stools, and a variety of bottles on shelves.

6. The Inn at the Crossroads

The Inn at the Crossroads

2.0 star property

Lake City

9.4 out of 10, Exceptional, (999 reviews)

9.4/10

Exceptional

(999 reviews)

"Great stay!!"

"Great stay!!"

United States

Paige

The price is ￥16,060

￥16,060

￥17,987 total

includes taxes & fees

Nov 10 - Nov 11

The Inn at the Crossroads

A hotel room with two beds, a wooden headboard, a nightstand, and three sunset paintings on the wall.

A lobby with a reception desk, seating area, and artwork on the walls.

A modern kitchen with a central island, a dining area with chairs, a large window with a view of palm trees, and a flat-screen TV mounted on the wall.

A Days Inn hotel with a modern design, featuring a parking lot and well-maintained landscaping.

7. Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 star property

Florence

7.2 out of 10, Good, (1,006 reviews)

7.2/10

Good

(1,006 reviews)

"Clean and easy access to restaurants"

"Clean and easy access to restaurants"

United States

Jefferson

The price is ￥10,290

￥10,290

￥11,525 total

includes taxes & fees

Oct 15 - Oct 16

Days Inn by Wyndham Florence Near Civic Center

A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.

Property amenity

An indoor swimming pool with clear blue water, surrounded by green chairs and a tiled floor.

A spacious lobby with a reception desk, a large window display, and a 'market' sign on the wall.

8. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence

3.0 star property

Florence

8.2 out of 10, Very good, (1,000 reviews)

8.2/10

Very good

(1,000 reviews)

"The room Was clean and comfortable and the breakfast was good."

"The room Was clean and comfortable and the breakfast was good."

United States

John

The price is ￥14,629

￥14,629

￥17,324 total

includes taxes & fees

Oct 18 - Oct 19

SpringHill Suites by Marriott Florence

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.

A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.

A modern lounge area with brick walls, large windows, and contemporary furniture.

A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.

9. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3.0 star property

Florence

9.0 out of 10, Wonderful, (1,000 reviews)

9.0/10

Wonderful

(1,000 reviews)

"Convenient hotel, clean and near restaurant options."

"Convenient hotel, clean and near restaurant options."

United States

Ivette

The price is ￥15,831

￥15,831

￥17,732 total

includes taxes & fees

Nov 2 - Nov 3

Hyatt Place Florence Downtown

A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.

A reception area with a modern design, featuring a reception desk, a digital display, and a sign for Holiday Inn Express & Suites.

A coffee station with two coffee machines and a display of coffee pods and cups.

A hotel pool area with two pools, a lifeguard stand, and a towel service station.

10. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

2.5 star property

Florence

9.0 out of 10, Wonderful, (1,002 reviews)

9.0/10

Wonderful

(1,002 reviews)

"Wonderful hotel and in a great location!"

"Wonderful hotel and in a great location!"

United States

Leigh

The price is ￥18,001

￥18,001

￥20,161 total

includes taxes & fees

Oct 18 - Oct 19

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.

A hotel room with two beds, a desk, a TV, and a window with patterned curtains.

A hotel lobby with a reception desk, seating area, and a welcome mat.

11. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

2.5 star property

Florence

9.0 out of 10, Wonderful, (979 reviews)

9.0/10

Wonderful

(979 reviews)

"We loved our stay at the Hampton Inn. The room had plenty of space and was clean. The staff was friendly and they had a lot of options at breakfast. We would definitely stay there again."

"We loved our stay at the Hampton Inn. The room had plenty of space and was clean. The staff was friendly and they had a lot of options at breakfast. We would definitely stay there again."

United States

Ryan

The price is ￥17,985

￥17,985

￥20,143 total

includes taxes & fees

Oct 18 - Oct 19

Hampton Inn & Suites Florence Center

A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.

A hotel room with a sofa, a dining table, a coffee maker, a TV, and artwork on the wall.

An outdoor kitchen area with a grill, a pool, and a covered seating area.

A hotel room with a bed, a desk, a TV, a refrigerator, and a painting on the wall.

12. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG

3.0 star property

Florence

9.4 out of 10, Exceptional, (1,002 reviews)

9.4/10

Exceptional

(1,002 reviews)

"Enjoyed our stay."

"Enjoyed our stay."

United States

Tishia

The price is ￥21,372

￥21,372

￥23,935 total

includes taxes & fees

Nov 1 - Nov 2

Staybridge Suites Florence - Civic Center by IHG

A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.

A modern lounge area with a sofa, armchairs, and small tables.

A self-service beverage station with refrigerated and non-refrigerated drink options, snack shelves, and a sign indicating the location.

13. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

3.0 star property

Florence

9.0 out of 10, Wonderful, (912 reviews)

9.0/10

Wonderful

(912 reviews)

"The staff was amazing!!! The rooms are impeccable the kitchen is excellent!!! I would love to stay here every time"

"The staff was amazing!!! The rooms are impeccable the kitchen is excellent!!! I would love to stay here every time"

United States

Crystal

The price is ￥17,359

￥17,359

￥19,444 total

includes taxes & fees

Nov 2 - Nov 3

TownePlace Suites by Marriott Florence

A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.

A Comfort Suites hotel with a modern design, featuring a prominent entrance with columns, a covered walkway, and a clear blue sky.

An outdoor patio area with tables and chairs, a barbecue grill, and a large window overlooking a fenced area.

A hotel room with a bed, a blue sofa, a brown ottoman, a black office chair, a desk, a lamp, and three framed pictures on the wall.

14. Comfort Suites Florence I-95

Comfort Suites Florence I-95

2.5 star property

Florence

8.2 out of 10, Very good, (1,001 reviews)

8.2/10

Very good

(1,001 reviews)

"Very convenient to highway"

"Very convenient to highway"

United States

Denise

The price is ￥14,241

￥14,241

￥17,522 total

includes taxes & fees

Oct 18 - Oct 19

Comfort Suites Florence I-95

A swimming pool with lounge chairs and a building with a sign reading "BAYMONT".

A modern living room with a sectional sofa, a coffee table, and a flat-screen TV mounted on the wall.

A hotel room with a large bed, a desk, a chair, a TV, and a painting of a waterfall on the wall.

A motel with a covered parking area, a gas station sign, and a row of rooms with balconies.

15. Super 8 by Wyndham Florence

Super 8 by Wyndham Florence

2.0 star property

Florence

7.2 out of 10, Good, (1,000 reviews)

7.2/10

Good

(1,000 reviews)

"Great and affordable stay"

"Great and affordable stay"

United States

Shawn

The price is ￥8,590

￥8,590

￥9,621 total

includes taxes & fees

Oct 18 - Oct 19

Super 8 by Wyndham Florence

A hotel room with a bed, bedside table with a phone, a desk with a chair, a TV mounted on the wall, and a window with curtains.

A conference room with a wooden table, chairs, a TV, and a computer on a shelf.

A multi-story hotel with a prominent entrance marked '1912'.

A modern kitchen with dark wood cabinets, stainless steel appliances, and a large juice dispenser.

16. Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence

2.0 star property

Florence

7.0 out of 10, Good, (1,002 reviews)

7.0/10

Good

(1,002 reviews)

"I enjoyed my stays"

"I enjoyed my stays"

United States

Carletta

The price is ￥8,865

￥8,865

￥9,929 total

includes taxes & fees

Oct 26 - Oct 27

Microtel Inn & Suites by Wyndham Florence

A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.

A modern breakfast area with a buffet setup, including a microwave, coffee maker, and various food items.

A hotel room with a bed, a sofa, a desk, and a TV.

A hotel room with a bed, sofa, TV, and a desk.

17. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3.0 star property

Florence

7.8 out of 10, Good, (1,484 reviews)

7.8/10

Good

(1,484 reviews)

"Very convenient location Friendly and helpful staff"

"Very convenient location Friendly and helpful staff"

United States

Heather

The price is ￥13,500

￥13,500

￥15,122 total

includes taxes & fees

Oct 18 - Oct 19

La Quinta Inn & Suites by Wyndham Florence

A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.

A large, two-story building with a central entrance flanked by columns, labeled "DIR FRANK B. LEE NURSING BUILDING."

An outdoor patio area with brick walls, a fire pit, and outdoor seating.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.

18. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

2.5 star property

Florence

8.6 out of 10, Excellent, (1,000 reviews)

8.6/10

Excellent

(1,000 reviews)

"Good location- very good free breakfast"

"Good location- very good free breakfast"

United States

Christopher

The price is ￥19,264

￥19,264

￥23,138 total

includes taxes & fees

Oct 18 - Oct 19

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

A restaurant with brick walls, framed awards, and a bar area.

A spacious kitchen with a dining area, a living room with a fireplace, and a cozy seating arrangement.

An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.

A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.

19. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton

3.0 star property

Florence

8.8 out of 10, Excellent, (658 reviews)

8.8/10

Excellent

(658 reviews)

"Beautifully located hotel with plenty of restaurants and bars around. The room was super large and well taken care. Definitely recommended"

"Beautifully located hotel with plenty of restaurants and bars around. The room was super large and well taken care. Definitely recommended"

United States

Ankh

The price is ￥18,174

￥18,174

￥20,356 total

includes taxes & fees

Nov 1 - Nov 2

Hotel Florence, Tapestry Collection by Hilton

An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.

A modern hotel with a prominent 'TRU by Hilton' sign, a well-lit entrance, and a landscaped front yard.

A modern lounge area with seating, tables, and a pool table.

20. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95

2.5 star property

Florence

8.6 out of 10, Excellent, (1,003 reviews)

8.6/10

Excellent

(1,003 reviews)

"Excellent quick stay while traveling. Very clean room and easy check in and out."

"Excellent quick stay while traveling. Very clean room and easy check in and out."

United States

Tiffany

The price is ￥15,979

￥15,979

￥18,836 total

includes taxes & fees

Oct 21 - Oct 22

Tru by Hilton Florence I-95

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Florence County Hotel Reviews

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

8/10 Good

"Good"

April 1-night trip

Posted 14 hours ago

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

8/10 Good

"The air conditioner was not as cold as the last time we were there but overall good place"

Coy 1-night trip

Posted 15 hours ago

Howard Johnson by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

10/10 Excellent

"Room was very clean and well presented. Bathroom was large and well stocked with extra tissue, towels, and shower had complementary shampoo, body wash and conditioner. Room had mini fridge and microwave. Large screen tv with all needed channels plus HBO. Breakfast buffet was excellent as well as all staff present. A very big bonus for us is the place is PET FRIENDLY!!! We will be back!"

Lester 1-night trip

Posted 2 days ago

La Quinta Inn & Suites by Wyndham Florence

Super 8 by Wyndham Florence

Super 8 by Wyndham Florence

10/10 Excellent

"Room was clean. Bed was comfortable. This was a stop for the night, but we were happy with it, especially for the reasonable price."

Nancy 1-night trip

Posted 2 days ago

Super 8 by Wyndham Florence

Aloft by Marriott Florence

Aloft by Marriott Florence

8/10 Good

"Room was clean. Staff was helpful."

Brandy 1-night trip

Posted 2 days ago

Aloft by Marriott Florence

Comfort Suites Florence I-95

Comfort Suites Florence I-95

10/10 Excellent

"Everything was excellent- the staff, the rooms, the parking, you name it. Very satisfied"

Mary 1-night trip

Posted 2 days ago

Comfort Suites Florence I-95

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

10/10 Excellent

"Overview... it was Excellent. Clean, very comfortable spacious and convenient to restaurants. Staff was helpful and nice. Updates were very nice.Would definitely stay again."

Barbara 1-night trip

Posted 2 days ago

Spark by Hilton Florence North I-95, SC

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

8/10 Good

"Nothing to say"

jun 1-night trip

Posted 2 days ago

Comfort Inn & Suites Florence Center Area

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