A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Apartments in Defiance for Rent

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Check prices for these dates

In two weeks
Nov 6 - Nov 8
In two months
Dec 18 - Dec 20
In three months
Jan 15 - Jan 17
In four months
Feb 12 - Feb 14

Our top choices for Defiance apartments

A hotel pool area with a rectangular pool, lounge chairs, and a wooden bench.

1. Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
4.0 out of 10, (1 review)
"Property was dirty, kitchen hadn’t been cleaned. Microwave had food spilled all over inside. Place felt grimy."
United States
Jenny D.
The price is ￥20,160
￥26,944 total
includes taxes & fees
Oct 25 - Oct 26
Great for Business Travelers! Pool + Gym
A room with a dark wooden wall, a brown leather sofa, a white door, and a patterned wall.

2. Stylish1BRStudioCleanQuietandCozy

Stylish1BRStudioCleanQuietandCozy
Saint Charles
10.0 out of 10, Exceptional, (3 reviews)
"Room was very clean with little to no issues at all. Host was super easy to work with and get information from. This spot is within 15-20minutes OR LESS to anything you’d need to do in the ofallon and surrounding areas. I’d book it again if I needed to."
United States
Mike S.
The price is ￥13,296
￥41,639 total
includes taxes & fees
Oct 23 - Oct 24
Stylish1BRStudioCleanQuietandCozy
A front door with a sign for '2nd St Loft' and a 'Self Check In' option.

3. 2nd Street Loft - Riverview

2nd Street Loft - Riverview
Washington
10.0 out of 10, Exceptional, (20 reviews)
"Everything was great room was very clean"
United States
Chance W.
The price is ￥13,568
￥27,623 total
includes taxes & fees
Oct 26 - Oct 27
2nd Street Loft - Riverview
A set of stone steps leading to a garage with a car parked inside.

4. Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues

Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues
Ballwin
7.8 out of 10, Good, (24 reviews)
"Rooms were clean and everything we needed for our stay."
United States
Keith K.
The price is ￥10,676
￥23,279 total
includes taxes & fees
Nov 1 - Nov 2
Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues
A bedroom with a bed, a dresser, a mirror, a ceiling fan, and a door leading to another room.

5. Enjoyable 2-bedroom apartment at St. Peters; Near STL

Enjoyable 2-bedroom apartment at St. Peters; Near STL
St. Peters
The price is ￥17,094
￥44,799 total
includes taxes & fees
Oct 26 - Oct 27
Enjoyable 2-bedroom apartment at St. Peters; Near STL
A two-story building with a balcony, a staircase, and a gated entrance.

6. 2nd Street -Deck Suite (back entrance)

2nd Street -Deck Suite (back entrance)
Washington
10.0 out of 10, Exceptional, (11 reviews)
"The property was clean and comfortable and everything you may need is there, walking distance was very close to everything in the area. Communication with the host was easy and quick responses, overall it was a great place to stay!"
United States
Melinda
The price is ￥14,255
￥29,307 total
includes taxes & fees
Nov 1 - Nov 2
2nd Street -Deck Suite (back entrance)
A living room with a white sofa, two armchairs, a wooden coffee table, and a side table with a plant.

7. The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail

The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail
Marthasville
8.4 out of 10, Very good, (5 reviews)
"This was the perfect place for my friends and I to stay in Marthasville. Lots of space and amenities. We did not use the complimentary breakfast, but is a great addition. Would recommend to anyone staying in the area. "
United States
Adam K.
The price is ￥39,527
￥76,619 total
includes taxes & fees
Nov 1 - Nov 2
The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail
A modern kitchen with white cabinets, a black refrigerator, a stainless steel microwave, and a black oven. There are four blue bowls on a wooden table with a woven placemat.

8. Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi

Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi
Moscow Mills
10.0 out of 10, Exceptional, (14 reviews)
"Great place, nice neighborhood. "
United States
Julie L.
The price is ￥19,835
￥42,611 total
includes taxes & fees
Nov 1 - Nov 2
Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi
A hotel room with a bed, a desk, a chair, a lamp, and a telephone.

9. 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed

1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed
Westport
9.4 out of 10, Exceptional, (43 reviews)
"Great spot!"
United States
Anonymous traveler
The price is ￥9,394
￥10,897 total
includes taxes & fees
Oct 25 - Oct 26
1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed
A neatly made bed with a stack of folded towels, a bedside lamp, and a ceiling fan in a room with a large window and a wall-mounted artwork.

10. Walk to Main | Pet-Friendly Yard & Workspace

Walk to Main | Pet-Friendly Yard & Workspace
St. Charles Historic District
10.0 out of 10, Exceptional, (12 reviews)
"Very close to downtown St. Charles and the Kati Trail. The home is cute and bed is comfortable. Easy check in process and fenced in back yard was nice to have."
United States
Jessica S.
The price is ￥18,107
￥41,040 total
includes taxes & fees
Oct 25 - Oct 26
Walk to Main | Pet-Friendly Yard & Workspace
Free breakfast available on-site.

11. Studio | Lovely Suite Close to Edward Jones!

Studio | Lovely Suite Close to Edward Jones!
Westport
Studio | Lovely Suite Close to Edward Jones!
A brick building with numbered doors, a covered walkway, and a visible handicap accessibility sign.

12. Foundry Flat | Main Street & Free Parking

Foundry Flat | Main Street & Free Parking
St. Charles Historic District
10.0 out of 10, Exceptional, (1 review)
"Everything was exactly as described. St. Charles is an awesome place!"
United States
Michael
The price is ￥17,462
￥47,590 total
includes taxes & fees
Nov 22 - Nov 23
Foundry Flat | Main Street & Free Parking
A hallway with a door, two potted plants, a doormat, and a view of a brick building through large windows.

13. Dog-Friendly 2BR | Walk to Main Street

Dog-Friendly 2BR | Walk to Main Street
Saint Charles
8.0 out of 10, Very good, (5 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
The price is ￥15,727
￥43,934 total
includes taxes & fees
Oct 25 - Oct 26
Dog-Friendly 2BR | Walk to Main Street
A modern kitchen with white cabinets, a built-in microwave, a stove, and a window providing natural light.

14. Pet-Friendly Duplex | Historic Main

Pet-Friendly Duplex | Historic Main
St. Charles Historic District
10.0 out of 10, Exceptional, (26 reviews)
"Great location"
United States
todd p.
The price is ￥19,146
￥42,727 total
includes taxes & fees
Oct 29 - Oct 30
Pet-Friendly Duplex | Historic Main
A modern kitchen with stainless steel appliances, white cabinetry, and a brick accent wall.

15. Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (39 reviews)
"Lovely place to stay!"
United States
Margaret A.
The price is ￥19,658
￥55,193 total
includes taxes & fees
Oct 26 - Oct 27
Historic Main St. Customs House Upstairs Apartment
A row of multi-story buildings with commercial storefronts, including a cafe and a restaurant.

16. Historic Main Street Studio | Dog-Friendly

Historic Main Street Studio | Dog-Friendly
St. Charles Historic District
9.2 out of 10, Wonderful, (40 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
The price is ￥14,520
￥33,466 total
includes taxes & fees
Oct 25 - Oct 26
Historic Main Street Studio | Dog-Friendly
A spacious living area with a wooden floor, a dining table with chairs, a flat-screen TV mounted on the wall, and a kitchen area with modern appliances.

17. The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (195 reviews)
"Such an awesome place! Super. Lean and great location. Loved our stay!"
United States
Jill C.
The price is ￥21,986
￥43,847 total
includes taxes & fees
Oct 25 - Oct 26
The Lofts of North Main Street
A cozy living room with a sofa, chairs, a coffee table, and a clock.

18. 1st Capitol Mansion - Suite 401

1st Capitol Mansion - Suite 401
St. Charles Historic District
7.4 out of 10, Good, (9 reviews)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
The price is ￥15,659
￥39,046 total
includes taxes & fees
Nov 22 - Nov 23
1st Capitol Mansion - Suite 401
A modern living room with a sectional sofa, a wooden coffee table, and a large window with blinds.

19. Walk to Main St | Pet-Friendly Apt

Walk to Main St | Pet-Friendly Apt
St. Charles Historic District
8.8 out of 10, Excellent, (18 reviews)
"Property was as advertised. Perfect for my needs, clean, quiet and convenient. Loved Historic St. Charles. Would recommend anytime! Thank you! "
United States
Brian B.
The price is ￥17,094
￥46,143 total
includes taxes & fees
Nov 3 - Nov 4
Walk to Main St | Pet-Friendly Apt
A staircase with white railings and a ceiling fan.

20. Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (71 reviews)
"This was a prime spot for downtown activities! Near everything and not far from STL. Would absolutely stay here again!"
United States
Rebecca F.
The price is ￥21,986
￥44,163 total
includes taxes & fees
Oct 27 - Oct 28
Amazing Renovated Historic Loft on Main Street
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent
"Good breakfast and hot tub was nice."
michael 1-night trip
Posted 2 hours ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Find out more about Defiance

Defiance Apartments information

Number of reviews
532
Accommodation
114 Apartments
Lowest Price
￥10,897
Highest Price
￥76,619

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your stay.
Why choose an apartment versus a traditional hotel?
Often more spacious than a traditional hotel room, an apartment includes a kitchen for convenient home-cooked meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want something in a quieter part of town.
What's a favorite apartment for a stay in Defiance?
Here are some of the top apartments in the area: 2 Queen Beds | Non-Smoking, Kitchen: Situated in Maryland Heights, 18.7 mi/30.1 km from the heart of Defiance. Includes free WiFi and Smart TVs. 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed: Located 18.7 mi/30.1 km away in Maryland Heights. Free WiFi and Smart TVs are included. The Lofts of North Main Street: Located in St. Charles, 19.2 mi/30.8 km away. Includes free WiFi, sofa beds, and Smart TVs. Access to onsite laundry facilities is available on site. Driftwood Den | Boho 2BR | Dog-Friendly: It's located in St. Charles, 19 mi/30.6 km from Defiance. Includes free WiFi.
How many apartments will I be able to find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather during my trip to Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you're planning an extended stay in Defiance. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Yellow Farmhouse Winery and Chandler Hill Vineyards are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can save you time when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. You can also search for flights into St. Louis Lambert Intl. Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, you may want a rental car for your journey.