Find Business Hotels in Central San Diego, CA
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Central San Diego Business Hotels
Top Central San Diego Business Hotels
Our top choices for Central San Diego business-friendly hotels

Ayres Lodge Alpine
Ayres Lodge Alpine
9.2 out of 10, Wonderful, (1019)
The price is ¥14,931
¥16,155 total
includes taxes & fees
Sep 28 - Sep 29

Sycuan Casino Resort
Sycuan Casino Resort
9.2 out of 10, Wonderful, (1549)
The price is ¥15,180
¥18,484 total
includes taxes & fees
Oct 1 - Oct 2

Ayres Hotel San Diego South - Chula Vista
Ayres Hotel San Diego South - Chula Vista
9.8 out of 10, Exceptional, (1097)
The price is ¥20,132
¥22,184 total
includes taxes & fees
Oct 8 - Oct 9

Legacy Resort Hotel & Spa
Legacy Resort Hotel & Spa
9.2 out of 10, Wonderful, (2891)
The price is ¥23,137
¥26,595 total
includes taxes & fees
Sep 28 - Sep 29

Lafayette Hotel & Club
Lafayette Hotel & Club
9.2 out of 10, Wonderful, (1166)
The price is ¥33,360
¥38,281 total
includes taxes & fees
Sep 29 - Sep 30

Hilton Garden Inn San Diego Mission Valley Stadium
Hilton Garden Inn San Diego Mission Valley Stadium
8.0 out of 10, Very Good, (1015)
The price is ¥18,035
¥20,731 total
includes taxes & fees
Sep 29 - Sep 30

Best Western Seven Seas
Best Western Seven Seas
7.8 out of 10, Good, (2967)
The price is ¥12,480
¥14,346 total
includes taxes & fees
Sep 28 - Sep 29

Ramada Suites by Wyndham San Diego/Hotel Circle Area
Ramada Suites by Wyndham San Diego/Hotel Circle Area
6.2 out of 10, (1005)
The price is ¥9,853
¥11,326 total
includes taxes & fees
Sep 28 - Sep 29
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Central San Diego Hotel Reviews

California Suites Hotel
10/10 Excellent
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Top neighborhoods for Business Hotels
Find More Hotels near Central San Diego
More Hotel Options in Central San Diego
- Adults Only Resorts & Hotels in Central San Diego
- Adventure Hotels in Central San Diego
- Beach Hotels in Central San Diego
- Boutique Hotels in Central San Diego
- Casinos in Central San Diego
- Cheap Hotels in Central San Diego
- Family Hotels in Central San Diego
- Gay friendly Hotels in Central San Diego
- Golf Hotels in Central San Diego
- Green Hotels in Central San Diego
- Historic Hotels in Central San Diego
- Hotel Wedding Venues in Central San Diego
- Hotel with a Concierge in Central San Diego
- Hotels with Bars in Central San Diego
- Hotels with Early Check-in in Central San Diego
- Hotels with Free Parking in Central San Diego
- Hotels with Hot Tubs in Central San Diego
- Hotels with WiFi in Central San Diego
- Hotels with a Pool in Central San Diego
- Hotels with an Indoor Pool in Central San Diego
- Hotels with smoking rooms in Central San Diego
- Luxury Hotels in Central San Diego
- Pet-friendly Hotels in Central San Diego
- Resorts & Hotels with Spas in Central San Diego
- Romantic Hotels in Central San Diego
- Shopping Hotels in Central San Diego
- Ski Hotels in Central San Diego
More Accommodation Types in Central San Diego
- Vacation Homes in San Diego
- Apartments in San Diego
- Condo Rentals in San Diego
- Cottages in San Diego
- Villas in San Diego
- Guest Houses in San Diego
- Aparthotels in San Diego
- Resorts in San Diego
- Motels in San Diego
- Hostels in San Diego
- B&B in San Diego
- Houseboats in San Diego
- Inns in San Diego
- Cabin Rentals in San Diego
- RV Parks in San Diego
- Condo Resorts in San Diego
- Residences in San Diego
Hotels near popular San Diego Attractions
- Hotels near San Diego Zoo
- Hotels near Balboa Park
- Hotels near San Diego State University
- Hotels near Hotel Circle
- Hotels near University of San Diego
- Hotels near Old Town San Diego State Park
- Hotels near Marine Corps Air Station Miramar
- Hotels near Fashion Valley Mall
- Hotels near Snapdragon Stadium
- Hotels near Westfield UTC
Central San Diego Hotels by Star Rating
Explore more hotels
- Lafayette Hotel & Club
- Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area
- San Diego Marriott Mission Valley
- Sheraton Mission Valley San Diego Hotel
- DoubleTree by Hilton San Diego - Hotel Circle
- Hilton Garden Inn San Diego Old Town/SeaWorld Area
- The Atwood Hotel San Diego - SeaWorld/Zoo
- Embassy Suites by Hilton San Diego La Jolla
- Courtyard by Marriott San Diego Mission Valley/Hotel Circle
- Ramada Suites by Wyndham San Diego/Hotel Circle Area
- Best Western Seven Seas
- Fairfield Inn & Suites San Diego Old Town
- Balboa Park Hotel
- Super 8 by Wyndham San Diego Hotel Circle
- Uptown Inn by Vantaggio - Limited Service Apart-Hotel
- Hilton Garden Inn San Diego Mission Valley Stadium
- Courtyard by Marriott San Diego Sorrento Valley
- Best Western Plus Hacienda Hotel Old Town
More ways to book
Expedia's Latest Trends
Hotels
- Pan Pacific Serviced Suites Orchard, Singapore
- Hotels near Hiroshima Station
- Hotels near Aiko-Ishida Station
- Hotel WA HAKATA
- Hyatt Regency Chennai
- Cheap Hotels in LAX Area
- Tokyo Toranomon Tokyu REI Hotel
- Yamadaya Ryokan
- Hotels in Shikine-jima
- Hotel Rotterdam Huis Ten Bosch
- Hotels in LAX Area
- Natural Hot Spring Midosuji Hotel
- ANA Crowne Plaza Toyama by IHG
- Hotels near Gotanda Station
- Cabin Rentals Japan
- Paris Marriott Rive Gauche Hotel & Conference Center
- Hotel Monterey Sendai
- Mercure Yokosuka
Flights
- Flights from Narita (NRT) to Higashine (GAJ)
- Flights from San Francisco (SFO) to Cancun (CUN)
- Flights from Kunisaki (OIT) to Makinohara (FSZ)
- Flights from Fukuoka (FUK) to Tuban (DPS)
- Flights from Tokyo (HND) to Izumo (IZO)
- Flights from Natori (SDJ) to Hiroshima (HIJ)
- Flights from Chek Lap Kok (HKG) to London (LHR)