Find Business Hotels in Central San Diego, CA

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Central San Diego Business Hotels

Top Central San Diego Business Hotels

DoubleTree by Hilton Hotel San Diego - Mission Valley

4.0 star property
Mission Valley
8.4 out of 10, Very Good, (1337)
"Nice hotel"
United States
Ken
The price is ¥17,126
¥19,685 total
includes taxes & fees
Nov 26 - Nov 27
DoubleTree by Hilton Hotel San Diego - Mission Valley

Hilton Garden Inn San Diego Mission Valley Stadium

3.0 star property
Kearny Mesa
8.0 out of 10, Very Good, (1003)
"The staff were wonderful"
United States
Julie
The price is ¥15,367
¥17,663 total
includes taxes & fees
Dec 14 - Dec 15
Hilton Garden Inn San Diego Mission Valley Stadium

Legacy Resort Hotel & Spa

4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2924)
"Great hotel"
United States
Michael
The price is ¥26,059
¥29,954 total
includes taxes & fees
Dec 4 - Dec 5
Legacy Resort Hotel & Spa

Best Western Plus Hacienda Hotel Old Town

3.0 star property
Old Town San Diego
8.4 out of 10, Very Good, (1823)
"Very clean staff is very friendly and kind. Great place to stay "
United States
Rhonda
The price is ¥19,274
¥22,155 total
includes taxes & fees
Nov 17 - Nov 18
Best Western Plus Hacienda Hotel Old Town

San Diego Marriott La Jolla

4.0 star property
University City
8.6 out of 10, Excellent, (2138)
"Great stay! This will be the hotel we stay when we come back."
United States
Scott
The price is ¥23,876
¥27,475 total
includes taxes & fees
Nov 14 - Nov 15
San Diego Marriott La Jolla

Handlery Hotel

3.5 star property
Mission Valley
8.2 out of 10, Very Good, (2195)
"Great rooms bed was comfy room service kept the room nice when we are away. The pool was amazing family enjoyed the hot tub "
United States
Nick
Handlery Hotel

Holiday Inn Express & Suites San Diego - Mission Valley by IHG

2.5 star property
Mission Valley
8.8 out of 10, Excellent, (1004)
"Ver clean room , excellent services from staff"
United States
Carmela
The price is ¥18,487
¥21,712 total
includes taxes & fees
Dec 7 - Dec 8
Holiday Inn Express & Suites San Diego - Mission Valley by IHG

Hilton San Diego Mission Valley

4.0 star property
Mission Valley
8.0 out of 10, Very Good, (2162)
"Very good place to stay at"
Canada
Shan
The price is ¥17,560
¥20,183 total
includes taxes & fees
Nov 25 - Nov 26
Hilton San Diego Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 star property
Mission Valley
8.8 out of 10, Excellent, (1231)
"Great location "
United States
Martha E
The price is ¥15,966
¥18,352 total
includes taxes & fees
Dec 1 - Dec 2
Hampton Inn San Diego/Mission Valley

Best Western San Diego/Miramar Hotel

2.5 star property
Miramar
7.8 out of 10, Good, (1132)
"Comfy bed, huge tv, great breakfast!"
United States
Grace
The price is ¥13,117
¥15,078 total
includes taxes & fees
Nov 30 - Dec 1
Best Western San Diego/Miramar Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Central San Diego Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

Why book your business-friendly hotel in Central San Diego with Expedia?
Expedia will help you find the ideal business-friendly hotel for your upcoming work trip. From meeting rooms and conference spaces to on-site restaurants and more, our accommodations have all you'll need to settle that big contract.
How can I find cheap business-friendly hotels in Central San Diego?
Click on the "business friendly" filter, located under the "traveler experience" heading, to find cheap business-friendly hotels in Central San Diego. Then fine-tune your search by your nightly budget. Looking for properties away from the center can also help you save.