Find Business Hotels in Cape Cod, MA

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Check availability on Cape Cod Business Hotels

Our top choices for Cape Cod business-friendly hotels

Iris Hotel Cape Cod

Iris Hotel Cape Cod
3.0 star property
Falmouth
8.4 out of 10, Very Good, (155)
"great bedroom "
United States
Jessica
The price is ¥15,256
¥17,462 total
includes taxes & fees
Dec 22 - Dec 23
Iris Hotel Cape Cod

Cape Cod Hotel

Cape Cod Hotel
2.5 star property
Hyannis
7.4 out of 10, Good, (1000)
"Great stay"
United States
Vanuze
The price is ¥15,256
¥19,240 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Cape Cod Hotel

Aiden by Best Western Cape Cod - West Yarmouth

Aiden by Best Western Cape Cod - West Yarmouth
3.0 star property
West Yarmouth
8.0 out of 10, Very Good, (1000)
"Nice place and good options for breakfast "
United States
Jennifer
The price is ¥13,094
¥14,986 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Aiden by Best Western Cape Cod - West Yarmouth

Hyannis Harbor Hotel

Hyannis Harbor Hotel
3.5 star property
Hyannis
8.0 out of 10, Very Good, (1000)
"Amazing place "
United States
Mounir
The price is ¥18,470
¥27,422 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Hyannis Harbor Hotel

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
Hyannis
8.0 out of 10, Very Good, (1004)
"Nice hotel had a perfect stay"
United States
David
The price is ¥15,264
¥17,470 total
includes taxes & fees
Dec 25 - Dec 26
Comfort Inn Hyannis - Cape Cod

Falmouth Inn

Falmouth Inn
2.0 star property
Falmouth
8.0 out of 10, Very Good, (1000)
"Clean room, good shower and helpful staff."
United States
Mark
The price is ¥16,103
¥21,541 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Falmouth Inn

All Seasons Resort, Trademark Collection by Wyndham

All Seasons Resort, Trademark Collection by Wyndham
3.0 star property
Bass River
8.4 out of 10, Very Good, (306)
"My room was very clean. The staff were friendly."
United States
Shanique
The price is ¥13,304
¥17,362 total
includes taxes & fees
Dec 21 - Dec 22
All Seasons Resort, Trademark Collection by Wyndham

Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod
4.0 star property
Hyannis
8.8 out of 10, Excellent, (415)
"The entire place was spotless and rooom beet pleasant. Staff was super friendly and the Landshark Bar was excellent. Highly recommend a stay here ! "
United States
Stephen
The price is ¥21,784
¥33,837 total
includes taxes & fees
Dec 21 - Dec 22
Margaritaville Resort Cape Cod

Sea Crest Beach Resort

Sea Crest Beach Resort
3.5 star property
North Falmouth
8.0 out of 10, Very Good, (247)
"Clean room. Good spot for family weekend getaway "
United States
ALAIN BERNARD
The price is ¥19,750
¥31,504 total
includes taxes & fees
Dec 28 - Dec 29
Sea Crest Beach Resort

Courtyard Resort

Courtyard Resort
2.0 star property
Hyannis
8.2 out of 10, Very Good, (45)
"Clean and inexpensive"
United States
Robert
The price is ¥16,951
¥19,400 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Courtyard Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Cape Cod Hotel Reviews

Frequently asked questions

How much do business-friendly hotels in Cape Cod cost?
Rates for business hotels in Cape Cod range between and per night. Whatever your budget, Expedia can help you locate the ideal place for a smooth work trip. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Cape Cod?
Cape Cod offers multiple business-friendly hotels with a total average guest review rating of . Working on the road in Hyannis? Sesuit Harbor House is a 3-stars stay that's highly recommended by corporate travelers and includes pool sun loungers and a firepit. Another suitable option for a business trip is The Escape Inn. Also located in Hyannis, it has a 2.5-stars rating and amenities such as a garden and pool sun loungers.
How many business-friendly hotels are there in Cape Cod?
Cape Cod has business-friendly hotels to choose from. Whether you're catching up with clients or simply working remotely, these stays come with everything you need to be productive.
What are the best cheap business-friendly hotels in Cape Cod?
When work is taking you on the road in Cape Cod, Expedia will help you find the ideal business-friendly hotel. The Escape Inn is a top budget option in Hyannis. A terrace and a garden are some of its many amenities. Looking for affordable properties in West Yarmouth? The Escape Inn is the first choice for many corporate guests. It has conveniences that make it easy to both work and feel at home, such as pool sun loungers and a garden. Business-friendly hotels in Cape Cod start at only per night. Mix business with leisure by visiting a few fabulously free attractions on your work-related trip in Cape Cod. West Dennis Beach in Hyannis is popular. If you're planning a trip to West Yarmouth, you won't have to spend a cent when visiting West Dennis Beach. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the top business-friendly motels in Cape Cod?
If your Cape Cod business trip includes Wellfleet, choose Eagle Wing Inn - Cape Cod. Around 14 kilometers south of the downtown area and offering a swimming pool and a garden, it's a top choice for corporate guests. Alternatively, get down to work from Endless Coast, A Boutique Hotel. A firepit and a marina are among the conveniences at this stay, located around 2 kilometers southeast of central Wellfleet.You'll have plenty of things to see during your spare time in Hyannis. West Dennis Beach and Cape Codder Water Park should be on your sightseeing checklist.
Are there any family-friendly hotels in Cape Cod that are also business friendly?
You'll discover some wonderful family-friendly hotels that are also business friendly in Cape Cod. If you're on your way to Hyannis, look up Sesuit Harbor House. It offers useful amenities such as a children's pool and a playground and has a 3-stars rating. Another option to consider is Riverview Resort By Vri Americas. This 3-stars stay in Hyannis is ideal for both leisure and business travelers and offers a playground, WiFi and lots more. When you're done with work, get out and see Hyannis with the kids. Top family-friendly attractions include West Dennis Beach and Cape Codder Water Park.
Why book your business-friendly hotel in Cape Cod with Expedia?
Expedia is here to help you find a fantastic business-friendly hotel for your upcoming work trip. From meeting rooms and conference spaces to gyms and spas, our stays come with the conveniences you'll need to settle that big contract.
How can I find cheap business-friendly hotels in Cape Cod?
When work takes you on the road in Cape Cod, our "business friendly" filter will help you find the right hotel. From WiFi to concierge services and conference spaces, they have the amenities you need to get the job done. Another tip? Narrow your search by your budget and preferred star rating to view the most affordable stays.
What is there to do in Cape Cod near my business-friendly hotel?
One of the best travel accessories for your Cape Cod work visit is a good itinerary for when you have some free time! Cape Codder Water Park, Cape Cod Inflatable Park and John F. Kennedy Hyannis Museum are some of the most popular things to do if you're bound for Hyannis. West Yarmouth also has lots of famous attractions, such as Cape Cod Inflatable Park, Seagull Beach and John F. Kennedy Hyannis Museum.

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