A calm river with boats, lush greenery, and a clear blue sky.

Find Luxury Hotels in Big Pine Key, FL

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Check availability on Big Pine Key Luxury Hotels

Tonight
Sep 17 - Sep 18
Tomorrow
Sep 18 - Sep 19
This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

Our top choices for Big Pine Key luxury hotels

1. Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
Marathon
  • Oceanfront luxury in Marathon offers private beach, spa services, 4 pools, and spectacular nightly sunsets.
¥22,939
¥31,687 total
includes taxes & fees
Sep 27 - Sep 28
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

2. Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa
Marathon
  • Indulge in beachfront serenity with 5 outdoor pools, full-service spa, and private balconies overlooking the Florida Keys coast.
¥31,647
¥44,934 total
includes taxes & fees
Sep 21 - Sep 22
Isla Bella Beach Resort & Spa

3. Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club
Marathon
¥27,360
¥38,282 total
includes taxes & fees
Oct 18 - Oct 19
Grassy Flats Resort & Beach Club

4. Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
Marathon
  • Beachfront luxury offers 3 pools, private beach access, and spa treatments blending tranquility with Keys charm.
¥32,663
¥46,784 total
includes taxes & fees
Sep 22 - Sep 23
Tranquility Bay Beachfront Hotel and Resort
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Top Big Pine Key Hotel Reviews

Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Big Pine Key?
Expedia can help you arrange a flight to Marathon, FL (MTH-Florida Keys Marathon) airport or Key West Intl. Airport (EYW) airport, and then you can select from various places to stay that will deliver the luxury you'd like to find. Amenities are important when you plan a trip, so we make it easy to find what you need to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Big Pine Key offers. Big Pine Key has some interesting things to see and do including Florida Keys Beaches and Calusa Beach, so you might want to take in the local sights during your visit.
When can I expect good weather in Big Pine Key?
Planning for the weather is an important factor for making your trip to Big Pine Key a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 84°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Big Pine Key is 36 inches.
What's there to see and do in Big Pine Key?
Experience all that Big Pine Key has to offer when you visit Florida Keys Beaches, Calusa Beach, and Bahia Honda State Park. If you have spare time during your trip, you might want to make a stop at Big Pine Key Flea Market and Cook Island.

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