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Check availability on South San Francisco 5 Star Hotels

Tonight
Apr 22 - Apr 23
Tomorrow
Apr 23 - Apr 24
This weekend
Apr 24 - Apr 26
Next weekend
May 1 - May 3

Our top choices for South San Francisco 5-star hotels

Terrace/patio

Fairmont San Francisco

Fairmont San Francisco
5.0 star property
Downtown San Francisco
9.0 out of 10, Wonderful, (1,512 reviews)
"Great staff; nice restaurants. "
Canada
Robert
The price is ￥47,823
￥63,789 total
includes taxes & fees
May 3 - May 4
Fairmont San Francisco
View from property

Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (1,000 reviews)
"Wonderful stay! We loved it!"
United States
Sara
The price is ￥47,201
￥63,058 total
includes taxes & fees
May 3 - May 4
Palace Hotel, a Luxury Collection Hotel, San Francisco
Bar (on property)

Taj Campton Place

Taj Campton Place
5.0 star property
Union Square
9.2 out of 10, Wonderful, (1,000 reviews)
"The Taj Campton is a welcoming place to stay and we have become repeat visitors. All the things that matter are met: cleanliness, comfort, thoughtfulness, location and friendliness. "
United States
William
The price is ￥26,956
￥37,292 total
includes taxes & fees
Apr 26 - Apr 27
Taj Campton Place
Rooftop terrace

Four Seasons Hotel San Francisco at Embarcadero

Four Seasons Hotel San Francisco at Embarcadero
5.0 star property
Downtown San Francisco
9.6 out of 10, Exceptional, (1,001 reviews)
"Very friendly staff and overall had a great visit"
United States
Michael
The price is ￥69,463
￥81,755 total
includes taxes & fees
May 22 - May 23
Four Seasons Hotel San Francisco at Embarcadero
Breakfast, lunch, dinner served; alfresco dining

1 Hotel San Francisco

1 Hotel San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (535 reviews)
"Great staff & very clean facility "
United States
ARMANDO
The price is ￥65,199
￥85,741 total
includes taxes & fees
Apr 24 - Apr 25
1 Hotel San Francisco
Terrace/patio

Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1,002 reviews)
" Excellent rooms and staff, terrific food, great location "
United States
Roberta
The price is ￥70,653
￥83,155 total
includes taxes & fees
May 21 - May 22
Four Seasons Hotel San Francisco
Terrace/patio

Claremont Resort & Club

Claremont Resort & Club
5.0 star property
Claremont Hills
9.0 out of 10, Wonderful, (1,006 reviews)
"Great stay and property"
United States
Heather
The price is ￥43,232
￥59,319 total
includes taxes & fees
Apr 26 - Apr 27
Claremont Resort & Club
Exterior

The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1,000 reviews)
"Absolutely amazing hotel and service "
United States
Oksana
The price is ￥64,643
￥83,735 total
includes taxes & fees
May 17 - May 18
The Ritz-Carlton, San Francisco
Exterior

The St. Regis San Francisco

The St. Regis San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (723 reviews)
"The hotel staff was so welcoming and took extra care of our two children by bringing surprise cookies and milk to the room, kid size spa robes and slippers and gifts upon checkout. The food at Astra was delicious and the indoor pool was so much fun. "
United States
Margeaux
The price is ￥70,970
￥90,784 total
includes taxes & fees
May 9 - May 10
The St. Regis San Francisco
View from property

The Ritz-Carlton, Half Moon Bay

The Ritz-Carlton, Half Moon Bay
5.0 star property
Ocean Colony
9.0 out of 10, Wonderful, (665 reviews)
"This was an anniversary trip, and the staff made our stay so special!"
United States
Heather
The price is ￥144,904
￥181,447 total
includes taxes & fees
May 17 - May 18
The Ritz-Carlton, Half Moon Bay
Terrace/patio

Four Seasons Hotel Silicon Valley at East Palo Alto

Four Seasons Hotel Silicon Valley at East Palo Alto
5.0 star property
East Palo Alto
9.4 out of 10, Exceptional, (678 reviews)
"wonderful staff, ambience was spot on, we had an overnight stay and all went smooth from start to finish...."
United States
Kimberly
The price is ￥74,939
￥85,202 total
includes taxes & fees
May 9 - May 10
Four Seasons Hotel Silicon Valley at East Palo Alto
Exterior

Rosewood Sand Hill

Rosewood Sand Hill
5.0 star property
Menlo Park
9.4 out of 10, Exceptional, (287 reviews)
"Quite and nice view "
United States
Mei
The price is ￥146,862
￥181,752 total
includes taxes & fees
Apr 25 - Apr 26
Rosewood Sand Hill
Breakfast, lunch, dinner served; Japanese cuisine, alfresco dining

Nobu Hotel Palo Alto

Nobu Hotel Palo Alto
5.0 star property
University South
9.2 out of 10, Wonderful, (445 reviews)
"Beautiful hotel. "
United States
Dianne
The price is ￥71,575
￥82,809 total
includes taxes & fees
May 23 - May 24
Nobu Hotel Palo Alto
Property entrance

Hotel Drisco

Hotel Drisco
5.0 star property
Pacific Heights
9.8 out of 10, Exceptional, (463 reviews)
"Great hotel and would highly recommend "
United States
Oliver
The price is ￥111,314
￥129,472 total
includes taxes & fees
May 21 - May 22
Hotel Drisco
Exterior

Fairmont Heritage Place, Ghirardelli Square

Fairmont Heritage Place, Ghirardelli Square
5.0 star property
Fisherman's Wharf
9.4 out of 10, Exceptional, (400 reviews)
"Wonderful place, I highly recommend staying here!"
United States
Teresa
The price is ￥149,048
￥175,131 total
includes taxes & fees
May 6 - May 7
Fairmont Heritage Place, Ghirardelli Square
Indoor pool

The Huntington Hotel

The Huntington Hotel
5.0 star property
Downtown San Francisco
8.6 out of 10, Excellent, (7 reviews)
"Perfect location, perfect staff. Incredible experience. Get facial if you visit the spa!"
United States
Chas
The price is ￥98,279
￥122,814 total
includes taxes & fees
Apr 25 - Apr 26
The Huntington Hotel
Front of property

Neighbourgood Sutter Mansion

Neighbourgood Sutter Mansion
5.0 star property
Western Addition
9.4 out of 10, Exceptional, (237 reviews)
"Friendly staff, early 1900s decor and architecture."
United States
Louis
The price is ￥49,249
￥63,289 total
includes taxes & fees
Apr 26 - Apr 27
Neighbourgood Sutter Mansion
Deluxe House | Living room | 65-inch Smart TV with digital channels, pay movies, streaming services

Dimond Abode Vacation Rental

Dimond Abode Vacation Rental
5.0 star property
Dimond
10.0 out of 10, Exceptional, (1 review)
"The unit was extremely clean and having access to a garage was definitely a plus for our stay! Nice touches, especially coffee / tea , snacks, and a well equipped kitchen made us feel welcomed the minute we stepped through the door. A+"
United States
Camille
Dimond Abode Vacation Rental
Full-size fridge, microwave, oven, stovetop

Dimond Abode Vacation Rental 3428

Dimond Abode Vacation Rental 3428
5.0 star property
Dimond
9.6 out of 10, Exceptional, (7 reviews)
"Cleanliness, amenities, staff. It was a really great stay."
United States
Phyllis
Dimond Abode Vacation Rental 3428
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in South San Francisco.
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

2500 Mason St San Francisco CA
The price is ￥23,116 per night from May 3 to May 4
￥23,116
￥33,774 total
May 3 - May 4
includes taxes & fees
9/10 Wonderful! (7,372 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about South San Francisco

Perched on the edge of San Francisco Bay, this family-friendly city boasts a surprising castle and stunning mountain views. Foodies flock to local restaurants, while thrill-seekers race go-karts at K1 Speed or tour the famous See's Candies factory.

See all hotels in South San Francisco
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Open Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀

Top South San Francisco Hotel Reviews

Fairmont San Francisco

Fairmont San Francisco

6/10 Okay
"ADA beds too high"
steven paul 2-night trip
Posted 1 day ago
Fairmont San Francisco

Frequently asked questions

What are the best 5-star hotels in South San Francisco?
According to Expedia customer reviews, The St. Regis San Francisco, Four Seasons Hotel San Francisco and Mansion on Sutter are some of the most popular 5-star hotels in South San Francisco. Featuring top-of-the-line amenities and unparalleled service, you'll enjoy a luxurious and memorable stay.
How much does it cost to stay in a 5-star hotel in South San Francisco?
There are a range of pricing options for a 5-star hotel in South San Francisco on Expedia. How much you'll pay will depend on when you travel, length of your trip and other factors. Compare available properties for your preferred dates and use our pricing and other filters to lock in the ideal luxury stay.

  • Search for the lowest price per night from ￥23,694

What makes a hotel 5 stars in South San Francisco?
From high-end restaurants and fitness centers to swimming pools and dreamy bedding, the 5-star experience in South San Francisco is all about comfort and luxury. But it calls for more than just upscale amenities to receive a 5-star rating. Stays must also offer exceptional services like in-room massages, laundry and dry cleaning and a nightly turn-down service.