Find 5 Star Hotels in Northeast Missouri, MO from ￥18,060

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Northeast Missouri 5 Star Hotels

Tonight
Dec 28 - Dec 29
Tomorrow
Dec 29 - Dec 30
Next weekend
Jan 2 - Jan 4
In two weeks
Jan 9 - Jan 11

Our top choices for Northeast Missouri 5-star hotels

Meeting facility
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (554)
"The stay was ok even though nothing was explained to be. The hours of restaurant, where the gym is located about the bar in the room nothing. "
United States
Shemelle
The price is ￥78,128
￥91,204 total
includes taxes & fees
Dec 30 - Dec 31
The Ritz-Carlton, St. Louis
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Northeast Missouri.
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St St. Louis MO
The price is ￥15,187 per night from Jan 25 to Jan 26
￥15,187
￥18,060 total
Jan 25 - Jan 26, 2026
includes taxes & fees
8.6/10 Excellent! (1,171 reviews)
Still don't see what you're looking for?
See all properties in Northeast Missouri.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Northeast Missouri

Great live music, sports teams, and popular sights from St. Louis Union Station to Busch Stadium—explore Northeast Missouri, a family-friendly destination also known for its theaters.

See all hotels in Northeast Missouri
Grant\'s Farm which includes heritage architecture

Top Northeast Missouri Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Northeast Missouri?
You can find a variety of pricing options for 5-star hotels in Northeast Missouri on Expedia. How much you'll pay will depend on when you want to travel, length of stay and other factors. Compare available properties for your chosen dates and make use of our pricing and other filters to score the ideal luxury stay.

  • Search for the lowest price per night from ￥18,060

What makes a hotel 5 stars in Northeast Missouri?
In Northeast Missouri, a hotel must provide a specific level of upscale conveniences to be rated 5 stars. These may include on-site gyms, gourmet restaurants, saunas and spas, premium bedding, complimentary luxury toiletries and more. What also sets 5-star hotels apart is their guest-focused standard of service. You'll enjoy things like concierge services, nightly turn-down services and in-room massage. Some may also offer additional touches like a welcome gift.
Are there any 5-star all-inclusive resorts in Northeast Missouri?
Expedia's filter tool is the easiest way to search for exactly what you're looking for. Select "All inclusive" and "5-star" to see the most upscale hotels in Northeast Missouri where your lodging, meals, activities and entertainment are included in the price. At these escapes, your trip is pure relaxation and indulgence from the moment you check in.

Explore a world of travel with Expedia