Are there any 5-star all-inclusive resorts in Mission District?

Expedia's filter tool is the easiest way to search for exactly what you want. Select "5-star" and "All inclusive" to show the most luxurious resorts in Mission District where your lodging, meals, activities and entertainment are included in the upfront price. At these stays, your vacation is absolute indulgence from the moment you put down your suitcase.

What are the top 5-star spa hotels in Mission District?

Enjoy access to a variety of spa treatments and rejuvenating therapies at 1 Hotel San Francisco . Alternatively, prioritize your well-being and put yourself first at Fairmont San Francisco or Four Seasons Hotel San Francisco . These premium 5-star spa escapes are all located in or around Mission District.

Are there any 5-star vacation rentals in Mission District?

Although there aren't any 5-star vacation rentals in Mission District on our site, we have a range of retreats that promise an awesome getaway. Discover one that suits your needs by checking out our vacation rentals in Mission District .

The Best 5 Star Hotels in Mission District, CA from ￥21,623

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Our top choices for Mission District 5-star hotels

A rooftop terrace with a city skyline, a fountain, and outdoor seating.

1. Fairmont San Francisco

Downtown San Francisco

Anthony

￥57,206 total

includes taxes & fees

Sep 1 - Sep 2

A grand hall with a high arched ceiling and chandeliers, featuring multiple dining tables and chairs arranged for service.

2. Palace Hotel, a Luxury Collection Hotel, San Francisco

Downtown San Francisco

Nicole

￥61,548 total

includes taxes & fees

Sep 19 - Sep 20

A bar area with a marble countertop, leather bar stools, and shelves stocked with bottles and glasses.

3. Taj Campton Place

Union Square

Vince

￥37,792 total

includes taxes & fees

Aug 31 - Sep 1

A terrace with a view, featuring a table and chairs, a potted plant, and a decorative lantern.

4. Claremont Resort & Club

Claremont Hills

amy

￥51,748 total

includes taxes & fees

Aug 31 - Sep 1

A rooftop terrace with tables and potted plants, overlooking a cityscape with a prominent tower and a bridge.

5. Four Seasons Hotel San Francisco at Embarcadero

Downtown San Francisco

"Everything about the stay was first class. We checked in early and and our room was ready. McKenzie was friendly and very helpful at check-in. Our room was clean and beautifully maintained. We frequented the bar downstairs each night of our stay and were treated like royalty by our host Bryce and by our servers Kabin and Anton. To sum up, our stay was outstanding and I'd highly recommend this property to anyone visiting San Francisco,"

William

￥87,684 total

includes taxes & fees

Sep 19 - Sep 20

A grand building with classical architecture, featuring columns and detailed carvings.

6. The Ritz-Carlton, San Francisco

Downtown San Francisco

Simona

￥77,886 total

includes taxes & fees

Sep 4 - Sep 5

A rooftop terrace with outdoor seating, a view of the city skyline, and modern buildings in the background.

7. Four Seasons Hotel San Francisco

Downtown San Francisco

Vasilios

￥73,989 total

includes taxes & fees

Sep 20 - Sep 21

A restaurant with wooden flooring, black chairs, white tables, hanging plants, and pendant lights.

8. 1 Hotel San Francisco

Downtown San Francisco

Ross

￥83,837 total

includes taxes & fees

Sep 20 - Sep 21

A balcony with a view of a tall building, a tree, and a table with chairs.

9. The Huntington Hotel

Downtown San Francisco

Steven

￥155,753 total

includes taxes & fees

Aug 31 - Sep 1

A modern hotel with a glass facade, a covered entrance, and a sign indicating it is a Marriott hotel.

10. The St. Regis San Francisco

Downtown San Francisco

Christopher

￥92,060 total

includes taxes & fees

Sep 3 - Sep 4

A covered outdoor dining area with a wooden deck, a table set for two, and a view of the sea and mountains in the background.

11. Fairmont Heritage Place, Ghirardelli Square

Fisherman's Wharf

Janelle

￥153,357 total

includes taxes & fees

Aug 31 - Sep 1

A grand entrance with a large archway, a staircase, and two wall-mounted light fixtures.

12. Hotel Drisco

Pacific Heights

Tymon

￥119,943 total

includes taxes & fees

Sep 28 - Sep 29

A grand entrance with a staircase leading to a door with a large glass panel, flanked by ornate railings and a well-lit interior.

13. Sutter Mansion

Western Addition

Mary

￥57,405 total

includes taxes & fees

Aug 30 - Aug 31

A modern living room with a black door, a sofa with patterned cushions, a coffee table, and a view of a street with buildings and parked cars.

14. Dimond Abode Vacation Rental

Dimond

Camille

A modern kitchen with stainless steel appliances, a flat-screen TV, and a bar area with bar stools.

15. Dimond Abode Vacation Rental 3428

Dimond

Phyllis

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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mission District.

DoubleTree by Hilton Hotel Berkeley Marina

200 Marina Blvd Berkeley CA

￥18,771

￥21,623 total

Sep 7 - Sep 8

includes taxes & fees

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mission District Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Mission District?

Mansion on Sutter is among the most popular picks around the San Francisco neighborhood of Mission District based on reviews by Expedia customers. Four Seasons Hotel San Francisco and The St. Regis San Francisco are other 5-star hotels in this area that rank highest with travelers.

How much does it cost to stay in a 5-star hotel in Mission District?

There are a range of pricing options for a 5-star hotel in Mission District on Expedia. The amount you pay will depend on your vacation dates, length of your trip and other factors. Compare all of the available accommodations for your chosen dates and use our pricing and other filters to lock in the ideal luxury stay.

Search for the lowest price per night from ￥21,623

What makes a hotel 5 stars in Mission District?

From gourmet dining venues and 24-hour gyms to pools and the finest bedding, the 5-star experience in Mission District is all about indulgence and comfort. But it requires more than just upscale conveniences to earn a 5-star rating. Hotels must also deliver remarkable services like massage treatments, on-site laundry and 24/7 room service.

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