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Find 5 Star Hotels in Mission District, CA from ￥21,364

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Check availability on Mission District 5 Star Hotels

This weekend
Sep 11 - Sep 13
Next weekend
Sep 18 - Sep 20

Our top choices for Mission District 5-star hotels

A rooftop terrace with a city skyline, a fountain, and outdoor seating.

1. Fairmont San Francisco

Fairmont San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (1,573 reviews)
"Excellent location, very clean property and the staff were all fantastic!"
United States
Anthony
The price is ￥50,870
￥68,035 total
includes taxes & fees
Sep 20 - Sep 21
Fairmont San Francisco
A terrace with a view, featuring a table and chairs, a potted plant, and a decorative lantern.

2. Claremont Resort & Club

Claremont Resort & Club
5.0 star property
Claremont Hills
9.0 out of 10, Wonderful, (1,122 reviews)
"My sister had a wonderful stay, just a perfect location!"
United States
Jacqueline
The price is ￥42,869
￥59,476 total
includes taxes & fees
Sep 10 - Sep 11
Claremont Resort & Club
A rooftop terrace with tables and potted plants, overlooking a cityscape with a prominent tower and a bridge.

3. Four Seasons Hotel San Francisco at Embarcadero

Four Seasons Hotel San Francisco at Embarcadero
5.0 star property
Downtown San Francisco
9.6 out of 10, Exceptional, (1,008 reviews)
"The skyline views alone made the stay worth it. Being high above the city, especially at night, gave the hotel a peaceful, private feel even in the middle of San Francisco."
United States
Keeshaun
The price is ￥75,341
￥88,672 total
includes taxes & fees
Oct 2 - Oct 3
Four Seasons Hotel San Francisco at Embarcadero
A grand hall with a high arched ceiling and chandeliers, featuring multiple dining tables and chairs arranged for service.

4. Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (1,002 reviews)
"We stayed here for a wedding and had a great time. Bed was comfortable and spacious."
United States
Nicole
The price is ￥46,900
￥62,436 total
includes taxes & fees
Sep 18 - Sep 19
Palace Hotel, a Luxury Collection Hotel, San Francisco
A grand building with classical architecture, featuring columns, detailed carvings, and a large entrance.

5. The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1,003 reviews)
"Close to everything and the staff was amazing!"
United States
Simona
The price is ￥59,831
￥77,834 total
includes taxes & fees
Sep 18 - Sep 19
The Ritz-Carlton, San Francisco
A restaurant with wooden flooring, black chairs, white tables, hanging plants, and pendant lights.

6. 1 Hotel San Francisco

1 Hotel San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (613 reviews)
"The hotel, the room and the restaurant were very clean. The staff very helpful and it’s very well located."
United States
Gloria
The price is ￥68,975
￥89,864 total
includes taxes & fees
Oct 3 - Oct 4
1 Hotel San Francisco
A bar area with a marble countertop, leather bar stools, and shelves stocked with bottles and glasses.

7. Taj Campton Place

Taj Campton Place
5.0 star property
Union Square
9.2 out of 10, Wonderful, (1,004 reviews)
"Wonderful service, convenient, delicious food!"
United States
Vince
The price is ￥28,284
￥38,653 total
includes taxes & fees
Sep 13 - Sep 14
Taj Campton Place
A rooftop terrace with outdoor seating, a view of the city skyline, and modern buildings in the background.

8. Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1,005 reviews)
"Excellent property and service. Will definitely return!!"
Canada
Vasilios
The price is ￥72,248
￥94,080 total
includes taxes & fees
Sep 19 - Sep 20
Four Seasons Hotel San Francisco
A modern hotel with a glass facade, a covered entrance, and a sign indicating it is a Marriott hotel.

9. The St. Regis San Francisco

The St. Regis San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (738 reviews)
"Great place"
United States
Christopher
The price is ￥73,324
￥93,330 total
includes taxes & fees
Sep 19 - Sep 20
The St. Regis San Francisco
A balcony with a view of a tall building, a tree, and a table with chairs.

10. The Huntington Hotel

The Huntington Hotel
5.0 star property
Downtown San Francisco
9.6 out of 10, Exceptional, (34 reviews)
"Perfect weekend stay. A great hotel.....happy it's back in operation after many years! Highly recommend!"
United States
Steven
The price is ￥120,488
￥149,951 total
includes taxes & fees
Oct 4 - Oct 5
The Huntington Hotel
A grand entrance with a large archway, a staircase, and two wall-mounted light fixtures.

11. Hotel Drisco

Hotel Drisco
5.0 star property
Pacific Heights
9.8 out of 10, Exceptional, (474 reviews)
"Beautiful old historic hotel at a wonderful setting"
United States
Tymon
The price is ￥103,622
￥120,526 total
includes taxes & fees
Oct 1 - Oct 2
Hotel Drisco
A covered outdoor dining area with a wooden deck, a table set for two, and a view of the sea and mountains in the background.

12. Fairmont Heritage Place, Ghirardelli Square

Fairmont Heritage Place, Ghirardelli Square
5.0 star property
Fisherman's Wharf
9.4 out of 10, Exceptional, (415 reviews)
"Excellent location and rooms - great space for families. Very helpful and friendly staff."
United States
Janelle
The price is ￥157,563
￥185,136 total
includes taxes & fees
Sep 20 - Sep 21
Fairmont Heritage Place, Ghirardelli Square
A historic building with ornate architectural details, large windows, and a well-lit entrance.

13. Sutter Mansion

Sutter Mansion
5.0 star property
Western Addition
9.4 out of 10, Exceptional, (244 reviews)
"The location is so beautiful - a Victorian style mansion. the staff were all so kind and polite and room was lovely. Breakfast was delicious as well."
United States
Stewart
The price is ￥42,286
￥54,341 total
includes taxes & fees
Sep 20 - Sep 21
Sutter Mansion
A modern living room with a black door, a sofa with patterned cushions, a coffee table, and a view of a street with buildings and parked cars.

14. Dimond Abode Vacation Rental

Dimond Abode Vacation Rental
5.0 star property
Dimond
10.0 out of 10, Exceptional, (2 reviews)
"The unit was extremely clean and having access to a garage was definitely a plus for our stay! Nice touches, especially coffee / tea , snacks, and a well equipped kitchen made us feel welcomed the minute we stepped through the door. A+"
United States
Camille
Dimond Abode Vacation Rental
A modern kitchen with stainless steel appliances, a flat-screen TV, and a bar area with bar stools.

15. Dimond Abode Vacation Rental 3428

Dimond Abode Vacation Rental 3428
5.0 star property
Dimond
9.6 out of 10, Exceptional, (7 reviews)
"Cleanliness, amenities, staff. It was a really great stay."
United States
Phyllis
Dimond Abode Vacation Rental 3428
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mission District.
Grand Hyatt San Francisco

Grand Hyatt San Francisco

345 Stockton St San Francisco CA
The price is ￥23,980 per night from Oct 3 to Oct 4
￥23,980
￥35,460 total
Oct 3 - Oct 4
includes taxes & fees
9/10 Wonderful! (1,030 reviews)
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Top Mission District Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Mission District?
Mansion on Sutter is among the most popular picks around the San Francisco neighborhood of Mission District based on reviews by Expedia customers. Four Seasons Hotel San Francisco and The St. Regis San Francisco are other 5-star hotels in this area that rank highest with travelers.
How much does it cost to stay in a 5-star hotel in Mission District?
There are a range of pricing options for a 5-star hotel in Mission District on Expedia. The amount you pay will depend on your vacation dates, length of your trip and other factors. Compare all of the available accommodations for your chosen dates and use our pricing and other filters to lock in the ideal luxury stay.

  • Search for the lowest price per night from ￥21,364

What makes a hotel 5 stars in Mission District?
From gourmet dining venues and 24-hour gyms to pools and the finest bedding, the 5-star experience in Mission District is all about indulgence and comfort. But it requires more than just upscale conveniences to earn a 5-star rating. Hotels must also deliver remarkable services like massage treatments, on-site laundry and 24/7 room service.