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Check availability on Mission District 5 Star Hotels

Our top choices for Mission District 5-star hotels

Terrace/patio

Fairmont San Francisco

Fairmont San Francisco
5.0 star property
Downtown San Francisco
9.0 out of 10, Wonderful, (1,474 reviews)
"Nice overall stay."
Canada
Danielle
The price is ￥31,720
￥44,548 total
includes taxes & fees
Mar 6 - Mar 7
Fairmont San Francisco
Terrace/patio

Claremont Resort & Club

Claremont Resort & Club
5.0 star property
Claremont Hills
8.8 out of 10, Excellent, (1,000 reviews)
"Great stay "
United States
sheharyar
The price is ￥30,176
￥43,798 total
includes taxes & fees
Feb 16 - Feb 17
Claremont Resort & Club
View from property

Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (1,000 reviews)
"Stand outs: the staff, the pool, the polar bear Christmas decorations, and close to restaurants. "
United States
Janet
The price is ￥42,616
￥50,157 total
includes taxes & fees
Feb 20 - Feb 21
Palace Hotel, a Luxury Collection Hotel, San Francisco
Bar (on property)

Taj Campton Place

Taj Campton Place
5.0 star property
Union Square
9.2 out of 10, Wonderful, (1,000 reviews)
"It was a perfect stay"
Canada
Travel To Explore
The price is ￥27,277
￥37,395 total
includes taxes & fees
Feb 16 - Feb 17
Taj Campton Place
Terrace/patio

Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1,007 reviews)
"great location, amazing hotel. great rooms. wonderful staff "
United States
Majd
The price is ￥62,062
￥73,043 total
includes taxes & fees
Mar 6 - Mar 7
Four Seasons Hotel San Francisco
Exterior

The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1,000 reviews)
"Impeccable service, beautiful property, and great food and drinks in the lobby lounge."
United States
Michael
The price is ￥62,392
￥80,819 total
includes taxes & fees
Feb 22 - Feb 23
The Ritz-Carlton, San Francisco
Breakfast, lunch, dinner served; alfresco dining

1 Hotel San Francisco

1 Hotel San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (511 reviews)
"We loved our stay!"
United States
Michelle
The price is ￥69,877
￥90,899 total
includes taxes & fees
Mar 6 - Mar 7
1 Hotel San Francisco
Rooftop terrace

Four Seasons Hotel San Francisco at Embarcadero

Four Seasons Hotel San Francisco at Embarcadero
5.0 star property
Downtown San Francisco
9.6 out of 10, Exceptional, (1,000 reviews)
"Very friendly staff and overall had a great visit"
United States
Michael
The price is ￥64,894
￥76,377 total
includes taxes & fees
Mar 13 - Mar 14
Four Seasons Hotel San Francisco at Embarcadero
Exterior

The St. Regis San Francisco

The St. Regis San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (709 reviews)
"The service was spectacular, enjoyed the restaurant as well as room service, and the room was very clean and spacious "
United States
Lauren
The price is ￥61,909
￥79,856 total
includes taxes & fees
Feb 20 - Feb 21
The St. Regis San Francisco
Property entrance

Hotel Drisco

Hotel Drisco
5.0 star property
Pacific Heights
9.8 out of 10, Exceptional, (458 reviews)
"Service and breakfast "
Canada
Michael
The price is ￥86,343
￥100,429 total
includes taxes & fees
Mar 15 - Mar 16
Hotel Drisco
Exterior

Fairmont Heritage Place, Ghirardelli Square

Fairmont Heritage Place, Ghirardelli Square
5.0 star property
Fisherman's Wharf
9.4 out of 10, Exceptional, (387 reviews)
"Great staff, clean, excellent location, spacious rooms"
United States
Christopher
The price is ￥124,381
￥146,148 total
includes taxes & fees
Mar 5 - Mar 6
Fairmont Heritage Place, Ghirardelli Square
Front of property

Neighbourgood Sutter Mansion

Neighbourgood Sutter Mansion
5.0 star property
Western Addition
9.4 out of 10, Exceptional, (233 reviews)
"helpful staff, especially Amanda"
United States
Mark A.
The price is ￥49,833
￥65,027 total
includes taxes & fees
Feb 22 - Feb 23
Neighbourgood Sutter Mansion
Full-size fridge, microwave, oven, stovetop

Dimond Abode Vacation Rental 3428

Dimond Abode Vacation Rental 3428
5.0 star property
Dimond
9.6 out of 10, Exceptional, (7 reviews)
"Cleanliness, amenities, staff. It was a really great stay."
United States
Phyllis
Dimond Abode Vacation Rental 3428
Deluxe House | Living room | 65-inch Smart TV with digital channels, pay movies, streaming services

Dimond Abode Vacation Rental

Dimond Abode Vacation Rental
5.0 star property
Dimond
10.0 out of 10, Exceptional, (1 review)
"The unit was extremely clean and having access to a garage was definitely a plus for our stay! Nice touches, especially coffee / tea , snacks, and a well equipped kitchen made us feel welcomed the minute we stepped through the door. A+"
United States
Camille
Dimond Abode Vacation Rental
Studio (4 Bedrooms) | Exterior

KBM Resorts Long Term Lease 4 Bed/3 Bath Luxury Home Pool, Bbq, Fitness Center Orinda Retreat Ldd-32

KBM Resorts Long Term Lease 4 Bed/3 Bath Luxury Home Pool, Bbq, Fitness Center Orinda Retreat Ldd-32
5.0 star property
Orinda
KBM Resorts Long Term Lease 4 Bed/3 Bath Luxury Home Pool, Bbq, Fitness Center Orinda Retreat Ldd-32
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mission District.
Hyatt Regency San Francisco

Hyatt Regency San Francisco

5 Embarcadero Center San Francisco CA
The price is ￥27,430 per night from Mar 6 to Mar 7
￥27,430
￥39,328 total
Mar 6 - Mar 7
includes taxes & fees
9.2/10 Wonderful! (2,066 reviews)
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Top Mission District Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Mission District?
Mansion on Sutter is among the most popular picks around the San Francisco neighborhood of Mission District based on reviews by Expedia customers. Four Seasons Hotel San Francisco and The St. Regis San Francisco are other 5-star hotels in this area that rank highest with travelers.
How much does it cost to stay in a 5-star hotel in Mission District?
There are a range of pricing options for a 5-star hotel in Mission District on Expedia. The amount you pay will depend on your vacation dates, length of your trip and other factors. Compare all of the available accommodations for your chosen dates and use our pricing and other filters to lock in the ideal luxury stay.

  • Search for the lowest price per night from ￥22,778

What makes a hotel 5 stars in Mission District?
From gourmet dining venues and 24-hour gyms to pools and the finest bedding, the 5-star experience in Mission District is all about indulgence and comfort. But it requires more than just upscale conveniences to earn a 5-star rating. Hotels must also deliver remarkable services like massage treatments, on-site laundry and 24/7 room service.