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Find 5 Star Hotels in Mission District, CA from ￥21,715

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Check availability on Mission District 5 Star Hotels

Next weekend
Sep 11 - Sep 13
In two weeks
Sep 18 - Sep 20

Our top choices for Mission District 5-star hotels

Terrace/patio

1. Fairmont San Francisco

Fairmont San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (1,573 reviews)
"Excellent location, very clean property and the staff were all fantastic!"
United States
Anthony
The price is ￥42,972
￥58,853 total
includes taxes & fees
Sep 7 - Sep 8
Fairmont San Francisco
Terrace/patio

2. Claremont Resort & Club

Claremont Resort & Club
5.0 star property
Claremont Hills
9.0 out of 10, Wonderful, (1,113 reviews)
"My sister had a wonderful stay, just a perfect location!"
United States
Jacqueline
The price is ￥40,643
￥57,023 total
includes taxes & fees
Sep 7 - Sep 8
Claremont Resort & Club
Rooftop terrace

3. Four Seasons Hotel San Francisco at Embarcadero

Four Seasons Hotel San Francisco at Embarcadero
5.0 star property
Downtown San Francisco
9.6 out of 10, Exceptional, (1,006 reviews)
"The skyline views alone made the stay worth it. Being high above the city, especially at night, gave the hotel a peaceful, private feel even in the middle of San Francisco."
United States
Keeshaun
The price is ￥73,052
￥85,979 total
includes taxes & fees
Sep 19 - Sep 20
Four Seasons Hotel San Francisco at Embarcadero
View from property

4. Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (1,001 reviews)
"We stayed here for a wedding and had a great time. Bed was comfortable and spacious."
United States
Nicole
The price is ￥47,675
￥63,468 total
includes taxes & fees
Sep 18 - Sep 19
Palace Hotel, a Luxury Collection Hotel, San Francisco
Exterior

5. The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1,002 reviews)
"Close to everything and the staff was amazing!"
United States
Simona
The price is ￥60,820
￥79,119 total
includes taxes & fees
Sep 18 - Sep 19
The Ritz-Carlton, San Francisco
Restaurant

6. 1 Hotel San Francisco

1 Hotel San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (611 reviews)
"Great hotel! Great service! Great location!"
United States
David
The price is ￥70,114
￥91,348 total
includes taxes & fees
Sep 12 - Sep 13
1 Hotel San Francisco
Bar (on property)

7. Taj Campton Place

Taj Campton Place
5.0 star property
Union Square
9.2 out of 10, Wonderful, (1,003 reviews)
"Wonderful service, convenient, delicious food!"
United States
Vince
The price is ￥31,627
￥42,670 total
includes taxes & fees
Sep 7 - Sep 8
Taj Campton Place
Terrace/patio

8. Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1,005 reviews)
"Excellent property and service. Will definitely return!!"
Canada
Vasilios
The price is ￥67,192
￥88,279 total
includes taxes & fees
Sep 20 - Sep 21
Four Seasons Hotel San Francisco
Exterior

9. The St. Regis San Francisco

The St. Regis San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (738 reviews)
"Great place"
United States
Christopher
The price is ￥68,129
￥87,322 total
includes taxes & fees
Sep 19 - Sep 20
The St. Regis San Francisco
Spa

10. The Huntington Hotel

The Huntington Hotel
5.0 star property
Downtown San Francisco
9.6 out of 10, Exceptional, (34 reviews)
"Perfect weekend stay. A great hotel.....happy it's back in operation after many years! Highly recommend!"
United States
Steven
The price is ￥124,852
￥155,222 total
includes taxes & fees
Sep 7 - Sep 8
The Huntington Hotel
Property entrance

11. Hotel Drisco

Hotel Drisco
5.0 star property
Pacific Heights
9.8 out of 10, Exceptional, (474 reviews)
"Beautiful old historic hotel at a wonderful setting"
United States
Tymon
The price is ￥105,335
￥122,517 total
includes taxes & fees
Sep 21 - Sep 22
Hotel Drisco
Exterior

12. Fairmont Heritage Place, Ghirardelli Square

Fairmont Heritage Place, Ghirardelli Square
5.0 star property
Fisherman's Wharf
9.4 out of 10, Exceptional, (415 reviews)
"Excellent location and rooms - great space for families. Very helpful and friendly staff."
United States
Janelle
The price is ￥152,354
￥179,016 total
includes taxes & fees
Sep 7 - Sep 8
Fairmont Heritage Place, Ghirardelli Square
Front of property - evening/night

13. Sutter Mansion

Sutter Mansion
5.0 star property
Western Addition
9.4 out of 10, Exceptional, (244 reviews)
"The location is so beautiful - a Victorian style mansion. the staff were all so kind and polite and room was lovely. Breakfast was delicious as well."
United States
Stewart
The price is ￥42,986
￥55,240 total
includes taxes & fees
Sep 20 - Sep 21
Sutter Mansion
Deluxe House | Living room

14. Dimond Abode Vacation Rental

Dimond Abode Vacation Rental
5.0 star property
Dimond
10.0 out of 10, Exceptional, (2 reviews)
"The unit was extremely clean and having access to a garage was definitely a plus for our stay! Nice touches, especially coffee / tea , snacks, and a well equipped kitchen made us feel welcomed the minute we stepped through the door. A+"
United States
Camille
Dimond Abode Vacation Rental
Private kitchen

15. Dimond Abode Vacation Rental 3428

Dimond Abode Vacation Rental 3428
5.0 star property
Dimond
9.6 out of 10, Exceptional, (7 reviews)
"Cleanliness, amenities, staff. It was a really great stay."
United States
Phyllis
Dimond Abode Vacation Rental 3428
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mission District.
Grand Hyatt San Francisco

Grand Hyatt San Francisco

345 Stockton St San Francisco CA
The price is ￥24,377 per night from Oct 2 to Oct 3
￥24,377
￥36,047 total
Oct 2 - Oct 3
includes taxes & fees
9/10 Wonderful! (1,025 reviews)
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Top Mission District Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Mission District?
Mansion on Sutter is among the most popular picks around the San Francisco neighborhood of Mission District based on reviews by Expedia customers. Four Seasons Hotel San Francisco and The St. Regis San Francisco are other 5-star hotels in this area that rank highest with travelers.
How much does it cost to stay in a 5-star hotel in Mission District?
There are a range of pricing options for a 5-star hotel in Mission District on Expedia. The amount you pay will depend on your vacation dates, length of your trip and other factors. Compare all of the available accommodations for your chosen dates and use our pricing and other filters to lock in the ideal luxury stay.

  • Search for the lowest price per night from ￥21,715

What makes a hotel 5 stars in Mission District?
From gourmet dining venues and 24-hour gyms to pools and the finest bedding, the 5-star experience in Mission District is all about indulgence and comfort. But it requires more than just upscale conveniences to earn a 5-star rating. Hotels must also deliver remarkable services like massage treatments, on-site laundry and 24/7 room service.