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Our top choices for Santa Clara hotels

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
Tocumen
8.6 out of 10, Excellent, (2,388 reviews)
"Great staff and close to the airport "
United States
CARLOS ROBERTO
The price is ¥17,259
¥18,985 total
includes taxes & fees
Jan 15 - Jan 16
Crowne Plaza Panama Airport by IHG

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.6 out of 10, Excellent, (1,845 reviews)
"Better than expected: Location, transportation to and from airport, pool area tropical and comfortable. "
United States
Marty
The price is ¥19,621
¥21,583 total
includes taxes & fees
Jan 26 - Jan 27
Riande Aeropuerto Hotel & Casino

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (650 reviews)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is ¥41,069
¥45,177 total
includes taxes & fees
Feb 6 - Feb 7
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (4,809 reviews)
"Great place to stay"
United States
Maria Teresa
The price is ¥19,213
¥21,134 total
includes taxes & fees
Jan 18 - Jan 19
Hotel Riu Plaza Panama

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
San Antonio
8.8 out of 10, Excellent, (1,004 reviews)
"Very courteous staff - early check in - room clean "
United States
Arthur
The price is ¥15,870
¥17,457 total
includes taxes & fees
Feb 6 - Feb 7
Courtyard by Marriott Panama Metromall

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador
8.6 out of 10, Excellent, (1,002 reviews)
"Unbeatable location if your visit is all about the Panama Canal. "
United States
Vitaliy
The price is ¥11,810
¥12,991 total
includes taxes & fees
Feb 7 - Feb 8
Radisson Hotel Panama Canal

Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,645 reviews)
"A easy and convenient stay"
United States
Dave
The price is ¥9,178
¥10,096 total
includes taxes & fees
Jan 15 - Jan 16
Principe Hotel and Suites

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,004 reviews)
"Great Hotel and great staff"
United States
Rudolph
The price is ¥44,051
¥48,457 total
includes taxes & fees
Feb 7 - Feb 8
JW Marriott Panama

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,001 reviews)
"Beautiful room, super clean, and friendly staff!!!"
United States
Kimberly
The price is ¥31,254
¥34,380 total
includes taxes & fees
Jan 30 - Jan 31
W Panama

The Executive Hotel

The Executive Hotel
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (1,003 reviews)
"A nice hotel to stay great location"
United States
angela
The Executive Hotel

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,012 reviews)
"Great hotel. Great spa"
United States
Robert
The price is ¥21,182
¥23,300 total
includes taxes & fees
Jan 13 - Jan 14
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,140 reviews)
"The room was clean and the location was great."
United States
Wendy
The price is ¥17,071
¥18,778 total
includes taxes & fees
Jan 13 - Jan 14
Ramada Plaza by Wyndham Panama Punta Pacifica

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Bella Vista
9.8 out of 10, Exceptional, (163 reviews)
"Breakfast was so good , hotel was clean "
United States
ankit
The price is ¥24,749
¥27,224 total
includes taxes & fees
Jan 11 - Jan 12
Hyatt Regency Panama City

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,149 reviews)
"Great location of the hotel with a lovely breakfast and friendly staff"
United States
fouad
The price is ¥17,715
¥19,487 total
includes taxes & fees
Jan 24 - Jan 25
Plaza Paitilla Inn Hotel

Riande Urban Hotel

Riande Urban Hotel
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,049 reviews)
"Good hotel and nice staff"
United States
Jose
The price is ¥13,196
¥14,516 total
includes taxes & fees
Jan 13 - Jan 14
Riande Urban Hotel

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (188 reviews)
"Was a great buy. Beautiful views and spacious rooms. Great amenities. "
United States
Lesley
The price is ¥12,991
¥21,539 total
includes taxes & fees
Feb 9 - Feb 10
Arcadia Condo Suites

Magnolia Inn

Magnolia Inn
2.0 star property
Casco Viejo
8.8 out of 10, Excellent, (424 reviews)
"Excelent location , friendly staff and cute hotel"
Canada
Renata
The price is ¥11,822
¥13,004 total
includes taxes & fees
Jan 11 - Jan 12
Magnolia Inn

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,490 reviews)
"Great place! "
Mexico
Bridget
The price is ¥17,989
¥19,788 total
includes taxes & fees
Jan 25 - Jan 26
Decapolis Hotel Panama City

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very Good, (1,362 reviews)
"Lovely breakfast and very clean and friendly staff!!!"
United States
Ravindra
The price is ¥30,914
¥34,005 total
includes taxes & fees
Jan 28 - Jan 29
Megapolis Hotel Panamá

The Beach House

The Beach House
3.0 star property
Amador
8.4 out of 10, Very Good, (411 reviews)
"Fantastic location on Amador Causeway and access to paddleboarding, restaurants, nightlife and family friendly events. One cool sloth in the tree overhanging the walkway at the Culebra nature area right by the prroperty."
United States
Cynthia
The Beach House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place for a stay in Santa Clara?
Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Megapolis Hotel Panamá and Las Americas Golden Tower Panama. See all available top hotels, or vacation rentals in Santa Clara.
What's the top vacation rental in Santa Clara?
Oasis with pool near panama canal: This vacation home rental outside of Santa Clara offers an outdoor pool, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the garden in this rental home to help you unwind. See all vacation rentals in Santa Clara.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.
Where can I learn more about changing or cancelling my trip to Santa Clara?
To access more information about rescheduling or cancelling your trip to Santa Clara, go to https://www.expedia.com/service/.
What's the best place to stay near Culebra Cut?
Gamboa Rainforest Reserve is one of the top choices for your stay based on our traveler data, and this 3.5-star hotel offers a marina and a full-service spa. It's located 2.9 mi (4.7 km) from Culebra Cut. Other good options within 5 miles include Canopy Bed & Breakfast and Casa en Gamboa al lado Canal de Panama.
What is staying in Santa Clara like?
Visitors can enjoy all that Santa Clara has to offer including its monuments. A top sight in the area is Albrook Shopping Mall. There are 1684 hotels and other accommodations in the surrounding area. Find out more about Santa Clara.
What is there to see in Santa Clara?
A favorite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall in the area. Check out what more to see and do in Expedia's Santa Clara guide.
What's the seasonal weather like in Santa Clara?
The hottest months are usually April and March with an average temp of 79°F, while the coldest months are January and February with an average of 78°F. The rainiest months in Santa Clara are July, August, November, and October, with each month seeing an average of 11 inches of rainfall.