Upstate South Carolina Beach Vacations 2026

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Top Beach Upstate South Carolina Hotels

😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks

Seneca SC

21 min drive from Clemson University

Lounge by the shoreline in Seneca, as you'll be a short walk from the beach when booking a getaway at this vacation home. Beach towels and sun loungers are just ...

10/10 Exceptional! (249 reviews)

Travelers like: on the beach, sun loungers, beach towels

Travelers say...

"We really enjoyed our stay! A great secluded and well equipped place and within reasonable distance to Clemson for parents weekend. Highly recommend!"

Reviewed on Sep 29, 2026

Quality Inn Clinton - Laurens I-26

105 Trade St Clinton SC

3 hours drive from Clemson University

Book a stay at this business-friendly hotel in Clinton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

801 Spartan Blvd Spartanburg SC

2 hours drive from Clemson University

Stay at this hotel in Spartanburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...

8.6/10 Excellent! (1,001 reviews)

"Great place to stop, restaurants within walking distance plus mall."

Reviewed on Oct 2, 2026

See all 3,083 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.